Recombinant human immunodeficiency virus producing cell lines
    2.
    发明授权
    Recombinant human immunodeficiency virus producing cell lines 失效
    重组人免疫缺陷病毒产生细胞系

    公开(公告)号:US6048725A

    公开(公告)日:2000-04-11

    申请号:US913705

    申请日:1997-09-12

    摘要: Recombinant human immunodeficiency virus producing cell that is obtained by introducing into an animal cell a recombinant human immunodeficiency virus helper plasmid containing at least the sequences of gag, pol and env genes encoded by a human immunodeficiency virus genome and being deficient of a packaging signal and which sustains said genes stably.The human immunodeficiency virus producing cell of the invention is capable of large-scale and consistent preparation of HIV vectors more efficiently than in the prior art.

    摘要翻译: PCT No.PCT / JP96 / 00653 Sec。 371日期:1997年9月12日 102(e)日期1997年9月12日PCT 1996年3月15日PCT公布。 公开号WO96 / 29393 日期1996年9月26日通过将至少包含由人免疫缺陷病毒基因组编码的gag,pol和env基因序列的重组人免疫缺陷病毒辅助质粒导入动物细胞而获得的重组人免疫缺陷病毒产生细胞, 一种包装信号,并稳定地维持所述基因。 本发明的人体免疫缺陷病毒产生细胞能够比现有技术更有效地大规模和一致地制备HIV载体。

    Monoclonal antibody specifically recognizing adeno-associated virus cap
protein
    3.
    发明授权
    Monoclonal antibody specifically recognizing adeno-associated virus cap protein 失效
    特异性识别腺相关病毒帽蛋白的单克隆抗体

    公开(公告)号:US6093534A

    公开(公告)日:2000-07-25

    申请号:US913667

    申请日:1997-09-11

    摘要: A monoclonal antibody specifically recognizing adeno-associated virus CAP protein, which is produced by hybridomas obtained by fusing lymphocytes prepared from a mammal which has been immunized with the adeno-associated virus CAP protein or a recombinant thereof as an antigen with a myeloma cell line. The monoclonal antibody of the present invention is a novel antibody and capable of specifically recognizing the adeno-associated virus CAP protein. Thus, it is applicable to the detection of the adeno-associated virus and the purification of adeno-associated virus vectors for gene therapy.

    摘要翻译: PCT No.PCT / JP96 / 00655 Sec。 371日期:1997年9月11日 102(e)1997年9月11日PCT PCT 1996年3月15日PCT公布。 WO96 / 29349 PCT公开号 日期1996年9月26日一种特异性识别腺相关病毒CAP蛋白的单克隆抗体,其通过将由已经用腺相关病毒CAP蛋白免疫的哺乳动物制备的淋巴细胞或其重组体作为抗原融合获得的杂交瘤产生, 骨髓瘤细胞系。 本发明的单克隆抗体是新型抗体,能够特异性识别腺相关病毒CAP蛋白。 因此,适用于腺相关病毒的检测和用于基因治疗的腺相关病毒载体的纯化。

    Hybrid vehicle drive device
    4.
    发明授权
    Hybrid vehicle drive device 有权
    混合动力车辆驱动装置

    公开(公告)号:US09333848B2

    公开(公告)日:2016-05-10

    申请号:US14378144

    申请日:2012-02-14

    摘要: A hybrid vehicle drive unit including a first planetary gear mechanism; a second planetary gear mechanism; a clutch; and a brake, wherein a first sun gear that is a sun gear of the first planetary gear mechanism is connected to a first rotating electric machine, a first ring gear that is a ring gear of the first planetary gear mechanism is connected to an engine, and a first carrier that is a carrier of the first planetary gear mechanism is connected to a second rotating element of the second planetary gear mechanism and to driving wheels, a first rotating element of the second planetary gear mechanism is connected to the engine and the first ring gear via the clutch, and a third rotating element is connected to a second rotating electric machine, the first rotating element is a sun gear of the second planetary gear mechanism, and the brake regulates a rotation of the first rotating element.

    摘要翻译: 一种混合动力车辆驱动单元,包括第一行星齿轮机构; 第二行星齿轮机构; 离合器 以及制动器,其中作为所述第一行星齿轮机构的太阳齿轮的第一太阳轮与第一旋转电机连接,作为所述第一行星齿轮机构的齿圈的第一齿圈与发动机连接, 并且作为第一行星齿轮机构的行星架的第一行星架与第二行星齿轮机构的第二旋转元件和驱动轮连接,第二行星齿轮机构的第一旋转元件与发动机连接, 并且第三旋转元件连接到第二旋转电机,第一旋转元件是第二行星齿轮机构的太阳齿轮,并且制动器调节第一旋转元件的旋转。

    DRIVING DEVICE FOR HYBRID VEHICLE
    6.
    发明申请
    DRIVING DEVICE FOR HYBRID VEHICLE 有权
    混合动力车辆的驱动装置

    公开(公告)号:US20150202953A1

    公开(公告)日:2015-07-23

    申请号:US14424231

    申请日:2012-08-28

    IPC分类号: B60K6/365 F16H57/04 B60K6/44

    摘要: A driving device for the hybrid vehicle includes a planetary gear mechanism; a first rotating machine coupled to a sun gear of the planetary gear mechanism; an engine coupled to a carrier of the planetary gear mechanism; a second rotating machine and a drive wheel that are coupled to a ring gear of the planetary gear mechanism; and a regulating mechanism that regulates rotation of the carrier, wherein the driving device has a first driving region that allows executing a dual-drive mode that causes running using the first rotating machine and the second rotating machine as power sources, and a second driving region that allows executing a lubrication running mode that causes the first rotating machine to rotate the engine so as to lubricate the planetary gear mechanism and causes running using the second rotating machine as a single power source.

    摘要翻译: 用于混合动力车辆的驱动装置包括行星齿轮机构; 联接到行星齿轮机构的太阳齿轮的第一旋转机械; 联接到所述行星齿轮机构的行星架的发动机; 第二旋转机械和驱动轮,其联接到所述行星齿轮机构的齿圈; 以及调节所述载体的旋转的调节机构,其中,所述驱动装置具有第一驱动区域,所述第一驱动区域允许执行使用所述第一旋转机器和所述第二旋转机器作为动力源的运行的双驱动模式,以及第二驱动区域 这允许执行润滑运行模式,其使得第一旋转机器使发动机旋转,以便润滑行星齿轮机构,并且使得使用第二旋转机器作为单个动力源运行。

    HYBRID VEHICLE DRIVING APPARATUS
    7.
    发明申请
    HYBRID VEHICLE DRIVING APPARATUS 审中-公开
    混合动力驱动装置

    公开(公告)号:US20140194238A1

    公开(公告)日:2014-07-10

    申请号:US14234726

    申请日:2011-07-27

    IPC分类号: B60K6/50

    摘要: A hybrid vehicle driving apparatus includes: a first planetary gear mechanism; a second planetary gear mechanism; a clutch that connects and disconnects a carrier of the first planetary gear mechanism to and from a carrier of the second planetary gear mechanism; and a brake that regulates the rotation of the carrier of the second planetary gear mechanism by engaging, in which a sun gear, the carrier, and a ring gear of the first planetary gear mechanism are respectively connected to a first rotating electric machine, an engine, and a driving wheel, and a sun gear and a ring gear of the second planetary gear mechanism are respectively connected to a second rotating electric machine and the driving wheel.

    摘要翻译: 一种混合动力车辆驱动装置,包括:第一行星齿轮机构; 第二行星齿轮机构; 离合器,其将所述第一行星齿轮机构的行星架与所述第二行星齿轮机构的行星架连接和断开; 以及制动器,其通过将第一行星齿轮机构的太阳齿轮,行星齿轮架和齿圈分别连接到第一旋转电机,发动机的引导来调节第二行星齿轮机构的行星架的旋转 第二行星齿轮机构的驱动轮,太阳齿轮和齿圈分别连接到第二旋转电机和驱动轮。

    Method for reading a CD having CD-text data
    8.
    发明授权
    Method for reading a CD having CD-text data 有权
    读取具有CD文本数据的CD的方法

    公开(公告)号:US06519676B1

    公开(公告)日:2003-02-11

    申请号:US09253744

    申请日:1999-02-22

    IPC分类号: G06F1200

    摘要: To determine whether a record medium loaded on a drive has character information in a management area of the record medium corresponding to data received from the drive and to obtain the character information when the record medium has the character information as the determined result. A system includes an optical disc drive and a host computer 53 connected through an interface 42, wherein the drive has a servo and signal processing portion 30, a system controller 41, and a CD-ROM signal processing portion 50. The servo and signal processing portion 30 reproduces data from a disc 21. The system controller 41 controls the entire operation of the drive. Return data is sent from the drive to the host computer 53 corresponding to a read table of contents (TOC) command received from the host computer 53. A code that represents the data length is contained in a header of the return data. With the code, it is determined whether or not the disc 21 is a CD-TEXT disc. When the, disc is a CD-TEXT disc as the determined result, the read TOC command is re-issued. Thus, CD-TEXT data is obtained.

    摘要翻译: 为了确定装载在驱动器上的记录介质是否具有与从驱动器接收到的数据对应的记录介质的管理区域中的字符信息,并且当记录介质具有作为确定结果的字符信息时获得字符信息。 系统包括通过接口42连接的光盘驱动器和主计算机53,其中驱动器具有伺服和信号处理部分30,系统控制器41和CD-ROM信号处理部分50.伺服和信号处理 部分30从盘21再现数据。系统控制器41控制驱动器的整个操作。 返回数据从驱动器发送到对应于从主计算机53接收的内容读取表(TOC)命令的主计算机53.表示数据长度的代码包含在返回数据的标题中。 利用代码,确定盘21是否是CD-TEXT盘。 当光盘是作为确定结果的CD-TEXT光盘时,重新发出读取的TOC命令。 因此,获得CD-TEXT数据。

    Method for calibrating discharge heat energy of optical fiber splicing device
    9.
    发明授权
    Method for calibrating discharge heat energy of optical fiber splicing device 有权
    校准光纤拼接装置放电热能的方法

    公开(公告)号:US06294760B1

    公开(公告)日:2001-09-25

    申请号:US09531181

    申请日:2000-03-21

    IPC分类号: G02B6255

    CPC分类号: G02B6/2553 G02B6/2551

    摘要: The object of the present invention is to provide a method of accurately calibrating discharge heat energy produced during fusion splicing of two optical fibers by heating the optical fibers arranged with the intentional fiber cladding axes offset; in order to achieve the object, the present invention provides a method of calibrating discharge heat energy used in the optical fiber fusion splicing device wherein a discharge heating energy is measured based on a change of the fiber cladding axes offset.

    摘要翻译: 本发明的目的是提供一种通过加热布置有有意纤维包覆轴偏移的光纤来精确地校准两个光纤的熔接期间产生的放电热能的方法; 为了实现该目的,本发明提供了一种校准在光纤熔接装置中使用的放电热能的方法,其中基于光纤包层轴偏移的变化来测量放电加热能量。

    Poly-amino acidic oligonucleotide-carrier
    10.
    发明授权
    Poly-amino acidic oligonucleotide-carrier 失效
    聚氨基酸酸性寡核苷酸载体

    公开(公告)号:US5912300A

    公开(公告)日:1999-06-15

    申请号:US619564

    申请日:1996-06-06

    摘要: The present invention provides a poly-amino acidic oligonucleotide-carrier comprising a poly-lysine:serine random copolymer.This carrier is bonded with oligonucleotide without causing precipitation, and smoothly releases the bonded oligonucleotide within cells. It is therefore useful as an in vivo transport carrier of an oligonucleotide drug against various genetic diseases and viral diseases such as AIDS. It also makes a great contribution to creation of various useful animals and plants by genetic engineering technique, including virus-resistant plants.

    摘要翻译: PCT No.PCT / JP94 / 01590 Sec。 371日期:1996年6月6日 102(e)日期1996年6月6日PCT 1994年9月28日PCT公布。 第WO95 / 09009号公报 日期1995年4月6日本发明提供了包含聚赖氨酸:丝氨酸无规共聚物的聚氨基酸酸性寡核苷酸载体。 该载体与寡核苷酸结合而不引起沉淀,并且在细胞内平滑释放键合的寡核苷酸。 因此,作为针对各种遗传疾病和病毒性疾病如AIDS的寡核苷酸药物的体内转运载体是有用的。 它还通过基因工程技术,包括抗病毒植物,为各种有用的动物和植物的创造做出了巨大的贡献。