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公开(公告)号：US06907095B1
公开(公告)日：2005-06-14
申请号：US09709203
申请日：2000-11-09
申请人： Fumio Nakano , Hitoshi Fujita
发明人： Fumio Nakano , Hitoshi Fujita
CPC分类号： H04L7/0012
摘要： A clock ride-over circuit in which clock ride-over may be achieved even if jitter is contained in clocks prior to and subsequent to ride-over and no control input signal for write and readout is applied from outside. A clock prior to rideover CLK—1 is detected by a clock subsequent to ride-over CLK—2 which is of a higher speed than the clock prior to ride-over. A timing signal TIM of a constant period, generated by a counter adapted for self-running with the clock prior to ride-over, is compared to the phase comparison signal COMP which is the result of the clock detection. Stable clock ride-over is possible by the phase comparison signal COMP having a pulse width larger than the jitter period of the clock subsequent to ride-over.
摘要翻译： 即使在骑乘之前和之后的时钟中包含抖动也可以实现时钟转换的时钟转换电路，并且不从外部施加用于写入和读出的控制输入信号。 Rideover之前的一个时钟CLK乘以一个比乘法之前的时钟更快的乘法器CLK-2之后的时钟来检测。 由适应于在乘坐之前的时钟自行运行的计数器产生的恒定周期的定时信号TIM与作为时钟检测结果的相位比较信号COMP进行比较。 可以通过相位比较信号COMP具有比乘坐后的时钟的抖动周期大的脉冲宽度的稳定的时钟跳变。
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公开(公告)号：US20090131439A1
公开(公告)日：2009-05-21
申请号：US11919135
申请日：2006-04-28
IPC分类号： A61K31/426 , A61K31/5377 , A61P11/00 , C07D417/10 , C07D277/38
CPC分类号： A61K31/56 , A61K9/10 , A61K31/5377 , C07D277/42
摘要： Disclosed is a method for the prevention and/or treatment of a chronic obstructive pulmonary disease by administrating a 5-membered cyclic compound represented by the formula below: or a pharmaceutically acceptable salt of the compound or a prodrug of the compound or salt: wherein X represents an oxygen or sulfur atom; R1 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; R2 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; Y1 represents single bond, a substituted or unsubstituted alkylene or the like; the wavy line means an (E) or (Z) coordination; R3 represents a hydrogen atom, a substituted or unsubstituted aryl or the like; Y2 represents a substituted or unsubstituted alkylene or an alkenylene; R4 represents a hydrogen atom, a substituted or unsubstituted alkanoyl or the like; and R5 represents a hydrogen atom or a substituted or unsubstituted alkyl.
摘要翻译： 本发明公开了一种预防和/或治疗慢性阻塞性肺疾病的方法，该方法是通过给予由下式表示的5元环状化合物：或化合物的药学上可接受的盐或其化合物或盐的前体药物：其中X 表示氧或硫原子; R1表示氢原子，取代或未取代的烷基等; R 2表示氢原子，取代或未取代的烷基等; Y1表示单键，取代或未取代的亚烷基等; 波浪线表示（E）或（Z）配位; R3表示氢原子，取代或未取代的芳基等; Y2表示取代或未取代的亚烷基或亚烯基; R4表示氢原子，取代或未取代的烷酰基等; 并且R 5表示氢原子或取代或未取代的烷基。
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公开(公告)号：US20050222226A1
公开(公告)日：2005-10-06
申请号：US11111845
申请日：2005-04-22
IPC分类号： A61P29/00 , A61P37/06 , A61P37/08 , C07D277/42 , C07D277/56 , C07D417/04 , C07D417/12 , C07D417/14 , C07D521/00 , A61K31/426 , C07D277/38
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/42 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14
摘要： A 5-membered cyclic compound of the formula: wherein X is oxygen or sulfur, R1 is hydrogen, substituted or unsubstituted alkyl, etc., R2 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, etc., Y1 is a direct bond, substituted or unsubstituted alkylene, —CO(CH2)n—, etc., the wavy line means (E)-configuration or (Z)-configuration, R3 is substituted or unsubstituted aryl, etc., Y2 is substituted or unsubstituted alkylene, etc., R4 is hydrogen, substituted or unsubstituted alkanoyl, substituted or unsubstituted alkyl, etc., R5 is hydrogen, etc., or a salt thereof, these compound being able to inhibit infiltration of leukocytes such as eosinophils and lymphocytes, by which being useful for the treatment of various kinds of inflammation.
摘要翻译： 下式的5元环状化合物：其中X是氧或硫，R 1是氢，取代或未取代的烷基等，R 2是氢，被取代的 或未取代的烷基，取代或未取代的芳基等，Y 1是直接键，取代或未取代的亚烷基，-CO（CH 2）n， （E）构型或（Z）构型，R 3是取代或未取代的芳基等。Y 2 - 是取代或未取代的亚烷基等，R 4是氢，取代或未取代的烷酰基，取代或未取代的烷基等，R 5是氢等，或 其盐，这些化合物能够抑制白细胞如嗜酸性粒细胞和淋巴细胞的浸润，由此可用于治疗各种炎症。
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公开(公告)号：US06458798B1
公开(公告)日：2002-10-01
申请号：US09763728
申请日：2001-02-27
申请人： Hitoshi Fujita , Fujio Antoku , Norio Fujiwara , Kiyotaka Iwai , Hiroshi Tanaka , Hajime Kawakami
发明人： Hitoshi Fujita , Fujio Antoku , Norio Fujiwara , Kiyotaka Iwai , Hiroshi Tanaka , Hajime Kawakami
IPC分类号： C07D23995
CPC分类号： C07D405/04 , C07D405/12 , C07D405/14
摘要： A pyrimidine derivative of the formula (1) or a salt thereof; has an inhibitory activity of production of Th2 type cytokines such as IL-4, IL-5, etc., and is useful as an therapeutic agent for allergic diseases, autoimmune diseases such as systemic lupus erythemathosus, etc., and acquired immunodeficiecy syndrome (AIDS) and so on.
摘要翻译： 式（1）的嘧啶衍生物或其盐具有产生Th2型细胞因子如IL-4，IL-5等的抑制活性，可用作过敏性疾病，自身免疫性疾病的治疗剂 如系统性红斑狼疮等，以及获得性免疫缺陷综合征（AIDS）等。
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公开(公告)号：US4975772A
公开(公告)日：1990-12-04
申请号：US346669
申请日：1989-05-03
申请人： Hitoshi Fujita
发明人： Hitoshi Fujita
CPC分类号： H04N5/217
摘要： The present invention relates to an image processing system for afterimage reduction for suitable use in a stereoscopic television apparatus. This system has been devised in consideration of the fact that the afterimage in a TV camera image to be displayed is most influenced by a frame image previous to the image to be displayed. The afterimage can be reduced by performing a novel algorism operation on each pixel value. Pixel values of a right image stored in a second input frame memory, which has been output from the TV camera prior to a left image to be displayed which is supplied from an input selector, is multiplied by a predetermined coefficient. The multiplied value is subtracted from pixel values of the left image to be displayed. Thus, a left image to be displayed, which has been subjected to afterimage reduction processing, is produced, and stored in a first output frame memory. Similarly, a right image to be displayed, which has been subjected to afterimage reduction processing, is produced.
摘要翻译： 本发明涉及一种用于立体电视设备中适用的余像减少的图像处理系统。 考虑到要显示的电视摄像机图像中的残像受到要显示的图像之前的帧图像的影响最大的事实，已经设计了该系统。 可以通过对每个像素值执行新颖的算法操作来减少残像。 将从输入选择器提供的要显示的左图像之前从TV摄像机输出的第二输入帧存储器中存储的右图像的像素值乘以预定系数。 从要显示的左图像的像素值中减去相乘值。 因此，产生已经进行了余像减少处理的待显示的左图像，并将其存储在第一输出帧存储器中。 类似地，产生已经进行了余像减少处理的要显示的右图像。
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公开(公告)号：US08012971B2
公开(公告)日：2011-09-06
申请号：US11919135
申请日：2006-04-28
IPC分类号： A61K31/426 , A61K31/5377 , C07D417/10 , C07D277/38
CPC分类号： A61K31/56 , A61K9/10 , A61K31/5377 , C07D277/42
摘要： Disclosed is a method for the prevention and/or treatment of a chronic obstructive pulmonary disease by administrating a 5-membered cyclic compound represented by the formula below: or a pharmaceutically acceptable salt of the compound or a prodrug of the compound or salt: wherein X represents an oxygen or sulfur atom; R1 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; R2 represents a hydrogen atom, a substituted or unsubstituted alkyl or the like; Y1 represents single bond, a substituted or unsubstituted alkylene or the like; the wavy line means an (E) or (Z) coordination; R3 represents a hydrogen atom, a substituted or unsubstituted aryl or the like; Y2 represents a substituted or unsubstituted alkylene or an alkenylene; R4 represents a hydrogen atom, a substituted or unsubstituted alkanoyl or the like; and R5 represents a hydrogen atom or a substituted or unsubstituted alkyl.
摘要翻译： 本发明公开了一种预防和/或治疗慢性阻塞性肺疾病的方法，该方法是通过给予由下式表示的5元环状化合物：或化合物的药学上可接受的盐或其化合物或盐的前体药物：其中X 表示氧或硫原子; R1表示氢原子，取代或未取代的烷基等; R 2表示氢原子，取代或未取代的烷基等; Y1表示单键，取代或未取代的亚烷基等; 波浪线表示（E）或（Z）配位; R3表示氢原子，取代或未取代的芳基等; Y2表示取代或未取代的亚烷基或亚烯基; R4表示氢原子，取代或未取代的烷酰基等; 并且R 5表示氢原子或取代或未取代的烷基。
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公开(公告)号：US20100256118A1
公开(公告)日：2010-10-07
申请号：US12793649
申请日：2010-06-03
申请人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
发明人： Yoshiaki ISOBE , Haruo Takaku , Haruhisa Ogita , Masanori Tobe , Ayumu Kurimoto , Tetsuhiro Ogino , Hitoshi Fujita
IPC分类号： A61K31/52 , C07D473/18 , A61K31/5377 , C07D473/24 , C07D473/16 , A61K31/55 , A61P11/06 , A61P17/00 , A61P37/02
CPC分类号： A61K31/5377 , A61K31/522 , A61K31/55
摘要： A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1): [wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
摘要翻译： 用作局部给药的药物，其作为抗过敏剂有效。 用于局部给药的药物含有作为活性成分的由通式（1）表示的腺嘌呤化合物：[其中环A表示6至10元，单或双环，芳族烃或5至10元，单或双环， 含有1至3个选自0至2个氮原子，0或1个氧原子和0或1个硫原子的杂原子的芳族杂环; n为0〜2的整数， m为0〜2的整数; R代表卤代，（取代）烷基等; X1代表氧，硫，NR1（R1代表氢或烷基）或单键; Y1表示单键，亚烷基等; Y2表示单键，亚烷基等; Z表示亚烷基; 并且Q1和Q2中的至少一个表示-COOR 10（其中R 10表示（un）取代的烷基等）等）或该化合物的药学上可接受的盐。
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公开(公告)号：US07396842B2
公开(公告)日：2008-07-08
申请号：US11111845
申请日：2005-04-22
IPC分类号： A61K31/44 , C07D417/00
CPC分类号： C07D231/12 , C07D233/56 , C07D249/08 , C07D277/42 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14
摘要： A 5-membered cyclic compound of the formula: wherein X is oxygen or sulfur, R1 is hydrogen, substituted or unsubstituted alkyl, etc., R2 is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, etc., Y1 is a direct bond, substituted or unsubstituted alkylene, —CO(CH2)n—, etc., the wavy line means (E)-configuration or (Z)-configuration, R3 is substituted or unsubstituted aryl, etc., Y2 is substituted or unsubstituted alkylene, etc., R4 is hydrogen, substituted or unsubstituted alkanoyl, substituted or unsubstituted alkyl, etc., R5 is hydrogen, etc., or a salt thereof, these compound being able to inhibit infiltration of leukocytes such as eosinophils and lymphocytes, by which being useful for the treatment of various kinds of inflammation.
摘要翻译： 下式的5元环状化合物：其中X是氧或硫，R 1是氢，取代或未取代的烷基等，R 2是氢，被取代的 或未取代的烷基，取代或未取代的芳基等，Y 1是直接键，取代或未取代的亚烷基，-CO（CH 2）n， （E）构型或（Z）构型，R 3是取代或未取代的芳基等。Y 2 - 是取代或未取代的亚烷基等，R 4是氢，取代或未取代的烷酰基，取代或未取代的烷基等，R 5是氢等，或 其盐，这些化合物能够抑制白细胞如嗜酸性粒细胞和淋巴细胞的浸润，由此可用于治疗各种炎症。
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公开(公告)号：US07080800B2
公开(公告)日：2006-07-25
申请号：US10298647
申请日：2002-11-19
申请人： Hiroaki Fujii , Koji Tanaka , Hitoshi Fujita , Koichi Furukawa
发明人： Hiroaki Fujii , Koji Tanaka , Hitoshi Fujita , Koichi Furukawa
IPC分类号： B65H75/48
CPC分类号： B60R22/44 , B60R2022/444 , B60R2022/4473
摘要： In controlling a seat belt retractor, at least one of signals selected from a state signal showing a movement of an occupant wearing a seat belt and an external signal obtained from detecting means installed in a vehicle during running thereof is received. Then, a rotational torque of a motor is selected to a predetermined reduction ratio corresponding to at least one of the state signal and the external signal from a plurality of torques. The motor is controlled to a predetermined torque, to thereby wind the webbing on the spool.
摘要翻译： 在控制座椅安全带卷收器时，接收从运行中安装在车辆中的检测装置获得的表示乘坐安全带的乘员的运动的状态信号和外部信号中选出的信号中的至少一种。 然后，根据多个转矩，将电动机的转矩选择为与至少一个状态信号和外部信号对应的预定减速比。 将电动机控制到预定的扭矩，从而将织带卷绕在卷轴上。
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公开(公告)号：US20060153011A1
公开(公告)日：2006-07-13
申请号：US10541725
申请日：2003-12-12
申请人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
发明人： Takashi Osa , Tomomi Murakami , Hitoshi Fujita
CPC分类号： G04C10/02
摘要： According to the present invention, in an electronic timepiece with a solar cell comprising a timepiece movement, a timepiece case for housing the timepiece movement, a casing ring for housing and holding the timepiece movement in the timepiece case, a solar cell and a dial, the solar cell is disposed almost vertically to a solar cell positioning portion provided in the casing ring, and the solar cell has a slender strip shape formed on a flexible substrate. Consequently, a solar cell need not be disposed in a timepiece movement, and it is only necessary to change a casing ring as an external component even when a panel cover diameter is changed, allowing a common use of a timepiece movement. Further, a solar cell can be coiled to match the size of a casing ring when it is incorporated in the casing ring, therefore a common solar cell can be used despite a change in the panel cover diameter of the timepiece.
摘要翻译： 根据本发明，在具有包括钟表运动的太阳能电池的电子钟表中，用于容纳钟表运动的钟表壳体，用于容纳并保持钟表壳体中的钟表运动的壳环，太阳能电池和表盘， 太阳能电池几乎垂直于设置在壳环中的太阳能电池定位部分，并且太阳能电池具有形成在柔性基板上的细长条形状。 因此，太阳能电池不需要设置在钟表运动中，即使当面板盖直径变化时，仅需要改变作为外部部件的外壳，从而允许通常使用时计运动。 此外，当太阳能电池被并入壳体环中时，可以将太阳能电池盘卷以匹配壳体环的尺寸，因此，尽管钟表的面板盖直径发生变化，但是可以使用普通的太阳能电池。
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