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公开(公告)号：US10415069B2
公开(公告)日：2019-09-17
申请号：US15700978
申请日：2017-09-11
申请人： Glycosyn LLC
IPC分类号： C12P19/02 , C07H5/06 , C07H13/04 , C07H1/00 , C12N9/10 , C12P19/18 , C12P19/04 , C07K14/245 , C12N15/52 , C12P19/16 , C12P19/26
摘要： The invention provides compositions and methods for engineering bacteria to produce sialylated and N-acetylglucosamine-containing oligosaccharides, and the use thereof in the prevention or treatment of infection.
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2.发明授权公开(公告)号：US10286001B2
公开(公告)日：2019-05-14
申请号：US15419241
申请日：2017-01-30
摘要： The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
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3.发明授权公开(公告)号：US10273516B2
公开(公告)日：2019-04-30
申请号：US14708568
申请日：2015-05-11
申请人： Glycosyn LLC
摘要： The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
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公开(公告)号：US09970018B2
公开(公告)日：2018-05-15
申请号：US15712074
申请日：2017-09-21
申请人： Glycosyn LLC
IPC分类号： C12P19/18 , C12N15/70 , C12P19/26 , C12P19/00 , C07H13/04 , C07H3/06 , C12N9/38 , C12N9/10 , C12N9/00
CPC分类号： C12N15/70 , C07H3/06 , C07H13/04 , C12N9/00 , C12N9/1051 , C12N9/2471 , C12P19/00 , C12P19/18 , C12P19/26 , Y02P20/52
摘要： The invention provides compositions and methods for engineering bacteria to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
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5.发明申请公开(公告)号：US20170306373A1
公开(公告)日：2017-10-26
申请号：US15509820
申请日：2015-09-09
申请人： Glycosyn LLC
CPC分类号： C12P19/18 , C07H3/06 , C07H5/06 , C12N9/1051 , C12P19/26 , C12Y204/01065
摘要： The invention relates to methods and compositions for the production of fucosylated oligosaccharides.
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6.发明申请公开(公告)号：US20170081353A1
公开(公告)日：2017-03-23
申请号：US15307914
申请日：2015-05-14
申请人： Glycosyn LLC
CPC分类号： C07H13/04 , C12N9/1051 , C12N15/70 , C12P19/00 , C12P19/04 , C12P19/18 , C12Y204/01069
摘要： The invention provides compositions and methods for engineering E. coli or other host production bacterial strains to produce fucosylated oligosaccharides, and the use thereof in the prevention or treatment of infection.
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公开(公告)号：US11324766B2
公开(公告)日：2022-05-10
申请号：US17320003
申请日：2021-05-13
申请人： Glycosyn LLC
IPC分类号： A61K31/702 , A61K9/00 , A61K45/06 , A61K35/745 , A61K35/742 , A61K35/74 , A23L33/125 , A23L33/00 , A23L2/52 , A61K35/747
摘要： The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection-induced host inflammation and/or to promote recovery from a respiratory pathogen infection-induced host inflammation in a subject.
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公开(公告)号：US11274325B2
公开(公告)日：2022-03-15
申请号：US16221193
申请日：2018-12-14
申请人： Glycosyn LLC
摘要： Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
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9.发明申请公开(公告)号：US20190255083A1
公开(公告)日：2019-08-22
申请号：US16403095
申请日：2019-05-03
摘要： The invention provides compositions and methods for utilizing synthetic human milk oligosaccharides as prebiotics.
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公开(公告)号：US20190218582A1
公开(公告)日：2019-07-18
申请号：US16221193
申请日：2018-12-14
申请人： Glycosyn LLC
IPC分类号： C12P19/02 , C12N9/10 , C07K14/245 , C12N9/38 , C12N9/12
CPC分类号： C12P19/02 , C07K14/245 , C12N9/1051 , C12N9/1081 , C12N9/1085 , C12N9/1241 , C12N9/2471 , C12Y204/01065 , C12Y204/01149 , C12Y204/99007 , C12Y205/01056 , C12Y207/07043 , C12Y302/01023 , C12Y302/01183
摘要： Provided herein, inter alia, are methods, bacteria, nucleic acids, and polypeptides for producing sialylated oligosaccharides.
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