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1.发明授权Method and apparatus for filtering suspension of medical and biological fluids or the like 有权用于过滤医疗和生物流体等的悬浮液的方法和装置公开(公告)号：US06491819B2
公开(公告)日：2002-12-10
申请号：US09954734
申请日：2001-09-18
IPC分类号： B01D6114
CPC分类号： B01D65/08 , A61M1/262 , A61M1/265 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M2202/0429 , A61M2202/0439 , A61M2205/3334 , B01D39/1692 , B01D61/147 , B01D61/22 , B01D63/16 , B01D69/02 , B01D2321/20 , B01D2321/2025 , B01D2321/2058 , B01D2321/2066 , A61M2202/0042 , A61M2202/0035
摘要： An apparatus is disclosed for separating a suspension comprising at least two types of particles which are differently sized or shaped and in which the first type of particle may be deformable at a relatively lower force or faster rate than the second type of particle. A housing is provided having a generally cylindrical inner surface in which is mounted a rotor having a generally cylindrical outer surface. The outer surface of the rotor is spaced from the inner surface of the housing to define a suspension processing gap. A filter membrane is provided on the surface of the rotor or the housing that has pores with substantially precisely dimensioned shapes and sizes to correspond substantially to the shape of the first type of particle, thus allowing passage of the first type of particle and blocking passage of the second type of particle. A suspension is directed into the processing gap for either a selected residence time in contact with the filter membrane and/or at a selected force.
摘要翻译： 公开了一种用于分离包含至少两种不同尺寸或形状的颗粒的悬浮液的装置，其中第一类型的颗粒可以以比第二类型的颗粒更低的力或更快的速率变形。 提供具有大致圆柱形内表面的壳体，其中安装有具有大致圆柱形外表面的转子。 转子的外表面与壳体的内表面间隔开以限定悬挂处理间隙。 在转子或壳体的表面上提供过滤膜，其具有基本上精确尺寸的形状和尺寸的孔，其基本上对应于第一类型的颗粒的形状，从而允许第一类型的颗粒和阻挡通道 第二种类型的粒子。 将悬浮液引导到处理间隙中以选择与过滤膜接触的停留时间和/或以选定的力。
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2.发明授权公开(公告)号：US06497821B1
公开(公告)日：2002-12-24
申请号：US09312883
申请日：1999-05-17
IPC分类号： B01D6100
CPC分类号： B01D65/08 , A61M1/262 , A61M1/265 , A61M1/34 , A61M1/3403 , A61M1/341 , A61M2202/0429 , A61M2202/0439 , A61M2205/3334 , B01D39/1692 , B01D61/147 , B01D61/22 , B01D63/16 , B01D69/02 , B01D2321/20 , B01D2321/2025 , B01D2321/2058 , B01D2321/2066 , A61M2202/0042 , A61M2202/0035
摘要： A method and apparatus for filtering suspensions of medical and biological fluids, one aspect of which is separating a suspension comprising at least two types of particles which are differently sized or shaped and in which the first type of particle may be deformable at a relatively lower force and/or faster rate than the second type of particle. A filter member is provided having substantially precisely dimensioned pore sizes, with the pores being dimensioned to allow passage of the first type of suspended particle without distortion or only minimal distortion and passage of the second type of particle only with substantial distortion. Because the filter membrane has precisely dimensioned pores, with spacing between the pores being maintained despite the smaller interval between the pores, the porosity of the membrane may be much greater than nominal pore size membranes, allowing faster filtration rates and/or smaller membranes for a given filtration rate, while reducing the exposure time of the cells within the shear environment, and consequently reducing particle damage. Various methods for preventing clogging of the membrane are also disclosed.
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公开(公告)号：US08485194B2
公开(公告)日：2013-07-16
申请号：US13550666
申请日：2012-07-17
IPC分类号： A61M11/00
CPC分类号： A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0493 , A61M16/0495 , A61M16/0666 , A61M16/0672 , A61M16/0816
摘要： An oral airway for insertion into a mouth and pharynx of a patient to provide a breathing pathway and for cooperating with either an anesthesia breathing connector, a suction tube, or a nasal cannula. The oral airway includes a first tubular member, a second tubular member disposed within the first tubular member, and a connector configured to securely attach to both the first tubular member and the second tubular member. The connector includes a first portion in fluid communication with the first tubular member and a second portion in fluid communication with the second tubular member.
摘要翻译： 用于插入患者口腔和咽部以提供呼吸通路并用于与麻醉呼吸连接器，抽吸管或鼻插管配合的口腔气道。 所述口腔气道包括第一管状构件，设置在所述第一管状构件内的第二管状构件和被构造成牢固地附接到所述第一管状构件和所述第二管状构件的连接器。 连接器包括与第一管状构件流体连通的第一部分和与第二管状构件流体连通的第二部分。
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公开(公告)号：USD680642S1
公开(公告)日：2013-04-23
申请号：US29415724
申请日：2012-03-13
申请人： Phillip B. Guerra , Paul R. Prince
设计人： Phillip B. Guerra , Paul R. Prince
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公开(公告)号：US06568938B1
公开(公告)日：2003-05-27
申请号：US09717586
申请日：2000-11-21
申请人： Paul R. Prince , Mary Von Lortz
发明人： Paul R. Prince , Mary Von Lortz
IPC分类号： G09B1100
摘要： A system for sketching, illustrating, drawing or painting likeness compositions such as canvas oil paintings from source images includes a set of increasing size reusable overlayable source image grids with image composition frames used with corresponding destination canvas grid patterns, allowing a consistent grid pattern for all canvas sizes by using predetermined grid dimensions for each canvas size. The image grid patterns may be affixed to clear plastic sheets or may be software-generated patterns. This combination greatly simplifies the use of grids in artwork and provides low-cost timesaving methods to draw accurate perspective. The system includes a unique canvas grid ruler for simplifying generation of canvas grid lines and in some embodiments canvases are pre-printed or backside-shadowed with appropriate canvas grid patterns and labels.
摘要翻译： 用于从源图像中绘制，绘制或绘制诸如帆布油画的相似组合的系统包括一组增加尺寸的可重复使用的可叠加源图像网格，其具有与相应的目的地画布网格图案一起使用的图像合成框架，从而允许所有的网格图案一致 通过使用每个画布大小的预定网格尺寸来绘制画布大小。 图像网格图案可以被固定到透明塑料片上，或者可以是软件生成的图案。 这种组合大大简化了艺术品中网格的使用，并提供了低成本的节省时间的方法来绘制准确的视角。 该系统包括用于简化画布网格线的生成的独特的画布网格标尺，并且在一些实施例中，使用适当的画布网格图案和标签预先打印或背面阴影画布。
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公开(公告)号：US5178603A
公开(公告)日：1993-01-12
申请号：US556778
申请日：1990-07-24
申请人： Paul R. Prince
发明人： Paul R. Prince
CPC分类号： A61M1/30 , A61M1/262 , A61M1/303 , A61M1/308 , A61M1/3621 , A61M1/3639 , A61M1/3656 , A61M1/3643 , A61M2205/3344 , A61M2205/3351 , A61M2205/3355 , A61M2205/702 , A61M2205/705
摘要： A method and system for adaptively controlled withdrawal/infusion of a fluid, such as blood, to or from a fluid source, such as a blood vessel. An adaptive flow rate limit is established and periodically adjusted during the course of withdrawal/infusion so as to maximize and optimize the withdrawal/infusion rate while, at the same time, providing for rapid corrective adjustments in flow rate responsive to early indications of flow disruption, such as occlusion or collapse of the blood vessel during blood withdrawal. The method and system of the invention is particularly applicable to automated apheresis systems.
摘要翻译： 用于自适应控制地将流体（例如血液）排出/输注到流体源（例如血管）或从流体源（例如血管）输入的方法和系统。 在抽出/输注过程中建立适应性流量限制并进行周期性调整，以便最大限度地提高和优化提取/输注速率，同时提供响应早期流量中断的快速流量校正调整 ，例如在抽血期间血管的闭塞或塌陷。 本发明的方法和系统特别适用于自动取样系统。
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公开(公告)号：US4062070A
公开(公告)日：1977-12-13
申请号：US728874
申请日：1976-10-01
申请人： Paul R. Prince
发明人： Paul R. Prince
CPC分类号： E03D9/00
摘要： A toilet bowl system with a floating and self-rinsing deflector for receiving and noiselessly dispersing urine into the water located in the bottom of said toilet bowl.
摘要翻译： 一种具有漂浮和自漂洗偏转器的马桶系统，用于接收并无噪声地将尿液分散在位于所述马桶的底部的水中。
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公开(公告)号：US20130014754A1
公开(公告)日：2013-01-17
申请号：US13550666
申请日：2012-07-17
申请人： Phillip Guerra , Paul R. Prince
发明人： Phillip Guerra , Paul R. Prince
CPC分类号： A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0493 , A61M16/0495 , A61M16/0666 , A61M16/0672 , A61M16/0816
摘要： An oral airway for insertion into a mouth and pharynx of a patient to provide a breathing pathway and for cooperating with either an anesthesia breathing connector, a suction tube, or a nasal cannula. The oral airway includes a first tubular member, a second tubular member disposed within the first tubular member, and a connector configured to securely attach to both the first tubular member and the second tubular member. The connector includes a first portion in fluid communication with the first tubular member and a second portion in fluid communication with the second tubular member.
摘要翻译： 用于插入患者口腔和咽部以提供呼吸通路并用于与麻醉呼吸连接器，抽吸管或鼻插管配合的口腔气道。 所述口腔气道包括第一管状构件，设置在所述第一管状构件内的第二管状构件和被构造成牢固地附接到所述第一管状构件和所述第二管状构件的连接器。 连接器包括与第一管状构件流体连通的第一部分和与第二管状构件流体连通的第二部分。
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公开(公告)号：US5200090A
公开(公告)日：1993-04-06
申请号：US769335
申请日：1991-10-01
申请人： Michael G. Ford , Paul R. Prince
发明人： Michael G. Ford , Paul R. Prince
CPC分类号： A61M1/3441 , A61M1/3451 , A61M5/16809 , G01G17/04 , A61M2205/3393 , A61M5/16845 , Y10S210/929
摘要： A system is provided for weighing and monitoring flow from multiple fluid sources into a flow system wherein incoming fluid is received in a weighing bag attached to a control system for monitoring the amount of fluid passed through the weighing bag and for preventing admission of air into the flow system. An alarm attached to the weighing bag warns when fluid in the weighing bag is approaching empty, so that the fluid in the weighing bag can be replenished from the fluid source before the weighing bag runs dry. If fluid in the weighing bag is not replenished, the system automatically shuts down.The fluid pump can be absolutely calibrated using the controlled admission of known amounts of fluid into the weighing bag so that the amount of fluid introduced into the flow system through the weighing bag can be calculated automatically.
摘要翻译： 提供了一种用于称重和监测从多个流体源流入流动系统的系统，其中进入的流体被接收在附接到控制系统的称重袋中，用于监测通过称重袋的流体的量并防止空气进入 流量系统 称重袋附近的报警器警告当称重袋中的液体接近空时，使得称重袋内的液体可以在称重袋运行干燥之前从流体源中补充。 如果称重袋中的液体未补充，系统将自动关闭。 流体泵可以使用已知量的流体进入称重袋进行绝对校准，从而可以自动计算通过称重袋引入流量系统的流量。
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公开(公告)号：US5069792A
公开(公告)日：1991-12-03
申请号：US551598
申请日：1990-07-10
摘要： An adaptive filter concentrate flow control system and method includes a filter system, a pumping system driving feed fluid, concentrate and filtrate flowing through the filter system and a flow control system controlling the pumping system to maintain optimum filtrate flow rates or minimum feed flow rates along a control surface in a three dimensional transmembrane pressure--feed fluid rate--filtrate flow rate space. Actual sensed operating point data is used to locate the control surface so as to assure an optimized filtrate flow rate or minimized feed flow rate at which reversible blocking of the membrane has begun to occur without irreversible blocking or plugging. The system is advantageously employed to control and maximize the flow of plasma in a plasmapheresis system or to minimize the rate at which blood is withdrawn from a donor and introduced into the system while achieving a fixed rate of plasma flow.
摘要翻译： 适应性过滤浓缩物流量控制系统和方法包括过滤系统，驱动进料流体的泵送系统，流过过滤系统的浓缩物和滤液以及控制泵送系统的流量控制系统，以保持最佳滤液流速或最小进料流速 三维跨膜压力进料流体速率 - 滤液流量空间中的控制表面。 实际检测到的工作点数据用于定位控制表面，以确保最佳滤液流速或最小化的进料流速，在此处开始膜的可逆阻塞而没有不可逆的阻塞或堵塞。 该系统有利地用于控制和最大化血浆置换系统中的血浆的流动，或者最小化血液从供体中取出并被引入系统中的速率，同时实现固定的血浆流速。
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