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    anti-parasitic compositions
    1.
    发明申请
    anti-parasitic compositions 审中-公开
    抗寄生物组合物

    公开(公告)号：US20100015233A1

    公开(公告)日：2010-01-21

    申请号：US12309295

    申请日：2007-06-29

    申请人： David John Duncalf ,  Asha Hassan Essa ,  Alison Jayne Foster ,  James Long ,  Steven Paul Rannard ,  Dong Wang

    发明人： David John Duncalf ,  Asha Hassan Essa ,  Alison Jayne Foster ,  James Long ,  Steven Paul Rannard ,  Dong Wang

    IPC分类号： A61K9/14

    CPC分类号： A61K9/1617 ,  A01N25/04 ,  A61K9/10 ,  A61K9/1635 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/19 ,  A61K31/167 ,  Y02A50/411 ,  A01N43/54 ,  A01N53/00 ,  A01N31/16 ,  A01N37/18

    摘要： The present invention relates to nanodisperse antiparasitics and provides a composition comprising at least one water insoluble anti-parasitic drug and a water-soluble carrier material, wherein the water-insoluble anti-parasitic drug (preferably an Artemisinin-type drug or a quinine type drug) is dispersed through the carrier material in nano-disperse form having a peak diameter of the nano-disperse form below 1000 nm. The invention further provides an aqueous dispersion of a water insoluble anti-parasitic drug and a water-soluble carrier material, wherein the anti-parasitic drug is in nano-disperse form having a peak diameter of the nano-disperse form below 1000 nm, the invention further subsists in a process for preparing an anti-parasitic composition comprising a water insoluble anti-parasitic agent and a water-soluble carrier, which comprises the steps of either: a) providing an emulsion comprising a solution of the anti-parasitic agent in a water-immiscible solvent for the same, and an aqueous solution of the carrier, or providing a mixture comprising at least one non-aqueous solvent optional water a water-soluble carrier material soluble in the mixture and a water-insoluble anti-parasitic agent soluble in the mixture, and, b) drying the emulsion (preferably by spray drying) to remove water and the water-immiscible solvent to obtain a substantially solvent-free nano-dispersion of the anti-parasitic agent in the carrier.

    摘要翻译： 本发明涉及纳米分散抗寄生虫药，并且提供包含至少一种水不溶性抗寄生虫药物和水溶性载体材料的组合物，其中所述水不溶性抗寄生虫药物（优选青蒿素型药物或奎宁型药物 ）以纳米分散形式的峰值直径低于1000nm的纳米分散形式分散在载体材料中。 本发明还提供了水不溶性抗寄生虫药物和水溶性载体材料的水性分散体，其中所述抗寄生虫药物为纳米分散形式，其纳米分散体形式的峰值直径低于1000nm， 本发明进一步存在于制备包含水不溶性抗寄生虫剂和水溶性载体的抗寄生物组合物的方法中，其包括以下步骤：a）提供包含抗寄生虫剂溶液的乳液 或与提供包含至少一种非水溶剂任选的水的混合物，可溶于该混合物的水溶性载体材料和水不溶性抗寄生剂 可溶于该混合物，和b）干燥乳液（优选通过喷雾干燥）以除去水和与水不混溶的溶剂，以获得基本上无溶剂的防虫剂纳米分散体 tic代理在承运人。

    Biocidal compositions
    10.
    发明申请
    Biocidal compositions 审中-公开
    杀生物组合物

    公开(公告)号：US20090239749A1

    公开(公告)日：2009-09-24

    申请号：US12309293

    申请日：2007-06-29

    申请人： David John Duncalf ,  Alison Jayne Foster ,  James Long ,  Steven Paul Rannard ,  Dong Wang

    发明人： David John Duncalf ,  Alison Jayne Foster ,  James Long ,  Steven Paul Rannard ,  Dong Wang

    IPC分类号： A01N25/14 ,  A01N25/08 ,  A01P21/00

    CPC分类号： A61K9/1617 ,  A01N25/04 ,  A61K9/10 ,  A61K9/1635 ,  A61K9/1641 ,  A61K9/1652 ,  A61K9/19 ,  A61K31/167 ,  Y02A50/411 ,  A01N43/54 ,  A01N53/00 ,  A01N31/16 ,  A01N37/18

    摘要： The invention provides a solvent-free biocidal composition of improved efficacy comprising at least one water insoluble biocide (preferably a herbicide) and a water-soluble carrier material, wherein the water-insoluble biocide is dispersed through the carrier material in nano-disperse form having a peak diameter of the nano-disperse form below 1000 nm. The invention also provides a process which comprises spray drying a solution of the biocide and a solution of a water-soluble carrier to obtain a solvent free dispersion of the biocide in the carrier, which, when dissolved in water, produces a nano-disperse biocide. The invention also provides an aqueous dispersion of a water insoluble biocide and a water-soluble carrier obtained by the dispersion of the composition of the solvent free composition in water.

    摘要翻译： 本发明提供了一种改进功效的无溶剂杀生物组合物，其包含至少一种不溶于水的杀生物剂（优选除草剂）和水溶性载体材料，其中所述水不溶性杀生物剂通过载体材料以纳米分散形式分散， 纳米分散体的峰值直径低于1000nm。 本发明还提供了一种方法，其包括喷雾干燥杀生物剂的溶液和水溶性载体的溶液，以获得载体中无杀菌剂的无溶剂分散体，当溶解在水中时，其产生纳米分散杀生物剂 。 本发明还提供了通过将无溶剂组合物的组合物分散在水中而获得的水不溶性杀生物剂和水溶性载体的水分散体。