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    Methods and systems for blood flow measurement using doppler optical coherence tomography
    1.
    发明授权
    Methods and systems for blood flow measurement using doppler optical coherence tomography 有权
    使用多普勒光学相干断层扫描进行血流测量的方法和系统

    公开(公告)号：US08244334B2

    公开(公告)日：2012-08-14

    申请号：US12101006

    申请日：2008-04-10

    申请人： David Huang ,  Yimin Wang

    发明人： David Huang ,  Yimin Wang

    IPC分类号： A61B6/00

    CPC分类号： A61B3/102

    摘要： This invention provides methods for non-invasive, real-time measuring and/or monitoring of local blood flow in a subject. Methods of the invention generally include the steps of obtaining Doppler shift images of at least two planes intersecting blood vessels at the scanned location; determining Doppler angles using the Doppler shift images; and then using the Doppler angles thus determined together with the Doppler shift signals to arrive at a measure of the volumetric blood flow. Also provided are systems and software for performing the methods.

    摘要翻译： 本发明提供了用于非侵入性，实时测量和/或监测受试者中局部血流的方法。 本发明的方法通常包括以下步骤：在扫描位置处获得与血管相交的至少两个平面的多普勒频移图像; 使用多普勒频移图像确定多普勒角度; 然后使用与多普勒频移信号一起确定的多普勒角度来达到体积血流量的量度。 还提供了用于执行方法的系统和软件。

    METHODS AND SYSTEMS FOR BLOOD FLOW MEASUREMENT USING DOPPLER OPTICAL COHERENCE TOMOGRAPHY
    2.
    发明申请
    METHODS AND SYSTEMS FOR BLOOD FLOW MEASUREMENT USING DOPPLER OPTICAL COHERENCE TOMOGRAPHY 有权
    使用多普勒光学相干计算血液流量测量的方法和系统

    公开(公告)号：US20090005691A1

    公开(公告)日：2009-01-01

    申请号：US12101006

    申请日：2008-04-10

    申请人： David Huang ,  Yimin Wang

    发明人： David Huang ,  Yimin Wang

    IPC分类号： A61B3/10 ,  A61B5/026

    CPC分类号： A61B3/102

    摘要： This invention provides methods for non-invasive, real-time measuring and/or monitoring of local blood flow in a subject. Methods of the invention generally include the steps of obtaining Doppler shift images of at least two planes intersecting blood vessels at the scanned location; determining Doppler angles using the Doppler shift images; and then using the Doppler angles thus determined together with the Doppler shift signals to arrive at a measure of the volumetric blood flow. Also provided are systems and software for performing the methods.

    摘要翻译： 本发明提供了用于非侵入性，实时测量和/或监测受试者中局部血流的方法。 本发明的方法通常包括以下步骤：在扫描位置处获得与血管相交的至少两个平面的多普勒频移图像; 使用多普勒频移图像确定多普勒角度; 然后使用与多普勒频移信号一起确定的多普勒角度来达到体积血流量的量度。 还提供了用于执行方法的系统和软件。

    SYSTEMS AND METHODS OF GLUACOMA DIAGNOSIS BASED ON FREQUENCY ANALYSIS OF INNER RETINAL SURFACE PROFILE MEASURED BY OPTICAL COHERENCE TOMOGRAPHY
    8.
    发明申请
    SYSTEMS AND METHODS OF GLUACOMA DIAGNOSIS BASED ON FREQUENCY ANALYSIS OF INNER RETINAL SURFACE PROFILE MEASURED BY OPTICAL COHERENCE TOMOGRAPHY 有权
    基于通过光学相干测量法测量的内膜表面轮廓的频率分析的GLUACOMA诊断系统和方法

    公开(公告)号：US20170055829A1

    公开(公告)日：2017-03-02

    申请号：US15253597

    申请日：2016-08-31

    申请人： Ou Tan ,  David Huang

    发明人： Ou Tan ,  David Huang

    IPC分类号： A61B3/12 ,  A61B3/10 ,  A61B3/00

    CPC分类号： A61B3/1225 ,  A61B3/0025 ,  A61B3/102 ,  G06T7/136 ,  G06T2207/30041

    摘要： A method for detecting glaucoma in a subject based on spatial frequency analysis of the inner limiting membrane (ILM) as obtained from optical coherence tomography (OCT) image data is disclosed. Based on the spatial frequency content of the analyzed ILM profile, a quantity called the Retinal surface contour variability (RSCV) is calculated and the presence or absence of a glaucoma condition is determined based on the RSCV magnitude.

    摘要翻译： 公开了一种基于从光学相干断层摄影（OCT）图像数据获得的内部限制膜（ILM）的空间频率分析来检测受试者中的青光眼的方法。 基于所分析的ILM谱的空间频率含量，计算称为视网膜表面轮廓变异性（RSCV）的量，并且基于RSCV幅度确定青光眼状况的存在或不存在。

    METHODS OF MEASURING TOTAL RETINAL BLOOD FLOW USING EN FACE DOPPLER OCT
    9.
    发明申请
    METHODS OF MEASURING TOTAL RETINAL BLOOD FLOW USING EN FACE DOPPLER OCT 审中-公开
    使用表面多普勒OCT测量总体血液流量的方法

    公开(公告)号：US20160287071A1

    公开(公告)日：2016-10-06

    申请号：US15089803

    申请日：2016-04-04

    申请人： Ou Tan ,  David Huang

    发明人： Ou Tan ,  David Huang

    IPC分类号： A61B3/12 ,  G06T5/00 ,  G06T7/00 ,  A61B3/10 ,  A61B3/00

    CPC分类号： A61B3/1233 ,  A61B3/0025 ,  A61B3/102 ,  A61B3/1241 ,  A61B5/7203 ,  A61B6/5258 ,  G06K9/0061 ,  G06K9/52 ,  G06K2209/05 ,  G06T7/0012 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2207/30104

    摘要： Methods of performing en face Doppler total retinal blood flow measurement are disclosed. The methods involve obtaining a set of structural OCT scans; calculating a noise-reduced set of Doppler phase shift images by dividing the full spectrum OCT fringe data into a set of narrower filtered frequency bands for phase shift calculation; removing bulk motion along a depth direction; detecting retinal vessels in the set of images; applying a phase unwrapping algorithm to the images; classifying the vessels as veins and arteries; and calculating total retinal blood flow based on that classification.

    摘要翻译： 公开了执行面部多普勒总视网膜血流量测量的方法。 该方法涉及获得一组结构OCT扫描; 通过将全谱OCT边缘数据划分成一组较窄的滤波频带以进行相移计算，来计算多普勒相移图像的噪声降低集合; 沿深度方向去除大量运动; 检测该组图像中的视网膜血管; 对图像应用相位解包算法; 将血管分类为静脉和动脉; 并根据该分类计算总视网膜血流量。

    Heat-Dissipating Structure for an LED Lamp
    10.
    发明申请
    Heat-Dissipating Structure for an LED Lamp 有权
    LED灯泡散热结构

    公开(公告)号：US20140063806A1

    公开(公告)日：2014-03-06

    申请号：US13596133

    申请日：2012-08-28

    申请人： David Huang

    发明人： David Huang

    IPC分类号： F21V29/00

    CPC分类号： F21V29/507 ,  F21K9/00 ,  F21V19/0055 ,  F21V23/023 ,  F21V29/83 ,  F21Y2103/33 ,  F21Y2115/10

    摘要： A heat-dissipating structure for LED lamp has a lamp cover, and a power conversion device and a ceramic substrate mounted inside the lamp cover. The lamp cover has multiple heat-dissipating holes and multiple mounting ears. Each mounting ear is formed on an edge of one of the heat-dissipating holes and is bent inwardly with the heat-dissipating hole uncovered. The ceramic substrate is mounted on the mounting ears. The ceramic substrate has multiple LEDs mounted thereon, absorbs heat generated when the LEDs emit light and conducts the heat to the lamp cover through the mounting ears. The heat generated when the LEDs are lit and the power conversion converts a mains power is transferred to a heat convection space between the ceramic substrate and the lamp cover, and is further dissipated to an ambient environment, thereby achieving fast heat dissipation and a light LED lamp without additional heat sink thereon.

    摘要翻译： 用于LED灯的散热结构具有灯罩，安装在灯罩内部的电力转换装置和陶瓷基板。 灯罩有多个散热孔和多个安装耳。 每个安装耳形成在一个散热孔的边缘上，并且在散热孔未被覆盖的同时向内弯曲。 陶瓷基板安装在安装耳上。 陶瓷基板上安装有多个LED，吸收当LED发光时产生的热量，并通过安装耳将热量传导到灯罩。 当LED点亮并且功率转换转换为主电源时产生的热量被传递到陶瓷基板和灯罩之间的热对流空间，并且进一步消散到周围环境，从而实现快速散热，并且将LED 灯，其上没有额外的散热器。