公开(公告)号：US11466302B2

公开(公告)日：2022-10-11

申请号：US16801200

申请日：2020-02-26

Applicant: EVOLVA SA

Inventor： Helene Lunde Robertsen ,  Iben Nordmark Andersen ,  Adam Matthew Takos ,  Swee Chuang Lim Hallwyl ,  Francesca Ambri ,  Manuel Quiros Asensio ,  Michael Dalgaard Mikkelsen ,  Jens Houghton-Larsen ,  Veronique Douchin ,  Jane Dannow Dyekjaer ,  Simon Carlsen ,  Nina Nicoline Rasmussen ,  Esben Halkjaer Hansen

IPC: C12P19/56 ,  A23L27/30 ,  C12N9/02 ,  C12N15/52 ,  C07H15/256 ,  C12N9/10 ,  C12N9/88 ,  C12N9/90

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US09957540B2

公开(公告)日：2018-05-01

申请号：US14761629

申请日：2014-02-06

Applicant: Evolva SA

Inventor： Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Ernesto Simon ,  Federico Brianza ,  Angelika Semmler ,  Kim Olsson ,  Simon Carlsen ,  Louis Düring ,  Alexei Ouspenski ,  Paula Hicks

IPC: C12P19/56 ,  A23L2/60 ,  C12N9/02 ,  C12N9/10 ,  C12N9/90 ,  C12N15/81 ,  A23L27/30

CPC classification number: C12P19/56 ,  A23L2/60 ,  A23L27/36 ,  A23V2002/00 ,  C12N9/0071 ,  C12N9/1051 ,  C12N9/1081 ,  C12N9/1085 ,  C12N9/90 ,  C12N15/81 ,  C12Y204/01 ,  C12Y204/99

Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided herein.

公开(公告)号：US20170369922A1

公开(公告)日：2017-12-28

申请号：US15541686

申请日：2016-01-29

Applicant: EVOLVA SA

Inventor： Kim Olsson ,  Ernesto Simon ,  Michael Dalgaard Mikkelsen ,  Simon Carlsen ,  Veronique Douchin ,  Swee Chuang Lim ,  Louis During

IPC: C12P19/56 ,  C12N9/10 ,  C07H15/256

CPC classification number: C12P19/56 ,  C07H15/256 ,  C12N9/1051 ,  C12P15/00 ,  C12Y204/01

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.

公开(公告)号：US20170218418A1

公开(公告)日：2017-08-03

申请号：US15328365

申请日：2015-08-07

Applicant: Evolva SA

Inventor： Veronique Douchin ,  Michael Dalgaard Mikkelsen ,  Iben Møller-Hansen

IPC: C12P19/44 ,  C12N1/16

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20160186225A1

公开(公告)日：2016-06-30

申请号：US14761629

申请日：2014-02-06

Applicant: EVOLVA SA

Inventor： Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Ernesto Simon ,  Frederico Brianza ,  Angelika Semmler ,  Kim Olsson ,  Simon Carlsen ,  Louis Düring ,  Alexei Ouspenski ,  Paula Hicks

IPC: C12P19/56 ,  A23L2/60 ,  C12N9/10

CPC classification number: C12P19/56 ,  A23L2/60 ,  A23L27/36 ,  A23V2002/00 ,  C12N9/0071 ,  C12N9/1051 ,  C12N9/1081 ,  C12N9/1085 ,  C12N9/90 ,  C12N15/81 ,  C12Y204/01 ,  C12Y204/99

Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.

Abstract translation: 本发明提供了重组生产甜菊糖苷和含有甜菊糖苷的组合物的方法。

公开(公告)号：US11041183B2

公开(公告)日：2021-06-22

申请号：US16434202

申请日：2019-06-07

Applicant: EVOLVA SA

Inventor： Kim Olsson ,  Ernesto Simon ,  Michael Dalgaard Mikkelsen ,  Simon Carlsen ,  Veronique Douchin ,  Swee Chuang Lim ,  Louis During

IPC: C12P19/56 ,  C12N9/10 ,  C12P15/00 ,  C07H15/256

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides, glycosylated ent-kaurenol, and glycosylated ent-kaurenoic acid.

公开(公告)号：US11021727B2

公开(公告)日：2021-06-01

申请号：US16002245

申请日：2018-06-07

Applicant: EVOLVA SA

Inventor： Ernesto Simon ,  Iben Nordmark Anderson ,  Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Veronique Douchin

IPC: C12P19/56 ,  C12N9/02 ,  C12N9/88 ,  C12N9/90 ,  C07K14/395 ,  C12N9/10 ,  C12P15/00

Abstract: Recombinant microorganisms are disclosed that produce steviol glycosides and have altered expression of one or more endogenous transporter or transcription factor genes, or that overexpress one or more heterologous transporters, leading to increased excretions of steviol glucosides of interest.

公开(公告)号：US10421983B2

公开(公告)日：2019-09-24

申请号：US15328365

申请日：2015-08-07

Applicant: Evolva SA

Inventor： Veronique Douchin ,  Michael Dalgaard Mikkelsen ,  Iben Møller-Hansen

IPC: C12P21/06 ,  C12P19/44 ,  C07H1/08 ,  A23L27/30 ,  C12N1/16

Abstract: The invention relates to recombinant microorganisms and methods for producing steviol glycosides and steviol glycoside precursors.

公开(公告)号：US20230279459A1

公开(公告)日：2023-09-07

申请号：US18052477

申请日：2022-11-03

Applicant: EVOLVA SA

Inventor： Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Ernesto Simon ,  Federico Brianza ,  Angelika Semmler ,  Kim Olsson ,  Simon Carlsen ,  Louis Düring ,  Alexei Ouspenski ,  Paula Hicks

IPC: C12P19/56 ,  C12N9/02 ,  C12N9/90 ,  A23L2/60 ,  C12N9/10 ,  C12N15/81 ,  A23L27/30

CPC classification number: C12P19/56 ,  C12N9/0071 ,  C12N9/90 ,  A23L2/60 ,  C12Y204/01 ,  C12N9/1051 ,  C12N9/1081 ,  C12N9/1085 ,  C12N15/81 ,  A23L27/36 ,  C12Y204/99 ,  A23V2002/00

Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.

公开(公告)号：US11530431B2

公开(公告)日：2022-12-20

申请号：US16799541

申请日：2020-02-24

Applicant: EVOLVA SA

Inventor： Michael Dalgaard Mikkelsen ,  Jorgen Hansen ,  Ernesto Simon ,  Federico Brianza ,  Angelika Semmler ,  Kim Olsson ,  Simon Carlsen ,  Louis Düring ,  Alexei Ouspenski ,  Paula Hicks

IPC: C12P19/56 ,  A23L27/30 ,  A23L2/60 ,  C12N9/02 ,  C12N9/10 ,  C12N9/90 ,  C12N15/81

Abstract: Methods for recombinant production of steviol glycoside and compositions containing steviol glycosides are provided by this invention.