摘要:
A microfluidic device comprising independently addressable arrays of interdigitated electrodes can be used to assembly and transport large-scale microparticle structures. The device and method uses collective phenomena in a negatively polarized suspension exposed to a high-gradient strong ac electric field to assemble the particles into predetermined locations and then transport them collectively to a work area for final assembly by sequentially energizing the electrode arrays.
摘要:
Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)—{N-[(3-t-butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)—{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity.
摘要:
Chiral 1-(4-methylphenylmethyl)-5-oxo-{N-[(3-t-butoxycarbonyl-aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamides as inhibitors of collagen induced platelet activation and adhesion The present invention provides chiral (2S)-1-(4-methyl-phenylmethyl)-5-oxo-(3S)-{N-[(3-t butoxycarbonyl aminomethyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide, and (2S)-1-(4-methylphenylmethyl)-5-oxo-(3R)-{N-[(3-t-butoxycarbonyl amino methyl)]-piperidin-1-yl}-pyrrolidine-2-carboxamide of formula 6 and 7 respectively. The present invention also relates to use of these moieties as inhibitors of collagen induced platelet adhesion and aggregation mediated through collagen receptors. The present invention provides a process for preparation of chiral carboxamides of formula 6 and 7 using the process which has advantage to avoid any racemization at the a-carboxylic center, during N-alkylation. The reagent LiHMDS is used at low temperatures to furnish methyl N-(p methylphenylmethyl)lpyroglutamate in good chiral purity.
摘要:
The present disclosure provides for new photoalignment (co)polymer materials which demonstrate improved adhesion to a substrate. The (co)polymeric structure includes at least one photochemically active chromophore and at least one adhesion promoter group. Articles of manufacture, optical elements, ophthalmic elements and liquid crystal cells which include at least one photoalignment layer made from the photoalignment (co)polymer materials and methods for formation are also disclosed.
摘要:
Systems and methods to exchange data between a vehicle and a remote computer system, are disclosed. In one embodiment, a system to exchange data between a vehicle and a remote computer system comprises at least one power line adapted to couple to the vehicle, a local area network, a modem coupled to the local area network and the at least one power line, and a power line interference server comprising logic to allocate communication channels within a specified frequency range on the power line. Other embodiments may be described.
摘要:
In embodiments, apparatuses, methods and storage media are described that are associated with controlling production of images on a camera. In embodiments, a device with a camera, such as a content consumption device, may determine a current orientation of the camera and may adjust production of images from the camera to account for the orientation. The device may determine the orientation based on physical data, such as data from an accelerometer, compass, and/or gyroscope. the device may also determine the orientation from image data. The device may adjust production of images by either before capture, such as by physically adjusting the orientation of the camera, or after capture, such as by panning, tilting, and/or zooming captured images. Other embodiments may be described and claimed.
摘要:
Described herein are compounds generally comprising an indeno[2′,3′:3,4]naptho[1,2-b]pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions may further comprise other photochromic compositions and/or materials. Additionally, such compounds and/or compositions may be suitable for preparing certain photochromic articles.
摘要:
In embodiments, apparatuses, methods and storage media are described that are associated with remote control of media devices. In embodiments, a remote control and a content player may be configured to facilitate a secured pairing process. The remote control may be configured to send non-secured signals (such as through an IR transmitter) as well as send and receive secured signals (such as via Bluetooth™ using an RF transceiver). The remote control, in response to being turned on or asked to pair, may send a pairing request to the player that includes an identifier for the remote control and which identifies the remote control as an eligible pairing device without requiring separate entry of a security code by a user. The remote control and player may then perform a pairing process without requiring additional action on the part of a user. Other embodiments may be described and/or claimed.
摘要:
Provided are phase-separating polymer systems including a cured polymeric liquid crystal matrix phase and a guest phase including at least one photoactive material where the guest phase separates from the matrix phase during the curing process. Optical elements, including ophthalmic elements and other articles of manufacture including the phase-separating polymer systems are also disclosed. Methods of forming a liquid crystal phase-separating photoactive polymer system are also described.
摘要:
A system synchronizes digital messages from one user's multiple digital message accounts into one mailbox. The user identifies the message accounts from which digital messages are to be aggregated. When a new digital message arrives for one of the message accounts, a server providing the message-dependent storage sends an arrival notification to a synchronization system, or is accessed by the synchronization system at various points to check for message arrival, when notification is not forthcoming. Upon determining the arrival of a new digital message, the synchronization system retrieves the new digital message(s) and stores the retrieved message(s) in an integrated mailbox provided by the synchronization system, so that messages from various digital message accounts are collected into the integrated mailbox. This allows the user to manipulate messages in each of the individual accounts using the integrated mailbox without having to access the various accounts individually.