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公开(公告)号:US20050095611A1
公开(公告)日:2005-05-05
申请号:US10836649
申请日:2004-04-30
申请人: Daniel Chan , Zhen Zhang , Jens Koopmann , Michael Goggins , C. White , Eric Fung , Xiao-Ying Meng
发明人: Daniel Chan , Zhen Zhang , Jens Koopmann , Michael Goggins , C. White , Eric Fung , Xiao-Ying Meng
IPC分类号: C12Q20060101 , C12Q1/68 , G01N33/574
CPC分类号: G01N33/57438 , C12Q1/6886 , C12Q2600/158
摘要: The present invention relates to a method of qualifying pancreatic cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject and (b) correlating the measurement with pancreatic cancer status. The invention further relates to kits for qualifying pancreatic cancer status in a subject.
摘要翻译: 本发明涉及一种在受试者中鉴定胰腺癌状态的方法,包括:(a)测量来自受试者的样品中所公开的生物标志物中的至少一种和(b)将测量与胰腺癌状态相关联。 本发明还涉及用于在受试者中鉴定胰腺癌状态的试剂盒。
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公开(公告)号:US20050059013A1
公开(公告)日:2005-03-17
申请号:US10635308
申请日:2003-08-05
申请人: Daniel Chan , Zhen Zhang , Eric Fung , Xiao-Ying Meng
发明人: Daniel Chan , Zhen Zhang , Eric Fung , Xiao-Ying Meng
IPC分类号: A61B20060101 , C07H21/02 , C07H21/04 , C07K14/81 , C12P19/34 , C12Q1/25 , C12Q1/68 , G01N20060101 , G01N30/72 , G01N30/96 , G01N33/48 , G01N33/52 , G01N33/574 , G06F19/00
CPC分类号: G01N33/543 , G01N33/57449 , Y10S435/807 , Y10S435/967 , Y10S435/973 , Y10S436/811 , Y10S436/813 , Y10S436/815 , Y10S436/824 , Y10S436/825 , Y10T436/24 , Y10T436/255
摘要: The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to kits for qualifying ovarian cancer status in a subject.
摘要翻译: 本发明涉及一种在受试者中鉴定卵巢癌状态的方法,包括:(a)测量来自受试者的样品中的至少一种生物标志物,和(b)将测量与卵巢癌状态相关联。 本发明还涉及用于在受试者中鉴定卵巢癌状态的试剂盒。
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公开(公告)号:US20070054329A1
公开(公告)日:2007-03-08
申请号:US11373833
申请日:2006-03-10
申请人: Eric Fung , Robert Bast , Daniel Chan , Jin Song , Valdimir Podust , Zhen Zhang
发明人: Eric Fung , Robert Bast , Daniel Chan , Jin Song , Valdimir Podust , Zhen Zhang
IPC分类号: G01N33/574
CPC分类号: G01N33/6851 , G01N33/57442 , G01N33/57449 , G01N33/68 , G01N33/74 , G01N2500/00
摘要: The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
摘要翻译: 本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地,已经发现,铁调素是卵巢癌和子宫内膜癌的生物标志物,并且一组生物标志物,包括铁调素,转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。
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公开(公告)号:US20070172902A1
公开(公告)日:2007-07-26
申请号:US11473280
申请日:2006-06-21
申请人: Zhen Zhang , Daniel Chan , Eric Fung , Zheng Wang , Fujun Zhang
发明人: Zhen Zhang , Daniel Chan , Eric Fung , Zheng Wang , Fujun Zhang
IPC分类号: G01N33/574 , G06F19/00
CPC分类号: G01N33/57449 , G01N2333/52
摘要: The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.
摘要翻译: 本发明提供了一种可用于鉴定患者卵巢癌状态的基于蛋白质的生物标志物。 特别地,本发明的生物标志物可用于将受试者样品分类为卵巢癌或非卵巢癌。 可通过SELDI质谱法检测生物标志物。
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公开(公告)号:US20050176011A1
公开(公告)日:2005-08-11
申请号:US10512731
申请日:2003-04-25
申请人: Daniel Chan , Jinong Li , Zhen Zhang
发明人: Daniel Chan , Jinong Li , Zhen Zhang
IPC分类号: C12Q1/68 , G01N33/00 , G01N33/574
CPC分类号: G01N33/6893 , G01N33/57434 , G01N33/57438 , G01N33/57488 , G01N33/6848
摘要: The present invention relates to a method of qualifying prostate cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject and (b) correlating the measurement with prostate cancer status. The invention further relates to kits for qualifying prostate cancer status in a subject.
摘要翻译: 本发明涉及一种在受试者中鉴定前列腺癌状态的方法,包括:(a)测量来自受试者的样品中所公开的生物标志物中的至少一种和(b)将测量与前列腺癌状态相关联。 本发明还涉及用于在受试者中鉴定前列腺癌状态的试剂盒。
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公开(公告)号:US20050170352A1
公开(公告)日:2005-08-04
申请号:US10506725
申请日:2003-03-06
申请人: Daniel Chan , Zhen Zhang , Jinong Li
发明人: Daniel Chan , Zhen Zhang , Jinong Li
IPC分类号: G01N33/574 , C12Q1/68
CPC分类号: G01N33/57415
摘要: The present invention relates to a method for identification of tmor biomarkers markers for breast cancer, with high specificity and sensitivity. Preferred methods of the invention include qualifying breast cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject; and (b) correlating the measurement with breast cancer status. The invention further relates to kits for qualifying breast cancer status in a subject.
摘要翻译: 本发明涉及一种具有高特异性和灵敏度的用于鉴定乳腺癌组织标记物的标记物的方法。 本发明的优选方法包括在受试者中确定乳腺癌状态,包括:(a)测量来自受试者的样品中所公开的生物标志物中的至少一种; 和(b)将测量与乳腺癌状态相关联。 本发明还涉及用于在受试者中鉴定乳腺癌状态的试剂盒。
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公开(公告)号:US20050214760A1
公开(公告)日:2005-09-29
申请号:US10500838
申请日:2003-01-07
申请人: Daniel Chan , Zhen Zhang , Alex Rai
发明人: Daniel Chan , Zhen Zhang , Alex Rai
IPC分类号: C12Q1/68 , G01N33/574
CPC分类号: C12Q1/6886 , G01N33/57449
摘要: New biomarkers are provided that are useful for detecting cancer in a patient sample, particularly ovarian cancer. In a preferred aspect, methods for qualifying ovarian cancer status in a subject are provided that comprises measuring at least one of Markers I through VII in a sample from the subject, and correlating the measurement with ovarian cancer status.
摘要翻译: 提供了新的生物标志物,其可用于检测患者样品中的癌症,特别是卵巢癌。 在一个优选的方面,提供了在受试者中鉴定卵巢癌状态的方法,其包括在受试者的样品中测量至少一种标志物I至VII,并将测量与卵巢癌状态相关联。
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公开(公告)号:US08621276B2
公开(公告)日:2013-12-31
申请号:US12970985
申请日:2010-12-17
申请人: Sarosh C. Havewala , Neal R. Christiansen , John D. Slingwine , Daniel Chan , Craig A. Barkhouse , Lane Haury , Kiran Kumar G. Bangalore , Thiago Sigrist
发明人: Sarosh C. Havewala , Neal R. Christiansen , John D. Slingwine , Daniel Chan , Craig A. Barkhouse , Lane Haury , Kiran Kumar G. Bangalore , Thiago Sigrist
IPC分类号: G06F11/00
CPC分类号: G06F11/0793 , G06F11/0727 , G06F11/0772 , G06F11/0775
摘要: Perceived corruptions encountered on file system volumes, and which cannot be initially remedied online, are processed to verify whether they are true, existing volume data structure corruptions or, alternatively, false positives. Upon the verification of one or more of a volume's corruptions, error scanning is performed to check for, and attempt to remedy online, all the existing corruptions on the volume. Subsequent to error scanning processing, if one or more verified corruptions continue to exist on a file system volume, at file system boot up time spot corruption correction is performed to attempt to remedy the existing, verified corruptions on the volume. Spot corruption correction is performed to attempt to correct verified data structure corruptions on a volume of the file system while the volume is maintained offline for the time necessary to attempt to correct its prior identified corruptions.
摘要翻译: 在文件系统卷上遇到的感知到的损坏,最初不能在线补救,将被处理,以验证它们是真实的,现有的卷数据结构损坏还是错误的。 在验证一个或多个卷的损坏后,执行错误扫描以检查并尝试在线补救卷上的所有现有损坏。 在错误扫描处理之后,如果在文件系统卷上继续存在一个或多个已验证的损坏,则在文件系统启动时执行斑点损坏修正,以尝试补救现有的已验证的卷上的损坏。 执行点腐败纠正,以在卷保持脱机的同时尝试更正其先前识别的损坏所需的时间,尝试纠正文件系统卷上的已验证数据结构损坏。
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公开(公告)号:USD643576S1
公开(公告)日:2011-08-16
申请号:US29367035
申请日:2010-08-02
申请人: Daniel Chan
设计人: Daniel Chan
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公开(公告)号:US08607099B2
公开(公告)日:2013-12-10
申请号:US12970948
申请日:2010-12-17
申请人: Sarosh C. Havewala , Neal R. Christiansen , John D. Slingwine , Craig A. Barkhouse , Daniel Chan
发明人: Sarosh C. Havewala , Neal R. Christiansen , John D. Slingwine , Craig A. Barkhouse , Daniel Chan
IPC分类号: G06F11/00
CPC分类号: G06F11/1435 , G06F11/0727 , G06F11/0793 , G06F2201/84
摘要: Data structure errors, or corruptions, identified during, e.g., normal computing device system processing, file system processing or user access processing, are verified prior to the file system identifying the error for offline correction or notifying the user or system administrator a data structure error exists. Identified data structure corruptions are verified while the file system volumes are maintained online and otherwise accessible to other processing tasks and user access. Verified data structure corruptions are logged for further corrective processing. Data structure corruptions that cannot be verified, i.e., false positives, are not further processed and are not identified to file system administrators or users as corruptions, freeing the file system to concentrate on normal processing and true, verifiable errors.
摘要翻译: 在文件系统识别用于离线校正的错误之前,验证在例如正常的计算设备系统处理,文件系统处理或用户访问处理期间识别的数据结构错误或损坏,或者通知用户或系统管理员数据结构错误 存在 在文件系统卷保持在线状态以及其他处理任务和用户访问权限的情况下,会验证已识别的数据结构损坏。 记录已验证的数据结构损坏以进一步纠正处理。 无法验证的数据结构损坏(即假阳性)不会进一步处理,并且不会将文件系统管理员或用户识别为损坏,从而释放文件系统以专注于正常处理和真实可验证的错误。
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