公开(公告)号：US20240241078A1

公开(公告)日：2024-07-18

申请号：US18603999

申请日：2024-03-13

Applicant: DENSO CORPORATION

Inventor： Kazuhisa NAKAGAWA ,  Yuhei Shimizu ,  Daisuke Kobayashi ,  Masashi Suzuki ,  Akira Nukazuka ,  Teppei Sakai ,  Kei Hayakawa ,  Kazuhiko Kano ,  Mana Asano

IPC: G01N27/414 ,  G01N27/30

CPC classification number: G01N27/4141 ,  G01N27/301

Abstract: An ion sensor includes an ion detection element, a reference electrode that provides a reference point of a potential, and a solution in which an ion concentration can be changed in a sensing area of the ion detection element. The sensing area of the ion detection element is disposed in the solution. A method for detecting a target substance employs an ion sensor. The target substance bound to a label having a function of changing the amount of ions detectable by the ion sensor is introduced into the solution, and a change in the amount of ions is detected using the ion sensor.

公开(公告)号：US20240309439A1

公开(公告)日：2024-09-19

申请号：US18677551

申请日：2024-05-29

Applicant: Denso Corporation

Inventor： Mai NIIMOTO ,  Akira Nukazuka ,  Mana Asano ,  Kazuhisa Nakagawa ,  Kei Hayakawa

IPC: C12Q1/6851 ,  C12Q1/6806 ,  C12Q1/6876

CPC classification number: C12Q1/6851 ,  C12Q1/6876 ,  C12Q1/6806

Abstract: An analysis method detects a target substance using a binding substance. The binding substance includes: a single-stranded nucleic acid preparation having activity to bind to the target substance; and a complementary nucleic acid that forms a base pair with a 3′ terminal region of the single-stranded nucleic acid preparation when the single-stranded nucleic acid preparation is not bound to the target substance, and that dissociates from the 3′ terminal region when the single-stranded nucleic acid preparation is bound to the target substance.