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32 条记录 (耗时 0.022 秒)

    Shoe midsole and footwear
    7.
    发明授权
    Shoe midsole and footwear 有权
    鞋中底和鞋类

    公开(公告)号：US08973287B2

    公开(公告)日：2015-03-10

    申请号：US12737806

    申请日：2009-06-11

    申请人： Osamu Shibata ,  Masao Shibata

    发明人： Osamu Shibata ,  Masao Shibata

    IPC分类号： A43B13/38 ,  A43B5/00 ,  A43B13/18 ,  A43B13/00 ,  A43B7/14 ,  A43B13/20

    CPC分类号： A43B13/189 ,  A43B7/144 ,  A43B7/1445 ,  A43B7/146 ,  A43B13/20

    摘要： A shoe midsole has a sole plate, a plurality of blades integrally standing on the sole plate, a cover bonded to the circumference of the sole plate, and a fluid sealed between the sole plate and the cover. A first concave part in a shape equivalent to a sole of a foot is formed on the surface of the sole plate, on which the plurality of blades stand, wherein the plurality of blades are accommodated within the first concave part. The plurality of blades are aligned at a predetermined interval in a direction nearly orthogonal to the longitudinal direction of the sole plate, and some of the plurality of blades are tilted toward the toe.

    摘要翻译： 鞋底具有底板，整体地站立在底板上的多个叶片，与底板的圆周接合的盖子以及密封在底板和盖板之间的流体。 在多个叶片所在的底板的表面上形成有与脚底相当形状的第一凹部，其中多个叶片容纳在第一凹部内。 多个叶片在与底板的纵向近似正交的方向上以预定间隔排列，并且多个叶片中的一些叶片朝向趾部倾斜。

    Method of controlling wavelength-tunable laser
    8.
    发明授权
    Method of controlling wavelength-tunable laser 有权
    控制波长可调激光器的方法

    公开(公告)号：US08311068B2

    公开(公告)日：2012-11-13

    申请号：US13029539

    申请日：2011-02-17

    申请人： Masao Shibata ,  Hirokazu Tanaka ,  Tsutomu Ishikawa

    发明人： Masao Shibata ,  Hirokazu Tanaka ,  Tsutomu Ishikawa

    IPC分类号： H01S3/10

    CPC分类号： H01S5/06256 ,  H01S5/02415 ,  H01S5/0612 ,  H01S5/0617 ,  H01S5/06258 ,  H01S5/06837 ,  H01S5/0687 ,  H01S5/1209 ,  H01S5/1212

    摘要： A method of controlling a wavelength-tunable laser selecting an oscillation wavelength with a combination of a plurality of wavelength selection portions of which wavelength peak is different from each other, comprising: a first step of confirming a control direction of the wavelength selection portion in a case where a setting value is changed from a first setting value for achieving the first wavelength to a second setting value for achieving the second wavelength; a second step of setting a setting value that is shifted from the second setting value in a direction that is opposite of a pre-determined changing direction on the wavelength selection portion as a prepared setting value, when the control direction confirmed in the first step is opposite to the pre-determined changing direction; and a third step of changing the prepared setting value set in the second step to the second setting value.

    摘要翻译： 一种波长可变激光器的选择振荡波长的方法，其中波长峰值彼此不同的多个波长选择部分的组合，包括：确定波长选择部分的控制方向的第一步骤 将设定值从实现第一波长的第一设定值改变为实现第二波长的第二设定值的情况; 第二步骤，当在第一步骤中确认的控制方向为第一步骤时，在与波长选择部分上的预定改变方向相反的方向上设置从第二设定值偏移的设定值作为准备好的设定值， 与预先确定的改变方向相反; 以及将在第二步骤中设置的准备好的设定值改变为第二设定值的第三步骤。

    Method for the preparation of N-glycolyl neuraminic acid from Cucumaria echinata
    9.
    发明授权
    Method for the preparation of N-glycolyl neuraminic acid from Cucumaria echinata 失效
    从黄瓜科制备N-羟乙酰神经氨酸的方法

    公开(公告)号：US6143533A

    公开(公告)日：2000-11-07

    申请号：US525323

    申请日：2000-03-13

    申请人： Toshihisa Sumi ,  Hideki Ohba ,  Toru Ikegami ,  Masao Shibata ,  Tsuyoshi Sakaki ,  Imre Sallay ,  Sung Soo Park

    发明人： Toshihisa Sumi ,  Hideki Ohba ,  Toru Ikegami ,  Masao Shibata ,  Tsuyoshi Sakaki ,  Imre Sallay ,  Sung Soo Park

    IPC分类号： C07H7/027 ,  A61K35/56 ,  C07H1/08 ,  C12P7/58 ,  C12P7/40 ,  A61K35/12

    CPC分类号： C12P7/58

    摘要： Disclosed is an efficient and economical method for the preparation of N-glycolyl neuraminic acid in a high purity from an inexpensive abundant source material. The method comprises dispersing body tissues of an echinodermatous marine animal Cucumaria echinata in an aqueous medium, preferably, using a dry powder of the tissues prepared in advance, in which the tissues are proteolytically decomposed to isolate N-glycolyl neuraminic acid in the form of an aqueous solution containing polypeptides as a by-product, followed by separation of N-glycolyl neuraminic acid from the aqueous solution by removing the polypeptides and purification of the compound in a process utilizing an ion-exchange treatments.

    摘要翻译： 公开了一种从廉价丰富的原料制备高纯度的N-羟乙酰神经氨酸的有效和经济的方法。 该方法包括将棘皮动物海洋动物黄瓜（Cucumaria echinata）的身体组织分散在水性介质中，优选使用预先制备的组织的干粉末，其中组织被蛋白水解分解以分离出N-羟乙酰神经氨酸 水溶液，其含有作为副产物的多肽，随后通过在使用离子交换处理的方法中除去多肽和化合物的纯化从水溶液中分离N-羟乙酰神经氨酸。

    Antibody recognizing GM1 ganglioside-bound amyloid β-protein and DNA encoding the antibody
    10.
    发明授权
    Antibody recognizing GM1 ganglioside-bound amyloid β-protein and DNA encoding the antibody 有权
    识别GM1神经节苷脂结合淀粉样β蛋白的抗体和编码抗体的DNA

    公开(公告)号：US07339035B2

    公开(公告)日：2008-03-04

    申请号：US10768193

    申请日：2004-02-02

    申请人： Katsuhiko Yanagisawa ,  Masao Shibata

    发明人： Katsuhiko Yanagisawa ,  Masao Shibata

    IPC分类号： C07K16/28 ,  C07K16/00

    CPC分类号： C07K16/18 ,  A61K2039/505 ,  C07K2317/565

    摘要： It is intended to provide an antibody efficacious in diagnosing, preventing or treating Alzheimer's disease, DNA encoding the antibody, a method of screening a drug and drugs. The amino acid sequence and the gene sequence of the variable region of an antibody, which specifically recognizes a GM1 ganglioside-bound amyloid β-protein occurring in the early stage of β-amyloid fibril formation, are determined. Based on the data of the amino acid sequence and the gene sequence thus obtained, an antibody is designed.

    摘要翻译： 旨在提供一种有效诊断，预防或治疗阿尔茨海默氏病的抗体，编码抗体的DNA，筛选药物和药物的方法。 确定了在β-淀粉样蛋白原纤维形成的早期阶段中发生的GM1神经节苷脂结合的淀粉样β蛋白的抗体可变区的氨基酸序列和基因序列。 根据所得氨基酸序列和基因序列的数据，设计抗体。