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公开(公告)号：US11490623B2
公开(公告)日：2022-11-08
申请号：US16846770
申请日：2020-04-13
发明人： Carl Myers , Carlo Daep , Lynette Zaidel , James Masters , Russell Composto , Hyun-Su Lee
IPC分类号： A01N47/44 , C11D3/37 , A61K31/785 , A61Q17/00 , C11D3/48 , A61Q11/00 , C08F126/02 , A61K8/91 , A01N25/08 , A61K8/81 , C08F8/30 , C09D5/14 , C09D139/00
摘要： Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
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公开(公告)号：US10653149B2
公开(公告)日：2020-05-19
申请号：US15788852
申请日：2017-10-20
发明人： Carl Myers , Carlo Daep , Lynette Zaidel , James Masters , Russell Composto , Hyun-Su Lee
IPC分类号： A61K31/785 , A61Q11/00 , C08F126/02 , A01N47/44 , C11D3/37 , A61Q17/00 , C11D3/48 , A61K8/81 , C08F8/30 , C09D5/14 , C09D139/00 , A61K8/91 , A01N25/08
摘要： Antimicrobial compositions and methods for depositing or coating the antimicrobial or antibacterial compositions on a substrate to prevent microbial adhesion are provided. The antimicrobial composition may include a cationic polymer having a poly-allylamine backbone. A portion of the poly-allylamine backbone may be functionalized with at least one of a guanidine functional group and a biguanide functional group.
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公开(公告)号：US11197811B2
公开(公告)日：2021-12-14
申请号：US16798492
申请日：2020-02-24
发明人： Zhiqiang Liu , Long Pan , Shaotang Yuan , Jairajh Mattai , James Masters
摘要： Described herein are methods of cleaning a tooth comprising administering a composition comprising a zinc amino acid halide complex to the oral cavity; and retaining the composition in the oral cavity for a time sufficient to form a precipitate.
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公开(公告)号：US10548829B2
公开(公告)日：2020-02-04
申请号：US16266661
申请日：2019-02-04
发明人： Jane Ong , James Masters , Tatiana Brinzari , Chi-Yuan Cheng , Donghui Wu , Long Pan
摘要： Disclosed herein are oral care compositions comprising naringin:Zinc complexes having a 2:1 naringin to zinc molar ratio. Methods of making and using the compositions are also provided.
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公开(公告)号：US11116708B2
公开(公告)日：2021-09-14
申请号：US16758434
申请日：2017-12-19
发明人： Shujiang Cheng , Zeenat Nabi , Laurence Du-Thumm , Qiang Wu , Jane Ong , Halyna Siomyk , Harsh Mahendra Trivedi , James Masters , Chi-Yuan Cheng , Donghui Wu
摘要： Personal care compositions including a naringin:zinc complex and methods for preparing and using the same are provided. The personal care compositions may include a carrier and a naringin:zinc complex having a 2:1 naringin to zinc molar ratio.
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公开(公告)号：US10524995B2
公开(公告)日：2020-01-07
申请号：US15964193
申请日：2018-04-27
发明人： Long Pan , Shaotang Yuan , Shira Pilch , James Masters , Zhiqiang Liu
摘要： Disclosed herein are mouthwashes comprising a complex of a zinc ion source and an amino acid. Methods of making and using the compositions are also provided.
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公开(公告)号：US10195125B2
公开(公告)日：2019-02-05
申请号：US15668857
申请日：2017-08-04
发明人： Long Pan , Jairajh Mattai , Shaotang Yuan , James Masters
IPC分类号： A61K8/27 , A61K8/44 , A61Q11/00 , A61Q5/02 , A61Q19/10 , A61Q17/00 , A61Q15/00 , A61Q5/12 , C07F3/06
摘要： The invention provides a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl− having antibacterial and antiperspirant properties, together with personal care compositions comprising the complex, and methods of making and using these complexes and compositions.
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公开(公告)号：US11957778B2
公开(公告)日：2024-04-16
申请号：US16406069
申请日：2019-05-08
IPC分类号： A61K8/73 , A61K8/34 , A61K8/92 , A61K8/9794 , A61Q11/00
CPC分类号： A61K8/735 , A61K8/345 , A61K8/922 , A61K8/9794 , A61Q11/00
摘要： Disclosed herein are oral care compositions comprising hemp seed oil and caprylyl glycol. In certain embodiments, the oral care composition optionally further comprises one or more ingredients selected from hyaluronic acid and aloe vera. Methods of making and using the compositions are also provided.
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公开(公告)号：US20210318306A1
公开(公告)日：2021-10-14
申请号：US17301428
申请日：2021-04-02
IPC分类号： G01N33/566 , G01N33/543 , A61K33/30 , A61K33/16 , G01N33/50 , A61P31/04
摘要： Methods for identifying a composition that neutralizes toxicity of a lipopolysaccharide are disclosed. The methods comprise comparing the amount of cytokine and/or prostaglandin E2 secreted by cells that have Toll-like receptors activated by a lipopolysaccharide in the presence or absence of a test composition. Methods of neutralizing toxicity of a lipopolysaccharide in an individual's oral cavity using compositions identified neutralizing toxicity of a lipopolysaccharide are also disclosed. Method of neutralizing toxicity of a lipopolysaccharide in an individual's oral cavity using oral care compositions that comprise combinations of zinc oxide and zinc citrate are also disclosed.
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10.发明申请公开(公告)号：US20210308028A1
公开(公告)日：2021-10-07
申请号：US17301257
申请日：2021-03-30
发明人： Ying Yang , James Masters , Harsh Mahendra Trivedi , Tulika Sarma
摘要： Method of improving tissue integrity of tissue that functions as a barrier are provided. Method of protecting and maintaining tissue integrity of tissue that functions as a barrier are provided. Method of repairing damage to tissue that functions as a barrier, and to restoring and improving function of such damaged tissue are provided. Methods of improving, maintaining, protecting, repairing and/or restoring the integrity of tissue which functions as a barrier and repair of damage to and healing of wounds to such tissue improves, maintains, protects, repairs and restores immunity. The methods comprising contacting the tissue with an effective amount of a composition comprising one or more sources of zinc ions such as zinc oxide, zinc citrate, or combination thereof zinc oxide and zinc citrate, and optionally further comprising arginine and/or one or more neutral amino acids.
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