-
公开(公告)号：US09415193B2
公开(公告)日：2016-08-16
申请号：US13603296
申请日：2012-09-04
申请人： Carey V. Campbell , Robert L. Cleek , Daniel L. Crandall , James F. Davidson , Paul D. Drumheller , Cody L. Hartman , Theresa A. Holland , Thane L. Kranzler , Mei Li , Gregory LoStracco , Bruce M. Steinhaus , Benjamin M. Trapp , Thomas G. Triebes
发明人： Carey V. Campbell , Robert L. Cleek , Daniel L. Crandall , James F. Davidson , Paul D. Drumheller , Cody L. Hartman , Theresa A. Holland , Thane L. Kranzler , Mei Li , Gregory LoStracco , Bruce M. Steinhaus , Benjamin M. Trapp , Thomas G. Triebes
CPC分类号： A61M25/10 , A61L29/085 , A61L29/16 , A61L2300/602 , A61M2025/105 , A61M2025/1081 , F04C2270/0421
摘要： The invention is directed to eluting medical devices that enable consistent “on-demand” delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
摘要翻译： 本发明涉及洗脱能够使治疗剂向血管进行一致“按需”递送的医疗装置。 本发明的医疗装置包括可膨胀构件，亲水性涂层，其包括围绕可膨胀构件或结构层的至少一种治疗剂和具有可变可渗透微结构的外护套。 本文公开的设计和方法确保治疗剂递送基本上仅在可膨胀构件的膨胀期间发生，使涂覆和/或治疗剂对血流的损失最小化并提供受控递送至治疗部位。
-
公开(公告)号：US20120310210A1
公开(公告)日：2012-12-06
申请号：US13409843
申请日：2012-03-01
申请人： Carey V. Campbell , Robert L. Cleek , Theresa A. Holland , Thane L. Kranzler , Benjamin M. Trapp
发明人： Carey V. Campbell , Robert L. Cleek , Theresa A. Holland , Thane L. Kranzler , Benjamin M. Trapp
CPC分类号： A61M25/104 , A61F2/82 , A61F2250/0023 , A61F2250/0035 , A61F2250/0067 , A61L29/085 , A61L29/146 , A61L29/16 , A61L2300/416 , A61L2300/606 , A61M2025/09125 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1081
摘要： The invention is directed to eluting medical devices that enable consistent “on-demand” delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
摘要翻译： 本发明涉及洗脱能够使治疗剂按需递送至血管的医疗装置。 本发明的医疗装置包括可膨胀构件，亲水性涂层，其包括围绕可膨胀构件或结构层的至少一种治疗剂和具有可变可渗透微结构的外护套。 本文公开的设计和方法确保治疗剂递送基本上仅在可膨胀构件的膨胀期间发生，使涂覆和/或治疗剂对血流的损失最小化并提供受控递送至治疗部位。
-
公开(公告)号：US20130253426A1
公开(公告)日：2013-09-26
申请号：US13603296
申请日：2012-09-04
申请人： Carey V. Campbell , Robert L. Cleek , Daniel L. Crandall , James F. Davidson , Paul D. Drumheller , Cody L. Hartman , Theresa A. Holland , Thane L. Krazler , Mei Li , Gregory LoStracco , Bruce M. Steinhaus , Benjamin M. Trapp , Thomas G. Triebes
发明人： Carey V. Campbell , Robert L. Cleek , Daniel L. Crandall , James F. Davidson , Paul D. Drumheller , Cody L. Hartman , Theresa A. Holland , Thane L. Krazler , Mei Li , Gregory LoStracco , Bruce M. Steinhaus , Benjamin M. Trapp , Thomas G. Triebes
IPC分类号： A61M25/10
CPC分类号： A61M25/10 , A61L29/085 , A61L29/16 , A61L2300/602 , A61M2025/105 , A61M2025/1081 , F04C2270/0421
摘要： The invention is directed to eluting medical devices that enable consistent “on-demand” delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
摘要翻译： 本发明涉及洗脱能够使治疗剂向血管进行一致“按需”递送的医疗装置。 本发明的医疗装置包括可膨胀构件，亲水性涂层，其包括围绕可膨胀构件或结构层的至少一种治疗剂和具有可变可渗透微结构的外护套。 本文公开的设计和方法确保治疗剂递送基本上仅在可膨胀构件的膨胀期间发生，使涂覆和/或治疗剂对血流的损失最小化并提供受控递送至治疗部位。
-
公开(公告)号：US09320890B2
公开(公告)日：2016-04-26
申请号：US12941839
申请日：2010-11-08
CPC分类号： A61N1/056 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/222 , A61L2300/608 , A61N1/0568
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.
摘要翻译： 本发明涉及具有可释放地包含在材料内的治疗组合物的材料。 这些材料构造成以期望的速率释放治疗组合物。 本发明还涉及包含这些材料的装置。
-
公开(公告)号：US20110268781A1
公开(公告)日：2011-11-03
申请号：US13103885
申请日：2011-05-09
申请人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
发明人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
IPC分类号： A61F2/01 , G06F7/60 , A61P29/00 , A61K31/573 , A61P7/02
CPC分类号： A61L31/10 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/222 , A61L2300/608 , A61L2420/08 , A61N1/056 , A61N1/0568
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.
-
公开(公告)号：US09504771B2
公开(公告)日：2016-11-29
申请号：US13103885
申请日：2011-05-09
申请人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
发明人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
IPC分类号： A61N1/05 , A61K47/30 , A61K47/32 , A61K31/56 , A61F2/01 , A61P29/00 , A61K31/573 , A61P7/02 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/16
CPC分类号： A61L31/10 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/222 , A61L2300/608 , A61L2420/08 , A61N1/056 , A61N1/0568
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.
-
公开(公告)号：US20100233266A1
公开(公告)日：2010-09-16
申请号：US12404083
申请日：2009-03-13
CPC分类号： A61K9/06 , A61K9/0024 , A61K31/565 , A61K31/573 , A61K45/06 , A61K47/10 , A61K47/26 , A61K47/32 , A61K47/36 , A61K47/40 , A61L27/50 , A61L27/52 , A61L27/54 , A61L29/14 , A61L29/145 , A61L29/16 , A61L2300/416 , A61L2300/802
摘要： The present invention relates to articles and methods of treating vascular conditions with a thixotropic, turbid, bioactive agent-containing gel material capable of being essentially removed from an implantation site upon re-establishment of fluid flow at the implantation site.
摘要翻译： 本发明涉及使用具有触变性，混浊的含生物活性剂的凝胶材料治疗血管病症的制品和方法，其能够在植入部位重新建立流体流时基本上从植入部位移除。
-
公开(公告)号：US20110112618A1
公开(公告)日：2011-05-12
申请号：US12941839
申请日：2010-11-08
CPC分类号： A61N1/056 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/222 , A61L2300/608 , A61N1/0568
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.
摘要翻译： 本发明涉及具有可释放地包含在材料内的治疗组合物的材料。 这些材料构造成以期望的速率释放治疗组合物。 本发明还涉及包含这些材料的装置。
-
公开(公告)号：US20110098797A1
公开(公告)日：2011-04-28
申请号：US12909609
申请日：2010-10-21
IPC分类号： A61K31/573 , A61K9/00 , A61P29/00 , A61N1/05
CPC分类号： A61N1/0568 , A61L29/085 , A61L29/16 , A61L31/10 , A61L31/16 , A61L2300/608
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.031 秒)
