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13 条记录 (耗时 0.014 秒)

    Absorbable Polymeric Blend Compositions with Precisely Controllable Absorption Rates, Processing Methods, and Dimensionally Stable Medical Devices Therefrom
    5.
    发明申请
    Absorbable Polymeric Blend Compositions with Precisely Controllable Absorption Rates, Processing Methods, and Dimensionally Stable Medical Devices Therefrom 审中-公开
    可吸收的具有精确控制吸收率的聚合物混合组合物，加工方法和尺寸稳定的医疗器械

    公开(公告)号：US20150148496A1

    公开(公告)日：2015-05-28

    申请号：US14548536

    申请日：2014-11-20

    申请人： Ethicon, Inc.

    发明人： Dennis D. Jamiolkowski ,  Daniel Steiger ,  Brian M. Kelly ,  Christopher DeFelice ,  Sasa Andjelic ,  Modesto Erneta

    IPC分类号： A61L31/04 ,  A61L31/14

    CPC分类号： A61L31/041 ,  A61B17/06166 ,  A61B17/064 ,  A61B2017/00004 ,  A61L17/105 ,  A61L27/26 ,  A61L27/58 ,  A61L31/148 ,  C08L67/04 ,  C08L2205/03 ,  C08L2666/18

    摘要： Novel absorbable polymeric blends are disclosed. The blends have a first absorbable polymer type that is a polylactide polymer or a copolymer of lactide and glycolide and a second absorbable polymer type that is poly(p-dioxanone), wherein the first absorbable polymer type or the second absorbable polymer type or the first absorbable polymer type and the second absorbable polymer type additionally comprise a first polymeric component and a second polymeric component. The first polymeric component has a higher weight average molecular weight than the second polymeric component and at least one of said components is at least partially end-capped by a carboxylic acid. The novel polymeric blends are useful for manufacturing medical devices having dimensional stability, having engineered degradation and breaking strength retention in vivo. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.

    摘要翻译： 公开了新颖的可吸收聚合物共混物。 共混物具有第一可吸收聚合物类型，其是聚丙交酯聚合物或丙交酯和乙交酯的共聚物，以及聚（对二恶烷酮）的第二可吸收聚合物类型，其中第一可吸收聚合物类型或第二可吸收聚合物类型或第一可吸收聚合物类型 可吸收聚合物类型和第二可吸收聚合物类型另外包含第一聚合物组分和第二聚合物组分。 第一聚合物组分具有比第二聚合物组分更高的重均分子量，并且至少一种所述组分至少部分地被羧酸封端。 新型聚合物共混物可用于制造具有尺寸稳定性，具有工程化降解和体内断裂强度保持性的医疗装置。 还公开了由这些新型聚合物共混物制成的新型可吸收医疗器件以及新颖的制造方法。

    Mechanically Strong Absorbable Polymeric Blend Compositions of Precisely Controllable Absorption Rates, Processing Methods, And Products Therefrom
    7.
    发明申请
    Mechanically Strong Absorbable Polymeric Blend Compositions of Precisely Controllable Absorption Rates, Processing Methods, And Products Therefrom 审中-公开
    机械强吸收聚合物混合组合物的精确控制吸收率，加工方法和产品

    公开(公告)号：US20130315963A1

    公开(公告)日：2013-11-28

    申请号：US13833690

    申请日：2013-03-15

    申请人： ETHICON, INC.

    发明人： Modesto Erneta ,  Daniel Steiger ,  Dennis D. Jamiolkowski

    IPC分类号： A61L17/12 ,  A61B17/06 ,  A61L17/00

    摘要： Novel absorbable polymer blends are disclosed. The blends are useful for manufacturing medical devices having engineered degradation and breaking strength retention in vivo. The blends consist of a first absorbable polymeric component and a second absorbable polymeric component. The weight average molecular weight of the first polymeric component is higher than the weight average molecular weight of the second polymeric component. At least at least one of said components is at least partially end-capped by a carboxylic acid group. Further aspects are medical devices made therefrom.

    摘要翻译： 公开了新颖的可吸收聚合物共混物。 该混合物可用于制造具有工程化降解和体内断裂强度保留的医疗装置。 共混物由第一可吸收聚合物组分和第二可吸收聚合物组分组成。 第一聚合物组分的重均分子量高于第二聚合物组分的重均分子量。 所述组分中的至少一种至少部分被羧酸基部分封端。 其他方面是由其制成的医疗装置。