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公开(公告)号：US20110177972A1
公开(公告)日：2011-07-21
申请号：US13033088
申请日：2011-02-23
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas Wu
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4713 , G01N33/564
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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2.发明申请公开(公告)号：US20110110938A1
公开(公告)日：2011-05-12
申请号：US12925947
申请日：2010-11-02
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas D. Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , G01N33/53 , C40B30/04 , G01N33/68 , A61P17/06 , A61P11/06 , A61P19/02 , A61P3/10 , A61P29/00 , A61P17/00 , A61P37/08 , A61P37/06 , A61P7/06 , A61P13/12 , A61P25/00
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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公开(公告)号：US20090155263A1
公开(公告)日：2009-06-18
申请号：US12315879
申请日：2008-12-05
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas D. Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill R. Schoenfeld , William I. Wood , Thomas D. Wu
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
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4.发明申请COMPOSITIONS AND METHODS FOR THE TREATMENT OF NATURAL KILLER CELL RELATED DISEASES 审中-公开用于治疗自然杀伤细胞相关疾病的组合物和方法公开(公告)号：US20110182889A1
公开(公告)日：2011-07-28
申请号：US12979877
申请日：2010-12-28
申请人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
发明人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , C12Q1/68 , G01N33/68 , C40B30/04 , A61K39/00 , A61P37/04 , A61P37/06 , A61P29/00 , A61P19/10 , A61P19/02 , A61P3/10 , A61P25/00 , A61P25/02 , A61P1/16 , A61P31/12 , A61P1/00 , A61P17/00 , A61P11/00
CPC分类号： G01N33/54353 , B01J19/0046 , B01J2219/00378 , B01J2219/00385 , B01J2219/00427 , B01J2219/00529 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/00722 , B82Y30/00 , C03C17/3405 , C12Q1/6837 , C40B40/06 , C40B60/14 , G01N33/6893 , G01N2800/24
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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5.发明申请Compositions and methods for the treatment of natural killer cell related diseases 审中-公开用于治疗自然杀伤细胞相关疾病的组合物和方法公开(公告)号：US20090232802A1
公开(公告)日：2009-09-17
申请号：US12228137
申请日：2008-08-08
申请人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
发明人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Mickey Williams , William I. Wood , Thomas D. Wu
IPC分类号： A61K39/395 , C12Q1/68 , G01N33/566 , A61P19/02 , A61P37/06 , A61P37/02 , A61P17/06 , A61P17/00 , A61P11/06
CPC分类号： G01N33/54353 , B01J19/0046 , B01J2219/00378 , B01J2219/00385 , B01J2219/00427 , B01J2219/00529 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/00722 , B82Y30/00 , C03C17/3405 , C12Q1/6837 , C40B40/06 , C40B60/14 , G01N33/6893 , G01N2800/24
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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6.发明申请公开(公告)号：US20070248588A1
公开(公告)日：2007-10-25
申请号：US10527470
申请日：2003-09-10
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , Mickey Williams , William Wood , Thomas Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , Mickey Williams , William Wood , Thomas Wu
IPC分类号： A61K39/395 , C07H21/04 , C07K14/00 , C07K16/18 , C12N15/00 , C12N5/06 , C12P1/04 , C12Q1/68 , G01N33/53
CPC分类号： C12Q1/6883 , A61K2039/505 , C07K14/47 , C12Q2600/158 , G01N33/564 , G01N2500/10
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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7.发明申请Novel compositions and methods for the treatment of immune related diseases 审中-公开用于治疗免疫相关疾病的新型组合物和方法公开(公告)号：US20070010434A1
公开(公告)日：2007-01-11
申请号：US10528260
申请日：2003-09-15
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , William Wood , Thomas Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , William Wood , Thomas Wu
CPC分类号： C07K14/705 , A61K38/00 , C07K14/47
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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8.发明申请Compositions and methods for the treatmetn of natural killer cell related diseases 审中-公开用于治疗自然杀伤细胞相关疾病的组合物和方法公开(公告)号：US20070037148A1
公开(公告)日：2007-02-15
申请号：US10533416
申请日：2003-11-06
申请人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
发明人： Sherman Fong , Kathryn Dennis , Hilary Clark , Henry Chiu , Jill Schoenfeld , P. Williams , William Wood , Thomas Wu
CPC分类号： G01N33/54353 , B01J19/0046 , B01J2219/00378 , B01J2219/00385 , B01J2219/00427 , B01J2219/00529 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/00637 , B01J2219/00677 , B01J2219/00722 , B82Y30/00 , C03C17/3405 , C12Q1/6837 , C40B40/06 , C40B60/14 , G01N33/6893 , G01N2800/24
摘要： Compositions and methods for improving detection sensitivity in nucleic acid microarray analysis are disclosed, including methods of purifying nucleic acids, methods of synthesizing fluorescent DNA probes, methods of hybridization, and methods of activating a substrate for target molecule attachment are disclosed.
摘要翻译： 公开了用于提高核酸微阵列分析中检测灵敏度的组合物和方法，包括纯化核酸的方法，合成荧光DNA探针的方法，杂交方法和激活靶分子连接底物的方法。
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公开(公告)号：US20070298036A1
公开(公告)日：2007-12-27
申请号：US11843587
申请日：2007-08-22
申请人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , William Wood , Thomas Wu
发明人： Henry Chiu , Hilary Clark , Kathryn Dennis , Sherman Fong , Jill Schoenfeld , William Wood , Thomas Wu
IPC分类号： A61K39/395 , A61K38/00 , C07K16/18 , C12N1/00 , C12N1/20 , C12N15/00 , C12N15/11 , C12N5/06 , C12P21/06 , C12Q1/68 , G01N33/53
CPC分类号： C07K14/47 , A61K38/00 , C07K14/4713 , G01N33/564
摘要： The present invention relates to compositions containing novel proteins and methods of using those compositions for the diagnosis and treatment of immune related diseases.
摘要翻译： 本发明涉及含有新蛋白质的组合物和使用这些组合物来诊断和治疗免疫相关疾病的方法。
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10.发明申请公开(公告)号：US20060210556A1
公开(公告)日：2006-09-21
申请号：US10554680
申请日：2004-04-08
申请人： Daryl Baldwin , Hilary Clark , Henry Chiu , Grazyna Fedorowicz , Sherman Fong , J. Grimaldi , Wenjun Quyang , P. Williams
发明人： Daryl Baldwin , Hilary Clark , Henry Chiu , Grazyna Fedorowicz , Sherman Fong , J. Grimaldi , Wenjun Quyang , P. Williams
IPC分类号： A61K39/395 , A61K39/00 , G01N33/567 , C07H21/04 , C12P21/06 , C07K14/74 , C07K16/28
CPC分类号： G01N33/56972 , C07K14/47 , G01N33/6863 , G01N2500/00 , G01N2800/24
摘要： The present invention relates to compositions of matter and methods for the treatment and diagnosis of immune related diseases, including those mediated by cytokines released primarily either Th1 or Th2 cells in response to antigenic stimulation. The present invention further relates to methods for biasing the differentiation of T-cells in either the Th1 subtype or the Th2 subtype based on the relative expression levels of the gene PRO92726, and its agonists or antagonists. The present invention further relates to a method of diagnosing Th1- and Th2-mediated diseases.
摘要翻译： 本发明涉及用于治疗和诊断免疫相关疾病的物质组合物和方法，包括由主要由Th1或Th2细胞响应于抗原性刺激释放的细胞因子介导的物质组成。 本发明还涉及基于PRO92726及其激动剂或拮抗剂的相对表达水平来偏置Th1亚型或Th2亚型中T细胞分化的方法。 本发明还涉及诊断Th1-和Th2介导的疾病的方法。
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