公开(公告)号：US06365789B2

公开(公告)日：2002-04-02

申请号：US09843305

申请日：2001-04-25

申请人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

发明人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

IPC分类号： C07C3118

CPC分类号： A23G3/346 ,  A23L27/34 ,  A61K9/2018 ,  C07C31/26 ,  C07H3/06

摘要： The invention relates to a pulverulent sorbitol, characterized in that it exhibits a hygroscopicity value, determined according to a test A, of less than 2%, preferably of less than 1.7%, and a specific surface, determined according to the BET method, at least equal to 2 m2/g, preferably at least equal to 2.2 m2/g, and also relates to its process of preparation. The invention also relates to compositions intended in particular for the food and pharmaceutical fields and to the use of the said pulverulent sorbitol in the preparation of tablets exhibiting a > texture.

摘要翻译： 本发明涉及一种粉状山梨糖醇，其特征在于其根据试验A显示的吸湿性值小于2％，优选小于1.7％，并且根据BET法测定的比表面积 至少等于2m 2 / g，优选至少等于2.2m 2 / g，并且还涉及其制备方法。 本发明还涉及特别用于食品和药物领域的组合物，以及所述粉状山梨糖醇在制备呈现“口味平滑”质地的片剂中的用途。

公开(公告)号：US06387402B1

公开(公告)日：2002-05-14

申请号：US09843304

申请日：2001-04-25

申请人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

发明人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

IPC分类号： A61K920

CPC分类号： A23G3/346 ,  A23L27/34 ,  A61K9/2018 ,  C07C31/26 ,  C07H3/06

摘要： The invention relates to a pulverulent sorbitol, characterized in that it exhibits a hygroscopicity value, determined according to a test A, of less than 2%, preferably of less than 1.7%, and a specific surface, determined according to the BET method, at least equal to 2 m2/g, preferably at least equal to 2.2 m2/g, and also relates to its process of preparation. The invention also relates to compositions intended in particular for the food and pharmaceutical fields and to the use of the said pulverulent sorbitol in the preparation of tablets exhibiting a > texture.

公开(公告)号：US06274778B1

公开(公告)日：2001-08-14

申请号：US09457536

申请日：1999-12-09

申请人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

发明人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre ,  Frédéric Bouvier

IPC分类号： C07C3118

CPC分类号： A23G3/346 ,  A23L27/34 ,  A61K9/2018 ,  C07C31/26 ,  C07H3/06

摘要： The invention relates to a pulverulent sorbitol, characterized in that it exhibits a hygroscopicity value, determined according to a test A, of less than 2%, preferably of less than 1.7%, and a specific surface, determined according to the BET method, at least equal to 2 m2/g, preferably at least equal to 2.2 m2/g, and also relates to its process of preparation. The invention also relates to compositions intended in particular for the food and pharmaceutical fields and to the use of the said pulverulent sorbitol in the preparation of tablets exhibiting a > texture.

摘要翻译： 本发明涉及一种粉状山梨糖醇，其特征在于其根据试验A显示的吸湿性值小于2％，优选小于1.7％，并且根据BET法测定的比表面积 至少等于2m 2 / g，优选至少等于2.2m 2 / g，并且还涉及其制备方法。 本发明还涉及特别用于食品和药物领域的组合物，以及所述粉状山梨糖醇在制备呈现“口味平滑”质地的片剂中的用途。

公开(公告)号：US06451122B1

公开(公告)日：2002-09-17

申请号：US09464024

申请日：1999-12-15

申请人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre

发明人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre

IPC分类号： C13K1300

CPC分类号： A23G1/40 ,  A23G3/42 ,  A23L27/33 ,  C13K1/00 ,  C13K1/10

摘要： The invention relates to a dextrose in powder form, characterized in that it has a dextrose content at least equal to 99%, a &agr; crystalline form content at least equal to 95%, a water content at most equal to 1% and a compressibility, determined according to a test A, at least equal to 80 N, preferably in the range 100 N and 200 N. The invention also relates to the use of said dextrose in powder form as a sweetener or excipient, particularly in food or pharmaceutical compositions, for example, for the preparation of confectionery or of tablets to be sucked, chewed, dissolved or swallowed.

摘要翻译： 本发明涉及粉末形式的葡萄糖，其特征在于其具有至少等于99％的葡萄糖含量，至少等于95％的α结晶形式含量，至多等于1％的水含量和可压缩性， 根据测试A确定，至少等于80N，优选在100N和200N的范围内。本发明还涉及以粉末形式的所述葡萄糖作为甜味剂或赋形剂，特别是在食品或药物组合物中的用途， 例如，用于制备糖果或要被吸，咀嚼，溶解或吞咽的片剂。

公开(公告)号：US06527868B2

公开(公告)日：2003-03-04

申请号：US10210169

申请日：2002-08-01

申请人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre

发明人： Franck Moraly ,  Erik Labergerie ,  José Lis ,  Philippe Lefevre

IPC分类号： C13K1300

CPC分类号： C13K1/00 ,  C07H1/00

摘要： The invention relates to a dextrose in powder form, characterised in that it has a dextrose content at least equal to 99%, an &agr; crystalline form content at least equal to 95%, a water content at most equal to 1% and a compressibility, determined according to a test A, at least equal to 80 N, preferably in the range 100 N and 200 N. The invention also relates to the use of said dextrose in powder form as a sweetener or excipient, particularly in food or pharmaceutical compositions, for example, for the preparation of confectionery or of tablets to be sucked, chewed, dissolved or swallowed.

摘要翻译： 本发明涉及粉末形式的葡萄糖，其特征在于其具有至少等于99％的葡萄糖含量，至少等于95％的α晶形含量，至多等于1％的水含量和可压缩性， 根据测试A确定，至少等于80N，优选在100N和200N的范围内。本发明还涉及以粉末形式的所述葡萄糖作为甜味剂或赋形剂，特别是在食品或药物组合物中的用途， 例如，用于制备糖果或要被吸，咀嚼，溶解或吞咽的片剂。

公开(公告)号：US06743447B2

公开(公告)日：2004-06-01

申请号：US09819496

申请日：2001-03-28

申请人： Erik Labergerie ,  Philippe Lefevre ,  José Lis

发明人： Erik Labergerie ,  Philippe Lefevre ,  José Lis

IPC分类号： A61K914

CPC分类号： C07C31/26 ,  A61K9/2018 ,  A61K9/4858 ,  A61K47/26

摘要： The present invention concerns pulverulent mannitol characterized in that it has an average diameter of between 60 and 200 &mgr;m, preferably of between 80 and 180 &mgr;m, a packed density, determined according to a Test A, of between 0.65 and 0.85 g/ml, preferably of between 0.7 and 0.8 g/ml and a flow factor of at least 60, preferably of between 60 and 90a process for obtaining and using the said pulverulent mannitol as an excipient in preparations intended in particular for the pharmaceutical field, and especially as a powder for filling hard capsules.

摘要翻译： 本发明涉及粉状甘露醇，其特征在于其平均直径为60至200μm，优选为80至180μm，根据测试A确定的填充密度为0.65至0.85g / ml，优选为 在0.7至0.8g / ml之间的流动系数和至少60，优选在60和90a之间的流动系数，用于在特别用于制药领域的制剂中获得和使用所述粉状甘露糖醇作为赋形剂，特别是作为粉末 用于填充硬胶囊。

公开(公告)号：US08101806B2

公开(公告)日：2012-01-24

申请号：US12375464

申请日：2007-07-23

申请人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  José Lis

发明人： Pierrick Duflot ,  Baptiste Boit ,  Philippe Lefevre ,  José Lis

IPC分类号： C07C31/18 ,  A23L1/236

CPC分类号： C07C31/26 ,  A23L27/34 ,  A23L29/37 ,  A23P10/20 ,  A61K9/1623 ,  A61K9/2018 ,  Y10T428/2982

摘要： The present invention relates to a granulated sorbitol of essentially γ crystalline form and having a high sorbitol content, characterized in that it has a specific surface area, determined according to the BET method, of greater than or equal to 2 m2/g, preferably of between 2.2 and 4 m2/g, and even more preferably of between 2.5 and 3.5 m2/g, a compressibility of between 200 and 400 N, preferably of between 250 and 350 N, and a volume-average diameter, measured by laser diffraction particle sizing using a dry-system module, of between 260 and 1000 μm, preferably of between 260 and 500 μm, and even more preferably of between 260 and 350 μm.

摘要翻译： 本发明涉及一种基本为γ晶形并具有高山梨糖醇含量的颗粒状山梨糖醇，其特征在于其具有根据BET法测定的比表面积大于或等于2m 2 / g，优选为 在2.2至4m 2 / g之间，甚至更优选2.5至3.5m 2 / g的压缩性，200至400N之间的压缩性，优选250至350N，以及通过激光衍射颗粒测量的体积平均直径 使用干式系统模块的尺寸在260和1000μm之间，优选在260和500μm之间，甚至更优选在260和350μm之间。

公开(公告)号：US06881432B2

公开(公告)日：2005-04-19

申请号：US09735092

申请日：2000-12-12

申请人： Erik La Bergerie ,  Philippe Lefevre ,  José Lis

发明人： Erik La Bergerie ,  Philippe Lefevre ,  José Lis

IPC分类号： A01G1/00 ,  A23G3/00 ,  A23G3/34 ,  A23L1/09 ,  A23L1/236 ,  A23L1/30 ,  C07H3/02 ,  C13K1/10 ,  C13K13/00

CPC分类号： C13K1/10 ,  A23G3/346 ,  A23G2200/06 ,  A23L27/33

摘要： The invention relates to a dextrose hydrate in powder form, having a dextrose content at least equal to 98%, an α crystalline form content at least equal to 95%, a water content greater than 1%, a compressibility determined according to a test A, at least equal to 70 N. The invention also relates to a process for the preparation thereof and to the use of said dextrose hydrate in powder form as a sweetener, osmotic agent, nutrient or excipient, particularly in compositions intended for the food, pharmaceutical, chemical and agrochemical sectors.

摘要翻译： 本发明涉及粉末形式的葡萄糖水合物，其葡萄糖含量至少等于98％，α晶形含量至少等于95％，水含量大于1％，根据试验A确定的压缩性 至少等于70N。本发明还涉及其制备方法以及粉末形式的所述葡萄糖水合物作为甜味剂，渗透剂，营养物或赋形剂，特别是在用于食品，药物的组合物中的用途 ，化工和农化部门。

公开(公告)号：US20120164267A1

公开(公告)日：2012-06-28

申请号：US13393619

申请日：2010-08-06

申请人： Baptiste Boit ,  Philippe Lefevre ,  Jose Lis ,  Dominique Ortiz De Zarate

发明人： Baptiste Boit ,  Philippe Lefevre ,  Jose Lis ,  Dominique Ortiz De Zarate

IPC分类号： A23G4/06

CPC分类号： A23G4/025 ,  A23G4/062 ,  A23G4/10 ,  A23G2210/00 ,  A23V2002/00 ,  A23V2200/22 ,  A23V2200/254 ,  A23V2250/5118 ,  A23V2250/5114

摘要： A chewing gum production method includes a step in which the ingredients are mixed together, a mixture-extrusion step, a dusting step using a dusting powder, a sheeting step and a shaping/cutting step. The dusting powder includes a powder composition of agglomerates of crystals, the powder composition including at least one polyol. The resulting chewing gum is also described.

摘要翻译： 口香糖生产方法包括将成分混合在一起的步骤，混合物挤出步骤，使用除尘粉末的粉尘步骤，片材步骤和成型/切割步骤。 粉尘粉末包括结晶附聚物的粉末组合物，粉末组合物包含至少一种多元醇。 还描述了所得到的口香糖。

公开(公告)号：US20110114532A1

公开(公告)日：2011-05-19

申请号：US13002721

申请日：2009-07-15

申请人： Alain Francois ,  Philippe Lefevre ,  Denis Simon

发明人： Alain Francois ,  Philippe Lefevre ,  Denis Simon

IPC分类号： B65D85/42 ,  B29C39/38

CPC分类号： B29C39/003 ,  A61K9/006 ,  B29C33/0016 ,  B29K2105/0035

摘要： A method of manufacturing a film (6) includes the following steps: a) a film-forming mixture containing at least one film-forming agent is prepared; b) a dose of the mixture is deposited in a cell (4) of a cellular substrate (2), the mixture having a viscosity ranging from 1 to 8000 mPa·s at the temperature of the film-forming mixture during the deposition; c) the mixture is cured so as to obtain a film (6); and d) the cell (4) is closed off by a hermetic sealing element (3). A device (1) especially suitable for the method and a device intended to implement the method are also described.

摘要翻译： 制备薄膜（6）的方法包括以下步骤：a）制备含有至少一种成膜剂的成膜混合物; b）将一定量的混合物沉积在多孔基材（2）的电池（4）中，该混合物在沉积期间在成膜混合物的温度下具有1至8000mPa·s的粘度; c）将混合物固化以获得薄膜（6）; 和d）电池（4）由气密密封元件（3）封闭。 还描述了特别适用于该方法的装置（1）和旨在实现该方法的装置。