公开(公告)号：US09681925B2

公开(公告)日：2017-06-20

申请号：US11107640

申请日：2005-04-15

Applicant: Fred S. Azar ,  Ali Khamene ,  Frank Sauer ,  Sebastian Vogt

Inventor： Fred S. Azar ,  Ali Khamene ,  Frank Sauer ,  Sebastian Vogt

IPC: A61B5/05 ,  A61B90/00 ,  A61B34/20 ,  A61B90/11 ,  A61B34/10

CPC classification number: A61B90/36 ,  A61B34/10 ,  A61B34/20 ,  A61B90/11 ,  A61B90/361 ,  A61B2034/107 ,  A61B2090/365

Abstract: A system and method for instrument placement using an image based navigation system is disclosed. A target of interest is identified in a medical image of a patient. An image plane is displayed that goes through a center of the target. The image plane has a configurable orientation. The image plane is used to select a path for an instrument from a position on the patient's skin to the center of the target. A trajectory plane is viewed from a tip of the instrument to the center of the target. The trajectory plane reflects an orientation of the instrument. A particular trajectory plane is selected that is representative of a desired orientation of the instrument. An image of the particular trajectory plane is frozen. The instrument can then be inserted using a virtual guide and is navigated toward the target.

公开(公告)号：US08312796B2

公开(公告)日：2012-11-20

申请号：US11693014

申请日：2007-03-29

Applicant: Stefan Künkel ,  Frank Sauer ,  Volker Schneider

Inventor： Stefan Künkel ,  Frank Sauer ,  Volker Schneider

IPC: B26D7/06 ,  B23D19/00 ,  B27B5/18

CPC classification number: G01N1/06 ,  Y10T83/202 ,  Y10T83/6492 ,  Y10T83/6508

Abstract: The present invention relates to a microtome (1) having functional regions to be operated manually, in particular a sample holder (2), a cutting device (3), a section removal system (4), and a section collection pan (5). A microtome (1) is described in which the particularly firm contact or adhesion of sectioning waste fragments and, in particular, of thin sections can be at least largely avoided. For this purpose, the microtome (1) according to the present invention is characterized in that the components of the microtome (1) that can be brought into contact with paraffin sections are embodied in electrically conductive fashion.

Abstract translation: 本发明涉及具有手动操作的功能区域的切片机（1），特别是样品架（2），切割装置（3），部分移除系统（4）和部分收集盘（5） 。 描述了一种切片机（1），其中可以至少在很大程度上避免切片废料碎片，特别是薄部分的特别牢固的接触或粘附。 为此，根据本发明的切片机（1）的特征在于，与石蜡切片接触的切片机（1）的部件以导电方式实现。

公开(公告)号：US08244332B2

公开(公告)日：2012-08-14

申请号：US11292338

申请日：2005-12-01

Applicant: Fred S. Azar ,  Ali Khamene ,  Frank Sauer ,  Bruce Tromberg ,  Albert Cerussi

Inventor： Fred S. Azar ,  Ali Khamene ,  Frank Sauer ,  Bruce Tromberg ,  Albert Cerussi

IPC: A61B6/00

CPC classification number: A61B5/4312 ,  A61B5/0091 ,  A61B34/20 ,  A61B2034/105 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/373 ,  G01N21/359 ,  G01N21/474 ,  G01N21/4795 ,  G01N2021/1787 ,  G01N2021/4745 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/0691 ,  G01N2201/08

Abstract: A diffuse optical spectroscopy system comprises a laser breast scanner, a handheld probe connected to the laser breast scanner for scanning a breast, and a tracking device coupled to the handheld probe, wherein the tracking device determines locations of the handheld probe relative to the breast. The tracking device comprises a magnetic tracking device, an optical tracking device or a laser tracking device.

Abstract translation: 扩散光谱系统包括激光乳房扫描器，连接到用于扫描乳房的激光乳房扫描器的手持式探头以及耦合到手持探针的跟踪装置，其中跟踪装置确定手持式探针相对于乳房的位置。 跟踪装置包括磁跟踪装置，光学跟踪装置或激光跟踪装置。

公开(公告)号：US08109533B2

公开(公告)日：2012-02-07

申请号：US13006254

申请日：2011-01-13

Applicant: Frank Sauer

Inventor： Frank Sauer

IPC: B60R21/26

CPC classification number: B60R21/239 ,  B60R21/201 ,  B60R21/2338 ,  B60R2021/23384 ,  B60R2021/2395 ,  B60R2021/26017 ,  Y10S102/704

Abstract: The invention relates to an airbag module for a motor vehicle, comprising a gas sack package comprising a gas sack, an additional moveable element configured and provided to influence a state variable of the airbag, and a gas-tight protective covering that defines an inner space of the gas sack package, wherein the gas sack and the moveable element are arranged in said inner space, and a separate movement generating device configured and provided to move the moveable element. According to the invention, the movement generating device is arranged outside the inner space of the airbag package.

Abstract translation: 本发明涉及一种用于机动车辆的气囊组件，其包括气袋，其包括气囊，构造和提供以用于影响气囊的状态变量的附加可移动元件，以及限定内部空间的气密保护罩 其中气囊和可移动元件布置在所述内部空间中，并且分离的运动产生装置被配置和设置成移动可移动元件。 根据本发明，运动产生装置布置在气囊包装的内部空间的外侧。

公开(公告)号：US07986822B2

公开(公告)日：2011-07-26

申请号：US11734395

申请日：2007-04-12

Applicant: Andrew F Hall ,  Ashraf Mohamed ,  Teri Moore ,  Esther Rohm ,  Frank Sauer

Inventor： Andrew F Hall ,  Ashraf Mohamed ,  Teri Moore ,  Esther Rohm ,  Frank Sauer

IPC: G06K9/00

CPC classification number: G06T7/0012 ,  A61B6/4441 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  G06T5/50 ,  G06T7/62 ,  G06T2207/10116 ,  G06T2207/30101

Abstract: A method of assessing rupture risk of an aneurysm from time-resolved images includes injecting a contrast enhancing agent into a patient with an aneurysm, using an electrocardiogram (ECG) signal to trigger an image acquisition run, wherein a sequence of 2D X-ray fluoroscopic images is acquired along with a corresponding ECG signal value, rotating a C-arm attaching the X-ray fluoroscopic imaging apparatus during said image acquisition run, wherein the images in said X-ray fluoroscopic image sequence are acquired from a rotating viewpoint, sorting the images in said X-ray fluoroscopic image sequence into time windows of the cardiac cycle based on the ECG signal, and constructing one or more 3-dimensional (3D) angiography image volumes of said aneurysm from said 2D fluoroscopic image sequence.

Abstract translation: 从时间分辨图像中评估动脉瘤的破裂风险的方法包括使用心电图（ECG）信号将具有动脉瘤的对比度增强剂注射到患者中以触发图像采集运行，其中2D X射线透视 获取图像与相应的ECG信号值，在所述图像采集运行期间旋转安装X射线透视成像装置的C形臂，其中从旋转视点获取所述X射线透视图像序列中的图像，对 所述X射线透视图像序列中的图像基于ECG信号进入心脏周期的时间窗口，以及从所述2D透视图像序列构建所述动脉瘤的一个或多个三维（3D）血管造影图像体积。

公开(公告)号：US07822254B2

公开(公告)日：2010-10-26

申请号：US11695096

申请日：2007-04-02

Applicant: Liron Yatziv ,  Yiyong Sun ,  Chenyang Xu ,  Frank Sauer

Inventor： Liron Yatziv ,  Yiyong Sun ,  Chenyang Xu ,  Frank Sauer

IPC: G06K9/00

CPC classification number: G06T7/30 ,  G06T2207/30004

Abstract: A computer-implemented method is disclosed for comparing three dimensional (3D) digital medical images. The method uses a reference MPR to position subsequent MPRs in one or more other 3D digital medical images so their content matches the reference MPR. The matched MPRs may then be used by a medical professional to diagnose a patient condition. The ability to quickly and automatically position matching MPRs for multiple 3D images eases the medical staff workload and shortens diagnostics time. Matching MPRs provides an effective way to view the 3D volumes for anatomical changes over time and to monitor medical conditions such as stenosis and tumors.

Abstract translation: 公开了一种用于比较三维（3D）数字医学图像的计算机实现的方法。 该方法使用参考MPR将一个或多个其他3D数字医学图像中的后续MPR定位，使得其内容与参考MPR匹配。 然后，医疗专业人员可以使用匹配的MPR来诊断患者状况。 快速，自动地为多个3D图像定位匹配的MPR的能力可以减轻医务人员的工作量，缩短诊断时间。 匹配MPR提供了一种有效的方式来查看3D体积，以便随着时间的推移进行解剖学变化，并监测诸如狭窄和肿瘤之类的医学状况。

公开(公告)号：US07711405B2

公开(公告)日：2010-05-04

申请号：US10833742

申请日：2004-04-28

Applicant: Ali Khamene ,  Frank Sauer

Inventor： Ali Khamene ,  Frank Sauer

IPC: A61B5/05

CPC classification number: G01R33/56 ,  G01R33/5608

Abstract: A system and method for registering pre-operative magnetic resonance (MR) images with intra-operative MR images is disclosed. A pre-operative MR image of an object is received. A set of intra-operative MR images of the object is received. The pre-operative MR image is rigidly registered with the initial intra-operative MR image. The subsequent set of intra-operative images is deformably registered. The pre-operative MR image undergoes both rigid and deformation transformation to match specification of each image with in intra-operative MR image set.

Abstract translation: 公开了一种用于将术前磁共振（MR）图像与术中MR图像对准的系统和方法。 接收对象的术前MR图像。 接收对象的一组手术中MR图像。 手术前MR图像与初始手术中MR图像刚性对齐。 随后的一组术中图像可变形地记录。 手术前MR图像经历刚性和变形变换，以在手术中的MR图像组中匹配每个图像的规格。

公开(公告)号：US20090067568A1

公开(公告)日：2009-03-12

申请号：US11734395

申请日：2007-04-12

Applicant: Andrew F. Hall ,  Ashraf Mohamed ,  Teri Moore ,  Esther Rohm ,  Frank Sauer

Inventor： Andrew F. Hall ,  Ashraf Mohamed ,  Teri Moore ,  Esther Rohm ,  Frank Sauer

IPC: A61B6/00 ,  G06K9/00

CPC classification number: G06T7/0012 ,  A61B6/4441 ,  A61B6/503 ,  A61B6/504 ,  A61B6/541 ,  G06T5/50 ,  G06T7/62 ,  G06T2207/10116 ,  G06T2207/30101

Abstract: A method of assessing rupture risk of an aneurysm from time-resolved images includes injecting a contrast enhancing agent into a patient with an aneurysm, using an electrocardiogram (ECG) signal to trigger an image acquisition run, wherein a sequence of 2D X-ray fluoroscopic images is acquired along with a corresponding ECG signal value, rotating a C-arm attaching the X-ray fluoroscopic imaging apparatus during said image acquisition run, wherein the images in said X-ray fluoroscopic image sequence are acquired from a rotating viewpoint, sorting the images in said X-ray fluoroscopic image sequence into time windows of the cardiac cycle based on the ECG signal, and constructing one or more 3-dimensional (3D) angiography image volumes of said aneurysm from said 2D fluoroscopic image sequence.

Abstract translation: 从时间分辨图像中评估动脉瘤的破裂风险的方法包括使用心电图（ECG）信号将具有动脉瘤的对比度增强剂注射到患者中以触发图像采集运行，其中2D X射线透视 获取图像与相应的ECG信号值，在所述图像采集运行期间旋转安装X射线透视成像装置的C形臂，其中从旋转视点获取所述X射线透视图像序列中的图像，对 所述X射线透视图像序列中的图像基于ECG信号进入心脏周期的时间窗口，以及从所述2D透视图像序列构建所述动脉瘤的一个或多个三维（3D）血管造影图像体积。

公开(公告)号：US07379077B2

公开(公告)日：2008-05-27

申请号：US09818427

申请日：2001-03-27

Applicant: Ali Bani-Hashemi ,  Nassir Navab ,  Frank Sauer

Inventor： Ali Bani-Hashemi ,  Nassir Navab ,  Frank Sauer

IPC: G90G5/00 ,  G06T15/00

CPC classification number: B25J9/1689 ,  G05B2219/40121 ,  G05B2219/40126

Abstract: There is provided a method for augmented reality guided instrument positioning. A viewpoint is established, from which a line of sight to a point on a target defines a path for an instrument to follow during a positioning of the instrument to the point on the target. The instrument is aligned along the line of sight to the point on the target.

Abstract translation: 提供了一种增强现实引导仪器定位的方法。 建立一个观点，从目标到目标点的瞄准线定义了仪器在目标位置定位时跟随的路径。 仪器沿着视线对准目标点。

公开(公告)号：US07362920B2

公开(公告)日：2008-04-22

申请号：US10945675

申请日：2004-09-21

Applicant: Chenyang Xu ,  Xiaolei Huang ,  Yiyong Sun ,  Frank Sauer

Inventor： Chenyang Xu ,  Xiaolei Huang ,  Yiyong Sun ,  Frank Sauer

IPC: G06K9/32

CPC classification number: G06K9/6211 ,  G06K9/6212 ,  G06K2009/6213 ,  G06T7/246 ,  G06T7/277 ,  G06T7/337 ,  G06T7/35 ,  G06T2207/30016

Abstract: A method of aligning a pair of images includes providing a pair of images with a first image and a second image, wherein the images comprise a plurality of intensities corresponding to a domain of points in a D-dimensional space. Salient feature regions are identified in both the first image and the second image, a correspondence between each pair of salient feature regions is hypothesized, wherein a first region of each pair is on the first image and a second region of each pair is on the second image, the likelihood of the hypothesized correspondence of each pair of feature regions is measured, and a joint correspondence is determined from a set of pairs of feature regions with the greatest likelihood of correspondence.

Abstract translation: 对准一对图像的方法包括提供具有第一图像和第二图像的一对图像，其中图像包括对应于D维空间中的点的域的多个强度。 在第一图像和第二图像两者中识别出显着特征区域，假设每对突出特征区域之间的对应关系，其中每对的第一区域在第一图像上，并且每一对的第二区域位于第二图像的第二图像上 测量每对特征区域的假设对应关系的可能性，并且从一组对应关系最大的特征区域对确定联合对应关系。