公开(公告)号：US11053525B2

公开(公告)日：2021-07-06

申请号：US15739699

申请日：2016-03-29

Applicant: CJ Cheiljedang Corporation

Inventor： Hee Kyoung Jung ,  Hye Won Um ,  Hong Xian Li ,  Su Jin Park ,  Young Lyeol Yang ,  Kyoung Min Lee ,  Hyo Hyoung Lee

IPC: C12N1/20 ,  C12P13/00 ,  C12P13/10 ,  C12N9/10 ,  C12N9/88

Abstract: The present invention relates to a recombinant microorganism for producing putrescine or ornithine, and a method for producing putrescine or ornithine using the same. Specifically, the present invention relates to a microorganism of the genus Corynebacterium capable of producing putrescine or ornithine, in which an activity of the transcriptional regulator of sugar metabolism (SugR) is weakened, an activity of the citrate synthase (GltA) is enhanced, or both are applied; and a method for producing putrescine or ornithine using the same.

公开(公告)号：US10801047B2

公开(公告)日：2020-10-13

申请号：US16632084

申请日：2018-07-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyoung Min Lee ,  Sung Gun Lee ,  Seon Hye Kim ,  Kyungsu Na ,  Hong Xian Li ,  Hyun-jung Bae ,  Young Lyeol Yang ,  Hye Won Um ,  Hyo Hyoung Lee

IPC: C12P13/00

Abstract: The present disclosure relates to a putrescine-producing microorganism of the genus Corynebacterium, and a method of producing putrescine using the same.

公开(公告)号：US11053524B2

公开(公告)日：2021-07-06

申请号：US16246082

申请日：2019-01-11

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyoung Min Lee ,  Hee Kyoung Jung ,  Young Lyeol Yang ,  Hye Won Um ,  Chang Gyeom Kim ,  Hong Xian Li ,  Su Jin Park ,  Jong Hyun Yoon ,  Baek Seok Lee ,  Sun Young Lee

IPC: C12P13/00 ,  C12N9/88 ,  C12N9/10 ,  C12N9/02 ,  C12N9/12 ,  C12N1/21 ,  C12N15/52

Abstract: The present invention relates to a recombinant microorganism capable of producing putrescine, in which the microorganism is modified to have enhanced NCgl2522 activity, thereby producing putrescine in a high yield, and a method for producing putrescine using the microorganism.

公开(公告)号：US20140363859A1

公开(公告)日：2014-12-11

申请号：US14373265

申请日：2013-01-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyoung Min Lee ,  Seon Hye Kim ,  Hye Won Um ,  Min Sun Kang ,  Su Jin Choi ,  Hee Kyoung Jung ,  Sung Hoo Jhon ,  Hongxian Li ,  Won Sik Gwak ,  Chong Ho Lee ,  Young Lyeol Yang

IPC: C12N15/77 ,  C12P13/00

CPC classification number: C12N15/77 ,  C12N15/52 ,  C12P13/001

Abstract: The present invention relates to a recombinant microorganism having enhanced ability to produce putrescine at high yield, wherein the activity of NCgl0101 is weakened in a microorganism of genus Corynebacterium that has been modified to produce putrescine, and a method for producing putrescine using the same.

Abstract translation: 本发明涉及一种能够以高产率产生腐胺的能力增强的重组微生物，其中在已经被修饰以产生腐胺的棒状杆菌属的微生物中，NCgl0101的活性被削弱，以及使用其的腐胺的制备方法。

公开(公告)号：US10450262B2

公开(公告)日：2019-10-22

申请号：US15572381

申请日：2016-05-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Won Sik Gwak ,  Hong Xian Li ,  Hyun Ju Won ,  Hyo Hyoung Lee ,  Kyung Su Na ,  Su Jin Park ,  Young Lyeol Yang ,  Hye Won Um ,  Chang Yub Oh ,  Kyoung Min Lee

IPC: C07C209/86 ,  C07C211/09 ,  B01D3/14 ,  C07C209/84 ,  C12P13/00

Abstract: A method for purifying 1,4-diaminobutane comprising the steps of: separating a second composition including carbonate salt of 1,4-diaminobutane from a first composition including carbonate salt of 1,4-diaminobutane by distillation; and removing carbonate from carbonate salt of 1,4-diaminobutane included in the second composition to recover 1,4-diaminobutane.

公开(公告)号：US20190119709A1

公开(公告)日：2019-04-25

申请号：US16240049

申请日：2019-01-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyoung Min Lee ,  Su Jin Park ,  Hee Kyoung Jung ,  Young Lyeol Yang ,  Hong Xian Li ,  Hye Won Um

IPC: C12P13/00 ,  C07K14/34 ,  C12N15/70 ,  C12N15/77 ,  C07K14/195

Abstract: The present invention relates to a microorganism for producing diamine, in which activity of a protein having an amino acid sequence of SEQ ID NO: 6 or an amino acid sequence having 55% or higher sequence homology with SEQ ID NO: 6 is introduced or enhanced, and a method of producing diamine using the same.

公开(公告)号：US20150104838A1

公开(公告)日：2015-04-16

申请号：US14372000

申请日：2013-01-11

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Su Jin Choi ,  Hyang Choi ,  Min Sun Kang ,  Sung Hoo Jhon ,  Kyoung Min Lee ,  Hye Won Um ,  Young Lyeol Yang

IPC: C12P13/00

CPC classification number: C12P13/001 ,  C12N9/1029 ,  C12N15/1093

Abstract: The present invention relates to a recombinant microorganism having enhanced ability of producing putrescine at high yield, which is generated by weakening the activity of NCgl1469 in a microorganism of Corynebacterium genus that is modified to produce putrescine, and a method for producing putrescine using the same.

Abstract translation: 本发明涉及通过削弱经修饰以产生腐胺的棒状杆菌属微生物中的NCgl1469的活性而产生的以高产率产生腐胺的能力增强的重组微生物，以及使用其制造腐胺的方法。

公开(公告)号：US11365400B2

公开(公告)日：2022-06-21

申请号：US17074203

申请日：2020-10-19

Applicant: CJ Cheiljedang Corporation

Inventor： Su Jin Park ,  Young Lyeol Yang ,  Hye Won Um ,  Hong Xian Li ,  Kyoung Min Lee ,  Baek Seok Lee ,  Hyo Hyoung Lee ,  Hee Kyoung Jung

IPC: C12N9/10 ,  C12N9/80 ,  C12P13/00 ,  C12N15/52 ,  C12N1/00 ,  C12N15/00 ,  C12N9/12 ,  C12N9/88 ,  C12N9/00 ,  C12P13/10

Abstract: Disclosed is a modified microorganism producing putrescine or ornithine, and a method for producing putrescine or ornithine using the same.

公开(公告)号：US09290771B2

公开(公告)日：2016-03-22

申请号：US14373265

申请日：2013-01-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Kyoung Min Lee ,  Seon Hye Kim ,  Hye Won Um ,  Min Sun Kang ,  Su Jin Choi ,  Hee Kyoung Jung ,  Sung Hoo Jhon ,  Hongxian Li ,  Won Sik Gwak ,  Chong Ho Lee ,  Young Lyeol Yang

IPC: C12N15/77 ,  C12N15/52 ,  C12P13/00

CPC classification number: C12N15/77 ,  C12N15/52 ,  C12P13/001

Abstract: The present invention relates to a recombinant microorganism having enhanced ability to produce putrescine at high yield, wherein the activity of NCg10101 is weakened in a microorganism of genus Corynebacterium that has been modified to produce putrescine, and a method for producing putrescine using the same.

Abstract translation: 本发明涉及一种能够以高产率产生腐胺的能力增强的重组微生物，其中NCg10101的活性在经过改良以产生腐胺的棒状杆菌属的微生物中被削弱，以及使用其的腐胺的制备方法。

公开(公告)号：US20230392174A1

公开(公告)日：2023-12-07

申请号：US18021059

申请日：2021-03-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jaehun Lee ,  Kyoung Min Lee ,  Hyun-jung Bae

IPC: C12P13/00 ,  C12N9/10 ,  C12N9/80 ,  C12N15/77 ,  C12N15/52

CPC classification number: C12P13/002 ,  C12N9/1029 ,  C12Y203/01001 ,  C12N9/80 ,  C12Y305/01016 ,  C12N15/77 ,  C12N15/52 ,  C12N2800/101

Abstract: The present invention relates to a microorganism for producing putrescine and a method for producing putrescine by using same.