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公开(公告)号：US20050064458A1
公开(公告)日：2005-03-24
申请号：US10863332
申请日：2004-06-09
申请人： Craig Rosen , Steven Ruben , Paul Moore , Paul Young , George Komatsoulis , Charles Birse , Roxanne Duan , Kimberly Florence , Daniel Soppet
发明人： Craig Rosen , Steven Ruben , Paul Moore , Paul Young , George Komatsoulis , Charles Birse , Roxanne Duan , Kimberly Florence , Daniel Soppet
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K39/395 , A61K48/00 , A61P1/04 , A61P7/00 , A61P7/04 , A61P7/06 , A61P9/10 , A61P11/06 , A61P17/02 , A61P17/06 , A61P17/12 , A61P19/02 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/22 , A61P25/24 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/18 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/04 , A61P43/00 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/566 , C07H21/04 , C12N9/00
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20080051338A1
公开(公告)日：2008-02-28
申请号：US11777133
申请日：2007-07-12
申请人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
发明人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
IPC分类号： A61K31/70 , A61K38/00 , C07K14/00 , C07K16/18 , C12N15/00 , C12N15/11 , C12N15/87 , C12N5/06 , C12P21/04 , C12Q1/68 , G01N33/53
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20060079670A1
公开(公告)日：2006-04-13
申请号：US11229769
申请日：2005-09-20
申请人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
发明人： George Komatsoulis , Craig Rosen , Steven Ruben , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Ying-Fei Wei , Jian Ni , Kimberly Florence , Paul Young , Laurie Brewer , Daniel Soppet , Gregory Endress , Reinhard Ebner , Henrik Olsen , Michael Mucenski
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050095612A1
公开(公告)日：2005-05-05
申请号：US10866831
申请日：2004-06-15
申请人： Steven Ruben , Paul Young , Laurie Brewer , Reinhard Ebner , Henrik Olsen , Kimberly Florence , Craig Rosen , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Charles Florence , Daniel Soppet , Gregory Endress , Ping Feng , George Komatsoulis
发明人： Steven Ruben , Paul Young , Laurie Brewer , Reinhard Ebner , Henrik Olsen , Kimberly Florence , Craig Rosen , Roxanne Duan , Paul Moore , Yanggu Shi , David LaFleur , Charles Florence , Daniel Soppet , Gregory Endress , Ping Feng , George Komatsoulis
IPC分类号： G01N33/53 , A61K38/00 , A61P43/00 , C07K14/47 , C07K16/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/68 , C07H21/04 , C12N9/00
CPC分类号： C07K14/47 , A61K38/00 , G01N33/6893 , G01N2500/20
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的病症的诊断和治疗方法。
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公开(公告)号：US20050208619A1
公开(公告)日：2005-09-22
申请号：US10878523
申请日：2004-06-29
申请人： Craig Rosen , Steven Ruben , Reinhard Ebner , Roxanne Duan , Jian Ni , Daniel Soppet , Paul Moore , Yanggu Shi , David LaFleur , Henrik Olsen , Charles Birse , George Komatsoulis
发明人： Craig Rosen , Steven Ruben , Reinhard Ebner , Roxanne Duan , Jian Ni , Daniel Soppet , Paul Moore , Yanggu Shi , David LaFleur , Henrik Olsen , Charles Birse , George Komatsoulis
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P9/10 , A61P17/02 , A61P17/06 , A61P25/00 , A61P25/02 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/28 , A61P29/00 , A61P31/00 , A61P31/04 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06 , C07H21/04 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/00 , C12N15/09 , C12P21/02 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C07H21/04 , C07K14/47 , C07K16/18 , C07K2317/622 , C07K2319/30
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20050010042A1
公开(公告)日：2005-01-13
申请号：US10919272
申请日：2004-08-17
申请人： Steven Ruben , Charles Birse , Roxanne Duan , Daniel Soppet , Craig Rosen , Yanggu Shi , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Jian Ni , Paul Young
发明人： Steven Ruben , Charles Birse , Roxanne Duan , Daniel Soppet , Craig Rosen , Yanggu Shi , David LaFleur , Henrik Olsen , Reinhard Ebner , Kimberly Florence , Jian Ni , Paul Young
IPC分类号： G01N33/50 , A61K31/711 , A61K38/00 , A61P1/04 , A61P7/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/06 , A61P19/02 , A61P27/02 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/06 , C07K14/47 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , G01N33/15 , G01N33/53 , C12Q1/68 , C07H21/04
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
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公开(公告)号：US20050019866A1
公开(公告)日：2005-01-27
申请号：US10883936
申请日：2004-07-06
申请人： Jian Ni , Kevin Baker , Charles Birse , Michele Fiscella , George Komatsoulis , Craig Rosen , Daniel Soppet , Paul Young , Reinhard Ebner , D. Duan , Henrik Olsen , David La Fleur , Paul Moore , Yanggu Shi , Ping Wei , Kimberly Florence
发明人： Jian Ni , Kevin Baker , Charles Birse , Michele Fiscella , George Komatsoulis , Craig Rosen , Daniel Soppet , Paul Young , Reinhard Ebner , D. Duan , Henrik Olsen , David La Fleur , Paul Moore , Yanggu Shi , Ping Wei , Kimberly Florence
IPC分类号： G01N33/50 , A61K38/00 , A61K48/00 , A61P43/00 , C07K14/47 , C07K14/705 , C07K16/18 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566 , C07H21/04 , C12N9/42
CPC分类号： C07K14/70532 , A61K38/00 , C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070172830A1
公开(公告)日：2007-07-26
申请号：US10849979
申请日：2004-05-21
申请人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse
发明人： Steven Ruben , Kimberly Florence , Jian Ni , Craig Rosen , Kenneth Carter , Paul Moore , Henrik Olsen , Yanggu Shi , Paul Young , Ying-Fei Wei , Laurie Brewer , Daniel Soppet , David LaFleur , Gregory Endress , Reinhard Ebner , Charles Birse
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070020724A1
公开(公告)日：2007-01-25
申请号：US10886642
申请日：2004-07-09
申请人： Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
发明人： Steven Ruben , Jian Ni , Craig Rosen , Ying-Fei Wei , Paul Young , Kimberly Florence , Daniel Soppet , Laurie Brewer , Gregory Endress , Kenneth Carter , Michael Mucenski , Reinhard Ebner , David LaFleur , Henrik Olsen , Yanggu Shi , Paul Moore , George Komatsoulis
CPC分类号： C07K14/47
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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公开(公告)号：US20070014787A1
公开(公告)日：2007-01-18
申请号：US11375555
申请日：2006-03-15
申请人： Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
发明人： Steven Ruben , George Komatsoulis , D. Duan , Craig Rosen , Paul Moore , Yanggu Shi , David LaFleur , Reinhard Ebner , Henrik Olsen , Laurie Brewer , Kimberly Florence , Paul Young , Michael Mucenski , Gregory Endress , Daniel Soppet
IPC分类号： A61K39/395 , C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28
CPC分类号： C07K14/47 , A61K38/00 , C07K2319/30
摘要： The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
摘要翻译： 本发明涉及含有编码这些蛋白质的基因的编码区的新的人分泌蛋白和分离的核酸。 还提供了用于产生人分泌蛋白质的载体，宿主细胞，抗体和重组方法。 本发明还涉及用于诊断和治疗与这些新型人分泌蛋白相关的疾病，病症和/或病症的诊断和治疗方法。
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