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公开(公告)号:US20130336885A1
公开(公告)日:2013-12-19
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/30 , G01N33/68 , A61K51/10 , A61K39/395
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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公开(公告)号:US09632091B2
公开(公告)日:2017-04-25
申请号:US14919388
申请日:2015-10-21
Applicant: Genentech, Inc.
Inventor: Siminder Atwal , Jo-Anne Hongo , Mark Lackner , Elizabeth Punnoose , Bonnee Rubinfeld , Rajesh Vij
IPC: G01N33/53 , G01N33/574 , C07K16/30 , C12N5/09
CPC classification number: G01N33/57434 , C07K16/3069 , C12N5/0693 , C12Y116/01 , C12Y301/03048 , G01N33/57492 , G01N2333/4742 , G01N2333/70596 , G01N2333/90287 , G01N2333/916 , G01N2800/52
Abstract: The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
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3.Anti-FcRH5 antibodies and immunoconjugates and methods of use 有权
Title translation: 抗FcRH5抗体和免疫缀合物及其使用方法公开(公告)号:US09017951B2
公开(公告)日:2015-04-28
申请号:US13673565
申请日:2012-11-09
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/53 , G01N33/574 , A61K39/395 , A61K45/06 , C07K16/28 , A61K31/69 , A61K39/00
CPC classification number: A61K39/3955 , A61K31/69 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K16/283 , C07K2317/24 , C07K2317/92 , A61K2300/00
Abstract: A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
Abstract translation: 提供了一种确定怀疑含有FcRH5的生物样品中FcRH5存在的方法,包括将生物样品暴露于分离的单克隆抗FcRH5抗体。
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4.Anti-FcRH5 antibodies and immunoconjugates and methods of use 有权
Title translation: 抗FcRH5抗体和免疫缀合物及其使用方法公开(公告)号:US08617559B2
公开(公告)日:2013-12-31
申请号:US13682581
申请日:2012-11-20
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US09360484B2
公开(公告)日:2016-06-07
申请号:US14078241
申请日:2013-11-12
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: C07K16/00 , G01N33/68 , A61K47/48 , C07K16/28 , G01N33/574 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/395 , A61K39/00
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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6.
公开(公告)号:US20130143237A1
公开(公告)日:2013-06-06
申请号:US13689407
申请日:2012-11-29
Applicant: Genentech, Inc.
Inventor: Siminder Atwal , Jo-Anne Hongo , Mark Lackner , Elizabeth Punnoose , Bonnee Rubinfeld , Rajesh Vij
CPC classification number: G01N33/57434 , C07K16/3069 , C12N5/0693 , C12Y116/01 , C12Y301/03048 , G01N33/57492 , G01N2333/4742 , G01N2333/70596 , G01N2333/90287 , G01N2333/916 , G01N2800/52
Abstract: The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
Abstract translation: 本发明提供诊断前列腺癌的方法。 本发明还提供新的抗STEAP-1抗体及其用途。
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公开(公告)号:US10435471B2
公开(公告)日:2019-10-08
申请号:US14313822
申请日:2014-06-24
Applicant: Genentech, Inc.
Inventor: Allen J. Ebens , Meredith C. Hazen , Jo-Anne Hongo , Jennifer W. Johnston , Teemu T. Junttila , Ji Li , Andrew G. Polson
IPC: C07K16/00 , C12P21/08 , C07K17/00 , A61K39/395 , A61K39/40 , C07K16/28 , A61K51/10 , A61K47/68 , C07K1/00 , A61K39/00
Abstract: The invention provides anti-FcRH5 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20180312579A1
公开(公告)日:2018-11-01
申请号:US15837647
申请日:2017-12-11
Applicant: Genentech, Inc,
Inventor: Elaine Storm , Frederic J. de Sauvage , Jeremy M. Murray , Cameron L. Noland , Yan Wu , Christine Tan , Jo-Anne Hongo , Yongmei Chen
CPC classification number: C07K16/18 , A61K39/3955 , A61K45/06 , A61K47/6843 , A61K2039/505 , C07K16/2818 , C07K16/3046 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: Provided herein are anti-RSPO antibodies, in particular anti-RSPO2 antibodies and/or anti-RSPO3 antibodies, and methods of using the same.
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公开(公告)号:US09175089B2
公开(公告)日:2015-11-03
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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10.ANTI-FcRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE 审中-公开
Title translation: ANTI-FcRH5抗体和免疫球蛋白及其使用方法公开(公告)号:US20140106374A1
公开(公告)日:2014-04-17
申请号:US14078241
申请日:2013-11-12
Applicant: Genentech, Inc.
Inventor: Kristi Elkins , Andrew Polson , Allen Ebens , Camelia Adams , Bing Zheng , Jagath R. Junutula , Jo-Anne Hongo , Yan Wu
IPC: G01N33/68
CPC classification number: G01N33/6854 , A61K31/138 , A61K31/4196 , A61K31/454 , A61K31/4745 , A61K31/517 , A61K31/56 , A61K31/568 , A61K31/5685 , A61K31/69 , A61K33/24 , A61K38/19 , A61K39/0011 , A61K39/39533 , A61K39/39558 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2803 , C07K16/283 , C07K2317/24 , C07K2317/522 , C07K2317/73 , G01N33/574 , G01N33/6857 , Y02A50/473
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物,以及使用这些物质组合物的方法。
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