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    Biomarker for diagnosis of liver disease
    1.
    发明授权
    Biomarker for diagnosis of liver disease 失效
    用于肝脏疾病诊断的生物标志物

    公开(公告)号：US08263347B2

    公开(公告)日：2012-09-11

    申请号：US12738684

    申请日：2008-10-20

    申请人： Hirohito Tsubouchi ,  Hirofumi Uto ,  Takeshi Okanoue ,  Yo-ichi Ishida ,  Yuko Sato ,  Masayuki Sudo

    发明人： Hirohito Tsubouchi ,  Hirofumi Uto ,  Takeshi Okanoue ,  Yo-ichi Ishida ,  Yuko Sato ,  Masayuki Sudo

    IPC分类号： G01N33/53

    CPC分类号： G01N33/6893 ,  G01N2333/8139 ,  G01N2800/085

    摘要： Disclosed are: a marker for the diagnosis of a liver disease, which can determine the disease in a simple manner; an antibody directed against the marker; a diagnostic agent; a diagnosis method; and a method for marker detection in blood or serum. Proteome analysis revealed that quantities of the full-length kininogen and three partial peptides thereof (sequence A: position-440 to position-456, sequence B: position-439 to position-456, and sequence C: position-438 to position-456) in sera of patients with non-alcoholic fatty liver disease are significantly different from those in sera of healthy individuals; and a diagnostic agent and a detecting method for the non-alcoholic fatty liver disease that can be conveniently used for medical examination are established. The use of a combination of a kininogen-based marker and a C4-based marker (the full length sequence or partial peptides thereof) enables identification of chronic hepatitis and an asymptomatic virus carrier, as well as non-alcoholic fatty liver disease.

    摘要翻译： 公开了一种用于诊断肝脏疾病的标志物，其可以以简单的方式确定疾病; 针对标记的抗体; 诊断剂; 诊断方法; 以及血液或血清中标记物检测的方法。 蛋白质组分析显示，全长激肽原及其三个部分肽（序列A：位置440至位置-456，序列B：位置-439至位置-456，序列C：位置-438至位置-456） ）与非酒精性脂肪性肝病患者的血清显着不同于健康人血清; 并建立了可以方便地用于体格检查的非酒精性脂肪肝疾病的诊断剂和检测方法。 使用基于激肽原的标记物和基于C4的标记物（其全长序列或其部分肽）的组合能够鉴定慢性肝炎和无症状病毒载体以及非酒精性脂肪肝疾病。

    BIOMARKER FOR DIAGNOSIS OF LIVER DISEASE
    2.
    发明申请
    BIOMARKER FOR DIAGNOSIS OF LIVER DISEASE 失效
    生物标志物诊断肝病

    公开(公告)号：US20110129859A1

    公开(公告)日：2011-06-02

    申请号：US12738684

    申请日：2008-10-20

    申请人： Hirohito Tsubouchi ,  Hirofumi Uto ,  Takeshi Okanoue ,  Yo-ichi Ishida ,  Yuko Sato ,  Masayuki Sudo

    发明人： Hirohito Tsubouchi ,  Hirofumi Uto ,  Takeshi Okanoue ,  Yo-ichi Ishida ,  Yuko Sato ,  Masayuki Sudo

    IPC分类号： G01N33/53 ,  C07K7/08 ,  C07K14/435 ,  C07K16/18

    CPC分类号： G01N33/6893 ,  G01N2333/8139 ,  G01N2800/085

    摘要： Disclosed are: a marker for the diagnosis of a liver disease, which can determine the disease in a simple manner; an antibody directed against the marker; a diagnostic agent; a diagnosis method; and a method for marker detection in blood or serum. Proteome analysis revealed that quantities of the full-length kininogen and three partial peptides thereof (sequence A: position-440 to position-456, sequence B: position-439 to position-456, and sequence C: position-438 to position-456) in sera of patients with non-alcoholic fatty liver disease are significantly different from those in sera of healthy individuals; and a diagnostic agent and a detecting method for the non-alcoholic fatty liver disease that can be conveniently used for medical examination are established. The use of a combination of a kininogen-based marker and a C4-based marker (the full length sequence or partial peptides thereof) enables identification of chronic hepatitis and an asymptomatic virus carrier, as well as non-alcoholic fatty liver disease.

    摘要翻译： 公开了：用于诊断肝脏疾病的标志物，其可以以简单的方式确定疾病; 针对标记的抗体; 诊断剂; 诊断方法; 以及血液或血清中标记物检测的方法。 蛋白质组分析显示，全长激肽原及其三个部分肽（序列A：位置440至位置-456，序列B：位置-439至位置-456，序列C：位置-438至位置-456） ）与非酒精性脂肪性肝病患者的血清显着不同于健康人血清; 建立了可以方便地用于体格检查的非酒精性脂肪肝疾病的诊断剂和检测方法。 使用基于激肽原的标记物和基于C4的标记物（其全长序列或其部分肽）的组合能够鉴定慢性肝炎和无症状病毒载体以及非酒精性脂肪肝疾病。

    Toner, and image forming method
    6.
    发明授权
    Toner, and image forming method 有权
    调色剂和成像方法

    公开(公告)号：US07297455B2

    公开(公告)日：2007-11-20

    申请号：US10900177

    申请日：2004-07-28

    申请人： Hiroyuki Fujikawa ,  Yuko Sato ,  Nobuyoshi Sugahara ,  Takayuki Itakura

    发明人： Hiroyuki Fujikawa ,  Yuko Sato ,  Nobuyoshi Sugahara ,  Takayuki Itakura

    IPC分类号： G03G13/00 ,  G03G9/00

    CPC分类号： G03G9/09708 ,  G03G9/08755 ,  G03G9/08782 ,  G03G9/09725 ,  G03G9/09783

    摘要： A toner is composed primarily of toner particles containing at least a binder resin, a colorant and a wax, and inorganic fine particles. The binder resin is one which has at least a polyester unit and is synthesized by using as a catalyst one or more compounds selected from titanium chelate compounds each having a specific structure and hydrates of the titanium chelate compounds. The toner has superior fixing performance and high-temperature anti-offset properties and is superior in charge stability even when used for a long time.

    摘要翻译： 调色剂主要由至少含有粘合剂树脂，着色剂和蜡的调色剂颗粒和无机细颗粒组成。 粘合剂树脂是至少具有聚酯单元的粘合剂树脂，并且通过使用一种或多种选自具有特定结构的钛螯合物和钛螯合物的水合物的化合物作为催化剂来合成。 该调色剂具有优异的定影性能和高温抗污损性，并且即使长时间使用也具有优异的电荷稳定性。

    Cyan toner and method for forming an image
    7.
    发明授权
    Cyan toner and method for forming an image 有权
    青色调色剂和形成图像的方法

    公开(公告)号：US07138213B2

    公开(公告)日：2006-11-21

    申请号：US10793965

    申请日：2004-03-05

    申请人： Takayuki Itakura ,  Yoshinobu Baba ,  Yuko Sato ,  Nobuyoshi Sugahara ,  Kazuo Terauchi ,  Takaaki Kotaki ,  Hirohide Tanikawa

    发明人： Takayuki Itakura ,  Yoshinobu Baba ,  Yuko Sato ,  Nobuyoshi Sugahara ,  Kazuo Terauchi ,  Takaaki Kotaki ,  Hirohide Tanikawa

    IPC分类号： G03G9/09 ,  G03G15/01

    CPC分类号： G03G9/08786 ,  G03G9/0821 ,  G03G9/08782 ,  G03G9/09

    摘要： The present invention provides a cyan toner including: one or plural heat-absorption peaks in a temperature range of 30 to 200° C. in a heat-absorption curve obtained by using a differential scanning calorimeter; a maximal value of a maximum heat-absorption peak temperature in the range of 65 to 150° C.; and a reflectance of 45 to 80% at a wavelength of 500 nm, a reflectance of 5 to 30% at a wavelength of 600 nm, and a brightness L* of 45 to 75, when measured in a powder form by spectroscopic analysis. The present invention thus provides a cyan toner capable of forming an image with reduced graininess and roughness from a low-density region to a high-density region and ensured a sufficient fixing temperature region, and a method for forming an image using the cyan toner.

    摘要翻译： 本发明提供了一种青色调色剂，其包括：在通过使用差示扫描量热计获得的热吸收曲线中，在30至200℃的温度范围内的一个或多个吸热峰; 最大吸热峰温度的最大值在65〜150℃的范围内。 当波长为500nm时的反射率为45〜80％，波长600nm的反射率为5〜30％，通过光谱分析以粉末形式测定时的亮度L *为45〜75。 因此，本发明提供了能够形成从低密度区域到高密度区域具有降低的颗粒度和粗糙度的图像的青色调色剂，并确保了足够的定影温度区域，以及使用青色调色剂形成图像的方法。

    Apparatus, method, and program product for supporting programming
    8.
    发明授权
    Apparatus, method, and program product for supporting programming 失效
    用于支持编程的装置，方法和程序产品

    公开(公告)号：US07134114B2

    公开(公告)日：2006-11-07

    申请号：US10438281

    申请日：2003-05-14

    申请人： Yuko Sato ,  Tomotaka Murakami ,  Akio Hiruma

    发明人： Yuko Sato ,  Tomotaka Murakami ,  Akio Hiruma

    IPC分类号： G06F9/44

    CPC分类号： G06F8/34

    摘要： According to an embodiment, a computer system displays, on a display, a GUI dialog box that prompts an operator to set the identification name and thread type of a source file that describes source code of a thread. When the identification name and thread type of the source file are set via the GUI dialog box, the computer system acquires a source code template corresponding to that thread type, and reflects the identification name set via the GUI dialog box in that source code template. The computer system generates a source file with the identification name set via the GUI dialog box in the basis of the source code template. The computer system stores the identification name and thread type set via the GUI dialog box in a definition file as thread definition information of the source file set with the identification name.

    摘要翻译： 根据实施例，计算机系统在显示器上显示GUI对话框，其提示操作者设置描述线程的源代码的源文件的标识名称和线程类型。 当通过GUI对话框设置源文件的识别名称和线程类型时，计算机系统将获取与该线程类型相对应的源代码模板，并通过该对象框中的GUI代码模板反映设置的标识名称。 计算机系统根据源代码模板生成通过GUI对话框设置的识别名称的源文件。 计算机系统将通过GUI对话框设置的识别名称和线程类型存储在定义文件中，作为具有识别名称的源文件的线程定义信息。

    Toner and method for forming image
    9.
    发明申请
    Toner and method for forming image 有权
    调色剂及形成图像的方法

    公开(公告)号：US20050014079A1

    公开(公告)日：2005-01-20

    申请号：US10890165

    申请日：2004-07-14

    申请人： Takayuki Itakura ,  Yuko Sato ,  Hiroyuki Fujikawa ,  Nobuyoshi Sugahara ,  Hirohide Tanikawa

    发明人： Takayuki Itakura ,  Yuko Sato ,  Hiroyuki Fujikawa ,  Nobuyoshi Sugahara ,  Hirohide Tanikawa

    IPC分类号： G03G9/08 ,  G03G9/087 ,  G03G9/09 ,  G03G9/097 ,  G03G15/01

    CPC分类号： G03G9/08795 ,  G03G9/0821 ,  G03G9/08742 ,  G03G9/08755 ,  G03G9/08782 ,  G03G9/08786 ,  G03G9/08797 ,  G03G9/092 ,  G03G9/0926

    摘要： A magenta toner is provided which contains at least a binder resin, a colorant, and a wax, in which a maximum heat-absorption peak temperature as measured using a differential scanning calorimeter, a reflectance at a predetermined wavelength when measured in a powder state by spectroscopic analysis, and lightness when measured in a powder form are in specific ranges. A full-color image is formed using the magenta toner as a pale magenta toner in combination with a deep magenta toner. According to the present invention, it becomes possible to form a vivid image which has reduced graininess and roughness from a low-density region to a high-density region, ensures a sufficient fixing temperature region, has a color reproduction range wider that the conventional one, and has high transparency on an OHP sheet.

    摘要翻译： 提供品红色调色剂，其至少含有粘合剂树脂，着色剂和蜡，其中使用差示扫描量热计测量的最大吸热峰值温度，当以粉末状态测量时以预定波长的反射率通过 光谱分析和粉末状测定时的亮度均在特定范围内。 使用洋红色调色剂作为浅洋红色调色剂与深品红色调色剂组合形成全色图像。 根据本发明，可以形成从低密度区域到高密度区域具有降低的颗粒性和粗糙度的生动的图像，确保足够的定影温度区域，具有比现有技术更宽的色彩再现范围 ，并且在OHP片材上具有高透明度。

    Packaged piezoelectric transformer unit
    10.
    发明授权
    Packaged piezoelectric transformer unit 失效
    封装压电变压器单元

    公开(公告)号：US5747916A

    公开(公告)日：1998-05-05

    申请号：US608060

    申请日：1996-02-28

    申请人： Mitsuhiro Sugimoto ,  Yuji Kondo ,  Koichi Zama ,  Yuko Sato

    发明人： Mitsuhiro Sugimoto ,  Yuji Kondo ,  Koichi Zama ,  Yuko Sato

    IPC分类号： H01L41/053 ,  H01L41/107 ,  H03H9/10

    CPC分类号： H01L41/107 ,  H01L41/053

    摘要： In a piezoelectric transformer unit which transforms an input voltage into an output voltage and which includes a piezoelectric transformer element driven by high electric power, a package is provided to accommodate the piezoelectric transformer element therein. Electrodes are attached to nodes of the piezoelectric transformer element and supported by each pair of input and output conductive leads which are operable as leaf springs and which are extended through the package. Contact portions of the conductive leads may provide point contacts, area contacts, and/or line contacts.

    摘要翻译： 在将输入电压变换为输出电压并且包括由高功率驱动的压电变压器元件的压电变压器单元中，提供封装以在其中容纳压电变压器元件。 电极附着在压电变压器元件的节点上，由每对输入和输出导电引线支撑，导电导线可作为板簧进行操作，并延伸穿过封装。 导电引线的接触部分可以提供点触点，区域触点和/或线触点。