-
1.发明申请公开(公告)号：US20130017126A1
公开(公告)日：2013-01-17
申请号：US13474243
申请日：2012-05-17
申请人： Gregory M. Colella , Henry D. Huang , Anthony F. Kuklo, JR. , Dimitri Shishkin , Maria Figueroa , James A. Mawhirt
发明人： Gregory M. Colella , Henry D. Huang , Anthony F. Kuklo, JR. , Dimitri Shishkin , Maria Figueroa , James A. Mawhirt
CPC分类号： G01N33/4905 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L2200/12 , B01L2200/146 , B01L2200/16 , B01L2300/027 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/165 , B01L2400/0487 , B01L2400/086
摘要： An apparatus for measuring blood clotting time includes a blood clot detection instrument and a cuvette for use with the blood clot detection instrument. The cuvette includes a blood sample receptor-inlet; a channel arrangement including at least one test channel for performing a blood clotting time measurement, a sampling channel having at least one surface portion that is hydrophilic, communicating with the blood sample receptor-inlet and the at least one test channel, and a waste channel having at least one surface portion that is hydrophilic, communicating with the sampling channel; and a vent opening communicating with the sampling channel. The sampling channel, the vent opening and the waste channel, coact to automatically draw a requisite volume of a blood sample deposited at the blood receptor-inlet, into the sampling channel.
摘要翻译： 用于测量血液凝固时间的装置包括血块检测仪器和与血块检测仪器一起使用的试管。 比色皿包括血液样本受体 - 入口; 包括用于进行血液凝固时间测量的至少一个测试通道的通道布置，具有至少一个亲水性表面部分，与血液样本受体入口和至少一个测试通道连通的采样通道，以及废物通道 具有至少一个亲水的表面部分，与采样通道连通; 以及与采样通道连通的通风口。 采样通道，通气口和废气通道共同作用，将沉积在血液受体入口处的血液样本的必需体积自动绘制到采样通道中。
-
2.发明申请公开(公告)号：US20100028207A1
公开(公告)日：2010-02-04
申请号：US12503665
申请日：2009-07-15
申请人： Gregory M. Colella , Henry D. Huang , Anthony F. Kuklo, JR. , Dimitri V. Shishkin , Maria Figueroa , James A. Mawhirt
发明人： Gregory M. Colella , Henry D. Huang , Anthony F. Kuklo, JR. , Dimitri V. Shishkin , Maria Figueroa , James A. Mawhirt
CPC分类号： G01N33/4905 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502746 , B01L2200/12 , B01L2200/146 , B01L2200/16 , B01L2300/027 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/165 , B01L2400/0487 , B01L2400/086
摘要： An apparatus for measuring blood clotting time includes a blood clot detection instrument and a cuvette for use with the blood clot detection instrument. The cuvette includes a blood sample receptor-inlet; a channel arrangement including at least one test channel for performing a blood clotting time measurement, a sampling channel having at least one surface portion that is hydrophilic, communicating with the blood sample receptor-inlet and the at least one test channel, and a waste channel having at least one surface portion that is hydrophilic, communicating with the sampling channel; and a vent opening communicating with the sampling channel. The sampling channel, the vent opening and the waste channel, coact to automatically draw a requisite volume of a blood sample deposited at the blood receptor-inlet, into the sampling channel. More specifically, air compressed within the blood clot detection instrument, the at least one test channel of the cuvette, and the section of the sampling channel extending beyond the vent opening of the cuvette, coacts with the waste channel to cause a leading edge of the blood sample drawn into the sampling channel from the blood receptor-inlet, to pull back within the sampling channel and uncover an optical sensor in of the blood clot detection instrument. The uncovering of the optical sensor activates a pump module of the blood clot detection instrument, which draws the requisite volume of the blood sample into the at least one test channel.
摘要翻译： 用于测量血液凝固时间的装置包括血块检测仪器和与血块检测仪器一起使用的试管。 比色皿包括血液样本受体 - 入口; 包括用于进行血液凝固时间测量的至少一个测试通道的通道布置，具有至少一个亲水性表面部分，与血液样本受体入口和至少一个测试通道连通的采样通道，以及废物通道 具有至少一个亲水的表面部分，与采样通道连通; 以及与采样通道连通的通风口。 采样通道，通气口和废气通道共同作用，将沉积在血液受体入口处的血液样本的必需体积自动绘制到采样通道中。 更具体地，在血块检测仪器内压缩的空气，比色皿的至少一个测试通道以及延伸超过比色杯通气口的采样通道的部分与废物通道共同作用， 血液样本从血液受体入口吸入采样通道，在采样通道内拉回，并露出血块检测仪器中的光学传感器。 光学传感器的露出激活血块检测仪器的泵模块，其将血样的必要体积吸入至少一个测试通道。
-
公开(公告)号：US5584846A
公开(公告)日：1996-12-17
申请号：US549173
申请日：1995-10-27
CPC分类号： A61B17/32093 , A61B5/150022 , A61B5/150259 , A61B5/150458 , A61B5/15105 , A61B5/15113 , A61B5/15142 , A61B2090/0814
摘要： A low cost lancet device for creating a skin incision. The lancet contains a unistructurally formed plastic body, thereby making the lancet device easy to manufacture at low cost. The plastic body contains a resilient spring loop that attaches an arm element to an opposing base element. The spring loop is curved, therefore the arm element is retained above the base element by the spring loop. A blade is disposed on the arm element. The blade aligns with a slot in the base element so that when the spring loop is compressed, and the arm element is moved toward the base element, the blade extends through the slot in the base element. A protrusion extends from the base element that obstructs the movement of the arm element toward the base element. As a result, when a force is applied to the arm element, the arm element abuts against the protrusion and applies a bias to the protrusion that acts to displace the protrusion. When a predetermined threshold force is applied to the arm element, the arm element moves past the obstructing protrusion and the arm element rapidly moves toward the base element, compressing the spring loop. As the arm element approaches the base element, the blade on the arm element extends through the slot in the base element and creates the desired incision. Once the applied force is removed from the arm element, the bias of the spring loop moves the arm element away from the base element, thereby retracting the blade back through the slot in the base element.
摘要翻译： 用于创建皮肤切口的低成本柳叶刀装置。 柳叶刀含有非结构形成的塑料体，从而使得柳叶刀器件易于制造成本低廉。 塑料体包含弹性弹簧环，其将臂元件附接到相对的基座元件。 弹簧环是弯曲的，因此臂元件通过弹簧环保持在基座元件的上方。 刀片设置在臂元件上。 叶片与基座元件中的狭槽对准，使得当弹簧环被压缩并且臂元件朝向基座元件移动时，叶片延伸穿过基座元件中的槽。 突起从基部元件延伸，阻止臂元件朝向基座元件的移动。 结果，当向臂元件施加力时，臂元件抵靠突起并且向用于移位突起的突起施加偏压。 当对臂元件施加预定的阈值力时，臂元件移动通过障碍突起，并且臂元件快速朝向基座元件移动，压缩弹簧环。 当臂元件靠近基座元件时，臂元件上的刀片延伸穿过基座元件中的槽并产生所需的切口。 一旦施加的力从臂元件移除，弹簧环的偏压使臂元件远离基座元件移动，从而使刀片通过基座元件中的狭槽回缩。
-
公开(公告)号：US5851215A
公开(公告)日：1998-12-22
申请号：US718773
申请日：1996-09-24
CPC分类号： A61B5/15144 , A61B5/150022 , A61B5/150259 , A61B5/150465 , A61B5/150916 , A61B5/15111 , A61B5/15117
摘要： A low cost safety lancet device for creating a skin incision. The lancet contains a unitarily formed plastic body, thereby making the lancet device easy to manufacture at a low cost. The lancet device includes a blade beam having a cutting blade disposed at one end for generating an incision in a patient's skin. The blade beam is pivotally coupled within the device, engages a beam keeper arm in a first position and disengages the beam keeper arm in a second position. Upon activation of the device, the blade beam member resiliently deflects in a first direction as the beam keeper arm moves from the first position to the second position thereby causing a buildup of a biasing force in the beam member. When the blade beam disengages the beam keeper arm in the second position, the biasing force built up in the beam member causes the beam member to pivot, thereby accelerating the cutting blade through an aperture in the lancet device to incise the user's skin. The acceleration of the blade beam and cutting blade resiliently deflects the blade beam into a second direction, building up a second biasing force which causes the blade beam to return to a non-deflected position thereby withdrawing the cutting blade from the user's skin and back through the aperture.
摘要翻译： 一种用于创建皮肤切口的低成本安全刺血针装置。 柳叶刀包含整体形成的塑料体，从而使得柳叶刀装置以低成本容易制造。 柳叶刀装置包括具有设置在一端的切割刀片的刀片梁，用于在患者皮肤中产生切口。 叶片梁在装置内枢转地联接，使梁保持臂在第一位置接合，并将梁保持臂分离在第二位置。 在激活装置时，当梁保持臂从第一位置移动到第二位置时，叶片梁构件在第一方向弹性地偏转，从而导致梁构件中的偏置力的累积。 当叶片梁在第二位置脱离梁保持臂时，在梁构件中形成的偏压力使梁构件枢转，从而通过刺血针装置中的孔加速切割刀片以切割使用者的皮肤。 叶片梁和切割刀片的加速度将叶片梁弹性地偏转到第二方向，建立第二偏压力，其使叶片梁返回到非偏转位置，从而将切割刀片从使用者的皮肤上撤回并且通过 光圈。
-
公开(公告)号：US5782852A
公开(公告)日：1998-07-21
申请号：US934212
申请日：1997-09-19
CPC分类号： A61B5/15144 , A61B5/150022 , A61B5/150427 , A61B5/150916 , A61B5/15113 , A61B5/15117 , A61B2090/0814
摘要： An apparatus for implementing a skin incision has an incision blade having at least three facets and at least one sharpened apex. Each of the facets narrows down to one of the apexes. A housing having an exterior surface adapted to be placed flush against the skin and an elongated slot located on the exterior of the surface housing the incision blade. A blade pivoting mechanism located in the housing guides the incision blade through the slot. The blade pivoting mechanism has a first end and second end wherein the first end is pivotally coupled to the housing and the second end supports the incision blade. An actuatable depressing mechanism, located within the housing means, engages and holds the blade pivoting mechanism in a set position, preventing the pivotal movement of the blade pivoting mechanism within the housing. When the depressing mechanism is actuated, the blade pivoting mechanism disengages and transverses the sloped surface, displacing the second end of the blade pivoting mechanism toward the elongated slot, such that the multiple facets of the incision blade emerge from the elongated slot and incise the skin.
摘要翻译： 用于实施皮肤切口的装置具有至少具有三个小面和至少一个锐化顶点的切割刀片。 每个方面都缩小到其中一个顶点。 具有适于与皮肤相对放置的外表面的壳体和位于容纳切割刀片的表面的外部上的细长槽。 位于壳体中的刀片枢转机构通过狭槽引导切口刀片。 刀片枢转机构具有第一端和第二端，其中第一端枢转地联接到壳体，并且第二端支撑切口刀片。 位于壳体装置内的致动按压机构将刀片枢转机构接合并保持在设定位置，防止刀片枢转机构在壳体内的枢转运动。 当按压机构被致动时，刀片枢转机构脱离并横向倾斜的表面，使刀片枢转机构的第二端朝向细长槽移动，使得切口刀片的多个面从细长的槽中出来并切开皮肤 。
-
公开(公告)号：US5772677A
公开(公告)日：1998-06-30
申请号：US718774
申请日：1996-09-24
CPC分类号： A61B17/32093
摘要： An apparatus for implementing a skin incision has a torsion spring and a method of assembling the apparatus. The apparatus has a housing having a pair of housing sections, each of the housing section having a base and a plurality of walls. The housing defines an inner space and an exterior. A pivot arm is pivotally mounted to a base of a housing section. The pivot arm is guided between a first position and a second position by a follower in a cam carried by the housing. A torsion spring carried by a spring post is coupled to the arm to exert a spring force on the arm in the first position. The housing has an indentation with a raised level and a lower groove on the base for receiving a portion of the spring post. The opening through the base extends from the lower groove. The spring post has a cylindrical base portion adapted to be received by the indentation in the base and a detent portion. The detent portion has a circular segment detent portion and a turn element accessible from the exterior of the housing. The circular segment detent portion is adapted to engage the raised level of the indentation in the install position and be retained in the lower groove in the loaded position. A trigger mechanism is received in the housing and acts with the pivot arm when activated whereby the arm moves from the first position to the second position due to the spring energy.
-
公开(公告)号：US5630828A
公开(公告)日：1997-05-20
申请号：US633625
申请日：1996-04-17
IPC分类号： A61B5/15 , A61B17/00 , A61B17/125 , A61B19/00 , A61B17/32
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150305 , A61B5/150389 , A61B5/15113 , A61B5/15144 , A61B2017/0023 , A61B2090/0814
摘要： A low cost safety lancet device for creating a skin incision. The lancet contains a unitarily formed plastic body, thereby making the lancet device easy to manufacture at a low cost. The lancet device includes a housing having an internal hollow and a blade beam pivotally disposed within the hollow of the housing for generating an incision in a patient's skin. Upon the activation of the device, the blade beam pivots through a predetermined path which causes a blade associated with the blade beam to travel out of an aperture in the housing to incise the patient's skin. The device further includes a trigger for propelling the blade through the path and a cam projection disposed within the housing which cooperates with the trigger to accelerate the trigger through the hollow of the housing thereby causing the blade to accelerate through the aperture of the housing. A portion of the trigger then unavoidably deflects to automatically allow the blade to retract back into the hollow of the casing after incising the patient's skin.
摘要翻译： 一种用于创建皮肤切口的低成本安全刺血针装置。 柳叶刀包含整体形成的塑料体，从而使得柳叶刀装置以低成本容易制造。 柳叶刀装置包括具有内部中空的壳体和枢转地设置在壳体的中空部内的叶片梁，用于在患者皮肤中产生切口。 在激活装置时，叶片束通过预定的路径枢转，该预定路径使得与叶片梁相关联的叶片移出外壳中的孔，以切开病人的皮肤。 该装置还包括用于通过路径推动叶片的触发器和设置在壳体内的凸轮突起，其与触发器配合，以通过壳体的中空加速触发器，从而使得叶片通过壳体的孔加速。 然后触发器的一部分不可避免地偏转以自动允许刀片在切开患者皮肤之后缩回到套管的中空部分中。
-
公开(公告)号：US6010519A
公开(公告)日：2000-01-04
申请号：US22072
申请日：1998-02-11
IPC分类号： A61B17/32
CPC分类号： A61B17/32093
摘要： An apparatus for implementing a skin incision has a torsion spring and a method of assembling the apparatus. The apparatus has a housing having a pair of housing sections, each of the housing section having a base and a plurality of walls. The housing defines an inner space and an exterior. A pivot arm is pivotally mounted to a base of a housing section. The pivot arm is guided between a first position and a second position by a follower in a cam carried by the housing. A torsion spring carried by a spring post is coupled to the arm to exert a spring force on the arm in the first position. The housing has an indentation with a raised level and a lower groove on the base for receiving a portion of the spring post. The opening through the base extends from the lower groove. The spring post has a cylindrical base portion adapted to be received by the indentation in the base and a detent portion. The detent portion has a circular segment detent portion and a turn element accessible from the exterior of the housing. The circular segment detent portion is adapted to engage the raised level of the indentation in the install position and be retained in the lower groove in the loaded position. A trigger mechanism is received in the housing and acts with the pivot arm when activated whereby the arm moves from the first position to the second position due to the spring energy.
摘要翻译： 用于实施皮肤切口的装置具有扭转弹簧和组装该装置的方法。 该装置具有壳体，该壳体具有一对壳体部分，每个壳体部分具有基部和多个壁。 壳体限定内部空间和外部。 枢转臂枢转地安装到壳体部分的基部。 枢转臂在由壳体承载的凸轮中的从动件在第一位置和第二位置之间被引导。 由弹簧支架承载的扭转弹簧联接到臂上，以在第一位置上在臂上施加弹簧力。 壳体具有升高的压痕和底座上的下槽，用于容纳弹簧柱的一部分。 通过基座的开口从下槽延伸。 弹簧柱具有适于被基座中的凹陷接收的圆柱形基部和止动部。 止动部分具有圆形段止动部分和可从壳体的外部接近的转向元件。 圆形段止动部分适于在安装位置接合压痕的升高水平并且在加载位置中保持在下槽中。 触发机构被容纳在壳体中并且当被激活时与枢转臂一起作用，由此由于弹簧能量，臂从第一位置移动到第二位置。
-
公开(公告)号：US5571132A
公开(公告)日：1996-11-05
申请号：US465686
申请日：1995-06-06
CPC分类号： A61B5/15144 , A61B5/150022 , A61B5/150259 , A61B5/150435 , A61B5/150549 , A61B5/150618 , A61B5/150717 , A61B5/15113 , A61B5/15128 , A61B5/15142
摘要： A self-activated blood drop generator device comprising a casing having an internal hollow and blade assembly disposed within the hollow of the casing for generating an incision in a patient's skin. The device includes a fork-shaped triggering mechanism coupled to the blade assembly for propelling the blade assembly through a predetermined path. A cam arrangement associated with the casing causes the cutting portion of the blade assembly to travel through an arcuate scapel-like path as the cutting portion passes through an aperture in the casing. A retractor arrangement associated with the casing, the blade assembly and the triggering mechanism, are provided for retracting the blade assembly into the hollow of the casing. Also provided is accelerator arrangement associated with the casing and the triggering mechanism for accelerating the triggering mechanism through the hollow of the casing thereby causing the blade assembly to accelerate through the predetermined path. The activation of the device causes the cutting portion of the blade to travel out of the hollow of the casing through the aperture to incise the patient's skin and then retract back through the aperture into the hollow of the casing.
摘要翻译： 一种自激活血滴发生器装置，包括具有设置在壳体的中空部内的内部中空和叶片组件的壳体，用于在患者皮肤中产生切口。 该装置包括联接到叶片组件的叉状触发机构，用于通过预定路径推动叶片组件。 与壳体相关联的凸轮装置使得当切割部分穿过壳体中的孔时，刀片组件的切割部分行进通过弓形的踏板状路径。 设置有与壳体，叶片组件和触发机构相关联的牵开器装置，用于将叶片组件缩回到壳体的中空部分中。 还提供了与壳体相关联的加速器布置和用于通过壳体的中空加速触发机构的触发机构，从而使叶片组件通过预定路径加速。 装置的激活导致叶片的切割部分通过孔从壳体的中空行进出去，以切开患者的皮肤，然后通过孔缩回到壳体的中空部分中。
-
公开(公告)号：US07379167B2
公开(公告)日：2008-05-27
申请号：US10364256
申请日：2003-02-11
申请人： James A. Mawhirt , Ted Lee , Supinan R. Naphuket , Charles E. Toms , Wai Law , Catherine Cimini
发明人： James A. Mawhirt , Ted Lee , Supinan R. Naphuket , Charles E. Toms , Wai Law , Catherine Cimini
CPC分类号： G01N21/8483 , B01L3/5023 , B01L2200/026 , B01L2300/0825 , G01N33/721
摘要： The apparatus and method for quickly measuring the hemoglobin content of a sample of blood uses a light reflectance measurement of the hemoglobin sample lysed in a membrane. The reflection is inversely proportional to hemoglobin concentration. A blood sample is loaded on to a nylon mesh and dispersed within a nylon membrane, both of which have been treated with a hemolyzing agent and surfactant, and air-dried. As soon as the blood sample contacts the reagent on the membrane, the red blood cells are lysed and the hemoglobin molecules are released and dispersed into the membrane by the action of surfactant. The hemoglobin apparatus emits light at 522 nm to the reflective surface of the membrane. The intensity of the reflected light is measured by a detector in less than 29 seconds. The intensity of the reflected light is converted to hemoglobin concentration, g/dL, or mmol/L by an interpolative comparison with stored reflection data indicative of known hemoglobin contents.
摘要翻译： 用于快速测量血液样本血红蛋白含量的装置和方法使用在膜中裂解的血红蛋白样品的光反射测量。 反射与血红蛋白浓度成反比。 将血液样品装载到尼龙网上并分散在尼龙膜中，两者均用溶血剂和表面活性剂处理，并风干。 一旦血液样品与膜上的试剂接触，红细胞就被溶解，血红蛋白分子通过表面活性剂释放并分散到膜中。 血红蛋白装置在522nm处发射光到膜的反射表面。 反射光的强度由检测器在不到29秒内测量。 通过与指示已知血红蛋白含量的存储反射数据进行内插比较，将反射光的强度转换为血红蛋白浓度g / dL或mmol / L。
-
-
-
-
-
-
-
-
-
搜索结果
29 条记录 (耗时 0.032 秒)
