Method for reducing calcification of biological tissue used implantable
bioprostheses
    2.
    发明授权
    Method for reducing calcification of biological tissue used implantable bioprostheses 失效
    使用可植入生物假体减少生物组织钙化的方法

    公开(公告)号:US5882850A

    公开(公告)日:1999-03-16

    申请号:US949617

    申请日:1997-10-14

    摘要: Biological materials are treated with an organic chemical agent, dimethyl sulfoxide, to delay the onset of in vivo calcification. The biological materials so treated become resistant to calcification over a prolonged period with no known deleterious effects to the host. The procedure involves the incubation of the natural biological materials in the chemical agent, prior to or after glutaraldehyde fixation, at room temperature or at temperatures up to 60.degree. C. Materials that can be treated with this process include biological materials intended for bioprostheses use, such as porcine aortic valves, porcine aortic valve leaflets, bovine, equine and porcine pericardium, aortic homografts, reconstituted collagen, and the like suitable for invasive, or in-dwelling use in a human or animal body.

    摘要翻译: 生物材料用有机化学试剂二甲基亚砜处理,以延缓体内钙化的发生。 如此处理的生物材料在长时间内变得耐钙化,对宿主没有已知的有害影响。 该方法包括将天然生物材料在化学试剂中,在戊二醛固定之前或之后,在室温或高达60℃的温度下孵育。可用该方法处理的材料包括用于生物预处理的生物材料, 例如猪主动脉瓣,猪主动脉瓣小叶,牛,马和猪心包膜,主动脉同种移植物,重建胶原蛋白等,适合在人体或动物身上进行侵入或住宅使用。

    Method of preparing water swellable gel from chitin
    4.
    发明授权
    Method of preparing water swellable gel from chitin 失效
    从几丁质制备水溶胀凝胶的方法

    公开(公告)号:US6025479A

    公开(公告)日:2000-02-15

    申请号:US899164

    申请日:1997-07-23

    IPC分类号: C08B37/08 C08L5/08 C08B15/00

    CPC分类号: C08B37/003 C08L5/08

    摘要: This invention relates to a method of preparing a form of chitin that has consistent shape in the dry form, is treated chemically such that it will swell when exposed to water to form a gel. The gel can be dried to give the dry form. The gel formation upon absorption/swelling in the presence of water and drying to give the dried form is reversible. The extent of swelling can be varied by suitably varying the chemical treatment.

    摘要翻译: 本发明涉及一种制备具有干燥形式一致形状的壳多糖形式的方法,化学处理使其在暴露于水中时会溶胀以形成凝胶。 可以将凝胶干燥以得到干燥形式。 在水的存在下吸收/溶胀时的凝胶形成并干燥得到干燥形式是可逆的。 膨胀的程度可以通过适当地改变化学处理来改变。