公开(公告)号：US20180206747A1

公开(公告)日：2018-07-26

申请号：US15826559

申请日：2017-11-29

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Niema Pahlevan ,  Peyman Tavallali ,  Morteza Gharib

IPC: A61B5/024 ,  A61B7/04 ,  A61B5/02 ,  A61B5/026 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/00 ,  A61B7/02 ,  A61B5/021 ,  A61B5/0285

CPC classification number: A61B5/02427 ,  A61B5/0002 ,  A61B5/0059 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0261 ,  A61B5/0285 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/6822 ,  A61B5/6898 ,  A61B5/725 ,  A61B5/7275 ,  A61B5/742 ,  A61B7/02 ,  A61B7/04 ,  A61B2560/0431

Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.

公开(公告)号：US20210386309A1

公开(公告)日：2021-12-16

申请号：US17147728

申请日：2021-01-13

Applicant: California Institute of Technology

Inventor： Derek Rinderknecht ,  Niema M. Pahlevan ,  Peyman Tavallali ,  Morteza Gharib

IPC: A61B5/024 ,  A61B5/026 ,  A61B5/25 ,  A61B5/318 ,  A61B5/02 ,  A61B5/00 ,  A61B7/04 ,  A61B7/02

Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.

公开(公告)号：US10918291B2

公开(公告)日：2021-02-16

申请号：US15826559

申请日：2017-11-29

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Niema Pahlevan ,  Peyman Tavallali ,  Morteza Gharib

IPC: A61B5/024 ,  A61B5/0408 ,  A61B5/026 ,  A61B5/0402 ,  A61B5/02 ,  A61B5/00 ,  A61B7/04 ,  A61B7/02 ,  A61B5/0285 ,  A61B5/021

Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.

公开(公告)号：US20170020414A1

公开(公告)日：2017-01-26

申请号：US15279246

申请日：2016-09-28

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Niema Pahlevan ,  Peyman Tavallali ,  Derek Rinderknecht ,  Morteza Gharib

IPC: A61B5/11 ,  A61B5/029 ,  A61B8/08 ,  A61B8/06 ,  A61B5/021 ,  A61B5/00 ,  A61B5/02 ,  A61B5/026

CPC classification number: A61B5/1128 ,  A61B5/0004 ,  A61B5/0013 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/0261 ,  A61B5/029 ,  A61B5/1102 ,  A61B5/7235 ,  A61B5/7278 ,  A61B5/7282 ,  A61B8/065 ,  A61B8/5223 ,  A61B2562/0228

Abstract: Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.

Abstract translation: 硬件和软件方法被描述为非侵入性地监测心脏健康。 分析针对受试者各种获得的血流动力学波形，以计算或近似跨越Dicrotic Notch的两个域中的两个域中的固有频率。 与相关的切口定时一起，可以确定心率和血压值左心室射血分数和/或冲程体积。

公开(公告)号：US09480406B2

公开(公告)日：2016-11-01

申请号：US14517702

申请日：2014-10-17

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Niema Pahlevan ,  Peyman Tavallali ,  Derek Rinderknecht ,  Morteza Gharib

IPC: A61B5/05 ,  A61B5/024 ,  A61B8/02 ,  A61B8/08 ,  A61B5/029 ,  A61B5/00 ,  A61B8/06 ,  A61B5/02

CPC classification number: A61B5/1128 ,  A61B5/0004 ,  A61B5/0013 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/0261 ,  A61B5/029 ,  A61B5/1102 ,  A61B5/7235 ,  A61B5/7278 ,  A61B5/7282 ,  A61B8/065 ,  A61B8/5223 ,  A61B2562/0228

Abstract: Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.

Abstract translation: 硬件和软件方法被描述为非侵入性地监测心脏健康。 分析针对受试者各种获得的血流动力学波形，以计算或近似跨越Dicrotic Notch的两个域中的两个域中的固有频率。 与相关的切口定时一起，可以确定心率和血压值左心室射血分数和/或冲程体积。

公开(公告)号：US20150094697A1

公开(公告)日：2015-04-02

申请号：US14562579

申请日：2014-12-05

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Hesham Azizgolshani ,  Morteza Gharib

IPC: A61M5/142

CPC classification number: A61M5/14276 ,  A61M5/14224 ,  A61M37/00 ,  A61M2205/8206 ,  A61M2205/8212 ,  A61M2205/8243 ,  A61M2207/00 ,  A61M2210/0612 ,  A61M2210/0662 ,  A61M2210/0693 ,  G01F11/08

Abstract: Described herein are systems, devices, and methods for the delivery of substances to, or the sampling of substances from, a patient using a portable and preferably implantable device. The substances introduced to and/or taken from the patient are preferably fluidic and are driven by a miniature pump, such as a microimpedance pump. A number of design variations are explicitly and implicitly described, such as the use of multiple pumps and multiple reservoirs for containing medicaments. Methods of manufacture of these systems and devices are also described, for instance, using molding, micromachining, or lithographic processes.

Abstract translation: 本文描述了用于使用便携式和优选可植入装置向患者输送物质或从其中取样物质的系统，装置和方法。 引入和/或从患者取出的物质优选是流体性的，并且由微型泵例如微阻抗泵驱动。 明确和隐含地描述了许多设计变化，例如使用多个泵和多个储存器来容纳药物。 还描述了这些系统和装置的制造方法，例如使用成型，微加工或光刻工艺。

公开(公告)号：US20170020400A1

公开(公告)日：2017-01-26

申请号：US15199160

申请日：2016-06-30

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Morteza Gharib ,  Niema Pahlevan ,  Peyman Tavallali

IPC: A61B5/024 ,  A61B5/00 ,  A61B7/04

CPC classification number: A61B5/02438 ,  A61B5/02416 ,  A61B5/6822 ,  A61B5/6824 ,  A61B5/6826 ,  A61B5/6831 ,  A61B5/6833 ,  A61B7/00 ,  A61B7/04 ,  A61B2562/0204 ,  A61B2562/0223

Abstract: Devices, systems, and methods are described for acquiring heart sound timing content to enhance pulse waveform analysis.

Abstract translation: 描述了用于获取心音定时内容以增强脉搏波形分析的装置，系统和方法。

公开(公告)号：US20190167131A1

公开(公告)日：2019-06-06

申请号：US16272750

申请日：2019-02-11

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Morteza Gharib ,  Niema Pahlevan ,  Peyman Tavallali

IPC: A61B5/024 ,  A61B7/04 ,  A61B7/00

Abstract: Devices, systems, and methods are described for acquiring heart sound timing content to enhance pulse waveform analysis.

公开(公告)号：US20180020955A1

公开(公告)日：2018-01-25

申请号：US15610413

申请日：2017-05-31

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Niema Pahlevan ,  Peyman Tavallali ,  Derek Rinderknecht ,  Morteza Gharib

IPC: A61B5/11 ,  A61B8/06 ,  A61B5/00 ,  A61B5/02 ,  A61B5/026 ,  A61B5/024 ,  A61B5/021 ,  A61B8/08 ,  A61B5/029

CPC classification number: A61B5/1128 ,  A61B5/0004 ,  A61B5/0013 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/0261 ,  A61B5/029 ,  A61B5/1102 ,  A61B5/7235 ,  A61B5/7278 ,  A61B5/7282 ,  A61B8/065 ,  A61B8/5223 ,  A61B2562/0228

Abstract: Hardware and software methodology are described for non-invasively monitoring cardiac health. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. Together with associated notch timing, heart rate and blood pressure values left ventricle ejection fraction and/or stroke volume can be determination.

公开(公告)号：US20160135697A1

公开(公告)日：2016-05-19

申请号：US15006926

申请日：2016-01-26

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Derek Rinderknecht ,  Niema Pahlevan ,  Peyman Tavallali ,  Morteza Gharib

IPC: A61B5/024 ,  A61B7/02 ,  A61B5/02 ,  A61B5/00 ,  A61B5/0408

CPC classification number: A61B5/02427 ,  A61B5/0002 ,  A61B5/0059 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0261 ,  A61B5/0285 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/6822 ,  A61B5/6898 ,  A61B5/725 ,  A61B5/7275 ,  A61B5/742 ,  A61B7/02 ,  A61B7/04 ,  A61B2560/0431

Abstract: Systems and methods are provided for extracting hemodynamic information, optionally employing portable electronic devices with optional User Interface (UI) features for system implementation. The systems and methods may be employed for acquiring hemodynamic signals and associated electrophysiological data and/or analyzing the former or both in combination to yield useful physiological indicia or results. Such hardware and software is advantageously used for non-invasively monitoring cardiac health.