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1.发明申请Fluid transfer assembly for pharmaceutical delivery system and method for using same 失效用于药物输送系统的流体输送组件及其使用方法公开(公告)号：US20070078428A1
公开(公告)日：2007-04-05
申请号：US11197439
申请日：2005-08-05
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2055
摘要： The present invention provides a transfer assembly for transferring a fluid between a vessel and a vial and a method for using same. The vial may be a maximum recovery vial. The vessel has a body with an open end and a slidable piston positioned within the body through the open end. The maximum recovery vial has an inner chamber with an open end and a closed end and a penetrable seal covering the open end of the inner chamber. The transfer assembly includes a housing having first and second open ends and a bore extending between the first and second open ends. The housing is connectable to the piston. The transfer assembly also includes a conduit having first and second ends and first and second apertures adjacent to the first and second ends, respectively. The conduit is longitudinally slidable within the bore between a retracted position in which the first aperture is positioned within at least one of the housing and the piston when the housing is connected to the piston, and an activated position in which the first aperture protrudes through the piston into the body of the vessel when the housing is connected to the piston. The transfer assembly also includes a vial socket assembly having a vial socket and a hollow piercing member. The vial socket is sized and shaped for receiving and engaging at least a portion of the maximum recovery vial including the penetrable seal. The hollow piercing member has a first open end in fluid communication with the conduit and a second open end for piercing the penetrable seal of the maximum recovery vial. The hollow piercing member is sized to extend substantially the full length of the inner chamber of the maximum recovery vial when the maximum recovery vial is fully engaged in the vial socket. The vial socket assembly is moveable longitudinally relative to the housing in concert with the conduit.
摘要翻译： 本发明提供一种用于在容器和小瓶之间传送流体的转移组件及其使用方法。 小瓶可以是最大回收小瓶。 容器具有开口端的本体和通过开口端定位在体内的可滑动活塞。 最大回收小瓶具有内室，其具有开口端和封闭端以及覆盖内室开口端的可穿透密封件。 传送组件包括具有第一和第二开口端的壳体和在第一和第二开口端之间延伸的孔。 外壳可连接到活塞。 传送组件还包括分别具有第一和第二端以及与第一和第二端相邻的第一和第二孔的导管。 所述管道可在所述孔内在缩回位置之间纵向滑动，在所述缩回位置中，当所述壳体连接到所述活塞时，所述第一孔被定位在所述壳体和所述活塞中的至少一个中;以及启动位置， 当壳体连接到活塞时，活塞进入容器的主体。 传送组件还包括具有小瓶插座和中空穿刺构件的小瓶插座组件。 小瓶插座的尺寸和形状适于接收和接合包括可穿透密封件的最大回收小瓶的至少一部分。 空心刺穿构件具有与导管流体连通的第一开口端和用于刺穿最大回收小瓶的可穿透密封件的第二开口端。 当最大回收小瓶完全接合在小瓶插座中时，中空穿刺构件的尺寸被设计成基本上延伸最大回收小瓶的内室的整个长度。 小瓶插座组件可以与导管一致地相对于壳体纵向移动。
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2.发明申请Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge 有权用于将容纳第一物质的小瓶的内容物与存储在筒中的第二物质混合的重构系统公开(公告)号：US20080172001A1
公开(公告)日：2008-07-17
申请号：US11974737
申请日：2007-10-16
IPC分类号： A61M5/00
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2065
摘要： A transfer assembly for transfering a fluid to a vial, admixing the same and then returning the fluid to a cartridge, the transfer assembly having a vial gripper located at a first end and a cartridge holder at the second end of an elongated outer housing, a fluid passageway extending between the vial gripper and the cartridge holder with piercing elements being located at respective ends of the fluid passageway. In a preferred embodiment, an adaptor is mounted on the end of the outer housing where the cartridge holder is situated. The adaptor may move from a retracted to an extended position wherein it will surround the needle.
摘要翻译： 一种转移组件，用于将流体转移到小瓶中，将其混合，然后将流体返回到药筒，转移组件具有位于第一端的小瓶夹持器和位于细长外壳体的第二端处的药筒保持器， 流体通道在小瓶夹持器和药筒保持器之间延伸，穿刺元件位于流体通道的相应端部处。 在优选实施例中，适配器安装在外壳的其中盒保持器所在的端部。 适配器可以从缩回移动到延伸位置，其中它将围绕针。
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公开(公告)号：US20100258213A1
公开(公告)日：2010-10-14
申请号：US12456101
申请日：2009-06-10
CPC分类号： A61J1/2089
摘要： The transfer device for transferring a fluid from a container having a body with an open first end and a piston within the body, the transfer device comprising an outer housing which is designed to receive a cartridge assembly which includes the container, the plunger rod aligned with the piston in the body, a spring position to drive the plunger rod in a direction towards the piston, a retractor to move the plunger rod from an activated position wherein the spring is extended to a non-activated position wherein the spring is compressed, and an actuator to permit the spring to be released to drive the plunger rod to move the piston within the container body. Typically, the device is used for transferring fluid from one container to a further container.
摘要翻译： 用于将流体从具有敞开的第一端和活塞的容器的容器传送到所述主体内的传送装置，所述传送装置包括外壳，所述外壳被设计成容纳包括所述容器的盒组件，所述柱塞杆与 活塞在主体中，弹簧位置以沿朝向活塞的方向驱动柱塞杆，牵开器将柱塞杆从活动位置移动，其中弹簧延伸到非活动位置，其中弹簧被压缩，以及 致动器以允许弹簧被释放以驱动柱塞杆以使活塞在容器主体内移动。 通常，该装置用于将流体从一个容器传送到另一容器。
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公开(公告)号：US20090082751A1
公开(公告)日：2009-03-26
申请号：US12157867
申请日：2008-06-13
IPC分类号： A61J1/20
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051
摘要： A system and method for transferring a fluid from a first container to a second container, the system comprising a first container (112) having a fluid (126) therein, the first container being sealed by a septum (124) and a piston (122), the second container being sealed at its mouth by a pierceable septum (132) and having a plunger (130) at the opposite end, a moveable needle shuttle (116) having first (144) and second (146) piercing ends, the arrangement being such that upon advancement of the first container with respect to the second container, a second one of the piercing ends (144) is adapted to pierce plunger (130) of the second container and a first piercing end (146) being designed to pierce the septum (124) of the first container.
摘要翻译： 一种用于将流体从第一容器传送到第二容器的系统和方法，所述系统包括其中具有流体（126）的第一容器（112），所述第一容器由隔膜（124）和活塞（122）密封 ），第二容器在其口部由可刺破的隔膜（132）密封并且在相对端具有柱塞（130），具有第一（144）和第二（146）穿刺端部的可移动的针梭（116） 布置使得在相对于第二容器推进第一容器时，穿刺端（144）中的第二个适于刺穿第二容器的柱塞（130），并且第一刺穿端（146）设计成 刺穿第一个容器的隔膜（124）。
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公开(公告)号：US20130018324A1
公开(公告)日：2013-01-17
申请号：US13261424
申请日：2011-02-28
IPC分类号： A61M5/32
CPC分类号： A61M5/3202 , A61M5/2466 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289
摘要： An injection device (10) comprising a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub being moveable from a first position wherein the distal end piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of the housing (12), a spring (23) biasing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing (12), and a plunger rod assembly (66) for exerting pressure on the cartridge receiving member (48) to move the cartridge (26) and the needle hub (38) from the first position to the second position, the plunger rod assembly (66) and the cartridge receiving member (48) being arranged such that when the cartridge rod assembly is pushed, a rotational movement is imparted to the cartridge receiving member (48) to thereby prevent access to the cartridge after injection.
摘要翻译： 一种注射装置（10），包括壳体（12），可在所述壳体（12）内滑动的针座（38），具有远端刺穿尖端（42）和近端刺穿尖端（44）的针（40） 所述针毂可从第一位置移动，其中所述远端刺穿末端（42）处于所述壳体内至第二位置，其中所述远端刺穿末端（42）从所述壳体（12）向外延伸，弹簧（23） 将针座（38）偏置到第一位置，以及安装在壳体（12）内的盒容纳构件（48），以及用于在盒容纳构件（48）上施加压力以移动 盒（26）和针座（38）从第一位置到第二位置，柱塞杆组件（66）和盒接收构件（48）被布置成使得当推动盒式杆组件时，旋转运动 被施加到盒接收构件（48），从而防止盒后部进入 呃注射。
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公开(公告)号：US08088118B2
公开(公告)日：2012-01-03
申请号：US12157867
申请日：2008-06-13
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051
摘要： A system and method for transferring a fluid from a first container to a second container, the system comprising a first container (112) having a fluid (126) therein, the first container being sealed by a septum (124) and a piston (122), the second container being sealed at its mouth by a pierceable septum (132) and having a plunger (130) at the opposite end, a moveable needle shuttle (116) having first (144) and second (146) piercing ends, the arrangement being such that upon advancement of the first container with respect to the second container, a second one of the piercing ends (144) is adapted to pierce plunger (130) of the second container and a first piercing end (146) being designed to pierce the septum (124) of the first container.
摘要翻译： 一种用于将流体从第一容器传送到第二容器的系统和方法，所述系统包括其中具有流体（126）的第一容器（112），所述第一容器由隔膜（124）和活塞（122）密封 ），第二容器在其口部由可刺破的隔膜（132）密封并且在相对端具有柱塞（130），具有第一（144）和第二（146）穿刺端部的可移动的针梭（116） 布置使得在相对于第二容器推进第一容器时，穿刺端（144）中的第二个适于刺穿第二容器的柱塞（130），并且第一刺穿端（146）设计成 刺穿第一个容器的隔膜（124）。
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公开(公告)号：US09452267B2
公开(公告)日：2016-09-27
申请号：US13261424
申请日：2011-02-28
CPC分类号： A61M5/3202 , A61M5/2466 , A61M5/326 , A61M5/3272 , A61M5/3287 , A61M5/3293 , A61M2005/2414 , A61M2005/247 , A61M2005/3267 , A61M2005/3289
摘要： An injection device (10) comprising a housing (12), a needle hub (38) slidable within the housing (12), a needle (40) having a distal end piercing tip (42) and a proximal end piercing tip (44), the needle hub being moveable from a first position wherein the distal end piercing tip (42) is within the housing to a second position wherein the distal end piercing tip (42) extends outwardly of the housing (12), a spring (23) biasing the needle hub (38) towards the first position, and a cartridge receiving member (48) mounted within the housing (12), and a plunger rod assembly (66) for exerting pressure on the cartridge receiving member (48) to move the cartridge (26) and the needle hub (38) from the first position to the second position, the plunger rod assembly (66) and the cartridge receiving member (48) being arranged such that when the cartridge rod assembly is pushed, a rotational movement is imparted to the cartridge receiving member (48) to thereby prevent access to the cartridge after injection.
摘要翻译： 一种注射装置（10），包括壳体（12），可在所述壳体（12）内滑动的针座（38），具有远端刺穿尖端（42）和近端刺穿尖端（44）的针（40） 所述针毂可从第一位置移动，其中所述远端刺穿末端（42）处于所述壳体内至第二位置，其中所述远端刺穿末端（42）从所述壳体（12）向外延伸，弹簧（23） 将针座（38）偏置到第一位置，以及安装在壳体（12）内的盒容纳构件（48），以及用于在盒容纳构件（48）上施加压力以移动 盒（26）和针座（38）从第一位置到第二位置，柱塞杆组件（66）和盒接收构件（48）被布置成使得当推动盒式杆组件时，旋转运动 被施加到盒接收构件（48），从而防止盒后部进入 呃注射。
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8.发明授权Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge 有权用于将容纳第一物质的小瓶的内容物与存储在筒中的第二物质混合的重构系统公开(公告)号：US08100154B2
公开(公告)日：2012-01-24
申请号：US11974737
申请日：2007-10-16
IPC分类号： B65B1/04
CPC分类号： A61J1/2089 , A61J1/062 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2055 , A61J1/2065
摘要： A transfer assembly for transfering a fluid to a vial, admixing the same and then returning the fluid to a cartridge, the transfer assembly having a vial gripper located at a first end and a cartridge holder at the second end of an elongated outer housing, a fluid passageway extending between the vial gripper and the cartridge holder with piercing elements being located at respective ends of the fluid passageway. In a preferred embodiment, an adaptor is mounted on the end of the outer housing where the cartridge holder is situated. The adaptor may move from a retracted to an extended position wherein it will surround the needle.
摘要翻译： 一种转移组件，用于将流体转移到小瓶中，将其混合，然后将流体返回到药筒，转移组件具有位于第一端的小瓶夹持器和位于细长外壳体的第二端处的药筒保持器， 流体通道在小瓶夹持器和药筒保持器之间延伸，穿刺元件位于流体通道的相应端部处。 在优选实施例中，适配器安装在外壳的其中盒保持器所在的端部。 适配器可以从缩回移动到延伸位置，其中它将围绕针。
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9.发明申请Device and Method for Topical Application of Therapeutics or Cosmetic Compositions 审中-公开局部应用治疗或化妆品组合物的装置和方法公开(公告)号：US20110106021A1
公开(公告)日：2011-05-05
申请号：US12911398
申请日：2010-10-25
申请人： Curtis Ruegg , David Reynolds , Daniel MacDonald , Yan Tremblay
发明人： Curtis Ruegg , David Reynolds , Daniel MacDonald , Yan Tremblay
IPC分类号： A61M35/00
CPC分类号： A45D34/04 , A45D2200/058 , A61J1/201 , A61J1/2013 , A61J1/2065 , A61J1/2089 , A61J1/2096 , A61K8/64 , A61K8/90 , A61K8/99 , A61Q19/00 , A61Q19/08
摘要： This invention relates to devices and methods for safely reconstituting and administering topical therapeutic or cosmetic compositions. The topical applicator according to the invention is particularly well suited for storing, reconstituting, and administering or applying highly toxic substances.
摘要翻译： 本发明涉及用于安全地重建和施用局部治疗或化妆品组合物的装置和方法。 根据本发明的局部给药器特别适用于储存，重建和施用或施用高毒性物质。
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10.发明申请Device and Method for Topical Application of Therapeutics or Cosmetic Compositions 审中-公开局部应用治疗或化妆品组合物的装置和方法公开(公告)号：US20120238969A1
公开(公告)日：2012-09-20
申请号：US13395830
申请日：2010-10-25
申请人： Curtis L Ruegg , David Reynolds , Daniel MacDonald , Yan Tremblay
发明人： Curtis L Ruegg , David Reynolds , Daniel MacDonald , Yan Tremblay
IPC分类号： A61M35/00
CPC分类号： A45D34/04 , A45D2200/058 , A61J1/201 , A61J1/2013 , A61J1/2065 , A61J1/2089 , A61J1/2096 , A61K8/64 , A61K8/90 , A61K8/99 , A61Q19/00 , A61Q19/08
摘要： This invention relates to devices and methods for safely reconstituting and administering topical therapeutic or cosmetic compositions. The topical applicator according to the invention is particularly well suited for storing, reconstituting, and administering or applying highly toxic substances.
摘要翻译： 本发明涉及用于安全地重建和施用局部治疗或化妆品组合物的装置和方法。 根据本发明的局部给药器特别适用于储存，重建和施用或施用高毒性物质。
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