Spectroscopic feedback for high density data storage and micromachining
    1.
    发明授权
    Spectroscopic feedback for high density data storage and micromachining 失效
    高密度数据存储和微加工的光谱反馈

    公开(公告)号:US07426028B2

    公开(公告)日:2008-09-16

    申请号:US11375882

    申请日:2006-03-14

    IPC分类号: G01J3/28

    CPC分类号: G01J3/28 G01J3/443

    摘要: Optical breakdown by predetermined laser pulses in transparent dielectrics produces an ionized region of dense plasma confined within the bulk of the material. Such an ionized region is responsible for broadband radiation that accompanies a desired breakdown process. Spectroscopic monitoring of the accompanying light in real-time is utilized to ascertain the morphology of the radiated interaction volume. Such a method and apparatus as presented herein, provides commercial realization of rapid prototyping of optoelectronic devices, optical three-dimensional data storage devices, and waveguide writing.

    摘要翻译: 在透明电介质中通过预定的激光脉冲进行的光学击穿产生在该材料的主体内限制的致密等离子体的电离区域。 这样的电离区域负责伴随着所需的击穿过程的宽带辐射。 利用对实时伴随光的光谱监测来确定辐射相互作用体积的形态。 这样的方法和装置提供了光电器件,光学三维数据存储器件和波导写入的快速原型的商业实现。

    Fiber optic evaluation of tissue modification
    2.
    发明申请
    Fiber optic evaluation of tissue modification 审中-公开
    组织修复光纤评估

    公开(公告)号:US20060229515A1

    公开(公告)日:2006-10-12

    申请号:US11414009

    申请日:2006-04-27

    IPC分类号: A61B6/00

    摘要: An optical method and apparatus is utilized to evaluate the presence of tissue modification, in particular, to evaluate tissue ablation using light scattering spectroscopy realized via optical fiber(s). Such a technique allows for detection of the presence of tissue modification and provides depth information, such as, for example, depth of an ablated lesion. The method and apparatus as described herein can be used for in-vivo, real-time monitoring during predetermined procedures, such as, cardiac tissue ablation for therapeutic reasons.

    摘要翻译: 使用光学方法和装置来评估组织修饰的存在,特别是使用通过光纤实现的光散射光谱来评估组织消融。 这种技术允许检测组织修饰的存在并提供深度信息,例如消融损伤的深度。 本文所述的方法和装置可用于在预定程序期间的体内实时监测,例如用于治疗原因的心脏组织消融。

    ENHANCEMENT OF THE VISIBILITY OF OBJECTS LOCATED BELOW THE SURFACE OF A SCATTERING MEDIUM
    4.
    发明申请
    ENHANCEMENT OF THE VISIBILITY OF OBJECTS LOCATED BELOW THE SURFACE OF A SCATTERING MEDIUM 有权
    增强了位于散射介质表面下方的物体的可视性

    公开(公告)号:US20120062897A1

    公开(公告)日:2012-03-15

    申请号:US12880376

    申请日:2010-09-13

    申请人: Stavros Demos

    发明人: Stavros Demos

    IPC分类号: G01N21/55 G01N21/00

    摘要: Techniques are provided for enhancing the visibility of objects located below the surface of a scattering medium such as tissue, water and smoke. Examples of such an object include a vein located below the skin, a mine located below the surface of the sea and a human in a location covered by smoke. The enhancement of the image contrast of a subsurface structure is based on the utilization of structured illumination. In the specific application of this invention to image the veins in the arm or other part of the body, the issue of how to control the intensity of the image of a metal object (such as a needle) that must be inserted into the vein is also addressed.

    摘要翻译: 提供了用于增强位于散射介质如组织,水和烟雾的表面下方的物体的可视性的技术。 这种物体的实例包括位于皮肤下方的静脉,位于海面以下的矿井和在烟雾覆盖的位置处的人。 地下结构的图像对比度的增强是基于结构化照明的利用。 在本发明的具体应用中,为了使身体的手臂或其他部位的静脉成像,如何控制必须插入静脉中的金属物体(例如针头)的图像的强度的问题是 也解决了。

    Spectroscopic feedback for high density data storage and micromachining
    6.
    发明申请
    Spectroscopic feedback for high density data storage and micromachining 失效
    高密度数据存储和微加工的光谱反馈

    公开(公告)号:US20070188752A1

    公开(公告)日:2007-08-16

    申请号:US11375882

    申请日:2006-03-14

    IPC分类号: G01J3/28 G01N21/25

    CPC分类号: G01J3/28 G01J3/443

    摘要: Optical breakdown by predetermined laser pulses in transparent dielectrics produces an ionized region of dense plasma confined within the bulk of the material. Such an ionized region is responsible for broadband radiation that accompanies a desired breakdown process. Spectroscopic monitoring of the accompanying light in real-time is utilized to ascertain the morphology of the radiated interaction volume. Such a method and apparatus as presented herein, provides commercial realization of rapid prototyping of optoelectronic devices, optical three-dimensional data storage devices, and waveguide writing.

    摘要翻译: 在透明电介质中通过预定的激光脉冲进行的光学击穿产生在该材料的主体内限制的致密等离子体的电离区域。 这样的电离区域负责伴随着所需的击穿过程的宽带辐射。 利用对实时伴随光的光谱监测来确定辐射相互作用体积的形态。 这样的方法和装置提供了光电器件,光学三维数据存储器件和波导写入的快速原型的商业实现。

    Enhancement of the visibility of objects located below the surface of a scattering medium
    7.
    发明授权
    Enhancement of the visibility of objects located below the surface of a scattering medium 有权
    增强位于散射介质表面下方的物体的可视性

    公开(公告)号:US08586924B2

    公开(公告)日:2013-11-19

    申请号:US12880376

    申请日:2010-09-13

    申请人: Stavros Demos

    发明人: Stavros Demos

    IPC分类号: G01N21/55

    摘要: Techniques are provided for enhancing the visibility of objects located below the surface of a scattering medium such as tissue, water and smoke. Examples of such an object include a vein located below the skin, a mine located below the surface of the sea and a human in a location covered by smoke. The enhancement of the image contrast of a subsurface structure is based on the utilization of structured illumination. In the specific application of this invention to image the veins in the arm or other part of the body, the issue of how to control the intensity of the image of a metal object (such as a needle) that must be inserted into the vein is also addressed.

    摘要翻译: 提供了用于增强位于散射介质如组织,水和烟雾的表面下方的物体的可视性的技术。 这种物体的实例包括位于皮肤下方的静脉,位于海面以下的矿井和在烟雾覆盖的位置处的人。 地下结构的图像对比度的增强是基于结构化照明的利用。 在本发明的具体应用中,为了使身体的手臂或其他部位的静脉成像,如何控制必须插入静脉中的金属物体(例如针头)的图像的强度的问题是 也解决了。

    Hyperspectral microscope for in vivo imaging of microstructures and cells in tissues
    9.
    发明申请
    Hyperspectral microscope for in vivo imaging of microstructures and cells in tissues 有权
    高光谱显微镜用于组织中微观结构和细胞的体内成像

    公开(公告)号:US20070160279A1

    公开(公告)日:2007-07-12

    申请号:US11292406

    申请日:2005-11-30

    申请人: Stavros Demos

    发明人: Stavros Demos

    IPC分类号: G06K9/00 G02B21/00

    摘要: An optical hyperspectral/multimodal imaging method and apparatus is utilized to provide high signal sensitivity for implementation of various optical imaging approaches. Such a system utilizes long working distance microscope objectives so as to enable off-axis illumination of predetermined tissue thereby allowing for excitation at any optical wavelength, simplifies design, reduces required optical elements , significantly reduces spectral noise from the optical elements and allows for fast image acquisition enabling high quality imaging in-vivo. Such a technology provides a means of detecting disease at the single cell level such as cancer, precancer, ischemic, traumatic or other type of injury, infection, or other diseases or conditions causing alterations in cells and tissue micro structures.

    摘要翻译: 利用光学高光谱/多模式成像方法和装置为实现各种光学成像方法提供高信号灵敏度。 这样的系统利用长工作距离的显微镜物镜,以便使预定组织的轴外照明,从而允许在任何光学波长的激发,简化设计,减少所需的光学元件,显着降低来自光学元件的光谱噪声并允许快速图像 获取能够在体内实现高质量成像。 这种技术提供了检测单细胞水平的疾病的手段,例如癌症,癌前期,缺血性,创伤性或其它类型的损伤,感染或导致细胞和组织微结构改变的其它疾病或病症。