公开(公告)号：US20240122709A1

公开(公告)日：2024-04-18

申请号：US18395235

申请日：2023-12-22

申请人： EDWARDS LIFESCIENCES CORPORATION

发明人： Lauren R. Freschauf ,  Eric Michael Oberwise ,  Grant Matthew Stearns ,  Chris J. Okos ,  Eran Hoffer ,  Rupesh Gajanan Nawalakhe ,  Sandip Vasant Pawar ,  Sergio Delgado ,  Munir Hicham Eltal

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61F2220/0008 ,  A61F2220/0041 ,  A61F2250/0007

摘要： An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The implantable device or implant can include a pair of paddles frame a coaptation element. The coaptation element defines a first area when viewed from above. The paddle frames define when viewed from above. A ratio of the second area to the first area is greater than or equal to 2 to 1.

公开(公告)号：US20140235984A1

公开(公告)日：2014-08-21

申请号：US14168932

申请日：2014-01-30

申请人： Edwards Lifesciences Corporation

发明人： Jennifer L. Wilbur ,  Michael Higgins ,  Paul S. Van Wieren ,  Alexander H. Siemons ,  Chris J. Okos

IPC分类号： A61B5/15 ,  A61B5/157 ,  A61B5/155

CPC分类号： A61B5/150992 ,  A61B5/14503 ,  A61B5/14532 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150229 ,  A61B5/150259 ,  A61B5/150755 ,  A61B5/155 ,  A61B5/157 ,  A61B5/6866

摘要： The present invention provides a blood parameter sensing system that may include a sensor, a blood access system, a flow controller and a monitor system. The blood access system may include a blood draw member having an internal configuration adapted to avoid clotting without the use of anticoagulants and under a range of flow profiles, including small volume blood draws. The flow controller may be configured to adapt to a range of access devices by using feedback from the sensor and monitor to customize flow profiles. The monitor system is configured to reduce parameter measurement error by modeling sensitivity change during system startup or reconnect.

摘要翻译： 本发明提供一种血液参数检测系统，其可以包括传感器，血液存取系统，流量控制器和监视器系统。 血液存取系统可以包括具有适于避免凝血而不使用抗凝剂并且在一定范围的流动特征（包括小体积血液抽吸）下的内部构造的血液抽吸构件。 流量控制器可以被配置为通过使用来自传感器和监视器的反馈来适应一系列访问设备来定制流量简档。 监视器系统配置为通过在系统启动或重新连接期间建立灵敏度更改来降低参数测量误差。

公开(公告)号：US20240050228A1

公开(公告)日：2024-02-15

申请号：US18487101

申请日：2023-10-15

申请人： EDWARDS LIFESCIENCES CORPORATION

发明人： Eric Robert Dixon ,  Lauren R. Freschauf ,  Rachel Liat David Foreman ,  Rachel Ann Cooney ,  Michael J. Popp ,  Chris J. Okos ,  Eric Michael Oberwise ,  Steven M. Ford

IPC分类号： A61F2/24

CPC分类号： A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2220/0091

摘要： Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps can have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position. The device can have an indicator that can move between not engaged by a leaflet and engaged by a leaflet conditions to indicate capture of a leaflet of the native valve. The indicator can be compressible. The indicator can be flattenable. The indicator can include one or more marker.

公开(公告)号：US20230181314A1

公开(公告)日：2023-06-15

申请号：US18168445

申请日：2023-02-13

申请人： EDWARDS LIFESCIENCES CORPORATION

发明人： Grant Matthew Stearns ,  Chris J. Okos ,  Seung-Beom Yi

IPC分类号： A61F2/24

CPC分类号： A61F2/24 ,  A61F2220/0016

摘要： An implantable device or implant includes an anchor portion comprising one or more anchors. The anchors are configured to attach to one or more leaflets of a native heart valve. The anchors are configured to move between an open position and a closed position. The device or implant includes an indication feature that is movable between an allowable tension position and an exceeded tension position. When the anchors are attached to the leaflets of the native heart valve, the indication feature indicates to a user when an amount of force applied to the anchor portion by the leaflets of the native heart valve exceeds a pre-set or predetermined amount of force.

公开(公告)号：US20210145571A1

公开(公告)日：2021-05-20

申请号：US17160307

申请日：2021-01-27

申请人： Edwards Lifesciences Corporation

发明人： Eric Robert Dixon ,  Lauren R. Freschauf ,  Rachel Liat David Foreman ,  Rachel Ann Gohres ,  Michael J. Popp ,  Chris J. Okos ,  Eric Michael Oberwise ,  Steven M. Ford

IPC分类号： A61F2/24

摘要： Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps may have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position, and an indicator arm connected to at least one of the fixed arm and the movable arm. The indicator arm can move between a first position when not engaged with a leaflet and a second, engaged position when engaged with the leaflet. Movement of the indicator arm from the first position to the second, engaged position indicates capture of a leaflet of the native valve by the pair of paddles.

公开(公告)号：US11839544B2

公开(公告)日：2023-12-12

申请号：US17160307

申请日：2021-01-27

申请人： Edwards Lifesciences Corporation

发明人： Eric Robert Dixon ,  Lauren R. Freschauf ,  Rachel Liat David Foreman ,  Rachel Ann Gohres ,  Michael J. Popp ,  Chris J. Okos ,  Eric Michael Oberwise ,  Steven M. Ford

IPC分类号： A61F2/24

CPC分类号： A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2220/0091

摘要： Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps may have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position, and an indicator arm connected to at least one of the fixed arm and the movable arm. The indicator arm can move between a first position when not engaged with a leaflet and a second, engaged position when engaged with the leaflet. Movement of the indicator arm from the first position to the second, engaged position indicates capture of a leaflet of the native valve by the pair of paddles.

公开(公告)号：US20230363911A1

公开(公告)日：2023-11-16

申请号：US18352860

申请日：2023-07-14

申请人： EDWARDS LIFESCIENCES CORPORATION

发明人： Florian Georg Deuschl ,  Chris J. Okos ,  Waina Michelle Chu ,  Jian Lin Phan ,  Lauren R. Freschauf ,  Wen Yan Chen

IPC分类号： A61F2/24

CPC分类号： A61F2/2463 ,  A61F2/2436 ,  A61F2220/0075

摘要： An implantable device is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The implantable device includes a cover. The cover can be attached to one or more sleeves, can have a portion that has a lower coefficient of friction, and/or can have separate pieces that cover different portions of the implantable device.

公开(公告)号：US20230338145A1

公开(公告)日：2023-10-26

申请号：US18339497

申请日：2023-06-22

申请人： EDWARDS LIFESCIENCES CORPORATION

发明人： Eric Michael Oberwise ,  Grant Matthew Stearns ,  Lauren R. Freschauf ,  Michael J. Popp ,  Steven M. Ford ,  Rachel Liat David Foreman ,  Rachel Ann Gohres ,  Chris J. Okos ,  Eric Robert Dixon ,  Asher L. Metchik ,  Michael D. Franklin ,  Travis Zenyo Oba ,  Daniel James Montoya ,  Mindy Lee Ann Black ,  Aviv Galon ,  Munir Hicham Eltal ,  Eran Hoffer

IPC分类号： A61F2/24

CPC分类号： A61F2/246 ,  A61F2/2466 ,  A61F2/2445 ,  A61F2/2463 ,  A61F2220/0016 ,  A61F2210/0014

摘要： An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some implementations, the implantable device or implant, or one or more portions thereof, can be configured to expand and/or contract. For example, the implantable device or implant can narrow during delivery and expand on implantation on the native heart valve.