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公开(公告)号：US20140188250A1
公开(公告)日：2014-07-03
申请号：US14088606
申请日：2013-11-25
发明人： Neal E. Fearnot , Michael C. Hiles , Jeremy Metz , F. Joseph Obermiller , Andrew J. Kaucher , Steven Charlebois
IPC分类号： A61F2/01
CPC分类号： A61L27/60 , A61F2/0063 , A61F2/02 , A61F2002/0072 , A61F2210/0076 , A61F2250/0003 , A61F2250/0068 , A61L27/3633 , A61L27/38
摘要： Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. Also described are methods for making and using these medical graft materials and devices.
摘要翻译： 描述了可以用液体添加剂如细胞悬浮液，生物活性剂或它们的组合有效地改性的医用移植材料和装置。 还描述了制造和使用这些医用移植材料和装置的方法。
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公开(公告)号：US09931439B2
公开(公告)日：2018-04-03
申请号：US14088606
申请日：2013-11-25
发明人： Neal E. Fearnot , Michael C. Hiles , Jeremy Metz , F. Joseph Obermiller , Andrew J. Kaucher , Steven Charlebois
CPC分类号： A61L27/60 , A61F2/0063 , A61F2/02 , A61F2002/0072 , A61F2210/0076 , A61F2250/0003 , A61F2250/0068 , A61L27/3633 , A61L27/38
摘要： Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. The medical graft materials and devices can have a first outer surface and a second outer surface and can define an internal chamber between the first outer surface and the second outer surface. The medical graft materials and devices can also have at least one region of the graft material interrupting the chamber and surrounded by the chamber. Also described are methods for making and using these medical graft materials and devices.
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公开(公告)号：US20210308342A1
公开(公告)日：2021-10-07
申请号：US17353969
申请日：2021-06-22
发明人： Rhonda Peck , Bhavin B. Shah , Umesh H. Patel , Krista Gearhart , Steven Charlebois , Keith Milner , Eric J. Rodenberg
摘要： The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
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公开(公告)号：US20140315847A1
公开(公告)日：2014-10-23
申请号：US14210903
申请日：2014-03-14
发明人： Rhonda Peck , Bhavin Shah , Umesh H. Patel , Krista Gearhart , Steven Charlebois , Keith Milner , Eric J. Rodenberg
CPC分类号： A61L31/146 , A61L27/3633 , A61L27/54 , A61L27/56 , A61L31/005 , A61L31/16 , A61L2300/406 , A61L2300/414
摘要： The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
摘要翻译： 在某些方面，本发明提供在产品中和/或上并入多个药物贮库的医用移植产品。 一种这样的产品是片状移植物构建体，例如用于组织支撑物，其包括具有多个药物贮库的片材移植材料。 药物贮库可以是直接形成在片状接枝材料上的硬化沉积物和/或能够将药物洗脱至少72小时。
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公开(公告)号：US11065368B2
公开(公告)日：2021-07-20
申请号：US14210903
申请日：2014-03-14
发明人： Rhonda Peck , Bhavin Shah , Umesh H. Patel , Krista Gearhart , Steven Charlebois , Keith Milner , Eric J. Rodenberg
摘要： The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.
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公开(公告)号：US09956384B2
公开(公告)日：2018-05-01
申请号：US14603515
申请日：2015-01-23
发明人： Steven Charlebois , Sara Sherman
CPC分类号： A61M25/1011 , A61M25/0155 , A61M25/1002 , A61M25/1025 , A61M2025/1013 , A61M2025/1045 , A61M2025/105 , A61M2025/1086 , A61M2025/1088 , A61M2025/1093
摘要： Articulating balloon catheters and methods of using articulating balloon catheters are described herein. An embodiment of an articulating balloon catheter comprises an elongate member and a balloon. The balloon is attached to the elongate member and is adapted to move between a deflated configuration and an inflated configuration. The balloon has a proximal portion, a distal portion, and an articulating region disposed between the proximal portion and the distal portion. The articulating region of the balloon is configured to provide articulation between the proximal portion and the distal portion of the balloon.
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公开(公告)号：US20170007754A1
公开(公告)日：2017-01-12
申请号：US14791712
申请日：2015-07-06
发明人： Charles F. Babbs , Steven Charlebois , Kenneth Haselby , Jarin Kratzberg , Justin Metcalf , Richard B. Sisken
CPC分类号： A61M1/1006 , A61F2002/8483 , A61M1/1008 , A61M1/106 , A61M1/107 , A61M1/1072 , A61M1/1086 , A61M1/1096 , A61M1/125
摘要： An endovascular assembly for improving vessel compliance by reducing the blood pressure needed to eject a given volume of blood. The assembly comprises a first expandable container, a balloon for example, positioned in the vascular system. The first container has a variable volume in response to blood flow in the vessel, and is fixed to at least one expandable attachment member. When the attachment member is expanded inside of the vasculature, the attachment member is preferably fixed inside the vessel. The assembly further comprises a second container, preferably having a fixed volume that forms a closed fluid system when fluidly connected to the first container. The connection between the first and second container permits a change in volume in the first container to flow fluid into the second container. The second container can be placed in a different location inside of the patient, preferably outside of the vessel.
摘要翻译： 用于通过降低喷射给定体积的血液所需的血压来改善血管依从性的血管内装置。 该组件包括位于血管系统中的第一可膨胀容器，例如球囊。 第一容器响应于容器中的血流而具有可变体积，并且固定到至少一个可扩张的附接构件。 当附着构件在脉管系统的内部扩张时，优选地，固定构件固定在容器的内部。 组件还包括第二容器，优选地具有固定容积，当流体连接到第一容器时形成封闭的流体系统。 第一和第二容器之间的连接允许在第一容器中的体积变化以将流体流入第二容器。 第二容器可以放置在患者体内的不同位置，优选地位于血管外。
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公开(公告)号：US09149585B2
公开(公告)日：2015-10-06
申请号：US13866439
申请日：2013-04-19
发明人： Jennifer Rodenberg , William Bourdeau , Charles Baxter , Steven Charlebois , Zach Wagner , Sara Sherman
CPC分类号： A61M5/3295 , A61M25/0084 , A61M25/0097 , A61M2025/0008 , A61M2025/0086 , A61M2025/0087
摘要： A medical device and a method of treating stress urinary incontinence are provided. The device includes a cannula with a plurality of apertures. A plurality of needles is disposed within a lumen of the cannula. A handle includes a housing and a shifter mechanism to translate the plurality of needles from a first position in which the needles are disposed within the lumen of the cannula, to a second position in which a distal portion of each needle extends out of the lumen through respective apertures. The handle also includes a slot including a transversal track defining a potential range of rotational motion of the shifter mechanism with respect to the housing, and a plurality of longitudinal tracks defining a potential range of translational motion of the shifter mechanism with respect to the housing. The shifter mechanism may also rotate the cannula with respect to the handle.
摘要翻译： 提供了一种医疗装置和治疗压力性尿失禁的方法。 该装置包括具有多个孔的套管。 多个针布置在套管的内腔内。 手柄包括壳体和换档器机构，用于将多个针从其中布置在套管内腔中的第一位置平移到第二位置，在第二位置，每个针的远端部分延伸出管腔通过 各孔。 手柄还包括一个槽，该槽包括限定换挡机构相对于壳体的旋转运动的潜在范围的横向轨道，以及多个纵向轨道，其限定换挡器机构相对于壳体的平移运动的潜在范围。 换档机构还可以相对于把手旋转套管。
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公开(公告)号：US20150209483A1
公开(公告)日：2015-07-30
申请号：US14683486
申请日：2015-04-10
CPC分类号： A61L31/08 , A61F2/82 , A61F2210/0004 , A61F2210/0076 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61L2420/02
摘要： One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.
摘要翻译： 一个方面提供了包括具有表面并且在表面的至少一部分上具有涂层的生物可吸收结构的可植入医疗装置。 在某些实施方案中，涂层包括可释放的生物活性物质，并且在植入人或兽医患者体内时提供对生物可吸收结构的受控吸收。 另一方面提供了治疗疾病的方法，包括将这种装置植入人或兽医患者的血管。
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公开(公告)号：US20140180398A1
公开(公告)日：2014-06-26
申请号：US13788056
申请日：2013-03-07
IPC分类号： A61F2/82
CPC分类号： A61L31/08 , A61F2/82 , A61F2210/0004 , A61F2210/0076 , A61L31/022 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2300/62 , A61L2420/02
摘要： One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient.
摘要翻译： 一个方面提供了包括具有表面并且在表面的至少一部分上具有涂层的生物可吸收结构的可植入医疗装置。 在某些实施方案中，涂层包括可释放的生物活性物质，并且在植入人或兽医患者体内时提供对生物可吸收结构的受控吸收。 另一方面提供了治疗疾病的方法，包括将这种装置植入人或兽医患者的血管。
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