公开(公告)号：US20250152359A1

公开(公告)日：2025-05-15

申请号：US18962021

申请日：2024-11-27

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Grant Matthew Stearns ,  Rachel Ann Cooney ,  Rachel Liat David Foreman ,  Alex Philip McCann ,  David M. Taylor

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: In a method of treating an atrioventricular valve, a sealing element is deployed in a native atrioventricular valve of a heart at a position between native atrioventricular valve leaflets to contact the native atrioventricular valve leaflets. The sealing element is controlled by user input to both radially expand and radially reduce the sealing element while at the position between the native atrioventricular valve leaflets. At least one of the native atrioventricular leaflets is secured between an inner anchor member and an outer anchor member to support the sealing element at a desired position between the native atrioventricular valve leaflets.

公开(公告)号：US20240050228A1

公开(公告)日：2024-02-15

申请号：US18487101

申请日：2023-10-15

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Eric Robert Dixon ,  Lauren R. Freschauf ,  Rachel Liat David Foreman ,  Rachel Ann Cooney ,  Michael J. Popp ,  Chris J. Okos ,  Eric Michael Oberwise ,  Steven M. Ford

IPC: A61F2/24

CPC classification number: A61F2/246 ,  A61F2/2463 ,  A61F2/2466 ,  A61F2220/0008 ,  A61F2220/0091

Abstract: Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps can have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position. The device can have an indicator that can move between not engaged by a leaflet and engaged by a leaflet conditions to indicate capture of a leaflet of the native valve. The indicator can be compressible. The indicator can be flattenable. The indicator can include one or more marker.

公开(公告)号：US12201734B2

公开(公告)日：2025-01-21

申请号：US17054505

申请日：2018-10-08

Applicant: Edwards Lifesciences Corporation

Inventor： Steven M. Claessens ,  Rachel Ann Cooney

IPC: A61L2/00 ,  A61F2/02 ,  A61L2/18 ,  A61L27/36 ,  C08J3/28

Abstract: A method of preparing a sterilized heart valve, the method comprising: compressing a compressible frame of a heart valve from an expanded configuration to a crimped configuration; the heart valve comprising the frame and a plurality of leaflets coupled to the frame; wherein each of the plurality of leaflets comprises a dry, unfixed, decellularized, antigen-free biological tissue that has been treated with a solution comprising a polyol or polyhydric alcohol; packaging the heart valve within a sealed packaging system while the heart valve is in the crimped configuration; and sterilizing the heart valve packaged within the sealed packaging system with one or more cycles of electron beam radiation.

公开(公告)号：US12186191B2

公开(公告)日：2025-01-07

申请号：US17514757

申请日：2021-10-29

Applicant: Edwards Lifesciences Corporation

Inventor： Sergio Delgado ,  Lauren R. Freschauf ,  Eric Robert Dixon ,  Grant Matthew Stearns ,  Rachel Ann Cooney ,  Rachel Liat David Foreman ,  Alex Philip McCann ,  David M. Taylor

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34 ,  A61L27/04

Abstract: An device for treating a native valve includes a sealing element and an anchoring element. The sealing element is made from a braided mesh material. The sealing element is dimensioned to be deployed in an annulus of a native valve of a heart at a position between native valve leaflets to contact the native valve leaflets during ventricular systole to create a seal to prevent regurgitation of blood from the left ventricle to the left atrium. The sealing element is configured to both be radially expanded and radially reduced while at the position between the native valve leaflets. The anchoring element is adapted for deployment in the heart, the anchoring element coupled to the sealing element and configured to support the sealing element at the desired position between native valve leaflets.

公开(公告)号：US11766330B2

公开(公告)日：2023-09-26

申请号：US16847577

申请日：2020-04-13

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Alex Philip McCann ,  Grant Matthew Stearns ,  Eric Robert Dixon ,  Yoon Hee Kwon ,  Michael J. Popp ,  Sergio Delgado ,  Lauren R. Freschauf ,  Rachel Ann Cooney ,  Rachel Liat David Foreman

IPC: A61F2/24 ,  A61B17/00 ,  A61B17/04 ,  A61B17/34

CPC classification number: A61F2/246 ,  A61B17/00234 ,  A61B17/0469 ,  A61B17/3468 ,  A61F2/2448 ,  A61F2/2463 ,  A61F2/2466 ,  A61B17/0401 ,  A61B2017/00243 ,  A61B2017/00526 ,  A61B2017/00557 ,  A61B2017/00783 ,  A61B2017/00867 ,  A61B2017/0464 ,  A61F2/2445 ,  A61F2210/0014 ,  A61F2220/0016 ,  A61F2220/0041 ,  A61F2220/0091 ,  A61F2230/0093 ,  A61F2240/001 ,  A61F2250/0003

Abstract: An implantable prosthetic device has a coaption element and at least one anchor. The coaption element is configured to be positioned within the native heart valve orifice to help fill a space where the native valve is regurgitant and form a more effective seal. The coaption element can have a structure that is impervious to blood. The coaption element can be connected to leaflets of the native valve by the anchor.