公开(公告)号：US20090099551A1

公开(公告)日：2009-04-16

申请号：US12151963

申请日：2008-05-09

申请人： Alexander Tung ,  Gunter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

发明人： Alexander Tung ,  Gunter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

IPC分类号： A61M25/00

CPC分类号： A61B5/103 ,  A61B5/6852 ,  A61B5/6885 ,  A61B5/7455 ,  A61B2034/2061 ,  A61B2562/0252 ,  A61B2562/0261 ,  A61B2562/0266 ,  A61B2562/043

摘要： This invention provides small position sensors for applications where localized sensing in a small volume of space is needed but where measurement of large relative displacement is also necessary. The invention enables a surgeon to accurately position the tip of a catheter during minimally invasive therapy. The current invention further improves the quality of tactile feedback to a physician during catheter-based surgeries with an axial force sensor at the tip of the catheter that allows for the transmission of force information to the physician. One embodiment of this invention is a position sensor for active interventional catheters, where the sensor may be laser-machined shape memory alloy (SMA), and the catheter actuators may be heated SMA or wire-pulleys. Providing position feedback from a catheter during minimally invasive therapy allows for closed-loop control of the catheter tip position under computer-aided guidance and enable force feedback to the physician.

摘要翻译： 本发明提供小型位置传感器，用于需要在小体积空间中进行局部感测但也需要测量大的相对位移的应用。 本发明使得外科医生能够在微创治疗期间精确地定位导管的尖端。 本发明进一步提高了在基于导管的手术过程中对医生的触觉反馈的质量，其中导管的尖端处的轴向力传感器允许向医师传递力信息。 本发明的一个实施例是用于主动介入导管的位置传感器，其中传感器可以是激光加工的形状记忆合金（SMA），并且导管致动器可以被加热SMA或线滑轮。 在微创治疗期间从导管提供位置反馈允许在计算机辅助引导下对导管尖端位置进行闭环控制，并使能力反馈给医师。

公开(公告)号：US20070037445A1

公开(公告)日：2007-02-15

申请号：US11487152

申请日：2006-07-13

申请人： Byong-Ho Park ,  David Liang

发明人： Byong-Ho Park ,  David Liang

IPC分类号： H01R9/05

CPC分类号： F03G7/065 ,  A61M25/0105 ,  H01R4/01 ,  H01R13/5224

摘要： A shape memory alloy (SMA) actuator made from tubular structures is disclosed. The current invention is a tubular monolithic SMA actuator made from a tubular monolithic SMA substrate of NiTi, CuAlNi, CuAl, CuZnAl, TiV, or TiNb. The tubular monolithic SMA actuator has a first end, a second end and a middle portion, and can be made out or a substrate with a cross-section shape such as a circle, an ellipse, a rectangle or any irregular shape. The middle portion is formed into an actuator pattern that maintains unity and electrical continuity, along the path of the actuator pattern, with the first end and second end. The actuator pattern can be any number of patterns, for example, a Greek key pattern or a zigzag pattern. A first electrode is optionally formed in the first end and a second electrode is formed in the second end of the tubular monolithic SMA actuator.

摘要翻译： 公开了一种由管状结构制成的形状记忆合金（SMA）致动器。 本发明是由NiTi，CuAlNi，CuAl，CuZnAl，TiV或TiNb的管状单片SMA基片制成的管状单片SMA致动器。 管状单片SMA致动器具有第一端，第二端和中间部分，并且可以制成具有诸如圆形，椭圆形，矩形或任何不规则形状的横截面形状的基板。 中间部分形成为致动器图案，其沿着致动器图案的路径与第一端和第二端保持单一和电连续性。 致动器图案可以是任何数量的图案，例如，希腊键图案或之字形图案。 第一电极任选地形成在第一端中，并且第二电极形成在管状单片SMA致动器的第二端中。

公开(公告)号：US08347738B2

公开(公告)日：2013-01-08

申请号：US12151963

申请日：2008-05-09

申请人： Alexander Tung ,  Günter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

发明人： Alexander Tung ,  Günter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

IPC分类号： G01L1/22

CPC分类号： A61B5/103 ,  A61B5/6852 ,  A61B5/6885 ,  A61B5/7455 ,  A61B2034/2061 ,  A61B2562/0252 ,  A61B2562/0261 ,  A61B2562/0266 ,  A61B2562/043

摘要： This invention provides small position sensors for applications where localized sensing in a small volume of space is needed but where measurement of large relative displacement is also necessary. The invention enables a surgeon to accurately position the tip of a catheter during minimally invasive therapy. The current invention further improves the quality of tactile feedback to a physician during catheter-based surgeries with an axial force sensor at the tip of the catheter that allows for the transmission of force information to the physician. One embodiment of this invention is a position sensor for active interventional catheters, where the sensor may be laser-machined shape memory alloy (SMA), and the catheter actuators may be heated SMA or wire-pulleys. Providing position feedback from a catheter during minimally invasive therapy allows for closed-loop control of the catheter tip position under computer-aided guidance and enable force feedback to the physician.

公开(公告)号：US20070167804A1

公开(公告)日：2007-07-19

申请号：US11510134

申请日：2006-08-24

申请人： Byong-Ho Park ,  Stephen Rudy ,  Friedrich Prinz ,  David Liang

发明人： Byong-Ho Park ,  Stephen Rudy ,  Friedrich Prinz ,  David Liang

IPC分类号： A61B1/00

CPC分类号： A61B8/12 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/6852 ,  A61B8/4416 ,  A61B8/445 ,  A61B8/4472 ,  A61B18/1492 ,  A61B2017/320069 ,  A61B2017/32007 ,  A61B2018/00214 ,  A61B2018/00898

摘要： A micromanipulator comprising a tubular structure and a structural compliance mechanism that are formed from a tube made of an elastic and/or superelastic material. The micromanipulator is useful for intravascular interventional applications and particularly ultrasonic imaging when coupled with an ultrasound transducer. Also disclosed are medical devices for crossing vascular occlusions using radio-frequency energy or rotary cutting, preferably under the guidance of real-time imaging of the occlusion, as well as accompanying methods.

摘要翻译： 一种显微操纵器，其包括由弹性和/或超弹性材料制成的管形成的管状结构和结构顺应性机构。 显微操纵器可用于血管内介入应用，特别是与超声波换能器耦合时的超声波成像。 还公开了用于使用射频能量或旋转切割交叉血管闭塞的医疗装置，优选地在闭塞的实时成像的指导下以及伴随的方法。

公开(公告)号：US20060030777A1

公开(公告)日：2006-02-09

申请号：US11191311

申请日：2005-07-28

申请人： David Liang ,  Phillip Yang ,  Aditya Koolwal ,  Byong-Ho Park

发明人： David Liang ,  Phillip Yang ,  Aditya Koolwal ,  Byong-Ho Park

IPC分类号： A61B8/00

CPC分类号： A61B8/12 ,  G06T5/008 ,  G06T5/50 ,  G06T7/0012 ,  G06T2207/10132 ,  G06T2207/30101

摘要： A technique for enhancing the image quality in intravascular ultrasound imaging increases contrast between blood and vessel wall processes image data using a point-wise t-statistic technique. Data from an ultrasound transducer is digitized and stored in a memory buffer [500]. For each point in the image, a t-statistic value is derived from signal amplitude values for the same point at a sequence of previous frames [502]. An image is then generated and displayed using the t-statistic values for the intensity of each point [504]. The improvement in contrast ratio as compared to averaging techniques is most significant at highly oblique angles when contrast ratio is particularly poor in the unprocessed signal.

摘要翻译： 一种增强血管内超声成像图像质量的技术增加血液和血管壁之间的对比，使用点式t统计技术对图像数据进行对比。 来自超声换能器的数据被数字化并存储在存储器缓冲器[500]中。 对于图像中的每个点，从先前帧序列的相同点的信号振幅值导出t统计值[502]。 然后使用每个点的强度的t统计值来生成和显示图像[504]。 与平均化技术相比，对比度的改善在高度倾斜的角度是最显着的，当未处理信号的对比度比特别差时。

公开(公告)号：US08454519B2

公开(公告)日：2013-06-04

申请号：US12992814

申请日：2009-05-15

申请人： Byong-Ho Park ,  Oren Levy

发明人： Byong-Ho Park ,  Oren Levy

IPC分类号： A61B8/12 ,  A61B8/14

CPC分类号： A61B8/4466 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/445 ,  A61B8/12 ,  A61B8/4444 ,  A61B8/445 ,  A61B8/4461 ,  A61B8/4494 ,  G01S7/52079 ,  G01S15/894 ,  Y10T29/49005

摘要： The present invention relates to a new forward-looking ultrasound device including a local actuator embedded inside an elongate member such as a guide wire or catheter. The present invention includes an ultrasound transducer element configured to engage with the local actuator and rotate about an axis of rotation at least when the ultrasound transducer element and the local actuator are engaged. Also disclosed are methods of using the same.

公开(公告)号：US20110263986A1

公开(公告)日：2011-10-27

申请号：US12992814

申请日：2009-05-15

申请人： Byong-Ho Park ,  Oren Levy

发明人： Byong-Ho Park ,  Oren Levy

IPC分类号： A61B8/14

CPC分类号： A61B8/4466 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/445 ,  A61B8/12 ,  A61B8/4444 ,  A61B8/445 ,  A61B8/4461 ,  A61B8/4494 ,  G01S7/52079 ,  G01S15/894 ,  Y10T29/49005

摘要： The present invention relates to a new forward-looking ultrasound device including a local actuator embedded inside an elongate member such as a guide wire or catheter. The present invention includes an ultrasound transducer element configured to engage with the local actuator and rotate about an axis of rotation at least when the ultrasound transducer element and the local actuator are engaged. Also disclosed are methods of using the same.

摘要翻译： 本发明涉及一种新的前视超声波装置，其包括嵌入在例如导丝或导管的细长构件内部的局部致动器。 本发明包括超声波换能器元件，其构造成至少当超声换能器元件和局部致动器接合时，与本地致动器接合并围绕旋转轴线旋转。 还公开了使用该方法的方法。

公开(公告)号：US07658715B2

公开(公告)日：2010-02-09

申请号：US11415855

申请日：2006-05-02

申请人： Byong-Ho Park ,  Stephen M. Rudy

发明人： Byong-Ho Park ,  Stephen M. Rudy

IPC分类号： A61B8/14

CPC分类号： A61B8/4461 ,  A61B5/0066 ,  A61B5/02007 ,  A61B8/12 ,  A61B8/145 ,  A61B8/445 ,  A61B8/4483 ,  A61B2090/3614 ,  A61B2090/3784 ,  A61M25/0138 ,  A61M25/0158 ,  F16C2202/28 ,  G01S7/52079 ,  G01S15/8943 ,  G10K11/004

摘要： The present invention relates to a new intravascular imaging device based on a Shape Memory Alloy (SMA) actuator mechanism embedded inside an elongate member such as a guide wire or catheter. The present invention utilizes a novel SMA mechanism to provide side-looking imaging by providing movement for an ultrasound transducer element. This novel SMA actuator mechanism can be easily fabricated in micro-scale, providing an advantage over existing imaging devices because it offers the ability to miniaturize the overall size of the device, while the use of multiple transducer crystals maximizes field of view. Also disclosed are methods of using the same.

摘要翻译： 本发明涉及一种基于形状记忆合金（SMA）致动器机构的新的血管内成像装置，其嵌入诸如导丝或导管的细长构件内部。 本发明利用一种新颖的SMA机制来提供超声换能器元件的移动来提供侧视成像。 这种新颖的SMA致动器机构可以容易地以微尺度制造，提供了优于现有成像装置的优点，因为它提供了使装置的整体尺寸小型化的能力，而多个换能器晶体的使用使视野最大化。 还公开了使用该方法的方法。

公开(公告)号：US08187193B2

公开(公告)日：2012-05-29

申请号：US12687025

申请日：2010-01-13

申请人： Byong-Ho Park ,  Stephen M. Rudy

发明人： Byong-Ho Park ,  Stephen M. Rudy

IPC分类号： A61B8/14

CPC分类号： A61B8/4461 ,  A61B5/0066 ,  A61B5/02007 ,  A61B8/12 ,  A61B8/145 ,  A61B8/445 ,  A61B8/4483 ,  A61B2090/3614 ,  A61B2090/3784 ,  A61M25/0138 ,  A61M25/0158 ,  F16C2202/28 ,  G01S7/52079 ,  G01S15/8943 ,  G10K11/004

摘要： The present invention relates to a new intravascular imaging device based on a Shape Memory Alloy (SMA) actuator mechanism embedded inside an elongate member such as a guide wire or catheter. The present invention utilizes a novel SMA mechanism to provide side-looking imaging by providing movement for an ultrasound transducer element. This novel SMA actuator mechanism can be easily fabricated in micro-scale, providing an advantage over existing imaging devices because it offers the ability to miniaturize the overall size of the device, while the use of multiple transducer crystals maximizes field of view. Also disclosed are methods of using the same.

摘要翻译： 本发明涉及一种基于形状记忆合金（SMA）致动器机构的新的血管内成像装置，其嵌入诸如导丝或导管的细长构件内部。 本发明利用一种新颖的SMA机制来提供超声换能器元件的移动来提供侧视成像。 这种新颖的SMA致动器机构可以容易地以微尺度制造，提供了优于现有成像装置的优点，因为它提供了使装置的整体尺寸小型化的能力，而多个换能器晶体的使用使视野最大化。 还公开了使用该方法的方法。

公开(公告)号：US20110218437A1

公开(公告)日：2011-09-08

申请号：US12877560

申请日：2010-09-08

申请人： Byong-Ho Park ,  Oren Levy ,  Frank Hubbard

发明人： Byong-Ho Park ,  Oren Levy ,  Frank Hubbard

IPC分类号： A61B8/14

CPC分类号： A61B8/4461 ,  A61B8/085 ,  A61B8/0883 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4466 ,  A61B8/587

摘要： Devices, systems, and methods for controlling the field of view in imaging systems are provided. For example, in one embodiment an imaging system includes a flexible elongate sized and shaped for use within an internal structure of a patient, an imaging transducer positioned within the distal portion of the flexible elongate member, and a monitor positioned within the distal portion of the flexible elongated member and configured to generate a feedback signal indicative of a position of the imaging transducer relative to the transducer's motion profile. The imaging system may also include a controller in communication with the monitor and configured to adjust a control signal based on the feedback signal in order to achieve a desired field of view for the imaging transducer.

摘要翻译： 提供了用于控制成像系统中的视野的设备，系统和方法。 例如，在一个实施例中，成像系统包括尺寸和形状适于在患者的内部结构内使用的柔性细长件，位于柔性细长构件的远端部分内的成像传感器和位于 柔性细长构件并且被配置为产生指示成像换能器相对于换能器的运动曲线的位置的反馈信号。 成像系统还可以包括与监视器通信并被配置为基于反馈信号调整控制信号的控制器，以便实现成像换能器的期望视场。