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    Sensors and control for an interventional catheter
    1.
    发明申请
    Sensors and control for an interventional catheter 有权
    介入导管的传感器和控制

    公开(公告)号：US20090099551A1

    公开(公告)日：2009-04-16

    申请号：US12151963

    申请日：2008-05-09

    申请人： Alexander Tung ,  Gunter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

    发明人： Alexander Tung ,  Gunter Niemeyer ,  David Liang ,  Byong-Ho Park ,  Friedrich B. Prinz ,  Bob S. Hu

    IPC分类号： A61M25/00

    CPC分类号： A61B5/103 ,  A61B5/6852 ,  A61B5/6885 ,  A61B5/7455 ,  A61B2034/2061 ,  A61B2562/0252 ,  A61B2562/0261 ,  A61B2562/0266 ,  A61B2562/043

    摘要： This invention provides small position sensors for applications where localized sensing in a small volume of space is needed but where measurement of large relative displacement is also necessary. The invention enables a surgeon to accurately position the tip of a catheter during minimally invasive therapy. The current invention further improves the quality of tactile feedback to a physician during catheter-based surgeries with an axial force sensor at the tip of the catheter that allows for the transmission of force information to the physician. One embodiment of this invention is a position sensor for active interventional catheters, where the sensor may be laser-machined shape memory alloy (SMA), and the catheter actuators may be heated SMA or wire-pulleys. Providing position feedback from a catheter during minimally invasive therapy allows for closed-loop control of the catheter tip position under computer-aided guidance and enable force feedback to the physician.

    摘要翻译： 本发明提供小型位置传感器，用于需要在小体积空间中进行局部感测但也需要测量大的相对位移的应用。 本发明使得外科医生能够在微创治疗期间精确地定位导管的尖端。 本发明进一步提高了在基于导管的手术过程中对医生的触觉反馈的质量，其中导管的尖端处的轴向力传感器允许向医师传递力信息。 本发明的一个实施例是用于主动介入导管的位置传感器，其中传感器可以是激光加工的形状记忆合金（SMA），并且导管致动器可以被加热SMA或线滑轮。 在微创治疗期间从导管提供位置反馈允许在计算机辅助引导下对导管尖端位置进行闭环控制，并使能力反馈给医师。

    Tubular compliant shape memory alloy actuators
    3.
    发明申请
    Tubular compliant shape memory alloy actuators 审中-公开
    管状符合形状记忆合金执行器

    公开(公告)号：US20070037445A1

    公开(公告)日：2007-02-15

    申请号：US11487152

    申请日：2006-07-13

    申请人： Byong-Ho Park ,  David Liang

    发明人： Byong-Ho Park ,  David Liang

    IPC分类号： H01R9/05

    CPC分类号： F03G7/065 ,  A61M25/0105 ,  H01R4/01 ,  H01R13/5224

    摘要： A shape memory alloy (SMA) actuator made from tubular structures is disclosed. The current invention is a tubular monolithic SMA actuator made from a tubular monolithic SMA substrate of NiTi, CuAlNi, CuAl, CuZnAl, TiV, or TiNb. The tubular monolithic SMA actuator has a first end, a second end and a middle portion, and can be made out or a substrate with a cross-section shape such as a circle, an ellipse, a rectangle or any irregular shape. The middle portion is formed into an actuator pattern that maintains unity and electrical continuity, along the path of the actuator pattern, with the first end and second end. The actuator pattern can be any number of patterns, for example, a Greek key pattern or a zigzag pattern. A first electrode is optionally formed in the first end and a second electrode is formed in the second end of the tubular monolithic SMA actuator.

    摘要翻译： 公开了一种由管状结构制成的形状记忆合金（SMA）致动器。 本发明是由NiTi，CuAlNi，CuAl，CuZnAl，TiV或TiNb的管状单片SMA基片制成的管状单片SMA致动器。 管状单片SMA致动器具有第一端，第二端和中间部分，并且可以制成具有诸如圆形，椭圆形，矩形或任何不规则形状的横截面形状的基板。 中间部分形成为致动器图案，其沿着致动器图案的路径与第一端和第二端保持单一和电连续性。 致动器图案可以是任何数量的图案，例如，希腊键图案或之字形图案。 第一电极任选地形成在第一端中，并且第二电极形成在管状单片SMA致动器的第二端中。

    T-statistic method for suppressing artifacts in blood vessel ultrasonic imaging
    5.
    发明申请
    T-statistic method for suppressing artifacts in blood vessel ultrasonic imaging 审中-公开
    用于抑制血管超声成像中伪像的T统计方法

    公开(公告)号：US20060030777A1

    公开(公告)日：2006-02-09

    申请号：US11191311

    申请日：2005-07-28

    申请人： David Liang ,  Phillip Yang ,  Aditya Koolwal ,  Byong-Ho Park

    发明人： David Liang ,  Phillip Yang ,  Aditya Koolwal ,  Byong-Ho Park

    IPC分类号： A61B8/00

    CPC分类号： A61B8/12 ,  G06T5/008 ,  G06T5/50 ,  G06T7/0012 ,  G06T2207/10132 ,  G06T2207/30101

    摘要： A technique for enhancing the image quality in intravascular ultrasound imaging increases contrast between blood and vessel wall processes image data using a point-wise t-statistic technique. Data from an ultrasound transducer is digitized and stored in a memory buffer [500]. For each point in the image, a t-statistic value is derived from signal amplitude values for the same point at a sequence of previous frames [502]. An image is then generated and displayed using the t-statistic values for the intensity of each point [504]. The improvement in contrast ratio as compared to averaging techniques is most significant at highly oblique angles when contrast ratio is particularly poor in the unprocessed signal.

    摘要翻译： 一种增强血管内超声成像图像质量的技术增加血液和血管壁之间的对比，使用点式t统计技术对图像数据进行对比。 来自超声换能器的数据被数字化并存储在存储器缓冲器[500]中。 对于图像中的每个点，从先前帧序列的相同点的信号振幅值导出t统计值[502]。 然后使用每个点的强度的t统计值来生成和显示图像[504]。 与平均化技术相比，对比度的改善在高度倾斜的角度是最显着的，当未处理信号的对比度比特别差时。

    Method and apparatus for sterilizing medical and laboratory instruments and devices
    8.
    发明申请
    Method and apparatus for sterilizing medical and laboratory instruments and devices 有权
    用于对医疗和实验室仪器和设备进行消毒的方法和设备

    公开(公告)号：US20070172384A1

    公开(公告)日：2007-07-26

    申请号：US10558102

    申请日：2003-05-22

    申请人： David Liang ,  Joo Tay ,  Tuti Lim ,  Dong Li

    发明人： David Liang ,  Joo Tay ,  Tuti Lim ,  Dong Li

    IPC分类号： A61L2/04 ,  A61L2/18

    CPC分类号： F23D14/56 ,  A61L2/04 ,  A61L2/202 ,  A61L2/208 ,  A61L2202/24 ,  F23D14/20 ,  F23D14/32 ,  F23D91/02

    摘要： A method for sterilizing medical devices, comprising the steps: producing a plurality of hydrogen surface-mixed diffusion flame; exposing the plurality of hydrogen surface-mixed diffusion flame to the medical devices for a predetermined period of time; and exposing the medical devices to the plurality of hydrogen surface-mixed diffusion flame at a predetermined distance; wherein the hydrogen surface mixed diffusion flame further produces free radicals for further sterilizing of the medical devices.

    摘要翻译： 一种灭菌医疗装置的方法，其特征在于，包括以下步骤：制造多个氢表​​面混合扩散火焰; 将多个氢表面混合扩散火焰暴露于医疗装置一段预定的时间; 以及将所述医疗装置以预定距离暴露于所述多个氢表面混合扩散火焰; 其中氢表面混合扩散火焰进一步产生自由基以进一步消毒医疗器械。

    High intensity focused ultrasound for imaging and treatment of arrhythmias
    9.
    发明申请
    High intensity focused ultrasound for imaging and treatment of arrhythmias 审中-公开
    高强度聚焦超声成像和治疗心律失常

    公开(公告)号：US20050267453A1

    公开(公告)日：2005-12-01

    申请号：US11137961

    申请日：2005-05-25

    申请人： Serena Wong ,  David Liang ,  Girish Narayan

    发明人： Serena Wong ,  David Liang ,  Girish Narayan

    IPC分类号： A61B8/00 ,  A61B8/12 ,  A61B17/00 ,  A61B18/04 ,  A61B19/00 ,  A61N7/02

    CPC分类号： A61B8/4488 ,  A61B8/12 ,  A61B8/445 ,  A61B8/543 ,  A61B2017/00243 ,  A61B2090/3782 ,  A61N7/022

    摘要： A dual-mode, capable of imaging and ablation, ultrasound array integrated in a catheter is provided for minimally invasive treatment of arrhythmias. The catheter array is small enough for insertion through a peripheral vein and is longitudinally integrated with the catheter to have a side-view for tissue imaging and ablation. A high length/width array ratio creates a large aperture necessary for high power ablation densities. A catheter stabilization device maintains a distance between the catheter array and the wall of a heart or vein. Visualization of anatomy and imaging of ablated tissue provides a guide for placing the lesion and assists in achieving a pattern of ablated tissue. The catheter is advanced to another area by catheter rotation and/or array steering or focusing. Gating the imaging and ablation processes to a heart cycle allows for accounting and compensation of heart motion and enables automation of an arrhythmia treatment.

    摘要翻译： 提供集成在导管中的能够成像和消融的双模，用于微创治疗心律失常。 导管阵列足够小以插入通过外周静脉，并且与导管纵向一体化以具有用于组织成像和消融的侧视图。 高长度/宽度的阵列比率产生大功率消融密度所需的大孔径。 导管稳定装置保持导管阵列与心脏或静脉壁之间的距离。 消融组织的解剖学和成像的可视化提供了放置病变的指导并且帮助实现消融组织的图案。 导管通过导管旋转和/或阵列转向或聚焦而前进到另一个区域。 将成像和消融过程门控到心脏周期允许心脏运动的记帐和补偿，并实现心律失常治疗的自动化。

    Combination of utensils
    10.
    发明授权
    Combination of utensils 失效
    器具组合

    公开(公告)号：US5363755A

    公开(公告)日：1994-11-15

    申请号：US235389

    申请日：1994-04-29

    申请人： David Liang

    发明人： David Liang

    IPC分类号： A47B77/02 ,  B02C19/20 ,  A41J43/25

    CPC分类号： A47B77/02

    摘要： A combination of utensils including a table defining an upperside and an underside. The upperside of the table defines a first recess, a second recess, a cutout being in communication with the first and second recesses, a third recess and two shaft-receiving recesses each defining a narrow entry. The table defines an aperture within the second recess. A chopping board is receivable in the first recess. A mandolin/grater is receivable in the second recess. A sharpening wheel is formed on a shaft. The sharpening wheel is pivotably receivable in the third recess as two ends of the shaft are retained in the shaft-receiving recesses. Two first flanges are formed on the underside of the table. A tool-receiving box includes two flanges formed thereon. The flanges of the tool-receiving box are engageable with the first flanges of the table so that the tool-receiving box is slidably mounted on the underside of the table. Two second flanges are formed on the underside of the table. A food-receiving box includes two flanges formed thereon. The flanges of the food-receiving box are engageable with the second flanges of the table so that the food-receiving box is slidably mounted on the underside of the table.

    摘要翻译： 餐具的组合，包括定义上侧和下侧的桌子。 桌子的上侧限定了第一凹部，第二凹部，与第一凹部和第二凹部连通的切口，第三凹部和两个轴接收凹部，每个限定狭窄的入口。 桌子在第二凹槽内限定一个孔。 砧板在第一个休息区应收。 曼陀林/磨床在第二个休息区应收。 在轴上形成磨刀轮。 当轴的两端保持在轴接收凹部中时，锐化轮可枢转地接收在第三凹部中。 在桌子的下侧形成两个第一凸缘。 工具接收箱包括形成在其上的两个凸缘。 工具接收箱的凸缘可与工作台的第一凸缘接合，使得工具接收盒可滑动地安装在工作台的下侧上。 在桌子的下侧形成两个第二凸缘。 食物接收箱包括形成在其上的两个凸缘。 食物接收盒的凸缘可与桌子的第二凸缘接合，使得食物接收盒可滑动地安装在餐桌的下侧。