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32 条记录 (耗时 0.042 秒)

    Automated Multi-purpose Alert System with sensory interrupts
    3.
    发明申请
    Automated Multi-purpose Alert System with sensory interrupts 有权
    具有感官中断功能的自动多用途警报系统

    公开(公告)号：US20080186199A1

    公开(公告)日：2008-08-07

    申请号：US12025840

    申请日：2008-02-05

    申请人： David Lynn ,  Barry Lynn

    发明人： David Lynn ,  Barry Lynn

    IPC分类号： G05B19/02

    CPC分类号： H04M1/0291 ,  H04M1/2474 ,  H04M1/57 ,  H04M11/025 ,  H04M2250/02

    摘要： The present invention is an alert system and apparatus that interrupts the operation of sound producing and video display entertainment and communication devices and replaces the signals with an audible verbal annunciation and text message that overlays on the video displayed and initiates an alerting device or devices in connection with attracting the attention of hearing and/or visually impaired persons, persons who are not in close proximity to the area relating to the alert or by person who desire to be alerted by these mechanism.

    摘要翻译： 本发明是一种警报系统和装置，其中断声音产生和视频显示娱乐和通信设备的操作，并且以显示的视频覆盖的可听到的口头通告和文本消息替换信号，并且发起连接中的告警设备 引起听力和/或视力障碍者的注意，不紧密接近与警报有关的区域的人或希望被这些机制警告的人的注意力。

    Methods and products related to the intracellular delivery of polysaccharides
    5.
    发明申请
    Methods and products related to the intracellular delivery of polysaccharides 审中-公开
    与多糖细胞内转运相关的方法和产品

    公开(公告)号：US20060083711A1

    公开(公告)日：2006-04-20

    申请号：US11107360

    申请日：2005-04-15

    申请人： David Berry ,  Daniel Anderson ,  David Lynn ,  Ram Sasisekharan ,  Robert Langer

    发明人： David Berry ,  Daniel Anderson ,  David Lynn ,  Ram Sasisekharan ,  Robert Langer

    IPC分类号： A61K31/785 ,  A61K31/737 ,  A61K31/727

    CPC分类号： A61K45/06 ,  A61K31/726 ,  A61K31/727 ,  A61K31/737 ,  A61K31/785 ,  A61K47/593 ,  A61K2300/00

    摘要： The invention relates, in part, to methods and compositions for the intracellular delivery of polysaccharides. In particular, the methods and compositions relate to the intracellular delivery of glycosaminoglycans, such as heparin. The invention in other aspects relates to the use of glycosaminoglycans for the treatment of proliferative disorders, such as cancer. The invention is still other aspects relates to improving cell viability. The invention also relates to the delivery of polysaccharides while avoiding unwanted effects of the polysaccharides. For example, heparin can be delivered while avoiding its anticoagulant effects.

    摘要翻译： 本发明部分地涉及多糖的细胞内递送的方法和组合物。 特别地，所述方法和组合物涉及糖胺聚糖如肝素的细胞内递送。 本发明在其它方面涉及使用糖胺聚糖来治疗增殖性疾病如癌症。 本发明还涉及提高细胞活力的其它方面。 本发明还涉及多糖的递送，同时避免多糖的不期望的影响。 例如，可以输送肝素同时避免其抗凝血作用。

    pH triggerable polymeric particles
    6.
    发明申请
    pH triggerable polymeric particles 有权
    pH可触发聚合物颗粒

    公开(公告)号：US20050244504A1

    公开(公告)日：2005-11-03

    申请号：US11002542

    申请日：2004-12-02

    申请人： Steven Little ,  David Lynn ,  Daniel Anderson ,  Robert Langer

    发明人： Steven Little ,  David Lynn ,  Daniel Anderson ,  Robert Langer

    IPC分类号： A61K9/127 ,  A61K9/14 ,  A61K9/16 ,  A61K48/00 ,  C12N5/08 ,  C12N15/87 ,  C12N15/88

    CPC分类号： A61K9/1617 ,  A61K9/1623 ,  A61K9/1647 ,  A61K9/1658

    摘要： A drug delivery system comprising pH triggerable particles is described. The pH triggerable particles comprise and agent(s) to be delivered, which is encapsulated in a matrix comprising a pH trigger agent and a polymer. Agents including nucleic acids may be delivered intracellularly using the inventive pH triggerable particles. Upon exposure to an acidic environment such as the endosome or phagosome of a cell, the particles dissolve or disrupt due to protonation or an increase in solubility of the pH triggering agent. Pharmaceutical compositions and methods of preparing and administering these particles are also described. These particles may be particularly useful in genetic vaccination.

    摘要翻译： 描述了包含pH可触发颗粒的药物递送系统。 pH可触发颗粒包含待运送的试剂，其被包封在包含pH触发剂和聚合物的基质中。 包含核酸的试剂可以使用本发明的pH可触发颗粒在细胞内递送。 当暴露于诸如细胞的内体或吞噬体的酸性环境中时，由于质子化或pH引发剂的溶解度的增加，颗粒溶解或破坏。 还描述了制备和施用这些颗粒的药物组合物和方法。 这些颗粒在基因疫苗接种中可能特别有用。

    Protective Mesh Array for Use Within an Electrical Network
    7.
    发明公开
    Protective Mesh Array for Use Within an Electrical Network 审中-公开

    公开(公告)号：US20230318285A1

    公开(公告)日：2023-10-05

    申请号：US17803597

    申请日：2020-03-05

    申请人： David Lynn

    发明人： David Lynn

    IPC分类号： H02H7/28 ,  H05K7/02

    CPC分类号： H02H7/28 ,  H05K7/02

    摘要： A protective mesh system for distributing electrical power. The protective mesh system may include a body that supports and positions a protective mesh within its outer edges. The protective mesh may be of a single polarity and includes conductors and circuit opening devices. The protective mesh may provide for connecting to one or more power devices. One or more connectors may be electrically connected to the protective mesh and positioned along one or more of the edges of the body. The connectors may provide for connecting to an external power source.

    Magnetically-Controlled Connectors and Methods of Use
    8.
    发明申请
    Magnetically-Controlled Connectors and Methods of Use 审中-公开

    公开(公告)号：US20180195543A1

    公开(公告)日：2018-07-12

    申请号：US15401868

    申请日：2017-01-09

    申请人： David Lynn

    发明人： David Lynn

    IPC分类号： F16B5/06

    CPC分类号： F16B5/0635 ,  H02S20/00 ,  H02S40/30

    摘要： A magnetically-controlled connector for attaching a panel to a support member. The connector is configurable between locked and unlocked positions. In the locked position, an arm extends outward to engage with an exterior support member. In the unlocked position, the arm is retracted inward and is disengaged from the support member. The connector is configured to be movable between the positions using a magnetic actuator that is selectively moved into and out of proximity of the connector.

    Belt monitoring systems and methods
    9.
    发明授权
    Belt monitoring systems and methods 有权
    皮带监测系统和方法

    公开(公告)号：US08312987B2

    公开(公告)日：2012-11-20

    申请号：US12009097

    申请日：2008-01-16

    申请人： David Lynn ,  Graeme Knox ,  Carl Wacker ,  Ralph Moffett ,  William Stewart ,  Idir Boudaoud ,  Alan Kenneth McCall ,  Dave Hanes

    发明人： David Lynn ,  Graeme Knox ,  Carl Wacker ,  Ralph Moffett ,  William Stewart ,  Idir Boudaoud ,  Alan Kenneth McCall ,  Dave Hanes

    IPC分类号： F16G1/00 ,  F16G5/00 ,  F16G1/04 ,  F16G1/28 ,  G01M15/00

    CPC分类号： B65G43/02 ,  G01M13/023

    摘要： A belt monitoring system employs a belt having at least one reinforcement member made from a conductive reinforcement material. A belt monitor is disposed in conjunction with the belt. The belt monitor comprises a field inductor excited by an applied signal. An electrical characteristic of at least a portion of the field inductor as influenced by changes in the electrical properties of the conductive reinforcement member is monitored in order to determine a physical condition of the conductive reinforcement member and thereby monitor a physical characteristic of the belt. This monitoring may be carried out by a sense inductor disposed adjacent or in conjunction with the field inductor.

    摘要翻译： 皮带监测系统采用具有由导电增强材料制成的至少一个增强部件的皮带。 皮带显示器与皮带一起配置。 带式监视器包括由施加的信号激励的场感应电感。 为了确定导电加强件的物理状态，并且由此监测皮带的物理特性，监测场感应器的至少一部分的电特性，这受到导电加强件的电性能变化的影响。 该监视可以由与场感应器相邻或结合设置的感测电感器来执行。

    Belt monitoring systems and methods
    10.
    发明申请
    Belt monitoring systems and methods 有权
    皮带监测系统和方法

    公开(公告)号：US20090178902A1

    公开(公告)日：2009-07-16

    申请号：US12009097

    申请日：2008-01-16

    申请人： David Lynn ,  Graeme Knox ,  Carl Wacker ,  Ralph Moffett ,  William Stewart ,  Idir Boudaoud ,  Alan Kenneth McCall ,  Dave Hanes

    发明人： David Lynn ,  Graeme Knox ,  Carl Wacker ,  Ralph Moffett ,  William Stewart ,  Idir Boudaoud ,  Alan Kenneth McCall ,  Dave Hanes

    IPC分类号： B65G43/02

    CPC分类号： B65G43/02 ,  G01M13/023

    摘要： A belt monitoring system employs a belt having at least one reinforcement member made from a conductive reinforcement material. A belt monitor is disposed in conjunction with the belt. The belt monitor comprises a field inductor excited by an applied signal. An electrical characteristic of at least a portion of the field inductor as influenced by changes in the electrical properties of the conductive reinforcement member is monitored in order to determine a physical condition of the conductive reinforcement member and thereby monitor a physical characteristic of the belt. This monitoring may be carried out by a sense inductor disposed adjacent or in conjunction with the field inductor.

    摘要翻译： 皮带监测系统采用具有由导电增强材料制成的至少一个增强部件的皮带。 皮带显示器与皮带一起配置。 带式监视器包括由施加的信号激励的场感应电感。 为了确定导电加强件的物理状态，并且由此监测皮带的物理特性，监测场感应器的至少一部分的电特性，这受到导电加强件的电性能变化的影响。 该监视可以由与场感应器相邻或结合设置的感测电感器来执行。