公开(公告)号：US20050192230A1

公开(公告)日：2005-09-01

申请号：US11040273

申请日：2005-01-20

申请人： Guenter Linz ,  Wolfgang Broeder ,  Georg Zerban ,  Eric Winter ,  Bernd Schmitt ,  Svenja Renner ,  Bjoern Weyell ,  Heinz-Peter Schmitt

发明人： Guenter Linz ,  Wolfgang Broeder ,  Georg Zerban ,  Eric Winter ,  Bernd Schmitt ,  Svenja Renner ,  Bjoern Weyell ,  Heinz-Peter Schmitt

IPC分类号： A61K38/04 ,  C07K5/04

CPC分类号： C07K5/06191 ,  A61K38/00

摘要： The present application relates to a process for preparing the CGRP-antagonist 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine of formula by means of which this compound can be prepared in large amounts, in high yields and with high purity.

摘要翻译： 本申请涉及制备CGRP拮抗剂1- [N 2 - [3,5-二溴-N - [[4-（3,4-二氢-2（1H） - 氧代喹唑啉-3-基）-1-哌啶基]羰基] -D-酪氨酰基] -L-赖氨酰基] -4-（4-吡啶基） - 哌嗪，其中该化合物可以大量制备， 产量高，纯度高。

公开(公告)号：US20140166861A1

公开(公告)日：2014-06-19

申请号：US13985961

申请日：2011-12-29

申请人： Bernd Schmitt ,  Anna Bergamaschi ,  Aldo Mozzanica ,  Roberto Dinapoli

发明人： Bernd Schmitt ,  Anna Bergamaschi ,  Aldo Mozzanica ,  Roberto Dinapoli

IPC分类号： G01T1/29

CPC分类号： G01T1/29 ,  G01T1/247 ,  H04N5/32 ,  H04N5/37455

摘要： A single photon counting detector system has a layer of photosensitive material and an N×M array of photo-detector diodes. Each photo-detector diode has a bias potential interface and a diode output interface. The bias potential interface is connected to bias potential. An N×M array of high gain, low noise readout unit cells is provided, one readout unit cell for each photo-detector diode. Each readout unit cell has an input interface connected to the diode output interface, a high-gain voltage amplifier with an integration capacitor at least two parallel lines of digital counters, each having a comparator with an individually selectable threshold and a gateable section to determine the counting intervals of the digital counters. A multiplexer allows access to the readout cell unit either on a per pixel basis or for several pixels in parallel to read out the digital counter to a data processor transferring the data off chip.

摘要翻译： 单光子计数检测器系统具有感光材料层和N×M光电二极管阵列。 每个光检测器二极管都有一个偏置电位接口和一个二极管输出接口。 偏置电位接口连接到偏置电位。 提供了一个N×M阵列的高增益低噪声读出单位单元，每个光检测二极管一个读出单元。 每个读出单元具有连接到二极管输出接口的输入接口，具有积分电容器的至少两个并行数字计数器的高增益电压放大器，每个具有可独立选择的阈值的比较器和用于确定 计数数字计数器的间隔。 多路复用器允许以每像素为基础访问读出单元单元或者并行地访问几个像素，以将数字计数器读出到将芯片上的数据传输到数据处理器。

公开(公告)号：US08039784B2

公开(公告)日：2011-10-18

申请号：US12085337

申请日：2006-11-20

申请人： Bernd Schmitt

发明人： Bernd Schmitt

IPC分类号： H01L31/00

CPC分类号： H01L27/1446 ,  H01L31/101

摘要： A readout chip for single photon counting has a plurality of N individually working channels each assigned to a respective detector diode. Each channel has a counter designed as a binary counter having a length of M bits and a number of programmable bits. Further, the readout chip has a serial shift register or parallel data input register for entering values for the counter and the programmable bits, and a number of data output shift registers each having a number of K data outputs. Means are provided for selectively multiplexing each of the K data outputs onto a selectable bit of the data output shift register.

摘要翻译： 用于单光子计数的读出芯片具有分配给相应的检测器二极管的多个N个单独的工作通道。 每个通道具有被设计为具有M位长度和可编程位数的二进制计数器的计数器。 此外，读出芯片具有用于输入计数器和可编程位的值的串行移位寄存器或并行数据输入寄存器，以及每个具有多个K个数据输出的多个数据输出移位寄存器。 提供了用于将K个数据输出中的每一个选择性地复用到数据输出移位寄存器的可选择位上的装置。

公开(公告)号：US20090285352A1

公开(公告)日：2009-11-19

申请号：US12085337

申请日：2006-11-20

申请人： Bernd Schmitt

发明人： Bernd Schmitt

IPC分类号： G11C19/00

CPC分类号： H01L27/1446 ,  H01L31/101

摘要： A readout chip for single photon counting has a plurality of N individually working channels each assigned to a respective detector diode. Each channel has a counter designed as a binary counter having a length of M bits and a number of programmable bits. Further, the readout chip has a serial shift register or parallel data input register for entering values for the counter and the programmable bits, and a number of data output shift registers each having a number of K data outputs. Means are provided for selectively multiplexing each of the K data outputs onto a selectable bit of the data output shift register.

摘要翻译： 用于单光子计数的读出芯片具有分配给相应的检测器二极管的多个N个单独的工作通道。 每个通道具有被设计为具有M位长度和可编程位数的二进制计数器的计数器。 此外，读出芯片具有用于输入计数器和可编程位的值的串行移位寄存器或并行数据输入寄存器，以及每个具有多个K个数据输出的多个数据输出移位寄存器。 提供了用于将K个数据输出中的每一个选择性地复用到数据输出移位寄存器的可选择位上的装置。

公开(公告)号：US06398172B1

公开(公告)日：2002-06-04

申请号：US09341247

申请日：1999-07-15

申请人： Heinz Rousek ,  Bernd Schmitt ,  Rainer Weigl ,  Matthias Weller

发明人： Heinz Rousek ,  Bernd Schmitt ,  Rainer Weigl ,  Matthias Weller

IPC分类号： F16L300

CPC分类号： F16M13/02 ,  F16M11/10 ,  F16M11/2014 ,  F16M11/42 ,  F16M13/027 ,  F16M2200/044 ,  F16M2200/065 ,  F21L14/04 ,  F21S6/00 ,  F21S8/036 ,  F21S8/043 ,  F21V21/28

摘要： The support for a load, particularly a lamp, includes a standard spring-loaded arm (3) which is pivotable about a vertical axis and vertically adjustable for holding and positioning the load (4). The spring-loaded arm (3) is connected with other parts (9,8) of the support by engagement of an upwardly directed pin-shaped connector element (5) in a downwardly directed connector pipe or socket section (6), so that the spring-loaded arm (3) is suspended from the other parts. The spring-loaded arm (3) with the upwardly directed pin-shaped connector element (5) has universal applicability in a variety of supports including ceiling or wall supports, which have a cantilever arm (8) from which the connector pipe section (6) extends downwardly, and floor or table supports, which have a stand (14,22) and a support tube (9) extending upward from the stand and having a curved section (10) to which the connector pipe section (6) is attached.

摘要翻译： 负载，特别是灯的支撑件包括标准的弹簧加载臂（3），其可绕垂直轴线枢转并且可垂直调节以保持和定位负载（4）。 弹簧加载的臂（3）通过向上指向的针形连接器元件（5）接合在向下指向的连接器管或插座部分（6）中而与支撑件的其他部分（9,8）连接，使得 弹簧加载臂（3）从其他部分悬挂。 具有向上指向的销状连接器元件（5）的弹簧加载臂（3）在各种支撑件中具有通用性，包括天花板或壁支撑件，其具有悬臂（8），连接管部分 ）向下延伸的地板或桌子支撑件，其具有从支架向上延伸的支架（14,22）和支撑管（9），并具有弯曲部分（10），连接管部分（6）连接到该弯曲部分 。

公开(公告)号：US09121955B2

公开(公告)日：2015-09-01

申请号：US13985961

申请日：2011-12-29

申请人： Bernd Schmitt ,  Anna Bergamaschi ,  Aldo Mozzanica ,  Roberto Dinapoli

发明人： Bernd Schmitt ,  Anna Bergamaschi ,  Aldo Mozzanica ,  Roberto Dinapoli

IPC分类号： G01T1/29 ,  G01T1/24 ,  H04N5/32 ,  H04N5/3745

CPC分类号： G01T1/29 ,  G01T1/247 ,  H04N5/32 ,  H04N5/37455

摘要： A single photon counting detector system has a layer of photosensitive material and an N×M array of photo-detector diodes. Each photo-detector diode has a bias potential interface and a diode output interface. The bias potential interface is connected to bias potential. An N×M array of high gain, low noise readout unit cells is provided, one readout unit cell for each photo-detector diode. Each readout unit cell has an input interface connected to the diode output interface, a high-gain voltage amplifier with an integration capacitor at least two parallel lines of digital counters, each having a comparator with an individually selectable threshold and a gateable section to determine the counting intervals of the digital counters. A multiplexer allows access to the readout cell unit either on a per pixel basis or for several pixels in parallel to read out the digital counter to a data processor transferring the data off chip.

摘要翻译： 单光子计数检测器系统具有感光材料层和N×M光电二极管阵列。 每个光检测器二极管都有一个偏置电位接口和一个二极管输出接口。 偏置电位接口连接到偏置电位。 提供了一个N×M阵列的高增益低噪声读出单位单元，每个光检测二极管一个读出单元。 每个读出单元具有连接到二极管输出接口的输入接口，具有积分电容器的至少两个并行数字计数器的高增益电压放大器，每个具有可独立选择的阈值的比较器和用于确定 计数数字计数器的间隔。 多路复用器允许以每像素为基础访问读出单元单元或者并行地访问几个像素，以将数字计数器读出到将芯片上的数据传输到数据处理器。

公开(公告)号：US08600792B2

公开(公告)日：2013-12-03

申请号：US12977064

申请日：2010-12-23

申请人： Bernhard Drittler ,  Ralf Ehret ,  Jens-Christoph Nolte ,  Bernd Schmitt

发明人： Bernhard Drittler ,  Ralf Ehret ,  Jens-Christoph Nolte ,  Bernd Schmitt

IPC分类号： G06Q10/00

CPC分类号： G06Q10/063

摘要： Various embodiments of systems and methods for providing business process visibility at real time are described herein. One or more business activity events are received at a local business activity event manager. Further, business process binding information associated with the one or more business activity events is retrieved at the business activity manager from a business process model manager. A relationship of the one or more business activity events with a business process using the business process binding is identified at the business activity event manager. Upon determination, a business process log manager is triggered for logging a business activity log of a business process instance at real time. Furthermore, the business activity log is extracted to monitor and analyze the business process instance at real time.

摘要翻译： 这里描述了用于实时提供业务过程可视性的系统和方法的各种实施例。 一个或多个业务活动事件在本地业务活动事件管理器处收到。 此外，业务活动管理器从业务流程模型管理器检索与一个或多个业务活动事件相关联的业务流程绑定信息。 业务活动事件管理器识别一个或多个业务活动事件与使用业务流程绑定的业务流程的关系。 一旦确定，触发业务流程日志管理器即可实时记录业务流程实例的业务活动日志。 此外，提取业务活动日志以实时监控和分析业务流程实例。

公开(公告)号：US08255138B2

公开(公告)日：2012-08-28

申请号：US12601362

申请日：2008-05-16

申请人： Thomas Bach ,  Michael Bleser ,  Harald Thelen ,  Elmar Hoffmann ,  Bernd Schmitt

发明人： Thomas Bach ,  Michael Bleser ,  Harald Thelen ,  Elmar Hoffmann ,  Bernd Schmitt

IPC分类号： B60T7/12

CPC分类号： B60W30/18118 ,  B60T7/12 ,  B60T2201/04 ,  B60T2201/06 ,  B60W10/06 ,  B60W10/184 ,  B60W2550/142 ,  B60W2720/106 ,  Y10T477/80 ,  Y10T477/84

摘要： A method for starting a motor vehicle, which is held at a standstill on an inclined route by a brake force which is maintained independently of the driver, after a predetermined holding time has elapsed gradually reduces the brake force which is generated independently of the driver, to put the motor vehicle into motion, and then controls the movement of the motor vehicle, corresponding to a preset course.

摘要翻译： 通过在预定的保持时间过去之后，通过独立于驾驶员的制动力在倾斜的路线上停止的机动车辆的方法逐渐减小独立于驾驶员产生的制动力， 使机动车辆运动，然后控制机动车辆的运动，对应于预设路线。

公开(公告)号：US20100292902A1

公开(公告)日：2010-11-18

申请号：US12601369

申请日：2008-05-16

申请人： Thomas Bach ,  Michael Bleser ,  Harald Thelen ,  Elmar Hoffmann ,  Bernd Schmitt

发明人： Thomas Bach ,  Michael Bleser ,  Harald Thelen ,  Elmar Hoffmann ,  Bernd Schmitt

IPC分类号： B60W10/04 ,  B60W30/18 ,  G06F19/00

CPC分类号： B60T8/24 ,  B60T7/122 ,  B60T2201/04 ,  B60T2201/06

摘要： A method for starting a motor vehicle on a downhill route from an idle state includes the steps of maintaining a sufficient brake force to hold the motor vehicle in the idle state, even if brake actuation by the driver is withdrawn; detecting a wish by the driver to drive off; reducing, independently of the driver, the brake force which is maintained independently of the driver, in such a way that the resulting movement of the motor vehicle follows a preset course.

摘要翻译： 一种用于从空闲状态起动下坡路的机动车辆的方法包括以下步骤：即使撤销驾驶员的制动器致动，也能够保持足够的制动力来保持机动车辆处于怠速状态; 检测驾驶员离开的愿望; 独立于驾驶员的方式减小独立于驾驶员保持的制动力，使得机动车辆的所得运动遵循预设路线。

公开(公告)号：US07514688B2

公开(公告)日：2009-04-07

申请号：US10539837

申请日：2003-08-11

申请人： Christian Broennimann ,  Bernd Schmitt

发明人： Christian Broennimann ,  Bernd Schmitt

IPC分类号： G01T1/20

CPC分类号： H01L27/14661

摘要： The invention is directed to increasing the time resolution capabilities of a photon counting imaging device. This is achieved by a photon-counting imaging device for single x-ray counting, including: a layer of photosensitive material; an N×M array of photodetector diodes arranged in the layer of the photosensitive material; an N×M array of readout unit cells including an high gain, low noise amplifying elements, one readout unit cell for each photodetector diode; the readout unit cells being controlled by a data processing elements; each readout unit cell comprising an internal data processing elements allowing to assign an output signal representing an amplifyied signal of the electron hole pairs generated by an incident photon or a predetermined number of incident photons in the respective photodetector diode to a preselectable region of interest; and the assignment of the output signal is accompanied by a time stamp generated by a clock means.

摘要翻译： 本发明旨在增加光子计数成像装置的时间分辨能力。 这通过用于单次x射线计数的光子计数成像装置来实现，包括：感光材料层; 布置在感光材料层中的N×M阵列的光检测器二极管; 包括高增益，低噪声放大元件的读出单元单元的N×M阵列，每个光电二极管的一个读出单元; 所述读出单元由数据处理元件控制; 每个读出单元包括内部数据处理元件，其允许将表示由相应光电二极管中的入射光子或预定数量的入射光子产生的电子空穴对的放大信号的输出信号分配给预选的感兴趣区域; 并且输出信号的分配伴随着由时钟装置产生的时间戳。