公开(公告)号：US20050214760A1

公开(公告)日：2005-09-29

申请号：US10500838

申请日：2003-01-07

申请人： Daniel Chan ,  Zhen Zhang ,  Alex Rai

发明人： Daniel Chan ,  Zhen Zhang ,  Alex Rai

IPC分类号： C12Q1/68 ,  G01N33/574

CPC分类号： C12Q1/6886 ,  G01N33/57449

摘要： New biomarkers are provided that are useful for detecting cancer in a patient sample, particularly ovarian cancer. In a preferred aspect, methods for qualifying ovarian cancer status in a subject are provided that comprises measuring at least one of Markers I through VII in a sample from the subject, and correlating the measurement with ovarian cancer status.

摘要翻译： 提供了新的生物标志物，其可用于检测患者样品中的癌症，特别是卵巢癌。 在一个优选的方面，提供了在受试者中鉴定卵巢癌状态的方法，其包括在受试者的样品中测量至少一种标志物I至VII，并将测量与卵巢癌状态相关联。

公开(公告)号：US20070172902A1

公开(公告)日：2007-07-26

申请号：US11473280

申请日：2006-06-21

申请人： Zhen Zhang ,  Daniel Chan ,  Eric Fung ,  Zheng Wang ,  Fujun Zhang

发明人： Zhen Zhang ,  Daniel Chan ,  Eric Fung ,  Zheng Wang ,  Fujun Zhang

IPC分类号： G01N33/574 ,  G06F19/00

CPC分类号： G01N33/57449 ,  G01N2333/52

摘要： The present invention provides a protein-based biomarker that is useful in qualifying ovarian cancer status in a patient. In particular, the biomarker of this invention is useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarker can be detected by SELDI mass spectrometry.

摘要翻译： 本发明提供了一种可用于鉴定患者卵巢癌状态的基于蛋白质的生物标志物。 特别地，本发明的生物标志物可用于将受试者样品分类为卵巢癌或非卵巢癌。 可通过SELDI质谱法检测生物标志物。

公开(公告)号：US20050170352A1

公开(公告)日：2005-08-04

申请号：US10506725

申请日：2003-03-06

申请人： Daniel Chan ,  Zhen Zhang ,  Jinong Li

发明人： Daniel Chan ,  Zhen Zhang ,  Jinong Li

IPC分类号： G01N33/574 ,  C12Q1/68

CPC分类号： G01N33/57415

摘要： The present invention relates to a method for identification of tmor biomarkers markers for breast cancer, with high specificity and sensitivity. Preferred methods of the invention include qualifying breast cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject; and (b) correlating the measurement with breast cancer status. The invention further relates to kits for qualifying breast cancer status in a subject.

摘要翻译： 本发明涉及一种具有高特异性和灵敏度的用于鉴定乳腺癌组织标记物的标记物的方法。 本发明的优选方法包括在受试者中确定乳腺癌状态，包括：（a）测量来自受试者的样品中所公开的生物标志物中的至少一种; 和（b）将测量与乳腺癌状态相关联。 本发明还涉及用于在受试者中鉴定乳腺癌状态的试剂盒。

公开(公告)号：US20070054329A1

公开(公告)日：2007-03-08

申请号：US11373833

申请日：2006-03-10

申请人： Eric Fung ,  Robert Bast ,  Daniel Chan ,  Jin Song ,  Valdimir Podust ,  Zhen Zhang

发明人： Eric Fung ,  Robert Bast ,  Daniel Chan ,  Jin Song ,  Valdimir Podust ,  Zhen Zhang

IPC分类号： G01N33/574

CPC分类号： G01N33/6851 ,  G01N33/57442 ,  G01N33/57449 ,  G01N33/68 ,  G01N33/74 ,  G01N2500/00

摘要： The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.

摘要翻译： 本发明提供了可用于鉴定卵巢癌状态以及患者中子宫内膜癌状态的基于蛋白质的生物标志物和生物标志物组合。 特别地，已经发现，铁调素是卵巢癌和子宫内膜癌的生物标志物，并且一组生物标志物，包括铁调素，转甲状腺素蛋白和任选的其他标记物可用于将受试者样品分类为卵巢癌或非卵巢癌。 生物标志物可以通过SELDI质谱检测。

公开(公告)号：US20050176011A1

公开(公告)日：2005-08-11

申请号：US10512731

申请日：2003-04-25

申请人： Daniel Chan ,  Jinong Li ,  Zhen Zhang

发明人： Daniel Chan ,  Jinong Li ,  Zhen Zhang

IPC分类号： C12Q1/68 ,  G01N33/00 ,  G01N33/574

CPC分类号： G01N33/6893 ,  G01N33/57434 ,  G01N33/57438 ,  G01N33/57488 ,  G01N33/6848

摘要： The present invention relates to a method of qualifying prostate cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject and (b) correlating the measurement with prostate cancer status. The invention further relates to kits for qualifying prostate cancer status in a subject.

摘要翻译： 本发明涉及一种在受试者中鉴定前列腺癌状态的方法，包括：（a）测量来自受试者的样品中所公开的生物标志物中的至少一种和（b）将测量与前列腺癌状态相关联。 本发明还涉及用于在受试者中鉴定前列腺癌状态的试剂盒。

公开(公告)号：US20050059013A1

公开(公告)日：2005-03-17

申请号：US10635308

申请日：2003-08-05

申请人： Daniel Chan ,  Zhen Zhang ,  Eric Fung ,  Xiao-Ying Meng

发明人： Daniel Chan ,  Zhen Zhang ,  Eric Fung ,  Xiao-Ying Meng

IPC分类号： A61B20060101 ,  C07H21/02 ,  C07H21/04 ,  C07K14/81 ,  C12P19/34 ,  C12Q1/25 ,  C12Q1/68 ,  G01N20060101 ,  G01N30/72 ,  G01N30/96 ,  G01N33/48 ,  G01N33/52 ,  G01N33/574 ,  G06F19/00

CPC分类号： G01N33/543 ,  G01N33/57449 ,  Y10S435/807 ,  Y10S435/967 ,  Y10S435/973 ,  Y10S436/811 ,  Y10S436/813 ,  Y10S436/815 ,  Y10S436/824 ,  Y10S436/825 ,  Y10T436/24 ,  Y10T436/255

摘要： The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the measurement with ovarian cancer status. The invention further relates to kits for qualifying ovarian cancer status in a subject.

摘要翻译： 本发明涉及一种在受试者中鉴定卵巢癌状态的方法，包括：（a）测量来自受试者的样品中的至少一种生物标志物，和（b）将测量与卵巢癌状态相关联。 本发明还涉及用于在受试者中鉴定卵巢癌状态的试剂盒。

公开(公告)号：US20050095611A1

公开(公告)日：2005-05-05

申请号：US10836649

申请日：2004-04-30

申请人： Daniel Chan ,  Zhen Zhang ,  Jens Koopmann ,  Michael Goggins ,  C. White ,  Eric Fung ,  Xiao-Ying Meng

发明人： Daniel Chan ,  Zhen Zhang ,  Jens Koopmann ,  Michael Goggins ,  C. White ,  Eric Fung ,  Xiao-Ying Meng

IPC分类号： C12Q20060101 ,  C12Q1/68 ,  G01N33/574

CPC分类号： G01N33/57438 ,  C12Q1/6886 ,  C12Q2600/158

摘要： The present invention relates to a method of qualifying pancreatic cancer status in a subject comprising: (a) measuring at least one of the disclosed biomarkers in a sample from the subject and (b) correlating the measurement with pancreatic cancer status. The invention further relates to kits for qualifying pancreatic cancer status in a subject.

摘要翻译： 本发明涉及一种在受试者中鉴定胰腺癌状态的方法，包括：（a）测量来自受试者的样品中所公开的生物标志物中的至少一种和（b）将测量与胰腺癌状态相关联。 本发明还涉及用于在受试者中鉴定胰腺癌状态的试剂盒。

公开(公告)号：US09099327B2

公开(公告)日：2015-08-04

申请号：US13568839

申请日：2012-08-07

申请人： Wilfried Haensch ,  Christian Lavoie ,  Christine Qiqing Ouyang ,  Xiaoyan Shao ,  Paul M. Solomon ,  Zhen Zhang ,  Bin Yang

发明人： Wilfried Haensch ,  Christian Lavoie ,  Christine Qiqing Ouyang ,  Xiaoyan Shao ,  Paul M. Solomon ,  Zhen Zhang ,  Bin Yang

IPC分类号： H01L29/06 ,  H01L21/8238 ,  H01L29/417

CPC分类号： H01L29/0673 ,  H01L21/823814 ,  H01L29/41791

摘要： A multigate structure which comprises a semiconductor substrate; an ultra-thin silicon or carbon bodies of less than 20 nanometers thick located on the substrate; an electrolessly deposited metallic layer selectively located on the side surfaces and top surfaces of the ultra-thin silicon or carbon bodies and selectively located on top of the multigate structures to make electrical contact with the ultra-thin silicon or carbon bodies and to minimize parasitic resistance, and wherein the ultra-thin silicon or carbon bodies and metallic layer located thereon form source and drain regions is provided along with a process to fabricate the structure.

摘要翻译： 一种多栅格结构，包括半导体衬底; 位于基板上的小于20纳米厚的超薄硅或碳体; 选择性地位于超薄硅或碳体的侧表面和顶表面上的无电沉积金属层，并且选择性地位于多结构结构的顶部上以与超薄硅或碳体电接触并最小化寄生电阻 并且其中位于其上的超薄硅或碳体和金属层形成源区和漏区以及制造该结构的工艺。

公开(公告)号：US20140375778A1

公开(公告)日：2014-12-25

申请号：US14354949

申请日：2011-12-21

申请人： Yongping Miao ,  Zhen Zhang ,  Junyu Luo ,  Weisong Gao

发明人： Yongping Miao ,  Zhen Zhang ,  Junyu Luo ,  Weisong Gao

IPC分类号： H04N13/04

CPC分类号： H04N13/302 ,  H04N13/31 ,  H04N13/327 ,  H04N13/366 ,  H04N13/373 ,  H04N13/376 ,  H04N13/38 ,  H04N13/383

摘要： Disclosed in the present application are a method and device for determining the position of a viewer and adjusting a viewing area, and a device for displaying three-dimensional video signals, such that the position of a viewer in front of an electronic device can be accurately determined and the viewing area can be adjusted according to the specific position, enabling the viewer to be unaware of any sudden viewing change when watching 3D signals. The method for determining the position of the viewer is applied in an electronic device comprising a display screen capable of displaying three-dimensional video signals. The viewing areas of the electronic device include a three-dimensional display area and a non-three-dimensional display area. The method comprises: acquiring the image in front of the electronic device; judging whether the image contains the face image of the viewer; if the image contains the face image, identifying at least one feature in the face image to determine the position of the viewer; according to the at least one feature, determining whether the viewing area of the viewer is a three-dimensional display area or a non-three-dimensional display area.

摘要翻译： 在本申请中公开了一种用于确定观看者的位置和调整观看区域的方法和装置，以及用于显示三维视频信号的装置，使得电子设备前面的观众的位置可以准确地 并且可以根据特定位置来调整观看区域，使得观看者在观看3D信号时不会意识到任何突然的观看变化。 用于确定观看者的位置的方法被应用于包括能够显示三维视频信号的显示屏的电子设备中。 电子设备的观看区域包括三维显示区域和非三维显示区域。 该方法包括：获取电子设备前面的图像; 判断图像是否包含观看者的脸部图像; 如果图像包含脸部图像，则识别脸部图像中的至少一个特征以确定观看者的位置; 根据至少一个特征，确定观看者的观看区域是三维显示区域还是非三维显示区域。

公开(公告)号：US08865556B2

公开(公告)日：2014-10-21

申请号：US13611893

申请日：2012-09-12

申请人： Joseph S. Newbury ,  Kenneth Parker Rodbell ,  Zhen Zhang ,  Yu Zhu

发明人： Joseph S. Newbury ,  Kenneth Parker Rodbell ,  Zhen Zhang ,  Yu Zhu

IPC分类号： H01L29/78 ,  H01L21/8238 ,  H01L21/02

CPC分类号： H01L21/28518 ,  H01L29/45 ,  H01L29/66628 ,  H01L29/66636 ,  H01L29/7848

摘要： Techniques for forming a smooth silicide without the use of a cap layer are provided. In one aspect, a FET device is provided. The FET device includes a SOI wafer having a SOI layer over a BOX and at least one active area formed in the wafer; a gate stack over a portion of the at least one active area which serves as a channel of the device; source and drain regions of the device adjacent to the gate stack, wherein the source and drain regions of the device include a semiconductor material selected from: silicon and silicon germanium; and silicide contacts to the source and drain regions of the device, wherein an interface is present between the silicide contacts and the semiconductor material, and wherein the interface has an interface roughness of less than about 5 nanometers.

摘要翻译： 提供了不使用盖层形成光滑硅化物的技术。 一方面，提供一种FET器件。 FET器件包括在BOX上具有SOI层的SOI晶片和形成在晶片中的至少一个有源区域; 所述至少一个有效区域的一部分上的栅极堆叠，其用作所述装置的通道; 源极和漏极区域，其中该器件的源极和漏极区域包括选自硅和硅锗的半导体材料; 并且硅化物接触到器件的源极和漏极区域，其中在硅化物触点和半导体材料之间存在界面，并且其中界面的界面粗糙度小于约5纳米。