ANTIMICROBIAL HYDROGELS, METHODS OF PREPARATION THEREOF, AND ARTICLES THEREFROM
    6.
    发明申请
    ANTIMICROBIAL HYDROGELS, METHODS OF PREPARATION THEREOF, AND ARTICLES THEREFROM 有权
    抗微生物水凝胶,其制备方法及其制品

    公开(公告)号:US20120231060A1

    公开(公告)日:2012-09-13

    申请号:US13213555

    申请日:2011-08-19

    摘要: A covalently crosslinked hydrogel comprises a) three or more divalent poly(alkylene oxide) chains P′ covalently linked at respective first end units to a branched first core group C′, b) three or more divalent poly(alkylene oxide) chains P″ covalently linked at respective first end units to a branched second core group C″, the chains P″ comprising respective second end units which are covalently linked to between 0% and 100% of respective second end units of chains P′ by divalent linking groups L″, and c) at least one pendant cationic block copolymer chain A′-B′. A′-B′ comprises i) a divalent block A′ comprising a poly(alkylene oxide) backbone chain having an end unit covalently linked to a second end unit of one of the chains P′ by a divalent linking group L′, and ii) a monovalent block B′ comprising a first repeat unit, the first repeat unit comprising a backbone carbonate group and a cationic side chain group.

    摘要翻译: 共价交联的水凝胶包含a)在相应的第一端单元共价连接到支化的第一核心基团C'上的三个或更多个二价聚(环氧烷)链P',b)共价地三个或更多个二价聚(环氧烷)链P' 在相应的第一末端单元连接到支化的第二核心基团C“,链P”包括各自的第二末端单元,其通过二价连接基团L“共价连接到链P'的相应的第二末端单元的0%和100%之间 ,和c)至少一个阳离子嵌段共聚物链A'-B'。 A'-B'包括:i)包含聚(环氧烷)主链的二价嵌段A',其具有通过二价连接基团L'与链P'之一共价连接的末端单元,ii )包含第一重复单元的单价嵌段B',所述​​第一重复单元包含骨架碳酸酯基团和阳离子侧链基团。

    Antimicrobial hydrogels, methods of preparation thereof, and articles therefrom
    7.
    发明授权
    Antimicrobial hydrogels, methods of preparation thereof, and articles therefrom 有权
    抗微生物水凝胶,其制备方法及其制品

    公开(公告)号:US08496946B2

    公开(公告)日:2013-07-30

    申请号:US13213555

    申请日:2011-08-19

    IPC分类号: A61K9/00

    摘要: A covalently crosslinked hydrogel comprises a) three or more divalent poly(alkylene oxide) chains P′ covalently linked at respective first end units to a branched first core group C′, b) three or more divalent poly(alkylene oxide) chains P″ covalently linked at respective first end units to a branched second core group C″, the chains P″ comprising respective second end units which are covalently linked to between 0% and 100% of respective second end units of chains P′ by divalent linking groups L″, and c) at least one pendant cationic block copolymer chain A′-B′. A′-B′ comprises i) a divalent block A′ comprising a poly(alkylene oxide) backbone chain having an end unit covalently linked to a second end unit of one of the chains P′ by a divalent linking group L′, and ii) a monovalent block B′ comprising a first repeat unit, the first repeat unit comprising a backbone carbonate group and a cationic side chain group.

    摘要翻译: 共价交联的水凝胶包含a)三个或更多个在相应的第一末端单元共价连接至支化的第一核心基团C'的二价聚(烯化氧)链P',b)三个或更多个二价聚(烯化氧)链P“ 在各个第一末端单元共价连接至支链第二核心基团C“,链P”包含通过二价连接共价连接到链P'的相应第二末端单元的0%至100%之间的相应第二端单元 基团L“,和c)至少一个侧挂阳离子嵌段共聚物链A'-B'。 A'-B'包括:i)包含聚(环氧烷)主链的二价嵌段A',其具有通过二价连接基团L'与链P'之一共价连接的末端单元,ii )包含第一重复单元的单价嵌段B',所述​​第一重复单元包含骨架碳酸酯基团和阳离子侧链基团。

    METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR
    8.
    发明申请
    METHODS OF RING OPENING POLYMERIZATION AND CATALYSTS THEREFOR 有权
    环形聚合方法及其催化剂

    公开(公告)号:US20120046437A1

    公开(公告)日:2012-02-23

    申请号:US12859336

    申请日:2010-08-19

    IPC分类号: C07D245/00 C08G63/08

    摘要: A salt catalyst comprises an ionic complex of i) a nitrogen base comprising one or more guanidine and/or amidine functional groups, and ii) an oxoacid comprising one or more active acid groups, the active acid groups independently comprising a carbonyl group (C═O), sulfoxide group (S═O), and/or a phosphonyl group (P═O) bonded to one or more active hydroxy groups; wherein a ratio of moles of the active hydroxy groups to moles of the guanidine and/or amidine functional groups is greater than 0 and less than 2.0. The salt catalysts are capable of catalyzing ring opening polymerization of cyclic carbonyl compounds.

    摘要翻译: 盐催化剂包含i)包含一个或多个胍和/或脒官能团的氮碱的离子络合物,和ii)包含一个或多个活性酸基团的含氧酸,所述活性酸基团独立地包含羰基(C = O),亚砜基(S = O)和/或与一个或多个活性羟基键合的膦酰基(P = O); 其中所述活性羟基的摩尔数与所述胍和/或脒官能团的摩尔数之比大于0且小于2.0。 盐催化剂能够催化环羰基化合物的开环聚合。

    Methods of ring opening polymerization and catalysts therefor
    9.
    发明授权
    Methods of ring opening polymerization and catalysts therefor 有权
    开环聚合方法及其催化剂

    公开(公告)号:US08507640B2

    公开(公告)日:2013-08-13

    申请号:US12859336

    申请日:2010-08-19

    IPC分类号: C07D245/00 C08G63/00

    摘要: A salt catalyst comprises an ionic complex of i) a nitrogen base comprising one or more guanidine and/or amidine functional groups, and ii) an oxoacid comprising one or more active acid groups, the active acid groups independently comprising a carbonyl group (C═O), sulfoxide group (S═O), and/or a phosphonyl group (P═O) bonded to one or more active hydroxy groups; wherein a ratio of moles of the active hydroxy groups to moles of the guanidine and/or amidine functional groups is greater than 0 and less than 2.0. The salt catalysts are capable of catalyzing ring opening polymerization of cyclic carbonyl compounds.

    摘要翻译: 盐催化剂包括i)包含一个或多个胍和/或脒官能团的氮碱的离子络合物,和ii)包含一个或多个活性酸基团的含氧酸,所述活性酸基团独立地包含羰基(C = O),亚砜基(S = O)和/或与一个或多个活性羟基键合的膦酰基(P = O); 其中所述活性羟基的摩尔数与所述胍和/或脒官能团的摩尔数之比大于0且小于2.0。 盐催化剂能够催化环羰基化合物的开环聚合。