公开(公告)号：US07191008B2

公开(公告)日：2007-03-13

申请号：US10057419

申请日：2002-01-25

申请人： Craig L. Schmidt ,  Paul M. Skarstad ,  Nathan A. Torgerson ,  John J. Grevious ,  Steven L. Jensen ,  John W. Forsberg ,  Robert Leinders ,  Raymond F. McMullen

发明人： Craig L. Schmidt ,  Paul M. Skarstad ,  Nathan A. Torgerson ,  John J. Grevious ,  Steven L. Jensen ,  John W. Forsberg ,  Robert Leinders ,  Raymond F. McMullen

IPC分类号： A61N1/08

CPC分类号： A61N1/08 ,  A61N1/378 ,  A61N1/3787 ,  A61N1/3975

摘要： An implantable medical device includes a control circuit for controlling the operation of the device and for obtaining physiological data from a patient in which the medical device is implanted. The implanted device also includes a communication circuit for transmitting the physiological data to an external device. A first power source is coupled to the control circuit and provides power to the control circuit. A second power source is coupled to the communication circuit and provides power to the communication circuit.

摘要翻译： 可植入医疗装置包括控制电路，用于控制装置的操作并从用于从其中植入医疗装置的患者获得生理数据。 植入装置还包括用于将生理数据发送到外部装置的通信电路。 第一电源耦合到控制电路并向控制电路提供电力。 第二电源耦合到通信电路并向通信电路提供电力。

公开(公告)号：US06456883B1

公开(公告)日：2002-09-24

申请号：US09558664

申请日：2000-04-26

申请人： Nathan A. Torgerson ,  John J. Grevious ,  Steven L. Jensen ,  John W. Forsberg ,  Robert Leinders ,  Raymond F. McMullen

发明人： Nathan A. Torgerson ,  John J. Grevious ,  Steven L. Jensen ,  John W. Forsberg ,  Robert Leinders ,  Raymond F. McMullen

IPC分类号： A61N1378

CPC分类号： A61N1/372 ,  A61F2250/0002 ,  A61M5/14276 ,  A61M2205/3523 ,  A61M2205/8206 ,  A61N1/08 ,  A61N1/3787

摘要： An apparatus and method that will allow for external communication, via an external programmer, for positive device identification and for retrieval of device or patient information stored by an implantable medical device with a depleted power source. The external programmer will deliver energy to a secondary power source located inside the implanted device using RF telemetry sufficient to charge up the secondary power source, e.g., a small capacitor. The capacitor will charge up immediately within milliseconds. Once the secondary power source is sufficiently charged, it can be used to power up a controller having the stored information in the implantable medical device. Once the controller is operational, the implanted device will transmit device and patient information to the external programmer via RF telemetry.

摘要翻译： 将允许通过外部编程器进行外部通信的设备和方法用于正器件识别以及用于耗尽功率源的由可植入医疗器件存储的装置或患者信息的检索。 外部编程器将使用足以使二次电源例如小电容器充电的RF遥测来将能量传递到位于植入装置内部的次级电源。 电容器将在几毫秒内立即充电。 一旦辅助电源充足电，就可以将具有存储信息的控制器加电到可植入医疗设备中。 一旦控制器运行，植入的设备将通过RF遥测将设备和患者信息传送到外部编程器。

公开(公告)号：US06950706B2

公开(公告)日：2005-09-27

申请号：US10133513

申请日：2002-04-26

申请人： John Delfin Rodriguez ,  Nathan A. Torgerson ,  Marc Stein ,  Steven L. Jensen

发明人： John Delfin Rodriguez ,  Nathan A. Torgerson ,  Marc Stein ,  Steven L. Jensen

IPC分类号： A61N1/34 ,  A61N1/36 ,  A61N1/372 ,  A61N1/00

CPC分类号： A61N1/36071

摘要： In the embodiment of the invention, apparatus and method provide flexibility in generating a stimulation waveform (that comprises at least a stimulation pulse) to an electrode of an Implantable Neuro Stimulator (INS). The waveform is synthesized for each rate period interval. A portion of the rate period interval is identified, in which the portion comprises at least one phase. During each phase, the stimulation waveform is synthesized by a waveform controller and a waveform generator. The waveform controller utilizes waveform parameters, e.g. the initial value, final value, and step time duration, to form a digital signal to the waveform generator. The waveform generator utilizes the digital signal to form the synthesized waveform.

摘要翻译： 在本发明的实施例中，装置和方法提供了向植入式神经刺激器（INS）的电极生成刺激波形（至少包括刺激脉冲）的灵活性。 每个速率周期间隔合成波形。 识别速率周期间隔的一部分，其中该部分包括至少一个相位。 在每个阶段，刺激波形由波形控制器和波形发生器合成。 波形控制器利用波形参数，例如 初始值，最终值和步长持续时间，以形成到波形发生器的数字信号。 波形发生器利用数字信号形成合成波形。

公开(公告)号：US08583254B2

公开(公告)日：2013-11-12

申请号：US13338751

申请日：2011-12-28

申请人： Steven L. Jensen ,  Dwight E. Nelson

发明人： Steven L. Jensen ,  Dwight E. Nelson

IPC分类号： A61N1/05

CPC分类号： A61N1/36146 ,  A61N1/0534 ,  A61N1/36067 ,  A61N1/36082 ,  A61N1/36139

摘要： This disclosure describes techniques for delivering electrical stimulation at one or more phases relative to an ongoing oscillating signal in a patient, and then mapping the response to the oscillating signal. The techniques may reduce or eliminate the oscillating signal. In one example, the disclosure is directed to a method that includes delivering a set of first electrical stimulation at a plurality of phases relative to an oscillating signal, measuring a response in the oscillating signal to the set of first electrical stimulation after delivering electrical stimulation at each respective phase of the plurality of phases, determining a phase at which to deliver second electrical stimulation based on the measured responses, and delivering the second electrical stimulation to the patient at the determined phase to produce a therapeutic effect.

摘要翻译： 本公开描述了相对于患者中正在进行的振荡信号在一个或多个相位递送电刺激的技术，然后将响应映射到振荡信号。 这些技术可以减少或消除振荡信号。 在一个示例中，本公开涉及一种方法，其包括相对于振荡信号在多个相位递送一组第一电刺激，在将电刺激传递到第一电刺激之后测量振荡信号中的响应到第一电刺激 确定基于所测量的响应来传递第二电刺激的相位，以及在确定的阶段将第二电刺激递送给患者以产生治疗效果。

公开(公告)号：US4788975A

公开(公告)日：1988-12-06

申请号：US117666

申请日：1987-11-05

申请人： Leonid Shturman ,  Steven L. Jensen

发明人： Leonid Shturman ,  Steven L. Jensen

IPC分类号： A61B5/0456 ,  A61B18/20 ,  A61B17/36

CPC分类号： A61B18/20 ,  A61B5/0456 ,  A61B2018/00636

摘要： A control system and method for laser angioplasty or laser ablation or welding of tissue in general, in which firing of a laser catheter is correlated with movement of a vessel or other body chamber carrying the laser catheter, whereby the laser is fired only during those times its fiberoptic-delivered beam is aimed at plaque or other target in the vessel or chamber.

摘要翻译： 用于激光血管成形术或激光烧蚀或组织焊接的控制系统和方法，其中激光导管的点火与携带激光导管的容器或其他体腔的运动相关，由此激光仅在那些时间点燃 其光纤输送束瞄准血管或腔室中的斑块或其他靶。

公开(公告)号：US08447406B2

公开(公告)日：2013-05-21

申请号：US12826172

申请日：2010-06-29

申请人： Jianping Wu ,  Steven L. Jensen ,  Dwight E. Nelson

发明人： Jianping Wu ,  Steven L. Jensen ,  Dwight E. Nelson

IPC分类号： A61B5/0482 ,  A61N1/08

CPC分类号： A61N1/00

摘要： Bioelectrical signals may be sensed within the brain by two or more electrodes to determine characteristics of a function of the brain. The signals obtained by the electrodes may be plotted over time to determine whether the brain function exhibits a normal or an abnormal pattern. If the brain function exhibits an abnormal pattern, an implantable medical device may dynamically determine based on the abnormal pattern and a previously-obtained plot associated with normal brain function, an appropriate electrical stimulation therapy. Application of the appropriate electrical stimulation therapy causes the brain function to shift from the abnormal pattern to the normal pattern.

摘要翻译： 可以通过两个或更多个电极在脑内感测生物电信号，以确定大脑功能的特征。 可以随时间绘制由电极获得的信号，以确定脑功能是否呈现正常或异常图案。 如果大脑功能呈现异常模式，则植入式医疗设备可以基于异常模式和与正常脑功能相关联的先前获得的情景（适当的电刺激治疗）来动态地确定。 适当的电刺激治疗的应用使脑功能从异常模式转移到正常模式。

公开(公告)号：US06941332B2

公开(公告)日：2005-09-06

申请号：US10128021

申请日：2002-04-23

申请人： Steven L. Jensen

发明人： Steven L. Jensen

IPC分类号： A61N1/36 ,  G06F19/00 ,  G06F17/10

CPC分类号： G06F19/3481 ,  A61N1/025 ,  A61N1/3605 ,  A61N1/37252 ,  G06F19/00 ,  G16H40/63

摘要： A method for fast median filtering in an implantable medical device is disclosed that provides rapid filtering using computational mechanisms with following elements. A new sample value is received into a buffer. An oldest sample value location is identified in a MIN-heap and a MAX-heap. A new sample value location is identified in either the MIN-heap or the MAX-heap by comparing the new sample value to a median value. The new sample value is placed into the oldest sample value location, if the MIN-heap or MAX-heap identified for the new sample value location is the same as the MIN-heap or MAX-heap identified for the oldest sample value location. A MIN-heap top or MAX-heap top is moved from the heap not containing the oldest value into the location of the oldest sample and the new sample is placed into the location of the MIN-heap top or MAX-heap top moved from the heap not containing the oldest value, if the heap identified for the new sample is not the same as the heap identified for the oldest sample. The MAX-heap is rebalanced so the MAX-heap top contains the highest value in the MAX-heap and the MIN-heap is rebalanced so the MIN-heap top contains the lowest value in the MIN-heap. The median value is calculated by averaging the MIN-heap top plus the MAX-heap top. The method for fast median filtering in an implantable medical device can also be expressed as a computer software product that includes a medium readable by a processor.

摘要翻译： 公开了一种用于可植入医疗装置中的快速中值滤波的方法，其使用具有以下元件的计算机制来提供快速滤波。 一个新的采样值被接收到一个缓冲区。 最早的样本值位置在MIN堆和MAX堆中被标识。 通过将新样本值与中值进行比较，可以在MIN堆或MAX堆中识别新的样本值位置。 如果为新样本值位置标识的MIN-heap或MAX-stack与为最旧样本值位置标识的MIN-heap或MAX-heap相同，则将新样本值放入最旧的样本值位置。 最小堆顶或最大堆顶从不包含最旧值的堆中移动到最旧样本的位置，并将新样本放入MIN堆顶或MAX堆堆顶的位置 堆不包含最旧的值，如果为新样本标识的堆不同于为最旧样本确定的堆。 MAX堆重新平衡，所以MAX堆顶部包含MAX堆中的最高值，MIN堆重新平衡，所以MIN堆最小值包含MIN堆中的最低值。 中值是通过对MIN堆堆加上MAX堆顶的平均值来计算的。 用于可植入医疗装置中的快速中值滤波的方法也可以表示为包括可由处理器读取的介质的计算机软件产品。

公开(公告)号：US06045573A

公开(公告)日：2000-04-04

申请号：US235367

申请日：1999-01-21

申请人： Richard F. Wenstrom, Jr. ,  Ronald L. Taylor, Jr. ,  Steven L. Jensen

发明人： Richard F. Wenstrom, Jr. ,  Ronald L. Taylor, Jr. ,  Steven L. Jensen

IPC分类号： A61B17/58 ,  A61B17/04

CPC分类号： A61B17/0401 ,  A61F2/0811 ,  A61B2017/0403 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/044 ,  A61F2002/0888 ,  Y10S606/916

摘要： A suture anchor for attaching soft tissue to bone. The anchor has a body member and a longitudinal axis. The anchor contains at least two suture mounting passages for mounting suture to the anchor. A first passage is located proximally to the second passage.

摘要翻译： 用于将软组织粘附到骨头的缝合锚。 锚具有主体构件和纵向轴线。 锚固体包含至少两个用于将缝合线固定到锚固件上的缝合线安装通道。 第一通道位于第二通道的近侧。

公开(公告)号：US08396565B2

公开(公告)日：2013-03-12

申请号：US10691917

申请日：2003-10-23

申请人： Ruchika Singhal ,  Robert M. Skime ,  Steven L. Jensen

发明人： Ruchika Singhal ,  Robert M. Skime ,  Steven L. Jensen

IPC分类号： A61N1/18

CPC分类号： A61N1/36071 ,  A61B5/1116 ,  A61B5/1118 ,  A61N1/36132 ,  A61N1/36135 ,  A61N1/36139 ,  A61N1/36535 ,  A61N1/36542 ,  A61N1/37264 ,  G06F19/00

摘要： A medical device detects a previously defined event, and controls delivery of therapy to a patient according to therapy information associated with the previously defined event. In exemplary embodiments, the medical device enters a learning mode in response to a command received from a user, e.g., the patient or a clinician. In such embodiments, the medical device defines the event, collects the therapy information, and associates the therapy information with the defined event while operating in the learning mode. In some embodiments, the medical device defines the event based on the output of a sensor that indicates a physiological parameter of the patient during the learning mode. The sensor may be an accelerometer, which generates an output that reflects motion and/or posture of the patient. The medical device may collect therapy information by recording therapy changes made by the user during the learning mode.

摘要翻译： 医疗设备检测先前定义的事件，并且根据与先前定义的事件相关联的治疗信息来控制对患者的治疗递送。 在示例性实施例中，医疗设备响应于从用户（例如患者或临床医生）接收的命令进入学习模式。 在这样的实施例中，医疗设备定义事件，收集治疗信息，并且在学习模式下操作时将治疗信息与定义的事件相关联。 在一些实施例中，医疗设备基于在学习模式期间指示患者的生理参数的传感器的输出来定义事件。 传感器可以是加速度计，其产生反映患者的运动和/或姿势的输出。 医疗装置可以通过在学习模式下记录用户进行的治疗改变来收集治疗信息。

公开(公告)号：US20110319962A1

公开(公告)日：2011-12-29

申请号：US12826172

申请日：2010-06-29

申请人： Wu Jianping ,  Steven L. Jensen ,  Dwight E. Nelson

发明人： Wu Jianping ,  Steven L. Jensen ,  Dwight E. Nelson

IPC分类号： A61N1/05

CPC分类号： A61N1/00

摘要： Bioelectrical signals may be sensed within the brain by two or more electrodes to determine characteristics of a function of the brain. The signals obtained by the electrodes may be plotted over time to determine whether the brain function exhibits a normal or an abnormal pattern. If the brain function exhibits an abnormal pattern, an implantable medical device may dynamically determine based on the abnormal pattern and a previously-obtained plot associated with normal brain function, an appropriate electrical stimulation therapy. Application of the appropriate electrical stimulation therapy causes the brain function to shift from the abnormal pattern to the normal pattern.

摘要翻译： 可以通过两个或更多个电极在脑内感测生物电信号，以确定大脑功能的特征。 可以随时间绘制由电极获得的信号，以确定脑功能是否呈现正常或异常图案。 如果大脑功能呈现异常模式，则植入式医疗设备可以基于异常模式和与正常脑功能相关联的先前获得的情景（适当的电刺激治疗）来动态地确定。 适当的电刺激治疗的应用使脑功能从异常模式转移到正常模式。