Abstract:
A method for immobilizing glycoprotein is disclosed. A surface is provided. Next, a boronic acid is contacted to the surface. The boronic acid is represented as Y—R—B—(OH)2 and includes a boronic acid group (B—(OH)2), a linker R, and a functional group Y, in which the boronic acid is bonded to the surface via the functional group Y. A glycoprotein is contacted to the boronic acid, wherein two spatially adjacent hydroxyl groups of a carbohydrate chain form a boronate ester with the boronic acid group of the boronic acid to immobilize the glycoprotein. The goal of site-specific and covalent protein immobilization without interfering the binding affinity of an antibody to antigen may be thus achieved with the reaction of boronic acid and the carbohydrate chain of Fc region.
Abstract:
The present invention provides methods, compositions, and systems for mass spectrometric analysis of magnetic nanoparticles displaying ligands on their surface. For example, the present invention provides methods of screening a sample for the presence of at least one analyte using ligand conjugated magnetic nanoparticles, magnetic separation, and mass spectrometric analysis. The present invention also relates to MALDI matrix compositions comprising ligand conjugated magnetic nanoparticles.
Abstract:
The present invention provides methods and compositions for carbohydrate encapsulated nanoparticle based mass spectrometry. For example, the present invention provides methods of screening samples for carbohydrate binding molecules, methods of characterizing carbohydrate binding epitopes in target molecules, and MALDI matrix compositions comprising carbohydrate encapsulated nanoparticles.
Abstract:
The present invention provides methods, compositions, and systems for mass spectrometric analysis of magnetic nanoparticles displaying ligands on their surface. For example, the present invention provides methods of screening a sample for the presence of at least one analyte using ligand conjugated magnetic nanoparticles, magnetic separation, and mass spectrometric analysis. The present invention also relates to MALDI matrix compositions comprising ligand conjugated magnetic nanoparticles.
Abstract:
A cane includes a tube, an extension rod telescopically mounted within one end of the tube, and a control mechanism sandwiched between the tube and the extension rod. The tube defines a first aperture and a second aperture. The extension rod defines a plurality of holes. The control mechanism is movable among a first position where the control mechanism is positioned in a selected one of the holes in the extension rod, and the tube, the extension rod and the control mechanism are prohibited from moving axially with respect to one another; a second position where the extension rod and the control mechanism together are allowed to move axially with respect to the tube; and a third position where the extension rod is allowed to move axially with respect to the control mechanism and the tube.
Abstract:
A cane includes a tube, an extension rod telescopically mounted within one end of the tube, and a control mechanism sandwiched between the tube and the extension rod. The tube defines a first aperture and a second aperture. The extension rod defines a plurality of holes. The control mechanism is movable among a first position where the control mechanism is positioned in a selected one of the holes in the extension rod, and the tube, the extension rod and the control mechanism are prohibited from moving axially with respect to one another; a second position where the extension rod and the control mechanism together are allowed to move axially with respect to the tube; and a third position where the extension rod is allowed to move axially with respect to the control mechanism and the tube.
Abstract:
A color pattern film for metal shell is provided. The color pattern film for metal shell includes a transparent polymer substrate, a releasing coating layer, a protective layer, an ink layer, and an adhesive layer. The releasing coating layer is on the transparent polymer substrate, the protective layer is on the releasing coating layer, the ink layer is on the protective layer, and the adhesive layer is on the ink layer. The adhesive layer at least includes a base resin which is one of resin systems selected from ethylene-vinyl acetate (EVA), polyester (PET) resin, and polyolefin resin. The color pattern film for metal shell can be directly pressed and attached onto a metal sheet or coil, and subsequently punched, thus the problems of the prior art that the yield of adhesive wet film coating process is not easily controlled and complex post-processes are still required after molding are addressed.
Abstract:
A driving electrode structure of a plasma display panel for improving operation margin is described. A plurality openings is formed in a transparent electrode according to the driving characteristics of fluorescent layer of each luminous cell to adjust the effective area of the transparent electrode in each luminous cell, thereby increasing the operation margin of the sustaining voltage.
Abstract:
An antenna-embedded electronic device case includes an electrically-insulated case wall, a lower and an upper ground conductive layers, a lower and an upper electrically-insulated layer, and a continuous conductive layer. The lower ground conductive layer is in contact with the electrically-insulated case wall. The lower and upper electrically-insulated layers are sandwiched between the lower and upper ground conductive layers. The continuous conductive layer has a first portion sandwiched between the lower and upper electrically-insulated layers and a second portion protruding out to serve as an antenna radiator for transmitting or receiving electromagnetic signals.
Abstract:
A temperature and humidity sensing device including a body and a temperature and humidity sensor is provided. The body has an inlet hole, an outlet hole, and a flow channel. The inlet hole and the outlet hole are opposite to each other, and the flow channel is configured to communicate the inlet hole and the outlet hole. The temperature and humidity sensor is disposed in the flow channel. The temperature and humidity sensor is configured to sense the relative humidity of air in the surrounding environment of the body during the air in the surrounding environment of the body flows into the flow channel from the inlet hole and flows through the flow channel to flow out from the outlet hole.