-
公开(公告)号：US20240182476A1
公开(公告)日：2024-06-06
申请号：US18450646
申请日：2023-08-16
发明人： Masaaki Sawa , Mai Arai , Ryoko Nakai , Hirokazu Matsumoto , Catherine Pugh , Eric Hu , Juan Guerrero , Jesse Jacobsen , Jonathan William Medley , Jie Xu , Latesh Lad , Leena Patel , Michael Graupe , Qingming Zhu , Stephen Holmbo , Tetsuya Kobayashi , Will Watkins , Yasamin Moazami , Suet C. Yeung , Julian A. Codelli , Heath A. Weaver
IPC分类号： C07D487/04 , A61K31/395 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K31/553 , A61K31/695 , A61K31/704 , A61K31/7068 , A61K35/15 , A61K35/17 , A61K39/395 , A61K45/06 , C07D519/00 , C07F7/18
CPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K31/553 , A61K31/5545 , A61K31/695 , A61K31/704 , A61K31/7068 , A61K35/15 , A61K35/17 , A61K39/3955 , A61K45/06 , C07D519/00 , C07F7/1804
摘要： The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
-
公开(公告)号：US11845723B2
公开(公告)日：2023-12-19
申请号：US17127297
申请日：2020-12-18
发明人： Masaaki Sawa , Mai Arai , Ryoko Nakai , Hirokazu Matsumoto , Catherine Pugh , Eric Hu , Juan Guerrero , Jesse Jacobsen , Jonathan William Medley , Jie Xu , Latesh Lad , Leena Patel , Michael Graupe , Qingming Zhu , Stephen Holmbo , Tetsuya Kobayashi , Will Watkins , Yasamin Moazami , Suet C. Yeung , Julian A. Codelli , Heath A. Weaver
IPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , A61K31/538 , A61K31/55 , A61K31/553 , A61K31/704 , A61K31/7068 , C07D519/00 , A61K31/554 , A61K31/695 , A61K31/395 , A61K35/15 , A61K35/17 , A61K39/395 , A61K45/06 , C07F7/18
CPC分类号： C07D487/04 , A61K31/519 , A61K31/538 , A61K31/5377 , A61K31/55 , A61K31/553 , A61K31/5545 , A61K31/695 , A61K31/704 , A61K31/7068 , A61K35/15 , A61K35/17 , A61K39/3955 , A61K45/06 , C07D519/00 , C07F7/1804
摘要： The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
-
公开(公告)号：US20230116253A1
公开(公告)日：2023-04-13
申请号：US17844871
申请日：2022-06-21
发明人： Julian A. Codelli , Michael Graupe , Juan A. Guerrero , Jesse M. Jacobsen , Tetsuya Kobayashi , Jonathan William Medley , Yasamin Moazami , Leena B. Patel , Jie Xu , Suet C. Yeung
IPC分类号： C07D471/14
摘要： The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
-
公开(公告)号：US20230041518A1
公开(公告)日：2023-02-09
申请号：US17379175
申请日：2021-07-19
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
-
公开(公告)号：US11116760B2
公开(公告)日：2021-09-14
申请号：US16667306
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D413/14 , A61K31/5377 , A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D417/12 , C07D471/04 , C07D487/04
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
-
公开(公告)号：US12053462B2
公开(公告)日：2024-08-06
申请号：US17379175
申请日：2021-07-19
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D215/02 , A61K31/4375 , A61K31/47 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
CPC分类号： A61K31/47 , A61K31/4375 , A61K31/4709 , A61K31/501 , A61K31/506 , A61K31/517 , A61K31/519 , A61K31/5355 , A61K31/541 , A61K45/06 , C07D215/14 , C07D401/10 , C07D401/12 , C07D401/14 , C07D405/14 , C07D407/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D487/04 , C07D215/18 , C07D401/04 , C07D413/04 , C07D417/14 , C07D475/02 , C07D491/04 , C07D491/06 , C07D491/08 , C07D498/10 , C07D513/04
摘要： The present disclosure provides a compound of Formula (I):
or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.-
公开(公告)号：US11174256B2
公开(公告)日：2021-11-16
申请号：US16667532
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04 , A61K31/437 , A61K31/541
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
-
公开(公告)号：US20210053967A1
公开(公告)日：2021-02-25
申请号：US16991708
申请日：2020-08-12
发明人： Peter A. Blomgren , Taryn L. Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole A. Nava , Leena Patel , Jason K. Perry , Natalie Seeger , Kirk L. Stevens , Zhongdong Zhao
IPC分类号： C07D471/04 , C07D213/64 , C07D413/12 , C07D491/052 , C07C233/87 , C07D239/54 , C07D239/96 , C07D215/227 , C07D413/14
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), therapeutic methods for treating inflammatory disease.
-
公开(公告)号：US20200165248A1
公开(公告)日：2020-05-28
申请号：US16667532
申请日：2019-10-29
发明人： Peter A. Blomgren , Taryn Campbell , Jayaraman Chandrasekhar , Christopher T. Clark , Julian A. Codelli , Kevin S. Currie , Jeffrey E. Kropf , Yasamin Moazami , Nicole Nava , Leena Patel , Stephane Perreault , Jason K. Perry , Kassandra F. Sedillo , Natalie Seeger , Kirk L. Stevens , Jennifer Anne Treiberg , Suet C. Yeung , Zhongdong Zhao
IPC分类号： C07D471/04 , A61K31/541
摘要： The present disclosure provides a compound of Formula (I): or a pharmaceutically acceptable salt thereof as described herein. The present disclosure also provides pharmaceutical compositions comprising a compound of Formula (I), processes for preparing compounds of Formula (I), and therapeutic methods for treating inflammatory disease.
-
公开(公告)号：US11976072B2
公开(公告)日：2024-05-07
申请号：US17845534
申请日：2022-06-21
发明人： Julian A. Codelli , Michael Graupe , Juan A. Guerrero , Stephen D. Holmbo , Tetsuya Kobayashi , Yasamin Moazami , Leena B. Patel , Heath A. Weaver , Jie Xu , Suet C. Yeung , QingMing Zhu
IPC分类号： C07D487/04 , A61P31/18 , A61P31/20 , A61P35/00 , A61P35/04 , C07D519/00
CPC分类号： C07D487/04 , C07D519/00
摘要： The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
-
-
-
-
-
-
-
-
-
搜索结果
29 条记录 (耗时 0.046 秒)
