-
公开(公告)号:US20110004006A1
公开(公告)日:2011-01-06
申请号:US12833423
申请日:2010-07-09
申请人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
发明人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
IPC分类号: C07D207/14 , C07C315/04 , C07F7/08 , C07C315/06
CPC分类号: A61K31/40 , A61K31/455 , A61K31/4965 , A61K31/519 , C07D207/12
摘要: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
摘要翻译: 公开了氨基环己基醚化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了化合物和组合物的用途,包括治疗心律失常。
-
公开(公告)号:US08163938B2
公开(公告)日:2012-04-24
申请号:US12833423
申请日:2010-07-09
申请人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
发明人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
IPC分类号: C07D207/12 , A61K31/40
CPC分类号: A61K31/40 , A61K31/455 , A61K31/4965 , A61K31/519 , C07D207/12
摘要: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
摘要翻译: 公开了氨基环己基醚化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了化合物和组合物的用途,包括治疗心律失常。
-
公开(公告)号:US07767830B2
公开(公告)日:2010-08-03
申请号:US11690361
申请日:2007-03-23
申请人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
发明人: Grace Jung , Bertrand M. C. Plouvier , Yuzhong Liu , Jeff Jiqun Zhu , Tao Sheng , Anthony G. M. Barrett , Lewis Siu Leung Choi , Doug Ta Hung Chou
IPC分类号: A61K31/40 , C07D207/12
CPC分类号: A61K31/40 , A61K31/455 , A61K31/4965 , A61K31/519 , C07D207/12
摘要: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
摘要翻译: 公开了氨基环己基醚化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了化合物和组合物的用途,包括治疗心律失常。
-
公开(公告)号:US09115081B2
公开(公告)日:2015-08-25
申请号:US13612559
申请日:2012-09-12
申请人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
发明人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
IPC分类号: C07D207/12 , C07C213/02 , C07C231/12 , C07C269/06 , C07D207/273
CPC分类号: C07D207/12 , C07C213/02 , C07C231/12 , C07C269/06 , C07C2601/14 , C07D207/273 , C07C217/52 , C07C235/40 , C07C271/56
摘要: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
摘要翻译: 公开了制备立体异构基本上为氨基环己基醚化合物如反 - (1R,2R) - 氨基环己基醚化合物和/或反 - (1S,2S) - 氨基环己基醚化合物以及各种中间体和底物的方法。
-
公开(公告)号:US08692002B2
公开(公告)日:2014-04-08
申请号:US11719737
申请日:2005-11-18
申请人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
发明人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
IPC分类号: C07D207/12
CPC分类号: C07D207/12 , C07C213/02 , C07C231/12 , C07C269/06 , C07C2601/14 , C07D207/273 , C07C217/52 , C07C235/40 , C07C271/56
摘要: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
摘要翻译: 公开了制备立体异构基本上为氨基环己基醚化合物如反 - (1R,2R) - 氨基环己基醚化合物和/或反 - (1S,2S) - 氨基环己基醚化合物以及各种中间体和底物的方法。
-
公开(公告)号:US20130102791A1
公开(公告)日:2013-04-25
申请号:US13612559
申请日:2012-09-12
申请人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
发明人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
IPC分类号: C07D207/12
CPC分类号: C07D207/12 , C07C213/02 , C07C231/12 , C07C269/06 , C07C2601/14 , C07D207/273 , C07C217/52 , C07C235/40 , C07C271/56
摘要: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
-
公开(公告)号:US20100152464A1
公开(公告)日:2010-06-17
申请号:US11719737
申请日:2005-11-18
申请人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
发明人: Bertrand M. C. Plouvier , Doug Ta Hung Chou , Grace Jung , Lewis Siu Leung Choi , Tao Sheng , Anthony G. M. Barrett , Marco S. Passafaro , Martin Kurz , Daniel Moeckli , Pirmin Ulmann , Alfred Hedinger
IPC分类号: C07D207/12
CPC分类号: C07D207/12 , C07C213/02 , C07C231/12 , C07C269/06 , C07C2601/14 , C07D207/273 , C07C217/52 , C07C235/40 , C07C271/56
摘要: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
摘要翻译: 公开了制备立体异构基本上为氨基环己基醚化合物如反 - (1R,2R) - 氨基环己基醚化合物和/或反 - (1S,2S) - 氨基环己基醚化合物以及各种中间体和底物的方法。
-
公开(公告)号:US07534790B2
公开(公告)日:2009-05-19
申请号:US11944282
申请日:2007-11-21
申请人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
发明人: Allen I. Bain , Gregory N. Beatch , Cindy J. Longley , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander B. Zolotoy
IPC分类号: A61K31/5375 , A61K31/5377 , A61K31/495 , A61K31/426 , A61K31/403 , A61K31/4015 , A61K31/40 , C07D295/033 , C07D413/02 , C07D295/027 , C07D277/04 , C07D209/96 , C07D207/12
CPC分类号: C07D207/27 , C07C217/52 , C07C2601/14 , C07D207/12 , C07D277/04 , C07D295/08 , C07D295/096 , C07D295/14 , C07D295/15 , C07D295/185 , C07D333/54 , C07D333/56 , C07D491/10
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
-
公开(公告)号:US08008342B2
公开(公告)日:2011-08-30
申请号:US12412010
申请日:2009-03-26
申请人: Gregory N. Beatch , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander R. Zolotoy
发明人: Gregory N. Beatch , Bertrand M. C. Plouvier , Tao Sheng , Michael J. A. Walker , Richard A. Wall , Sandro L. Yong , Jeff Jiqun Zhu , Alexander R. Zolotoy
IPC分类号: A61K31/40
CPC分类号: A61K31/40 , A61K9/0019 , A61K31/4015 , C07D209/36
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
-
公开(公告)号:US07259184B2
公开(公告)日:2007-08-21
申请号:US11342270
申请日:2006-01-27
申请人: Gregory N Beatch , Bertrand M C Plouvier , Tao Sheng , Michael J A Walker , Richard A Wall , Sandro L Yong , Jeff Jiqun Zhu , Alexander B Zolotoy
发明人: Gregory N Beatch , Bertrand M C Plouvier , Tao Sheng , Michael J A Walker , Richard A Wall , Sandro L Yong , Jeff Jiqun Zhu , Alexander B Zolotoy
IPC分类号: A61K31/4025 , C07D207/12
CPC分类号: A61K31/40 , A61K9/0019 , A61K31/4015 , C07D207/12 , C07D209/36
摘要: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
摘要翻译: 公开了离子通道调节化合物。 本发明的化合物可以掺入组合物和试剂盒中。 本发明还公开了用于化合物和组合物的各种体外和体内用途,包括治疗心律失常和产生镇痛和局部麻醉。
-
-
-
-
-
-
-
-
-