公开(公告)号：US09346547B2

公开(公告)日：2016-05-24

申请号：US13975590

申请日：2013-08-26

Applicant: Google Inc.

Inventor： William Graham Patrick ,  James Ryan Burgess ,  Andrew Conrad

IPC: B64D1/12 ,  B64C39/02 ,  B64D1/22

CPC classification number: B64D1/12 ,  B64C39/024 ,  B64C2201/128 ,  B64C2201/141 ,  B64C2201/145 ,  B64D1/22

Abstract: Embodiments described herein may help to provide medical support via a fleet of unmanned aerial vehicles (UAVs). An illustrative UAV may include a housing, a payload, a line-deployment mechanism coupled to the housing and a line, and a payload-release mechanism that couples the line to the payload, wherein the payload-release mechanism is configured to release the payload from the line. The UAV may further include a control system configured to determine that the UAV is located at or near a delivery location and responsively: operate the line-deployment mechanism according to a variable deployment-rate profile to lower the payload to or near to the ground, determine that the payload is touching or is within a threshold distance from the ground, and responsively operate the payload-release mechanism to release the payload from the line.

Abstract translation: 本文描述的实施例可以帮助经由无人机（UAV）的车队提供医疗支持。 说明性的UAV可以包括外壳，有效载荷，耦合到外壳和线路的线路部署机构，以及将线路耦合到有效载荷的有效载荷释放机构，其中所述有效载荷释放机构被配置为释放所述有效载荷 从线上 UAV还可以包括被配置为确定UAV位于交付位置处或附近的响应的控制系统：根据可变部署速率简档操作线路部署机构以将有效载荷降低到地面或靠近地面， 确定有效载荷正在接触或处于距离地面的阈值距离内，并且响应地操作有效负载释放机构以从线路释放有效载荷。

公开(公告)号：US20140377731A1

公开(公告)日：2014-12-25

申请号：US13924246

申请日：2013-06-21

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters

IPC: G09B23/30

CPC classification number: G09B23/303

Abstract: A test model has an outer polymer layer that models an exterior surface of a human arm and includes at least a wrist portion, an inner polymer core that is at least partially surrounded by the outer polymer layer and extends into the wrist portion, and polymer tubing adjacent to the inner polymer core. The polymer tubing is at least partially surrounded by the outer polymer layer and extends into the wrist portion. The polymer tubing has a first fluid inlet and a first fluid outlet. The test model is substantially free of metallic and magnetic materials.

Abstract translation: 测试模型具有外部聚合物层，其对人类臂的外表面进行建模，并且至少包括手腕部分，至少部分地被外部聚合物层包围并延伸到腕部的内部聚合物芯，以及聚合物管 邻近内聚合物芯。 聚合物管至少部分地被外聚合物层包围并延伸到腕部。 聚合物管道具有第一流体入口和第一流体出口。 测试模型基本上不含金属和磁性材料。

公开(公告)号：US20150158587A1

公开(公告)日：2015-06-11

申请号：US13975590

申请日：2013-08-26

Applicant: Google Inc.

Inventor： William Graham Patrick ,  James Ryan Burgess ,  Andrew Conrad

IPC: B64D1/12 ,  B64C39/02

CPC classification number: B64D1/12 ,  B64C39/024 ,  B64C2201/128 ,  B64C2201/141 ,  B64C2201/145 ,  B64D1/22

Abstract: Embodiments described herein may help to provide medical support via a fleet of unmanned aerial vehicles (UAVs). An illustrative UAV may include a housing, a payload, a line-deployment mechanism coupled to the housing and a line, and a payload-release mechanism that couples the line to the payload, wherein the payload-release mechanism is configured to release the payload from the line. The UAV may further include a control system configured to determine that the UAV is located at or near a delivery location and responsively: operate the line-deployment mechanism according to a variable deployment-rate profile to lower the payload to or near to the ground, determine that the payload is touching or is within a threshold distance from the ground, and responsively operate the payload-release mechanism to release the payload from the line.

Abstract translation: 本文描述的实施例可以帮助经由无人机（UAV）的车队提供医疗支持。 说明性的UAV可以包括外壳，有效载荷，耦合到外壳和线路的线路部署机构，以及将线路耦合到有效载荷的有效载荷释放机构，其中所述有效载荷释放机构被配置为释放所述有效载荷 从线上 UAV还可以包括被配置为确定UAV位于交付位置处或附近的响应的控制系统：根据可变部署速率简档操作线路部署机构以将有效载荷降低到地面或靠近地面， 确定有效载荷正在接触或处于距离地面的阈值距离内，并且响应地操作有效负载释放机构以从线路释放有效载荷。

公开(公告)号：US20140378777A1

公开(公告)日：2014-12-25

申请号：US13924296

申请日：2013-06-21

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters

IPC: A61B5/1455 ,  A61B5/05 ,  A61B5/00 ,  A61B5/055

CPC classification number: A61B5/14503 ,  A61B5/0022 ,  A61B5/02055 ,  A61B5/0515 ,  A61B5/055 ,  A61B5/1112 ,  A61B5/1455 ,  A61B5/1459 ,  A61B5/4848 ,  A61B5/681 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455 ,  A61N2/002 ,  G06F19/00 ,  G06F19/3456 ,  G16H40/63

Abstract: A method for real-time, high-density physiological data collection includes automatically measuring, by a wearable device, one or more physiological parameters during each of a plurality of measurement periods, and upon conclusion of a measurement period, for each of the plurality of measurement periods, automatically transmitting by the wearable device data representative of the physiological parameters measured during that measurement period, to a server, the server configured to develop a baseline profile based on the data transmitted by the wearable device for the plurality of measurement periods. The measurement periods may extend through a plurality of consecutive days, and each of the consecutive days may include multiple measurement periods. At least some of the physiological parameters are measured by non-invasively detecting one or more analytes in blood circulating in subsurface vasculature proximate to the wearable device.

Abstract translation: 一种用于实时，高密度生理数据收集的方法，包括通过可穿戴设备在多个测量周期的每一个期间自动测量一个或多个生理参数，并且在测量周期结束时，针对多个 测量周期，由可穿戴设备自动发送表示在该测量期间测量的生理参数的数据到服务器，服务器被配置为基于由可穿戴设备在多个测量周期中发送的数据来开发基线简档。 测量周期可以延续多个连续的天，并且连续的每一天可以包括多个测量周期。 至少一些生理参数通过非侵入性地检测在靠近可穿戴装置的地下脉管系统中循环的血液中的一种或多种分析物来测量。

公开(公告)号：US20150112168A1

公开(公告)日：2015-04-23

申请号：US14061334

申请日：2013-10-23

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters ,  Vikram Singh Bajaj ,  Jason Thompson ,  Mark Askew

IPC: A61B5/05

CPC classification number: A61B5/14546 ,  A61B5/0022 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/021 ,  A61B5/024 ,  A61B5/05 ,  A61B5/0515 ,  A61B5/055 ,  A61B5/1455 ,  A61B5/681 ,  A61B5/7228 ,  G01R33/24 ,  G01R33/44 ,  G06F19/00 ,  G16H40/63

Abstract: A method for modulating a response signal includes introducing functionalized magnetic particles configured to interact with target analytes into the body, applying a magnetic field sufficient to draw the functionalized magnetic particles towards a surface of the lumen of subsurface vasculature closest to an internally or externally applied mask having a spatial arrangement, and detecting a response signal, which includes a background signal and an analyte response signal, transmitted from the subsurface vasculature. The analyte response signal related to interaction of the functionalized magnetic particles with the target analytes and is modulated with respect to the background signal due, at least in part, to the spatial arrangement of the mask. The target analytes may be non-invasively detected by differentiating the analyte response signal from the background signal due, at least in part, to the modulation of the analyte response signal.

Abstract translation: 用于调节响应信号的方法包括引入配置成与目标分析物相互作用的功能化磁性颗粒进入体内，施加足以将官能化的磁性颗粒吸引到最靠近内部或外部施加的掩模的地下脉管系统的内腔表面的磁场 具有空间布置，并且检测包括从地下脉管系统发送的背景信号和分析物响应信号的响应信号。 分析物响应信号与功能化磁性颗粒与目标分析物的相互作用相关，并且相对于背景信号被调制，至少部分地由于掩模的空间排列。 目标分析物可以通过区分来自背景信号的分析物响应信号而被非侵入性地检测，至少部分地由于分析物响应信号的调制。

公开(公告)号：US20150110721A1

公开(公告)日：2015-04-23

申请号：US14061251

申请日：2013-10-23

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters ,  Vikram Singh Bajaj ,  Jason Thompson ,  Mark Askew

IPC: A61B5/145 ,  A61B5/00 ,  A61B5/05 ,  A61K49/18

CPC classification number: A61B5/14546 ,  A61B5/0071 ,  A61B5/05 ,  A61B5/681 ,  A61B5/7203 ,  A61B5/742

Abstract: A method for modulating a response signal includes introducing functionalized particles into a lumen of subsurface vasculature, wherein the functionalized particles are configured to interact with one or more target analytes present in blood circulating in the subsurface vasculature; and non-invasively detecting the one or more target analytes. A response signal, which may include a background signal and an analyte response signal related to interaction of the functionalized particles with the one or more target analytes, is transmitted from the subsurface vasculature. A modulation configured to alter the response signal such that the analyte response signal is affected differently than the background signal may be applied to a portion of subsurface vasculature. Analyte detection may be achieved by differentiating the analyte response signal from the background signal.

Abstract translation: 用于调节响应信号的方法包括将功能化颗粒引入地下脉管系统的内腔，其中功能化颗粒被配置为与存在于在地下脉管系统中循环的血液中的一种或多种目标分析物相互作用; 并非侵入性地检测一种或多种目标分析物。 响应信号可以包括背景信号和与功能化颗粒与一种或多种目标分析物的相互作用相关的分析物响应信号，从地下脉管系统传输。 被配置为改变响应信号以使得分析物响应信号受影响不同于背景信号的调制可以应用于一部分地下脉管系统。 可以通过将分析物响应信号与背景信号进行微分来实现分析物检测。

公开(公告)号：US20160244165A1

公开(公告)日：2016-08-25

申请号：US15147766

申请日：2016-05-05

Applicant: Google Inc.

Inventor： William Graham Patrick ,  James Ryan Burgess ,  Andrew Conrad

IPC: B64D1/12 ,  B64C39/02

CPC classification number: B64D1/12 ,  B64C39/024 ,  B64C2201/128 ,  B64C2201/141 ,  B64C2201/145 ,  B64D1/22

Abstract: Embodiments described herein may help to provide medical support via a fleet of unmanned aerial vehicles (UAVs). An illustrative UAV may include a housing, a payload, a line-deployment mechanism coupled to the housing and a line, and a payload-release mechanism that couples the line to the payload, wherein the payload-release mechanism is configured to release the payload from the line. The UAV may further include a control system configured to determine that the UAV is located at or near a delivery location and responsively: operate the line-deployment mechanism according to a variable deployment-rate profile to lower the payload to or near to the ground, determine that the payload is touching or is within a threshold distance from the ground, and responsively operate the payload-release mechanism to release the payload from the line.

公开(公告)号：US20150112167A1

公开(公告)日：2015-04-23

申请号：US14061325

申请日：2013-10-23

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters ,  Vikram Singh Bajaj ,  Jason Thompson ,  Mark Askew

IPC: A61B5/05 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14546 ,  A61B5/0022 ,  A61B5/0059 ,  A61B5/0071 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/021 ,  A61B5/024 ,  A61B5/05 ,  A61B5/0515 ,  A61B5/055 ,  A61B5/1455 ,  A61B5/681 ,  A61B5/7228 ,  G01R33/24 ,  G01R33/44 ,  G06F19/00 ,  G16H40/63

Abstract: A system for modulating a response signal includes functionalized particles configured to interact with target analytes, a detector configured to detect an analyte response signal transmitted from the body, a modulation source configured to modulate the analyte response signal, and a processor configured to non-invasively detect the one or more target analytes by differentiating the analyte response signal from a background signal, at least in part, based on the modulation. The analyte response signal is related to the interaction of the target analytes with the functionalized particles. In some examples, the system may also include magnetic particles and a magnetic field source sufficient to distribute the magnetic particles into a spatial arrangement in the body. The analyte response signal may be differentiated from the background signal, at least in part, based on modulation of the signals due, at least in part, to the spatial arrangement of the magnetic particles.

Abstract translation: 用于调制响应信号的系统包括配置成与目标分析物相互作用的功能化颗粒，被配置为检测从身体传输的分析物响应信号的检测器，配置成调制分析物响应信号的调制源和被配置为非侵入性的处理器 至少部分地基于调制，通过将分析物响应信号与背景信号区分开来来检测一种或多种目标分析物。 分析物响应信号与目标分析物与官能化颗粒的相互作用有关。 在一些示例中，该系统还可以包括磁性颗粒和足以将磁性颗粒分布到体内的空间布置的磁场源。 至少部分地基于至少部分地由于至少部分地对磁性颗粒的空间布置的信号的调制而将分析物响应信号与背景信号区分开。

公开(公告)号：US20140378794A1

公开(公告)日：2014-12-25

申请号：US13924145

申请日：2013-06-21

Applicant: Google Inc.

Inventor： Andrew Conrad ,  Eric Peeters

IPC: A61B5/00

CPC classification number: A61B5/681 ,  A61B5/0022 ,  A61B5/02055 ,  A61B5/1455

Abstract: A wearable device includes a detector configured to detect a response signal transmitted from a portion of subsurface vasculature, the response signal being related to binding of a clinically-relevant analyte to functionalized particles present in a lumen of the subsurface vasculature. Program instructions stored in a computer readable medium of the device, and executable by a processor, may cause the device to determine a concentration of the clinically-relevant analyte based on the response signal detected by the detector; determine whether a medical condition is indicated based on at least the concentration of the clinically-relevant analyte; and, in response to a determination that the medical condition is indicated, transmit data representative of the medical condition via the communication interface. The device may also include a signal source configured to transmit an interrogating signal into the portion of subsurface vasculature, thereby generating a response signal in response to the interrogating signal.

Abstract translation: 可穿戴装置包括检测器，其被配置为检测从地下脉管系统的一部分传输的响应信号，所述响应信号与临床相关分析物与存在于地下脉管系统的内腔中的官能化颗粒的结合有关。 存储在设备的计算机可读介质中并且可由处理器执行的程序指令可以使得设备基于由检测器检测到的响应信号来确定临床相关分析物的浓度; 至少基于临床相关分析物的浓度确定是否指示医学状况; 并且响应于指示医疗状况的确定，经由通信接口发送表示医疗状况的数据。 该装置还可以包括被配置为将询问信号发送到地下脉管系统的部分中的信号源，从而响应于询问信号而产生响应信号。