公开(公告)号：US20140221794A1

公开(公告)日：2014-08-07

申请号：US14251043

申请日：2014-04-11

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/00 ,  A61B1/06

CPC classification number: A61B1/00009 ,  A61B1/0051 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/0661 ,  A61B1/0684 ,  A61B5/0084 ,  F04C2270/041

Abstract: The visibility of irregularities on the body tissue, such as a superficial microstructure or hypertrophy, is improved. Excitation light EL is emitted to a phosphor to excite and emit white light W. High absorption wavelength cut light is generated by removing components in high absorption wavelength bands A1 and A2, in which the absorption coefficient of hemoglobin in the blood is high, from the white light using a high absorption wavelength rejection filter. The subject is illuminated with the high absorption wavelength cut light, and image light of the reflected light is captured by a color CCD. A microstructure image is generated based on a signal Bp output from the B pixel of the CCD. In this microstructure image, the display of superficial microvessels is suppressed. Accordingly, the visibility of superficial microstructures, such as a pit pattern, is relatively improved.

Abstract translation: 改善身体组织上的不规则性（例如表面微结构或肥大）的可视性。 激发光EL被发射到荧光体以激发并发出白光W.通过从高吸收波长带A1和A2中除去血液中血红蛋白的吸收系数高的成分，从而产生高吸收波长切割光 白光采用高吸收波长抑制滤光片。 用高吸收波长切割光照射被摄体，并且通过彩色CCD捕获反射光的图像光。 基于从CCD的B像素输出的信号Bp生成微结构图像。 在该微结构图像中，抑制了表面微血管的显示。 因此，诸如凹坑图案的表面微结构的可视性相对提高。

公开(公告)号：US20130211217A1

公开(公告)日：2013-08-15

申请号：US13746880

申请日：2013-01-22

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Takaaki SAITO ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B5/1455 ,  A61B5/145 ,  A61B1/04 ,  A61B1/00 ,  A61B1/005 ,  A61B5/1459 ,  A61B5/00

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/00039 ,  A61B1/00045 ,  A61B1/0005 ,  A61B1/0052 ,  A61B1/04 ,  A61B1/0646 ,  A61B1/0653 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/7278 ,  A61B5/742 ,  A61B2562/046

Abstract: First and second white light is generated by excitations of phosphors with first and second laser beams having center wavelengths of 473 nm and 445 nm, respectively. The first and second white light is applied, in respective frames, sequentially to a region of interest in a subject. A color image sensor images the region of interest in the each frame. Based on a shift amount, calculated from green signals of first and second frames, between images, an image of a blue signal of the first frame is moved to be aligned with an image of a green signal and an image of a red signal of the second frame. After the alignment, an oxygen saturation image representing an oxygen saturation level of hemoglobin in blood is produced from the blue signal of the first frame and green and red signals of the second frame, and displayed on a display.

Abstract translation: 第一和第二白光通过具有分别具有473nm和445nm的中心波长的第一和第二激光束的荧光体的激发产生。 第一和第二白光在相应的帧中顺序地施加到被摄体中的感兴趣区域。 彩色图像传感器在每个帧中成像感兴趣的区域。 基于从第一帧和第二帧的绿色信号在图像之间计算的移位量，移动第一帧的蓝色信号的图像以与绿色信号的图像和红色信号的图像对准 第二帧。 在对准之后，从第一帧的蓝色信号和第二帧的绿色和红色信号产生表示血液中血红蛋白的氧饱和度水平的氧饱和度图像，并显示在显示器上。

公开(公告)号：US20150313517A1

公开(公告)日：2015-11-05

申请号：US14697763

申请日：2015-04-28

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Yoshinori MORIMOTO ,  Takumi DEJIMA

IPC: A61B5/1459 ,  A61B5/145 ,  A61B1/06 ,  A61B1/05 ,  A61B1/313

CPC classification number: A61B5/1459 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/043 ,  A61B1/045 ,  A61B1/05 ,  A61B1/0638 ,  A61B1/0669 ,  A61B1/3132 ,  A61B5/14542 ,  A61B5/1455

Abstract: The invention provides an endoscope system for generating an oxygen saturation image that can be used for various medical applications, such as oxygen saturation monitoring during surgery. A clip 141 is attached to the surrounding tissue of a tumor CN from the luminal side. The tissue to which the clip 141 is attached becomes an ischemic part CL. An oxygen saturation image is generated from image information obtained by imaging the tissue on the abdominal cavity side. In the oxygen saturation image, the ischemic part CL is displayed as a low oxygen region. Accordingly, it becomes easy to find the location of the tumor CN even from the abdominal cavity side.

Abstract translation: 本发明提供一种用于产生可用于各种医疗应用的氧饱和度图像的内窥镜系统，例如手术期间的氧饱和度监测。 夹子141从腔侧连接到肿瘤CN的周围组织。 夹子141所附着的组织成为缺血部分CL。 从通过对腹腔侧组织成像获得的图像信息产生氧饱和度图像。 在氧饱和度图像中，缺血部分CL被显示为低氧区域。 因此，即使从腹腔侧也容易找到肿瘤CN的位置。

公开(公告)号：US20140187953A1

公开(公告)日：2014-07-03

申请号：US14141060

申请日：2013-12-26

Applicant: FUJIFILM Corporation

Inventor： Yukiya MIYACHI ,  Hiroshi YAMAGUCHI ,  Yasunori OHTA ,  Tsuyoshi TANABE ,  Noriaki IDA ,  Shin NAKATA

IPC: A61B8/00 ,  A61B8/14

CPC classification number: G01S15/8952 ,  A61B8/14 ,  A61B8/5269 ,  G01S7/52049 ,  G01S15/8995

Abstract: In an ultrasound diagnostic apparatus, when a compound image is produced, delay correction is performed on all of ultrasound images (sub frames) to be combined based on sound velocities set for respective segment regions obtained by dividing the subject. Owing to this configuration, the ultrasound diagnostic apparatus can produce a high quality compound image by spatial compounding or frequency compounding without being affected by distortion in images.

Abstract translation: 在超声波诊断装置中，当产生复合图像时，基于通过划分被摄体而获得的各个段区域设定的声速来对要组合的所有超声图像（子帧）执行延迟校正。 由于该结构，超声波诊断装置可以通过空间复合或频率复合而产生高质量的复合图像，而不受图像中的失真的影响。

公开(公告)号：US20140187881A1

公开(公告)日：2014-07-03

申请号：US14196625

申请日：2014-03-04

Applicant: FUJIFILM Corporation

Inventor： Takaaki SAITO ,  Hiroshi YAMAGUCHI ,  Takayuki IIDA

IPC: A61B5/1455

CPC classification number: A61B5/14552 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/0638 ,  A61B1/0653 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/489 ,  G06T7/0012 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20212 ,  G06T2207/30101

Abstract: An oxygen saturation level of hemoglobin in blood is correctly acquired without lowering a frame rate. A subject body illuminated with white light W is imaged by a color CCD to obtain signals Bs1, Gs1 and Rs1. The subject body is illuminated with blue narrow band light BN of which absorption coefficient is changed by a change in the oxygen saturation level of the hemoglobin in blood, and imaged by the color CCD to obtain signals Bs2, Gs2 and Rs2. The signal Bs2 is divided by the signal Gs1 to determine a normalized signal Bs2/Gs1. The oxygen saturation level of blood vessels of the surface of body tissue is obtained according to the normalized signal Bs2/Gs1. The oxygen saturation level is visualized in a pseudo color, to form an oxygen saturation level image.

Abstract translation: 正确地获取血液中血红蛋白的氧饱和度水平，而不降低帧率。 用白光W照亮的被摄体被彩色CCD成像，得到信号Bs1，Gs1，Rs1。 用蓝色窄带光BN照射被摄体，其吸收系数由血液中血红蛋白的氧饱和度的变化而变化，并由彩色CCD成像，以获得信号Bs2，Gs2和Rs2。 信号Bs2由信号Gs1除以确定归一化信号Bs2 / Gs1。 根据归一化信号Bs2 / Gs1获得身体组织表面血管的氧饱和度水平。 氧饱和度水平以伪色显现，形成氧饱和度图像。

公开(公告)号：US20140221745A1

公开(公告)日：2014-08-07

申请号：US14250479

申请日：2014-04-11

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B1/05

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/0051 ,  A61B1/05 ,  A61B1/0669 ,  A61B1/0684 ,  A61B5/0084 ,  G02B23/2461 ,  G06T7/11 ,  G06T7/136 ,  G06T2207/10068 ,  G06T2207/10152 ,  H04N5/23245 ,  H04N5/23296 ,  H04N5/2351 ,  H04N9/045 ,  H04N2005/2255

Abstract: Only irregularities on the body tissue, such as a superficial microstructure or a hypertrophy, are made clear. A blue signal B, a green signal G, and a red signal R are obtained by imaging a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A superficial microstructure image 70 obtained by extracting the superficial microstructure P is displayed on a monitor 14.

Abstract translation: 仅清楚身体组织上的不规则，如表面微结构或肥大。 通过使用彩色CCD44对用白光W照明的被摄体进行拍摄来获得蓝色信号B，绿色信号G和红色信号R.基于这些信号B，G和R，将亮度信号I（（B + G + R）/ 3）。 提取超过亮度信号I的固定阈值Th1的像素区域作为表面微结构P，例如凹坑图案。 通过提取表面微结构P获得的表面微结构图像70显示在监视器14上。

公开(公告)号：US20140152790A1

公开(公告)日：2014-06-05

申请号：US14172729

申请日：2014-02-04

Applicant: FUJIFILM Corporation

Inventor： Takaaki SAITO ,  Hiroshi YAMAGUCHI ,  Takayuki IIDA

IPC: A61B1/00 ,  G06T5/00

CPC classification number: A61B1/00045 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0653 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/489 ,  G06T5/008 ,  G06T7/0012 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20221 ,  G06T2207/30028

Abstract: An observation object is imaged under irradiation with oxygen saturation level measurement light to obtain a first image signal, and the observation object is imaged under irradiation with white light to obtain a second image signal. A normal light image is produced from the second image signal. An oxygen saturation level is calculated from the first and second image signals. The calculated oxygen saturation level is imaged in an oxygen saturation image. By superimposing the normal light image on the oxygen saturation image, an emphasized oxygen saturation image is produced. In the emphasized oxygen saturation image, an abnormal area in which a calculation result of the oxygen saturation level is likely to be abnormal is emphasized by its brightness. The produced emphasized oxygen saturation image is displayed on a display device.

Abstract translation: 观察对象在用氧饱和度测量光照射下成像，以获得第一图像信号，并且在用白光照射下对观察对象进行成像以获得第二图像信号。 从第二图像信号产生正常的光图像。 从第一和第二图像信号计算出氧饱和度水平。 计算的氧饱和度水平在氧饱和度图像中成像。 通过将正常光图像叠加在氧饱和度图像上，产生强调的氧饱和度图像。 在强调的氧饱和度图像中，通过其亮度强调氧饱和度的计算结果可能异常的异常区域。 所产生的强调氧饱和度图像显示在显示装置上。

公开(公告)号：US20170319182A1

公开(公告)日：2017-11-09

申请号：US15659341

申请日：2017-07-25

Applicant: FUJIFILM Corporation

Inventor： Yasunori OHTA ,  Tsuyoshi TANABE ,  Noriaki IDA ,  Shin NAKATA ,  Hiroshi YAMAGUCHI

IPC: A61B8/00 ,  G01S7/52 ,  A61B8/14 ,  A61B8/08

CPC classification number: A61B8/585 ,  A61B8/14 ,  A61B8/4483 ,  A61B8/5207 ,  A61B8/5269 ,  A61B8/54 ,  G01S7/52049 ,  G01S7/52085

Abstract: An ultrasound diagnostic apparatus performs transmission and reception of ultrasonic waves for forming focal points used to set sound velocities at predetermined timing such that sound velocities having been set for all of respective segment regions established by diving a subject are all reset every predetermined number of frames. Owing to this configuration, it becomes possible for the ultrasound diagnostic apparatus to suitably reset sound velocities of ultrasonic waves in the subject and also reduce the amount of calculation for resetting sound velocities.

公开(公告)号：US20150282694A1

公开(公告)日：2015-10-08

申请号：US14696594

申请日：2015-04-27

Applicant: FUJIFILM CORPORATION

Inventor： Yoshinori MORIMOTO ,  Takumi DEJIMA ,  Hiroshi YAMAGUCHI

IPC: A61B1/00 ,  A61B17/04 ,  A61B5/00 ,  A61B5/1459 ,  A61B5/1455

CPC classification number: A61B1/00087 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/045 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/3132 ,  A61B5/1455 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/1459 ,  A61B5/4848 ,  A61B5/7278 ,  A61B5/7425 ,  A61B17/0469 ,  A61B17/12 ,  A61B2017/00057 ,  A61B2017/00296 ,  A61B2017/12004 ,  A61B2090/3937 ,  A61B2090/3991 ,  A61B2505/05 ,  A61B2562/0242

Abstract: The invention provides an endoscope system for the early detection of suture failure. Parts of the large intestine separated by the resection of a tumor are sutured by using a suturing member 167. A sutured portion is imaged. An oxygen saturation image 180 is generated by imaging the oxygen saturation of the sutured portion based on image information obtained by the imaging. The generated oxygen saturation image 180 is displayed on a display device 14. In the case of suture failure, a low oxygen region 180a is displayed in the oxygen saturation image.

Abstract translation: 本发明提供一种用于早期检测缝合失败的内窥镜系统。 通过使用缝合构件167缝合通过切除肿瘤分离的大肠的部分。成像缝合部分。 通过基于通过成像获得的图像信息成像缝合部分的氧饱和度来生成氧饱和度图像180。 生成的氧饱和度图像180显示在显示装置14上。在缝合线失效的情况下，在氧饱和度图像中显示低氧区180a。

公开(公告)号：US20140221744A1

公开(公告)日：2014-08-07

申请号：US14250120

申请日：2014-04-10

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B1/05

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/05 ,  A61B1/0653 ,  G06T5/50 ,  G06T7/11 ,  G06T7/136 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20221

Abstract: A blue signal B, a green signal G, and a red signal R are obtained by imagining a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a normal light image in which a wavelength component of a visible light region is included is generated. Based on the signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A microstructure enhancement image 72 is generated by combining the normal light image with a superficial microstructure image 70 obtained by extracting the superficial microstructure P. The generated microstructure and blood vessel enhancement image 72 is displayed on a monitor 14.

Abstract translation: 通过使用彩色CCD44想象用白光W照射的被摄体，获得蓝色信号B，绿色信号G和红色信号R.基于这些信号B，G和R，其中 生成可见光区域的波长分量。 基于信号B，G和R，生成表示被摄体的平均亮度的亮度信号I（（B + G + R）/ 3）。 提取超过亮度信号I的固定阈值Th1的像素区域作为表面微结构P，例如凹坑图案。 通过将正常光图像与通过提取表面微结构P获得的表面微结构图像70组合来生成微结构增强图像72.所产生的微结构和血管增强图像72显示在监视器14上。