公开(公告)号：US20140316195A1

公开(公告)日：2014-10-23

申请号：US14322670

申请日：2014-07-02

Applicant: FUJIFILM Corporation

Inventor： Toshihiko KAKU ,  Takayuki IIDA

IPC: A61B1/06

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/063 ,  A61B1/0646 ,  A61B1/0653 ,  G06T5/50 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/20212 ,  G06T2207/30004 ,  G06T2207/30101

Abstract: Broadband light BB and narrowband light NB are simultaneously irradiated to a subject. A blue signal B, a green signal G, and a red signal R are obtained by imaging the subject using a color CCD 33. A base image is generated from the signals B, G, and R of three colors. A B/G image having a B/G ratio is generated. A superficial blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or less than a boundary value Ls between the mucous membrane and the superficial blood vessel, from the B/G image. A medium-deep blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or greater than a boundary value Ld between the mucous membrane and the medium-deep blood vessel. The boundary values Ls and Ld differ depending on each observation mode.

Abstract translation: 宽带光BB和窄带光NB同时照射到被摄体。 蓝色信号B，绿色信号G和红色信号R是通过使用彩色CCD 33成像对象而获得的。从三种颜色的信号B，G和R生成基本图像。 产生具有B / G比率的B / G图像。 通过从B / G图像中提取B / G比等于或小于粘膜和浅表血管之间的边界值Ls的像素来获得浅表血管提取图像。 通过提取B / G比等于或大于粘膜和中深血管之间的边界值Ld的像素来获得中深血管提取图像。 边界值Ls和Ld根据每个观察模式而不同。

公开(公告)号：US20140221744A1

公开(公告)日：2014-08-07

申请号：US14250120

申请日：2014-04-10

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B1/05

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/05 ,  A61B1/0653 ,  G06T5/50 ,  G06T7/11 ,  G06T7/136 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20221

Abstract: A blue signal B, a green signal G, and a red signal R are obtained by imagining a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a normal light image in which a wavelength component of a visible light region is included is generated. Based on the signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A microstructure enhancement image 72 is generated by combining the normal light image with a superficial microstructure image 70 obtained by extracting the superficial microstructure P. The generated microstructure and blood vessel enhancement image 72 is displayed on a monitor 14.

Abstract translation: 通过使用彩色CCD44想象用白光W照射的被摄体，获得蓝色信号B，绿色信号G和红色信号R.基于这些信号B，G和R，其中 生成可见光区域的波长分量。 基于信号B，G和R，生成表示被摄体的平均亮度的亮度信号I（（B + G + R）/ 3）。 提取超过亮度信号I的固定阈值Th1的像素区域作为表面微结构P，例如凹坑图案。 通过将正常光图像与通过提取表面微结构P获得的表面微结构图像70组合来生成微结构增强图像72.所产生的微结构和血管增强图像72显示在监视器14上。

公开(公告)号：US20140100427A1

公开(公告)日：2014-04-10

申请号：US14104509

申请日：2013-12-12

Applicant: FUJIFILM CORPORATION

Inventor： Takaaki SAITO ,  Hiroshi YAMAGUCHI ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B1/04

CPC classification number: A61B1/0638 ,  A61B1/04 ,  A61B1/045 ,  A61B1/0646 ,  A61B1/0669 ,  A61B1/0684 ,  A61B5/0084 ,  A61B5/14503 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/7425

Abstract: First to fourth narrow band light N1 to N4 is sequentially applied to an observation object by rotating a rotary filter for special observation set in an optical path of a broad band light source. A blood vessel enhanced image in which a superficial blood vessel and a middle to deep-layer blood vessel are enhanced is produced based on reflection images of the first and fourth narrow band light N1 and N4. An oxygen saturation image, which images an oxygen saturation level of hemoglobin in blood, is produced based on reflection images of the second to fourth narrow band light N2 to N4. The produced blood vessel enhanced image and the oxygen saturation image are displayed side by side on a monitor.

Abstract translation: 通过旋转在宽带光源的光路中设置的特殊观察用旋转滤波器，将第一至第四窄带光N1至N4依次施加于观察对象物。 基于第一和第四窄带光N1和N4的反射图像，产生其中浅层血管和中间至深层血管增强的血管增强图像。 基于第二至第四窄带光N2至N4的反射图像产生对血液中血红蛋白的氧饱和度进行成像的氧饱和度图像。 产生的血管增强图像和氧饱和度图像并排显示在监视器上。

公开(公告)号：US20140187881A1

公开(公告)日：2014-07-03

申请号：US14196625

申请日：2014-03-04

Applicant: FUJIFILM Corporation

Inventor： Takaaki SAITO ,  Hiroshi YAMAGUCHI ,  Takayuki IIDA

IPC: A61B5/1455

CPC classification number: A61B5/14552 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/0638 ,  A61B1/0653 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/489 ,  G06T7/0012 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20212 ,  G06T2207/30101

Abstract: An oxygen saturation level of hemoglobin in blood is correctly acquired without lowering a frame rate. A subject body illuminated with white light W is imaged by a color CCD to obtain signals Bs1, Gs1 and Rs1. The subject body is illuminated with blue narrow band light BN of which absorption coefficient is changed by a change in the oxygen saturation level of the hemoglobin in blood, and imaged by the color CCD to obtain signals Bs2, Gs2 and Rs2. The signal Bs2 is divided by the signal Gs1 to determine a normalized signal Bs2/Gs1. The oxygen saturation level of blood vessels of the surface of body tissue is obtained according to the normalized signal Bs2/Gs1. The oxygen saturation level is visualized in a pseudo color, to form an oxygen saturation level image.

Abstract translation: 正确地获取血液中血红蛋白的氧饱和度水平，而不降低帧率。 用白光W照亮的被摄体被彩色CCD成像，得到信号Bs1，Gs1，Rs1。 用蓝色窄带光BN照射被摄体，其吸收系数由血液中血红蛋白的氧饱和度的变化而变化，并由彩色CCD成像，以获得信号Bs2，Gs2和Rs2。 信号Bs2由信号Gs1除以确定归一化信号Bs2 / Gs1。 根据归一化信号Bs2 / Gs1获得身体组织表面血管的氧饱和度水平。 氧饱和度水平以伪色显现，形成氧饱和度图像。

公开(公告)号：US20140221745A1

公开(公告)日：2014-08-07

申请号：US14250479

申请日：2014-04-11

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/06 ,  A61B1/05

CPC classification number: A61B1/0638 ,  A61B1/00009 ,  A61B1/0051 ,  A61B1/05 ,  A61B1/0669 ,  A61B1/0684 ,  A61B5/0084 ,  G02B23/2461 ,  G06T7/11 ,  G06T7/136 ,  G06T2207/10068 ,  G06T2207/10152 ,  H04N5/23245 ,  H04N5/23296 ,  H04N5/2351 ,  H04N9/045 ,  H04N2005/2255

Abstract: Only irregularities on the body tissue, such as a superficial microstructure or a hypertrophy, are made clear. A blue signal B, a green signal G, and a red signal R are obtained by imaging a subject illuminated with white light W using a color CCD 44. Based on these signals B, G, and R, a brightness signal I ((B+G+R)/3) showing the average brightness of the subject is generated. A pixel region exceeding the fixed threshold value Th1 of the brightness signal I is extracted as a superficial microstructure P, such as a pit pattern. A superficial microstructure image 70 obtained by extracting the superficial microstructure P is displayed on a monitor 14.

Abstract translation: 仅清楚身体组织上的不规则，如表面微结构或肥大。 通过使用彩色CCD44对用白光W照明的被摄体进行拍摄来获得蓝色信号B，绿色信号G和红色信号R.基于这些信号B，G和R，将亮度信号I（（B + G + R）/ 3）。 提取超过亮度信号I的固定阈值Th1的像素区域作为表面微结构P，例如凹坑图案。 通过提取表面微结构P获得的表面微结构图像70显示在监视器14上。

公开(公告)号：US20140152790A1

公开(公告)日：2014-06-05

申请号：US14172729

申请日：2014-02-04

Applicant: FUJIFILM Corporation

Inventor： Takaaki SAITO ,  Hiroshi YAMAGUCHI ,  Takayuki IIDA

IPC: A61B1/00 ,  G06T5/00

CPC classification number: A61B1/00045 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0653 ,  A61B5/14551 ,  A61B5/1459 ,  A61B5/489 ,  G06T5/008 ,  G06T7/0012 ,  G06T2207/10016 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/20221 ,  G06T2207/30028

Abstract: An observation object is imaged under irradiation with oxygen saturation level measurement light to obtain a first image signal, and the observation object is imaged under irradiation with white light to obtain a second image signal. A normal light image is produced from the second image signal. An oxygen saturation level is calculated from the first and second image signals. The calculated oxygen saturation level is imaged in an oxygen saturation image. By superimposing the normal light image on the oxygen saturation image, an emphasized oxygen saturation image is produced. In the emphasized oxygen saturation image, an abnormal area in which a calculation result of the oxygen saturation level is likely to be abnormal is emphasized by its brightness. The produced emphasized oxygen saturation image is displayed on a display device.

Abstract translation: 观察对象在用氧饱和度测量光照射下成像，以获得第一图像信号，并且在用白光照射下对观察对象进行成像以获得第二图像信号。 从第二图像信号产生正常的光图像。 从第一和第二图像信号计算出氧饱和度水平。 计算的氧饱和度水平在氧饱和度图像中成像。 通过将正常光图像叠加在氧饱和度图像上，产生强调的氧饱和度图像。 在强调的氧饱和度图像中，通过其亮度强调氧饱和度的计算结果可能异常的异常区域。 所产生的强调氧饱和度图像显示在显示装置上。

公开(公告)号：US20150216400A1

公开(公告)日：2015-08-06

申请号：US14686687

申请日：2015-04-14

Applicant: FUJIFILM Corporation

Inventor： Takayuki IIDA ,  Toshihiko Kaku ,  Hiroshi Yamaguchi ,  Takaaki Saito

IPC: A61B1/06 ,  A61B1/00 ,  A61B5/00 ,  A61B1/04

CPC classification number: A61B1/0638 ,  A61B1/00006 ,  A61B1/00009 ,  A61B1/00045 ,  A61B1/04 ,  A61B1/063 ,  A61B1/0653 ,  A61B1/0661 ,  A61B5/489 ,  A61B5/7257

Abstract: An endoscopic device that irradiates a plurality of illuminating lights having different spectrums from each other onto a subject at a front edge of an endoscope inserting module and captures the subject to obtain an observation image, includes an illuminating module that generates the plurality of illuminating lights, an imaging module that captures the subject and outputs an image signal of the observation image, a light intensity ratio control module that controls the illuminating module to irradiate the plurality of illuminating lights onto the subject with a set light intensity ratio by setting the light intensity ratio of the plurality of illuminating lights for every observation image, and a color tone correcting module that corrects the color tone of the image signal so as to obtain the observation image with substantially a same color tone even though the light intensity ratio is changed.

Abstract translation: 一种内窥镜装置，其将具有不同光谱的多个照明光照射到内窥镜插入模块的前端的被检体上并捕获被检体以获得观察图像，所述内窥镜装置包括产生所述多个照明光的照明模块， 拍摄对象并输出观察图像的图像信号的成像模块;光强度比控制模块，其通过设定光强度比控制照明模块以设定的光强度比将多个照明光照射到被摄体上 对于每个观察图像的多个照明灯，以及色调校正模块，其校正图像信号的色调，以便即使光强比改变，也获得具有基本相同色调的观察图像。

公开(公告)号：US20140316283A1

公开(公告)日：2014-10-23

申请号：US14321116

申请日：2014-07-01

Applicant: FUJIFILM Corporation

Inventor： Toshihiko KAKU ,  Takayuki IIDA

IPC: A61B5/00 ,  G06K9/00 ,  G06T11/00 ,  A61B1/06 ,  A61B5/02

CPC classification number: A61B5/0084 ,  A61B1/00009 ,  A61B1/0005 ,  A61B1/043 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B5/02007 ,  G06K9/0014 ,  G06T7/0012 ,  G06T7/90 ,  G06T11/001 ,  G06T2207/10024 ,  G06T2207/10068 ,  G06T2207/10152 ,  G06T2207/30101

Abstract: Even if the ratio between blue and green components of illumination light is changed, a plurality of types of blood vessels at different depths are reliably distinguished. A blue signal B, a green signal G, a red signal R is obtained by imaging the subject using a color CCD 44. A B/G image having a B/G ratio is generated. A superficial blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or less than a boundary value Ls between the mucous membrane and the superficial blood vessel, from the B/G image. A medium-deep blood vessel extraction image is obtained by extracting a pixel, in which the B/G ratio is equal to or greater than a boundary value Ld between the mucous membrane and the medium-deep blood vessel. The boundary values Ls and Ld differ depending on the light amount ratio.

Abstract translation: 即使照明光的蓝色和绿色成分之间的比例发生变化，也可以区分不同深度的多种类型的血管。 通过使用彩色CCD44成像对象，获得蓝色信号B，绿色信号G，红色信号R.产生具有B / G比的B / G图像。 通过从B / G图像中提取B / G比等于或小于粘膜和浅表血管之间的边界值Ls的像素来获得浅表血管提取图像。 通过提取B / G比等于或大于粘膜和中深血管之间的边界值Ld的像素获得中深血管提取图像。 边界值Ls和Ld根据光量比而不同。

公开(公告)号：US20140228638A1

公开(公告)日：2014-08-14

申请号：US14258534

申请日：2014-04-22

Applicant: FUJIFILM CORPORATION

Inventor： Tsuyoshi ASHIDA ,  Jin MURAYAMA ,  Takayuki NAKAMURA ,  Hidetoshi HIRATA ,  Kazuyoshi HARA ,  Shinichi YAMAKAWA ,  Takayuki IIDA

IPC: A61B1/00 ,  H04N5/361 ,  H04N5/374 ,  A61B1/06

CPC classification number: A61B1/00009 ,  A61B1/0002 ,  A61B1/05 ,  A61B1/0661 ,  A61B1/128 ,  H04N5/361 ,  H04N5/374

Abstract: An electronic endoscope system is composed of an electronic endoscope, a light source apparatus, and a temperature converter. The electronic endoscope has a CMOS sensor in a distal portion of an insert section to be inserted into a patient's body cavity. Illumination light from the light source apparatus is applied to the body cavity through the distal portion. The temperature converter obtains an average pixel value of an optical black (OB) region out of an imaging signal from the CMOS sensor, and converts the average OB pixel value into a temperature of the CMOS sensor on a frame-by-frame basis with the use of data in a temperature conversion table. The table represents a relationship between the average OB pixel value and the temperature of the CMOS sensor. Light quantity of the illumination light is adjusted in accordance with the temperature of the CMOS sensor to prevent deterioration of image quality.

Abstract translation: 电子内窥镜系统由电子内窥镜，光源装置和温度转换器构成。 电子内窥镜在插入部分的远端部分中具有CMOS传感器，以插入患者的体腔中。 来自光源装置的照明光通过远端部分施加到体腔。 温度转换器从CMOS传感器的成像信号中获得光学黑（OB）区域的平均像素值，并且将平均OB像素值逐帧地转换为CMOS传感器的温度， 在温度转换表中使用数据。 该表表示CMOS传感器的平均OB像素值和温度之间的关系。 根据CMOS传感器的温度来调节照明光的光量，以防止图像质量的劣化。

公开(公告)号：US20140221794A1

公开(公告)日：2014-08-07

申请号：US14251043

申请日：2014-04-11

Applicant: FUJIFILM Corporation

Inventor： Hiroshi YAMAGUCHI ,  Satoshi OZAWA ,  Takayuki IIDA

IPC: A61B1/00 ,  A61B1/06

CPC classification number: A61B1/00009 ,  A61B1/0051 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0653 ,  A61B1/0661 ,  A61B1/0684 ,  A61B5/0084 ,  F04C2270/041

Abstract: The visibility of irregularities on the body tissue, such as a superficial microstructure or hypertrophy, is improved. Excitation light EL is emitted to a phosphor to excite and emit white light W. High absorption wavelength cut light is generated by removing components in high absorption wavelength bands A1 and A2, in which the absorption coefficient of hemoglobin in the blood is high, from the white light using a high absorption wavelength rejection filter. The subject is illuminated with the high absorption wavelength cut light, and image light of the reflected light is captured by a color CCD. A microstructure image is generated based on a signal Bp output from the B pixel of the CCD. In this microstructure image, the display of superficial microvessels is suppressed. Accordingly, the visibility of superficial microstructures, such as a pit pattern, is relatively improved.

Abstract translation: 改善身体组织上的不规则性（例如表面微结构或肥大）的可视性。 激发光EL被发射到荧光体以激发并发出白光W.通过从高吸收波长带A1和A2中除去血液中血红蛋白的吸收系数高的成分，从而产生高吸收波长切割光 白光采用高吸收波长抑制滤光片。 用高吸收波长切割光照射被摄体，并且通过彩色CCD捕获反射光的图像光。 基于从CCD的B像素输出的信号Bp生成微结构图像。 在该微结构图像中，抑制了表面微血管的显示。 因此，诸如凹坑图案的表面微结构的可视性相对提高。