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公开(公告)号：US08229531B2
公开(公告)日：2012-07-24
申请号：US11914701
申请日：2006-02-13
IPC分类号： A61B5/1455
CPC分类号： A61B5/0059 , A61B5/6814 , A61B2562/0233 , A61B2562/046
摘要： There is provided an optical bioinstrumentation device, with which measurement data reflect more correctly the information inside the living body with less noise even the subject moves when the information inside the living body is measured by using the light.In the present invention, the means for fixing the part other than the tips of the optical fibers for irradiation and detection on the fixing member which is to fix the tips of the optical fiber for irradiation and detection on the subject, or, the means for fixing the optical fiber is fixed on the fixing member which is to fix the end of the optical fiber on the subject, or the means for fixing the optical fiber at two or more positions on the subject.
摘要翻译： 提供了一种光学生物仪器装置，通过使用光来测量生物体内部的信息，即使被检体移动，测量数据也能更准确地反映生物体内部的信息，噪音较小。 在本发明中，将用于照射和检测的光纤的末端以外的部分固定在固定部件上的装置，该固定部件用于将用于照射和检测的光纤的前端固定在被检体上， 固定光纤被固定在将光纤端部固定在被摄体上的固定部件上，或将光纤固定在被检体上的两个以上位置的装置。
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公开(公告)号：US20090088616A1
公开(公告)日：2009-04-02
申请号：US11914701
申请日：2006-02-13
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/6814 , A61B2562/0233 , A61B2562/046
摘要： There is provided an optical bioinstrumentation device, with which measurement data reflect more correctly the information inside the living body with less noise even the subject moves when the information inside the living body is measured by using the light.In the present invention, the means for fixing the part other than the tips of the optical fibers for irradiation and detection on the fixing member which is to fix the tips of the optical fiber for irradiation and detection on the subject, or, the means for fixing the optical fiber is fixed on the fixing member which is to fix the end of the optical fiber on the subject, or the means for fixing the optical fiber at two or more positions on the subject.
摘要翻译： 提供了一种光学生物仪器装置，通过使用光来测量生物体内部的信息，即使被检体移动，测量数据也能更准确地反映生物体内部的信息，噪音较小。 在本发明中，将用于照射和检测的光纤的末端以外的部分固定在固定部件上的装置，该固定部件用于将用于照射和检测的光纤的前端固定在被检体上， 固定光纤被固定在将光纤端部固定在被摄体上的固定部件上，或将光纤固定在被检体上的两个以上位置的装置。
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3.发明授权公开(公告)号：US09198624B2
公开(公告)日：2015-12-01
申请号：US13806790
申请日：2011-07-06
申请人： Tsukasa Funane , Hirokazu Atsumori , Takusige Katura , Masashi Kiguchi , Tsuyoshi Takatera , Michiyuki Fujiwara
发明人： Tsukasa Funane , Hirokazu Atsumori , Takusige Katura , Masashi Kiguchi , Tsuyoshi Takatera , Michiyuki Fujiwara
IPC分类号： A61B6/00 , A61B5/00 , G01N21/359 , G01N21/49
CPC分类号： A61B6/00 , A61B5/0042 , A61B5/0075 , A61B5/6814 , G01N21/359 , G01N21/49
摘要： The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.
摘要翻译： 本发明能够分离/去除包含在近红外光谱（NIRS）信号中的皮肤血流的影响并提取脑或脑皮层起始信号。 此外，鉴于个体之间的差异，本发明能够多功能地分离脑起源和皮肤起始信号。 一种生物测光装置，其中光发射器和光接收器以这样的方式定位，使得可以在多个源 - 检测器（SD）距离处进行测量，并且由各个光接收器接收的光可以通过灰质，从而 分离脑起始信号和皮肤起始信号。 对各个测量点获得的数据进行单独分量分析（ICA）。 然后，使用每个分离的组分的加权值的SD距离相关性来确定每个单独组分是否来自大脑或皮肤。
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4.发明申请公开(公告)号：US20130102907A1
公开(公告)日：2013-04-25
申请号：US13806790
申请日：2011-07-06
申请人： Tsukasa Funane , Hirokazu Atsumori , Takusige Katura , Masashi Kiguchi , Tsuyoshi Takatera , Michiyuki Fujiwara
发明人： Tsukasa Funane , Hirokazu Atsumori , Takusige Katura , Masashi Kiguchi , Tsuyoshi Takatera , Michiyuki Fujiwara
IPC分类号： A61B6/00
CPC分类号： A61B6/00 , A61B5/0042 , A61B5/0075 , A61B5/6814 , G01N21/359 , G01N21/49
摘要： The present invention is capable of separating/removing the influence of skin blood flow contained in near infrared spectroscopy (NIRS) signals and extracting a brain- or brain cortex-origin signal. Moreover, the present invention enables versatile separation of brain-origin and skin-origin signals in view of differences among individuals. A biological photometric device, wherein light transmitters and light receivers are located in such a manner that measurement can be conducted at a plurality of source-detector (SD) distances and light received by the individual light-receivers can pass through the gray matter to thereby separate a brain-origin signal and a skin-origin signal. Individual component analysis (ICA) is conducted on data obtained at the individual measurement points. Then, it is determined whether each individual component originates in the brain or in the skin with the use of the SD distance-dependency of the weighted value of each of the separated components.
摘要翻译： 本发明能够分离/去除包含在近红外光谱（NIRS）信号中的皮肤血流的影响并提取脑或脑皮层起始信号。 此外，鉴于个体之间的差异，本发明能够多功能地分离脑起源和皮肤起始信号。 一种生物测光装置，其中光发射器和光接收器以这样的方式定位，使得可以在多个源 - 检测器（SD）距离处进行测量，并且由各个光接收器接收的光可以通过灰质，从而 分离脑起始信号和皮肤起始信号。 对各个测量点获得的数据进行单独分量分析（ICA）。 然后，使用每个分离的组分的加权值的SD距离相关性来确定每个单独组分是否来自大脑或皮肤。
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公开(公告)号：US09706955B2
公开(公告)日：2017-07-18
申请号：US14408644
申请日：2012-06-21
申请人： Hirokazu Atsumori , Masashi Kiguchi
发明人： Hirokazu Atsumori , Masashi Kiguchi
IPC分类号： A61B5/1455 , A61B5/00 , A61B5/145 , G06N5/04 , A61B5/16
CPC分类号： A61B5/14553 , A61B5/14546 , A61B5/14552 , A61B5/165 , A61B5/486 , A61B5/7225 , A61B5/7246 , A61B5/7278 , A61B5/742 , A61B5/743 , A61B5/7435 , A61B5/7475 , A61B2505/09 , A61B2560/0475 , A61B2562/0238 , G06N5/04
摘要： Provided is a biological state assessment device for assessing biological state, such as mood or emotions, using non-invasive biophotonic measurement technology. The present invention includes a light irradiation unit (1041), a light-receiving unit (1061), and an inputting means (112). A subject (800) is presented with a plurality of different problems (first problem, second problem), and a biological signal in the interior of the subject is calculated from the intensity of light received by the light-receiving unit (1061). Subjective information about the subject is accepted by the inputting means (112). The difference is calculated between the subjective information and the relative value of the biological signal of the measurement point for the first problem and the biological signal of the measurement point for the second problem, and the result is displayed.
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6.发明申请BIOLOGICAL OPTICAL MEASUREMENT DEVICE, STIMULUS PRESENTATION METHOD, AND STIMULUS PRESENTATION PROGRAM 审中-公开生物光学测量设备，STIMULUS演示方法和STIMULUS演示程序公开(公告)号：US20140107439A1
公开(公告)日：2014-04-17
申请号：US14117154
申请日：2012-06-15
申请人： Hirokazu Atsumori , Hiroki Sato , Masashi Kiguchi
发明人： Hirokazu Atsumori , Hiroki Sato , Masashi Kiguchi
IPC分类号： A61B5/16 , A61B5/1455
CPC分类号： A61B5/165 , A61B5/14551
摘要： Disclosed is a device using a biological optical measurement technology to evaluate mood states in daily life of an examinee by presenting a first task once or a plurality of times and then presents a second task a plurality of times, calculating a hemoglobin signal of a predetermined measurement point for the first task and a hemoglobin signal of a predetermined measurement point for the second task, and calculating quantitative values using the obtained hemoglobin signals.
摘要翻译： 公开了一种使用生物光学测量技术的装置，通过呈现第一任务一次或多次来评估受试者的日常生活中的情绪状态，然后多次呈现第二任务，计算预定测量的血红蛋白信号 指定第一任务和第二任务的预定测量点的血红蛋白信号，以及使用获得的血红蛋白信号计算定量值。
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公开(公告)号：US08244324B2
公开(公告)日：2012-08-14
申请号：US11941296
申请日：2007-11-16
IPC分类号： A61B5/1455
CPC分类号： G01N21/253 , A61B5/0059 , A61B5/7228 , A61B2560/0252
摘要： An optical measurement instrument for a living body having an optical fiber removed, which is composed so as to transmit a driving signal for the light source to a plurality of an irradiation parts, as well as to convert a transmitted and received signal, between a processing and control unit and the probe unit, to a row of serial digital signals, by having one driving device for light source and one multiplexer, inside the probe unit.
摘要翻译： 一种用于生物体的光学测量仪器，其具有除去的光纤，该光学测量仪器被构造成将光源的驱动信号传输到多个照射部分，以及在发送和接收的信号之间转换处理 以及控制单元和探针单元，通过在探针单元内部具有用于光源的一个驱动装置和一个多路复用器连接到一排串行数字信号。
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公开(公告)号：US20090054789A1
公开(公告)日：2009-02-26
申请号：US12219259
申请日：2008-07-18
IPC分类号： A61B5/00
CPC分类号： A61B5/0059 , A61B5/1455 , A61B5/6814 , A61B2562/0233 , A61B2562/046
摘要： A head-coupled holder for living body optical measurement that securely brings a light irradiation module and a light detection module in close contact with a scalp, and gives the person to be examined no excessive pressure feeling. Each of the light irradiation module and the light detection module includes a contactor having a contact portion that comes in contact with a scalp of the person to be examined at a leading end thereof, and exposes a leading end of a light guide to the contact portion to form the light guide, and a package having a lower portion to which the contactor is attached. The contactor is fixed to the lower portion of the package through an elastic body, and the package is fixed to an inner upper wall of the insertion hole with a series structure of the elastic body and the viscoelastic body.
摘要翻译： 一种用于生物体光学测量的头部联接保持器，其牢固地带有与头皮紧密接触的光照射模块和光检测模块，并且给予被检查者没有过大的压力感。 光照射模块和光检测模块中的每一个包括具有接触部分的接触器，接触部分在其前端与被检查者的头皮接触，并且将导光体的前端暴露于接触部分 以形成光导，以及具有接合器所附接的下部的封装。 接触器通过弹性体固定到包装的下部，并且包装件以弹性体和粘弹性体的串联结构固定到插入孔的内上壁。
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公开(公告)号：US08750951B2
公开(公告)日：2014-06-10
申请号：US12216360
申请日：2008-07-02
IPC分类号： A61B5/00
CPC分类号： A61B5/1455 , A61B5/14553
摘要： To make the peak value of the driving current of light source smaller than the conventional one and to make the peak value of the light receiving level of light-sensitive elements smaller than the conventional one in order to save power consumption of the device and to improve the precision of measurement, codes of which the bits of the Hadamard codes are shifted by the same bit for each code series having the same bit cycle, or codes of which the bits of a PN code are shifted are used as different codes.
摘要翻译： 为了使光源的驱动电流的峰值小于常规的峰值，并且使感光元件的光接收电平的峰值比常规的更小，以节省器件的功耗并改善 对于具有相同比特周期的每个码序列，或者其中PN码的比特被移位的码的Hadamard码的比特被移位了同一比特的码的精度被用作不同的码。
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公开(公告)号：US20080183056A1
公开(公告)日：2008-07-31
申请号：US11941296
申请日：2007-11-16
IPC分类号： A61B5/00
CPC分类号： G01N21/253 , A61B5/0059 , A61B5/7228 , A61B2560/0252
摘要： An optical measurement instrument for a living body having an optical fiber removed, which is composed so as to transmit a driving signal for the light source to a plurality of an irradiation parts, as well as to convert a transmitted and received signal, between a processing and control unit and the probe unit, to a row of serial digital signals, by having one driving device for light source and one multiplexer, inside the probe unit.
摘要翻译： 一种用于生物体的光学测量仪器，其具有除去的光纤，该光学测量仪器被构造成将光源的驱动信号传输到多个照射部分，以及在发送和接收的信号之间转换处理 以及控制单元和探针单元，通过在探针单元内部具有用于光源的一个驱动装置和一个多路复用器连接到一排串行数字信号。
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