公开(公告)号：US20190351197A9

公开(公告)日：2019-11-21

申请号：US15810721

申请日：2017-11-13

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61M25/10 ,  A61L29/08 ,  A61F2/844 ,  A61F2/958 ,  A61L27/54 ,  A61F2/82 ,  A61L29/16 ,  A61L31/16

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

公开(公告)号：US09814865B2

公开(公告)日：2017-11-14

申请号：US14193312

申请日：2014-02-28

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61M25/10 ,  B05D3/02 ,  A61M31/00 ,  A61F2/82 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  A61F2/844 ,  A61F2/958 ,  A61L29/08

CPC分类号： A61M25/10 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/958 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0025 ,  A61F2250/0026 ,  A61F2250/0067 ,  A61F2250/0081 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61L27/54 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61L29/18 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2250/00

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

公开(公告)号：US20170105858A1

公开(公告)日：2017-04-20

申请号：US15381291

申请日：2016-12-16

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61F2/958 ,  A61L31/14 ,  A61L29/18 ,  A61L29/08 ,  A61M25/10 ,  A61L29/16

CPC分类号： A61M25/10 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/958 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0025 ,  A61F2250/0026 ,  A61F2250/0067 ,  A61F2250/0081 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61L27/54 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61L29/18 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2250/00

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

公开(公告)号：US20160271373A1

公开(公告)日：2016-09-22

申请号：US15166486

申请日：2016-05-27

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61M25/10 ,  A61L29/16 ,  A61F2/82 ,  A61L29/08 ,  A61F2/844 ,  A61F2/958

CPC分类号： A61M25/10 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/958 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0025 ,  A61F2250/0026 ,  A61F2250/0067 ,  A61F2250/0081 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61L27/54 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61L29/18 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2250/00

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

公开(公告)号：US20150119633A1

公开(公告)日：2015-04-30

申请号：US14568448

申请日：2014-12-12

申请人： COOK MEDICAL TECHNOLOGIES LLC

发明人： Kenneth Haselby ,  Brian D. Choules ,  Blayne A. Roeder ,  Richard B. Sisken ,  David Eric Orr ,  James D. Purdy ,  Steven J. Charlebois ,  David D. Grewe ,  Neal E. Fearnot ,  Alan R. Leewood

IPC分类号： A61M1/12

CPC分类号： A61M1/125 ,  A61B5/076 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/6862 ,  A61B5/6876 ,  A61B5/6882 ,  A61F2/0077 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2/86 ,  A61F2002/068 ,  A61F2002/8486 ,  A61F2220/0016 ,  A61F2220/0058 ,  A61F2220/0075 ,  A61F2230/005 ,  A61F2230/0071 ,  A61F2230/008 ,  A61M1/1006 ,  A61M1/1008 ,  A61M1/101 ,  A61M1/1098 ,  A61M1/122 ,  A61M1/3653 ,  A61M1/3659

摘要： A method of attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes an intravascular device and biological attachment material connected to the intravascular device. The biological attachment material is configured to attach the intravascular device to the vessel wall.

摘要翻译： 公开了一种将血管内装置附接到身体血管的血管壁的方法。 附件系统包括连接到血管内装置的血管内装置和生物附着材料。 生物附着材料构造成将血管内装置附接到血管壁。

公开(公告)号：US20180064916A1

公开(公告)日：2018-03-08

申请号：US15810721

申请日：2017-11-13

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61M25/10 ,  A61L29/08 ,  A61F2/844 ,  A61F2/958 ,  A61L27/54 ,  A61F2/82 ,  A61L29/16 ,  A61L31/16

CPC分类号： A61M25/10 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/958 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0025 ,  A61F2250/0026 ,  A61F2250/0067 ,  A61F2250/0081 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61L27/54 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61L29/18 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2250/00

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

公开(公告)号：US20140178563A1

公开(公告)日：2014-06-26

申请号：US14193312

申请日：2014-02-28

申请人： Cook Medical Technologies LLC

发明人： Brian L. Bates ,  Anthony O. Ragheb ,  Joseph M. Stewart, IV ,  William J. Bourdeau ,  Brian D. Choules ,  James D. Purdy ,  Neal E. Fearnot

IPC分类号： A61M25/10

CPC分类号： A61M25/10 ,  A61F2/82 ,  A61F2/844 ,  A61F2/86 ,  A61F2/958 ,  A61F2210/0014 ,  A61F2210/0076 ,  A61F2240/001 ,  A61F2250/0025 ,  A61F2250/0026 ,  A61F2250/0067 ,  A61F2250/0081 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61L27/54 ,  A61L29/08 ,  A61L29/085 ,  A61L29/16 ,  A61L29/18 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/06 ,  A61M25/1029 ,  A61M25/104 ,  A61M2025/1031 ,  A61M2025/105 ,  A61M2250/00

摘要： A coated medical device (10) including a structure (12) adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material (14) having a bioactive material layer (18) disposed thereon. The medical device is preferably an implantable stent or balloon (26) of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material (58) positioned between the base and bioactive material layers of the balloon.

摘要翻译： 一种涂覆的医疗装置（10），包括适于引入患者的通道或容器中的结构（12）。 该结构优选由其上设置有生物活性材料层（18）的无孔基材（14）形成。 该医疗装置优选为其上沉积有生物活性物质层的可植入支架或球囊（26）。 支架可以围绕气囊定位，另一层生物活性材料放置在整个结构上并延伸超过定位的支架的端部。 气囊的端部延伸超过支架的端部并且包括其上的生物活性材料，用于将生物活性材料输送到与其接触的血管壁的细胞。 气囊还包括位于气囊的基部和生物活性材料层之间的一层亲水材料（58）。