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    Two-Stage Delivery Systems and Methods for Fixing a Leadless Implant to Tissue
    1.
    发明申请
    Two-Stage Delivery Systems and Methods for Fixing a Leadless Implant to Tissue 审中-公开
    将无铅植入物固定到组织的两阶段递送系统和方法

    公开(公告)号：US20110270340A1

    公开(公告)日：2011-11-03

    申请号：US12771037

    申请日：2010-04-30

    申请人： Gianfranco Pellegrini ,  Susan Rea Peterson ,  Travis Rowe ,  Arvind Srinivas ,  Scott Doig ,  Barry Wohl

    发明人： Gianfranco Pellegrini ,  Susan Rea Peterson ,  Travis Rowe ,  Arvind Srinivas ,  Scott Doig ,  Barry Wohl

    IPC分类号： A61N1/05

    CPC分类号： A61N1/3756 ,  A61N1/0573 ,  A61N1/37205 ,  A61N1/37518

    摘要： Systems and methods of delivering and retaining a leadless medical implant to tissue, wherein a docking base and the implant are sequentially delivered to an implantation site. In a first stage, the docking base is delivered and deployed into tissue at an implantation site. In a second stage, the implant is navigated through the vasculature and coupled to the docking base. Various mechanisms for navigating the implant to the previously implanted docking base and coupling the implant thereto are described. Navigational mechanisms include advancing the implant over a proximally extending wire portion that is releasably attached to the previously implanted docking base, utilizing fluoroscopic visualization to guide the implant to a previously implanted docking base that is at least partially radiopaque and utilizing electromagnetism to guide the implant to a previously implanted docking base that is electro-magnetizable.

    摘要翻译： 将无引导医用植入物递送和保持到组织的系统和方法，其中对接基座和植入物被顺序地递送到植入部位。 在第一阶段，对接基座在植入部位被传送并部署到组织中。 在第二阶段，植入物通过脉管系统导航并且连接到对接基座。 描述了用于将植入物导航到先前植入的对接底座并将植入物联接到其上的各种机构。 导航机构包括将植入物推进在可释放地附接到先前植入的对接基座的近端延伸的线部分上，利用荧光透视可视化将植入物引导至至少部分不透射线的先前植入的对接基座，并利用电磁力将植入物导向 先前植入的可电磁化的对接基座。

    Method of Using Catheter with Rotating Portion
    3.
    发明申请
    Method of Using Catheter with Rotating Portion 有权
    使用导管与旋转部分的方法

    公开(公告)号：US20110245782A1

    公开(公告)日：2011-10-06

    申请号：US12754827

    申请日：2010-04-06

    申请人： William Berthiaume ,  Gianfranco Pellegrini ,  Scott Doig

    发明人： William Berthiaume ,  Gianfranco Pellegrini ,  Scott Doig

    IPC分类号： A61M25/01 ,  A61L29/14

    CPC分类号： A61M25/01 ,  A61M25/0152

    摘要： A catheter includes a proximal portion and a distal portion, the distal portion including an arcuate portion. The catheter further includes a rotating portion, the rotating portion connecting the proximal portion and distal portion, the rotating portion including a first piece and a second piece, wherein the first piece and second piece create a snap fit. Methods of using the catheter include threading the inserted catheter through the vasculature and allowing the distal portion to freely rotate about an axis defined by the rotating portion responsive to any tortuosity in the vasculature.

    摘要翻译： 导管包括近端部分和远端部分，远侧部分包括弓形部分。 导管还包括旋转部分，旋转部分连接近端部分和远端部分，旋转部分包括第一部分和第二部分，其中第一部分和第二部分形成卡扣配合。 使用导管的方法包括穿过脉管系统插入插入的导管，并允许远端部分响应于脉管系统中的任何曲折度而围绕由旋转部分限定的轴线自由旋转。

    Method of using catheter with rotating portion
    4.
    发明授权
    Method of using catheter with rotating portion 有权
    使用具有旋转部分的导管的方法

    公开(公告)号：US09421343B2

    公开(公告)日：2016-08-23

    申请号：US12754827

    申请日：2010-04-06

    申请人： William Berthiaume ,  Gianfranco Pellegrini ,  Scott Doig

    发明人： William Berthiaume ,  Gianfranco Pellegrini ,  Scott Doig

    IPC分类号： A61M25/01

    CPC分类号： A61M25/01 ,  A61M25/0152

    摘要： A catheter includes a proximal portion and a distal portion, the distal portion including an arcuate portion. The catheter further includes a rotating portion, the rotating portion connecting the proximal portion and distal portion, the rotating portion including a first piece and a second piece, wherein the first piece and second piece create a snap fit. Methods of using the catheter include threading the inserted catheter through the vasculature and allowing the distal portion to freely rotate about an axis defined by the rotating portion responsive to any tortuosity in the vasculature.

    摘要翻译： 导管包括近端部分和远端部分，远侧部分包括弓形部分。 导管还包括旋转部分，旋转部分连接近端部分和远端部分，旋转部分包括第一部分和第二部分，其中第一部分和第二部分形成卡扣配合。 使用导管的方法包括穿过脉管系统插入插入的导管，并允许远端部分响应于脉管系统中的任何曲折度而围绕由旋转部分限定的轴线自由旋转。

    Stents for prosthetic heart valves
    6.
    发明授权
    Stents for prosthetic heart valves 有权
    假体心脏瓣膜支架

    公开(公告)号：US08623079B2

    公开(公告)日：2014-01-07

    申请号：US13093305

    申请日：2011-04-25

    申请人： Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

    发明人： Padraig Savage ,  Gianfranco Pellegrini ,  Finn Rinne ,  Matthew Rust ,  Michael Krivoruchko

    IPC分类号： A61F2/24

    CPC分类号： A61F2/24 ,  A61F2/2418 ,  A61F2/848 ,  A61F2002/8483 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/008

    摘要： A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

    摘要翻译： 一种支架式阀，包括具有大致管状主体部分，内部区域，纵向轴线，第一端部，第二端部和外部表面的支架结构; 至少一个流出倒钩，其从所述支架的外表面邻近所述支架结构的所述第一端延伸并朝向所述支架结构的第二端; 至少一个流入倒钩，其从所述支架的外表面延伸到所述支架结构的第二端并朝向所述支架结构的第一端; 以及附接在支架结构的内部区域内的阀结构。

    HEATING DEVICE WITH IRREVERSIBLE THERMODYNAMIC CYCLE FOR HEATING INSTALLATIONS HAVING HIGH DELIVERY TEMPERATURE
    7.
    发明申请
    HEATING DEVICE WITH IRREVERSIBLE THERMODYNAMIC CYCLE FOR HEATING INSTALLATIONS HAVING HIGH DELIVERY TEMPERATURE 审中-公开
    具有不可逆温度循环的加热装置，用于加热具有高输送温度的安装

    公开(公告)号：US20120198878A1

    公开(公告)日：2012-08-09

    申请号：US13501505

    申请日：2010-10-13

    申请人： Gianfranco Pellegrini

    发明人： Gianfranco Pellegrini

    IPC分类号： F25B29/00

    CPC分类号： F25B30/02 ,  F25B7/00 ,  F25B40/02 ,  F25B2339/047

    摘要： The present invention relates to a heating device with irreversible thermodynamic cycle. The device comprises a low temperature circuit and a high temperature circuit in which respectively a first and a second operating fluid circulate. Each circuit comprises evaporating, compression, condensation and expansion means of the respective operating fluid. The low temperature circuit absorbs thermal energy from a supply water flow for evaporating the first operating fluid. The thermal energy deriving from the condensation of the first operating fluid is used for evaporating the second fluid. Instead, the thermal energy deriving from the condensation of the second fluid is used for heating a delivery water flow. According to the invention, the two operating circuits each comprise cooling means interposed between the corresponding condensation and expansion means. Such cooling means are in thermal contact with independent partial flows of the supply water flow so as to heat the latter overall by means of thermal energy removed from the operating fluids circulating in the two circuits.

    摘要翻译： 本发明涉及一种具有不可逆热循环的加热装置。 该装置包括低温电路和高温电路，其中第一和第二工作流体分别循环。 每个回路包括各个工作流体的蒸发，压缩，冷凝和膨胀装置。 低温回路从供水流中吸收热能以蒸发第一工作流体。 来自第一工作流体的冷凝的热能用于蒸发第二流体。 相反，来自第二流体的冷凝的热能用于加热输送水流。 根据本发明，两个操作电路各自包括插入在相应的冷凝和膨胀装置之间的冷却装置。 这种冷却装置与供水流的独立部分流动热接触，以便通过从在两个回路中循环的工作流体移除的热能来加热后者。

    Stent With Improved Mechanical Properties
    8.
    发明申请
    Stent With Improved Mechanical Properties 审中-公开
    具有改善机械性能的支架

    公开(公告)号：US20080319534A1

    公开(公告)日：2008-12-25

    申请号：US11767308

    申请日：2007-06-22

    申请人： Matthew J. Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

    发明人： Matthew J. Birdsall ,  Gianfranco Pellegrini ,  Justin Goshgarian ,  Jeffrey Allen

    IPC分类号： A61F2/06

    CPC分类号： A61F2/88 ,  A61F2/915 ,  A61F2002/91508 ,  A61F2002/91558 ,  A61F2220/0058 ,  A61F2250/0036

    摘要： A stent includes a central portion having a first waveform. The first waveform is wrapped around a longitudinal axis of the stent at a pitch to define a plurality of helical turns. The stent also includes an end segment connected to one end of the central portion. The end segment has a second waveform that includes a plurality of struts and a plurality of crowns. Each of the plurality of struts has a different length so that peaks of the crowns that define an end of the stent lie within a plane that is substantially perpendicular to the longitudinal axis. Cross-sectional areas of the struts having different lengths vary so that the struts move substantially uniformly during radial contraction and/or radial expansion of the stent.

    摘要翻译： 支架包括具有第一波形的中心部分。 第一波形以间距缠绕在支架的纵向轴线上以限定多个螺旋形匝。 支架还包括连接到中心部分的一端的端部段。 端部段具有包括多个支柱和多个冠部的第二波形。 多个支柱中的每一个具有不同的长度，使得限定支架的端部的冠部的顶点位于基本上垂直于纵向轴线的平面内。 具有不同长度的支柱的横截面积变化，使得支柱在支架的径向收缩和/或径向膨胀期间基本均匀地移动。

    Concurrent read/write architecture for a flash memory
    9.
    发明授权
    Concurrent read/write architecture for a flash memory 失效
    Flash存储器的并发读/写架构

    公开(公告)号：US5894437A

    公开(公告)日：1999-04-13

    申请号：US12268

    申请日：1998-01-23

    申请人： Gianfranco Pellegrini

    发明人： Gianfranco Pellegrini

    IPC分类号： G11C7/18 ,  G11C16/08 ,  G11C16/04

    CPC分类号： G11C16/08 ,  G11C7/18 ,  G11C2216/22

    摘要： A semiconductor device having an array of flash memory cells and for each column of cells, a global read bit line, a global write bit line, and a plurality of local bit lines, wherein the column of cells is divided into a plurality of subcolumns and each local bit line is electrically coupled to each of the cells in a subcolumn associated with the local bit line. The local bit line is coupled and decoupled to the global read bit line by a local read select transistor and is coupled and decoupled to the global write bit line by a local write select transistor. By coupling one local bit line for a column to the global read bit line and coupling another local bit line to the global write bit line, one cell can be written while another cell is read from, even though the cell being read and the cell being written are in the same column. A variation uses the two global bit lines as read lines or read/write lines instead of a global read bit line and a global write bit line for each column.

    摘要翻译： 一种半导体器件，具有闪存单元阵列和每列单元阵列，全局读位线，全局写位线和多个局部位线，其中该列单元被分成多个子列和 每个本地位线电耦合到与局部位线相关联的子列中的每个单元。 局部位线由本地读选晶体管耦合并去耦到全局读位线，并通过局部写选择晶体管与全局写位线耦合并去耦合。 通过将列的一个局部位线耦合到全局读位线并将另一局部位线耦合到全局写位线，即使读取单元并且单元为 写在同一列。 变体使用两条全局位线作为读线或读/写线，而不是每列的全局读位线和全局写位线。