Use of Unsaturated Quionoline or Naphtalene Derivatives as Medicaments
    5.
    发明申请
    Use of Unsaturated Quionoline or Naphtalene Derivatives as Medicaments 审中-公开
    使用不饱和喹啉或萘衍生物作为药物

    公开(公告)号:US20090036484A1

    公开(公告)日:2009-02-05

    申请号:US11718176

    申请日:2005-10-26

    申请人: Hakan Bladh

    发明人: Hakan Bladh

    IPC分类号: A61K31/47 A61P29/00

    CPC分类号: C07D215/08

    摘要: A compound of formula (I): (I), or a pharmaceutically acceptable salt thereof; for use as a medicament (for example modulating the glucocorticoid receptor in a warm blooded animal), and pharmaceutical compositions comprising such compounds.

    摘要翻译: 式(I)化合物:(I)或其药学上可接受的盐; 用作药物(例如调节温血动物中的糖皮质激素受体)和包含这些化合物的药物组合物。

    Quinoline derivatives as neutrophil elastase inhibitors and their use
    6.
    发明申请
    Quinoline derivatives as neutrophil elastase inhibitors and their use 审中-公开
    喹啉衍生物作为嗜中性粒细胞弹性蛋白酶抑制剂及其应用

    公开(公告)号:US20070010551A1

    公开(公告)日:2007-01-11

    申请号:US10569571

    申请日:2004-08-25

    IPC分类号: A61K31/4704 C07D215/233

    摘要: There are provided novel compounds of formula (I) wherein R1, R3, R4, R5, G1, G2, L and n are as defined in the Specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of neutrophil elastase.

    摘要翻译: 提供式(I)的新化合物,其中R 1,R 3,R 4,R 5, ,G 1,G 2,L和n如本说明书和光学异构体,外消旋体和互变异构体及其药学上可接受的盐所定义; 以及其制备方法,含有它们的组合物及其在治疗中的用途。 这些化合物是嗜中性粒细胞弹性蛋白酶抑制剂。