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公开(公告)号：US11377440B2
公开(公告)日：2022-07-05
申请号：US16652221
申请日：2018-10-04
Inventor： David T. Fosbenner , Todd L. Graybill , Jianxing Kang , Bryan W. King , Yunfeng Lan , Lara Kathryn Leister , Mukesh K. Mahajan , John F. Mehlmann , Angel I. Morales-Ramos , George Scott Pesiridis , Joshi M. Ramanjulu , Joseph J. Romano , Stuart Paul Romeril , Mark J. Schulz , Huiqiang Zhou , Junya Qu
IPC: C07D403/14 , C07D401/14 , C07D405/14
Abstract: Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
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公开(公告)号：US10220030B2
公开(公告)日：2019-03-05
申请号：US15811712
申请日：2017-11-14
Inventor： Michael Jonathan Bury , Linda N. Casillas , Adam Kenneth Charnley , Pamela A. Haile , Robert W. Marquis, Jr. , John F. Mehlmann , Joseph J. Romano , Robert R. Singhaus, Jr. , Gren Z. Wang
IPC: A61K31/4709 , C07D401/12 , C07D405/14 , C07D417/12 , C07D215/44 , C07D405/12 , C07D417/14 , C07D471/04 , A61K31/4706
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.
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公开(公告)号：US09650364B2
公开(公告)日：2017-05-16
申请号：US14762905
申请日：2014-02-19
Inventor： Linda N. Casillas , Adam Kenneth Charnley , Xiaoyang Dong , Pamela A. Haile , Michael P. Demartino , John F. Mehlmann
IPC: C07D403/12 , C07D405/14 , A61K9/20 , A61K9/48
CPC classification number: C07D403/12 , A61K9/2054 , A61K9/4866 , C07D405/14
Abstract: Disclosed are compounds that are inhibitors of RIP2 kinase and methods of making and using the same.
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公开(公告)号：US20150094333A1
公开(公告)日：2015-04-02
申请号：US14396559
申请日：2013-09-13
Inventor： Linda N. Casillas , Michael P. Demartino , Pamela A. Haile , John F. Mehlmann , Joshi M. Ramanjulu , Robert Singhaus, JR.
IPC: C07D401/12
CPC classification number: C07D401/12
Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
Abstract translation: 公开了具有下式的化合物：其中R1，R2R3，R4和R5如本文所定义，以及制备和使用它们的方法。
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Patent Agency Ranking
公开(公告)号：US20160060249A1
公开(公告)日：2016-03-03
申请号：US14933201
申请日：2015-11-05
Inventor： Linda N. CASILLAS , Adam Kenneth Charnley , Pamela A. Haile , Terry Vincent Hughes , Robert W. Marquis, JR. , John F. Mehlmann , Michael Reilly , Joseph J. Romano , Robert R. Singhaus, JR.
IPC: C07D401/12 , C07D405/14
CPC classification number: C07D401/12 , C07D405/14
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
Abstract translation: 公开了具有下式的化合物：其中R1，R2，R3，R4和R5如本文所定义，以及制备和使用它们的方法。
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公开(公告)号：US20140256949A1
公开(公告)日：2014-09-11
申请号：US14283352
申请日：2014-05-21
Inventor： Linda N. CASILLAS , Adam Kenneth Charnley , Pamela A. Haile , Terry Vincent Hughes , Robert W. Marquis, JR. , John F. Mehlmann , Michael Reilly , Joseph J. Romano , Robert R. Singhaus, JR.
IPC: C07D405/14 , C07D401/12
CPC classification number: C07D401/12 , C07D405/14
Abstract: Disclosed are compounds having the formula: wherein R1, R2, R3, R4 and R5 are as defined herein, and methods of making and using the same.
Abstract translation: 公开了具有下式的化合物：其中R1，R2，R3，R4和R5如本文所定义，以及制备和使用它们的方法。
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公开(公告)号：US11970480B2
公开(公告)日：2024-04-30
申请号：US17663749
申请日：2022-05-17
Inventor： Adam Kenneth Charnley , Michael G. Darcy , Jason W. Dodson , Xiaoyang Dong , Terry V. Hughes , Jianxing Kang , Lara Kathryn Leister , Yiqian Lian , Yue Li , John F. Mehlmann , Neysa Nevins , Joshi M. Ramanjulu , Joseph J. Romano , Gren Z. Wang , Guosen Ye , Daohua Zhang
IPC: C07D403/14 , C07D405/14 , C07D413/14 , C07D487/22 , C07D493/10 , C07D498/18 , C07F9/6558
CPC classification number: C07D403/14 , C07D405/14 , C07D413/14 , C07D487/22 , C07D493/10 , C07D498/18 , C07F9/65583
Abstract: Disclosed are compounds having the formula:
wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.-
公开(公告)号：US10189820B2
公开(公告)日：2019-01-29
申请号：US15730664
申请日：2018-01-03
Inventor： John F. Mehlmann , Joseph J. Romano
IPC: A61K31/5355 , C07D403/14 , C07D405/14 , C07D413/14 , C07D487/22 , C07D493/10 , C07D498/18 , C07F9/6558
Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.
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公开(公告)号：US09216965B2
公开(公告)日：2015-12-22
申请号：US14396559
申请日：2013-09-13
Inventor： Linda N. Casillas , Michael P. Demartino , Pamela A. Haile , John F. Mehlmann , Joshi M. Ramanjulu , Robert Singhaus, Jr.
IPC: C07D401/12
CPC classification number: C07D401/12
Abstract: Disclosed are compounds having the formula: wherein R1, R2R3, R4 and R5 are as defined herein, and methods of making and using the same.
Abstract translation: 公开了具有下式的化合物：其中R1，R2R3，R4和R5如本文所定义，以及制备和使用它们的方法。
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