公开(公告)号：USRE40573E1

公开(公告)日：2008-11-18

申请号：US11368335

申请日：2006-03-02

申请人： Takato Ogiwara ,  Kenji Sano ,  Naganori Koshimizu ,  Hiromi Ando

发明人： Takato Ogiwara ,  Kenji Sano ,  Naganori Koshimizu ,  Hiromi Ando

IPC分类号： B60T11/224

CPC分类号： B60T11/224 ,  B60T11/26

摘要： A master cylinder of the invention supplies a brake fluid from a large diameter pressurizing chamber 56 to a small diameter hydraulic chamber 49 by opening a reverse flow checking opening and closing portion 61 by sliding movement of a stepped piston 16 forwardly, that is, fast fill and when the hydraulic pressure of the large diameter pressurizing chamber 56 rises, a control valve 86 escapes the hydraulic pressure of the large diameter pressurizing chamber 56 to a reservoir 12 to gradually lower in accordance with rise of the hydraulic pressure of the small diameter hydraulic chamber 49, thereby capable of reducing a strange feeling in a pedal feeling caused by sudden pressure release of the large diameter pressurizing chamber 56.

摘要翻译： 本发明的主缸通过向前倾斜阶梯式活塞16的滑动打开反向流动检查开闭部61来将制动液从大直径加压室56供给到小直径液压室49，即快速填充 并且当大直径加压室56的液压上升时，控制阀86将大直径加压室56的液压从储存器12排出，以便随着小直径液压室的液压升高逐渐降低 从而能够减小由大直径加压室56的突然的压力释放引起的踏板感觉的奇怪的感觉。

公开(公告)号：US06272858B1

公开(公告)日：2001-08-14

申请号：US09396421

申请日：1999-09-15

申请人： Eiichi Takano ,  Takato Ogiwara ,  Hiromi Ando

发明人： Eiichi Takano ,  Takato Ogiwara ,  Hiromi Ando

IPC分类号： F15B708

CPC分类号： F16D25/088 ,  B60T11/20 ,  B60T11/232 ,  B60T11/236

摘要： A master cylinder includes a cylinder, a piston slidably provided in the cylinder, an annular cup seal held on an inner circumferential surface of the cylinder, and a relief port formed in the piston. The piston and the cylinder define a pressure chamber for generating fluid pressure in front of the piston, and the cylinder and an outer circumferential surface of the piston define a fluid supply chamber which communicates with a reservoir. The cup seal is adapted to slide against the outer circumferential surface of the piston to separate the fluid supply chamber from the pressure chamber. The relief port provides communication between the pressure chamber and the fluid supply chamber. A control taper surface is formed on the outer circumferential surface of the piston rearwardly from the relief port. The control taper surface is tapered toward the front of the piston and is capable of abutting against an inner circumferential surface of the cup seal.

摘要翻译： 主缸包括缸体，可滑动地设置在缸体中的活塞，保持在缸体的内圆周表面上的环形杯密封件和形成在活塞中的卸载口。 活塞和气缸限定了用于在活塞前方产生流体压力的压力室，并且气缸和活塞的外圆周表面限定了与储存器连通的流体供应室。 杯形密封件适于相对于活塞的外周表面滑动以将流体供应室与压力室分离。 释放口提供压力室和流体供应室之间的连通。 控制锥面形成在活塞的外周面上，从减压口向后方。 控制锥形表面朝向活塞的前部逐渐变细，并且能够抵靠杯形密封件的内周表面。

公开(公告)号：US5553530A

公开(公告)日：1996-09-10

申请号：US447049

申请日：1995-05-22

申请人： Mitsuhiro Endo ,  Kiyoshi Shirahata ,  Hiromi Ando

发明人： Mitsuhiro Endo ,  Kiyoshi Shirahata ,  Hiromi Ando

IPC分类号： B60T13/52 ,  B60T13/56 ,  B60T13/57

CPC分类号： B60T13/57

摘要： A plunger moved with an input shaft is movably fitted in an axial bore of a valve body made of resin, and a valve mechanism selectively establishes and cuts off communication in a negative pressure passage and an atmosphere passage formed in the valve body according to the movement of the plunger. Also, a pair of radial holes formed to have a circular cross section are provided in the valve body by drilling work, and a plate type stop key formed in a fork shape having two claw branches is mounted by loosely inserting the branches in the radial holes. The stop key limits a movement range of the plunger. Also, a guide portion is formed on an outer circumference of the valve body to guide side surfaces of the stop key. The movement of the stop key is restricted by the guide portion and a step formed in the axial bore of the valve body. Therefore, a smooth operation of the pneumatic booster can be guaranteed.

摘要翻译： 用输入轴移动的柱塞可移动地装配在由树脂制成的阀体的轴向孔中，并且阀机构根据运动选择性地建立和切断在负压通道和形成在阀体中的气氛通道中的连通 的柱塞。 另外，通过钻孔工作在阀体上设置一对形成为圆形横截面的径向孔，并且通过将分支松动地插入到径向孔中来安装形成为具有两个爪分支的叉状的板式止动键 。 停止键限制柱塞的移动范围。 而且，引导部分形成在阀体的外周上，以引导停止键的侧表面。 止动键的移动受到引导部分的限制，并且形成在阀体的轴向孔中的台阶。 因此，可以保证气动助力器的平稳运行。

公开(公告)号：US4632208A

公开(公告)日：1986-12-30

申请号：US683196

申请日：1984-12-18

申请人： Toshio Takayama ,  Hiromi Ando ,  Yukio Matsumoto

发明人： Toshio Takayama ,  Hiromi Ando ,  Yukio Matsumoto

IPC分类号： B60T7/12 ,  B60T13/563 ,  B60T13/57

CPC分类号： B60T13/563 ,  B60T13/57 ,  B60T7/12

摘要： A vehicle braking system for use in a vehicle such as an automobile, and including at least one wheel brake, a brake pedal, and a brake applying device such as a master cylinder or a pneumatic booster which is connected to the brake pedal for applying hydraulic pressure on the wheel brake in response to actuation of the brake pedal. A selector valve is connected to the brake applying device and acts, when actuated, to maintain hydraulic pressure in the wheel brake irrespective to the release of the brake pedal. Further, there are provided at least one sensor such as a sensor sensing the running speed of the vehicle, a sensor sensing the actuation of a gas pedal, a sensor sensing whether a seat belt in the driver's seat is fitted on or not and the like, and a controller connected to the sensor for actuating the selector valve in response to a predetermined operational condition of the vehicle.

摘要翻译： 一种用于诸如汽车的车辆的车辆制动系统，并且包括至少一个车轮制动器，制动踏板和诸如主缸或气动助力器的制动施加装置，其连接到制动踏板以施加液压 响应于制动踏板的致动，车轮制动器上的压力。 选择阀连接到制动施加装置，并且在致动时作用，以保持车轮制动器中的液压，而与制动踏板的释放无关。 此外，提供了至少一个传感器，例如感测车辆的行驶速度的传感器，感测加速踏板的致动的传感器，感测驾驶员座椅中的座椅安全带是否安装的传感器等 以及连接到所述传感器的控制器，用于响应于所述车辆的预定操作条件来致动所述选择阀。

公开(公告)号：US4259893A

公开(公告)日：1981-04-07

申请号：US961022

申请日：1978-11-15

申请人： Hiromi Ando ,  Kiyoshi Tateoka ,  Yoshihiro Hayashida

发明人： Hiromi Ando ,  Kiyoshi Tateoka ,  Yoshihiro Hayashida

IPC分类号： B60T13/573 ,  B60T13/577 ,  F15B9/10

CPC分类号： B60T13/577

摘要： A fluid pressure operated servomotor such as a vacuum booster including a power piston having a differential pressure acting thereacross, an input rod for actuating a valve mechanism mounted in the power piston, a reaction lever disposed between the power piston and an output rod for transmitting a force to the output rod and transmitting a reaction force to the input rod. A return spring for urging the power piston in the return direction acts through the reaction lever on the power piston, whereby the reaction force is not transmitted to the input rod until the force transmitted to the output rod exceeds a predetermined value.

摘要翻译： 一种流体压力操作的伺服电动机，例如包括具有作用在其上的压差的动力活塞的真空助力器，用于致动安装在动力活塞中的阀机构的输入杆，设置在动力活塞和输出杆之间的反作用杆， 向输出杆施加力并将反作用力传递到输入杆。 用于在返回方向上推动动力活塞的复位弹簧作用在动力活塞上的反作用杆上，由此反作用力不会传递到输入杆，直到传递到输出杆的力超过预定值。

公开(公告)号：US4085656A

公开(公告)日：1978-04-25

申请号：US704621

申请日：1976-07-12

申请人： Hiromi Ando

发明人： Hiromi Ando

IPC分类号： B60T13/57 ,  F15B9/10

CPC分类号： B60T13/57 ,  Y10T137/86919

摘要： A vacuum booster has a housing the interior of which is divided into a vacuum chamber and a pressure chamber, a plunger connected to an input rod and fitted slidably in a cylinder portion of a valve body, and valve seats defined respectively on adjacent ends of the plunger and the cylinder portion to cooperate with a seating surface of a valve member for controlling respectively the communication between the pressure chamber and the atmosphere and between the two chambers. A surface portion of the seating surface of the valve member with which at least one of the valve seats engages is a curved rotational surface.

摘要翻译： 真空助力器具有壳体，其内部被分成真空室和压力室，连接到输入杆并且可滑动地装配在阀体的气缸部分中的柱塞以及分别限定在阀体的相邻端部上的阀座 柱塞和气缸部分，以与阀构件的就座表面配合，以分别控制压力室和大气之间以及两个室之间的连通。 阀构件的座表面的至少一个阀座与其接合的表面部分是弯曲的旋转表面。

公开(公告)号：US07605272B2

公开(公告)日：2009-10-20

申请号：US11814753

申请日：2006-01-27

申请人： Yutaka Kanda ,  Hiromi Ando ,  Keiko Kawashima ,  Takamasa Sugita ,  Masayo Suzuki ,  Hisashi Tagaya ,  Tomoyuki Nakazato ,  Yoshinori Yamashita ,  Takeshi Takahashi ,  Shinji Nara ,  Hiroaki Nakamura

发明人： Yutaka Kanda ,  Hiromi Ando ,  Keiko Kawashima ,  Takamasa Sugita ,  Masayo Suzuki ,  Hisashi Tagaya ,  Tomoyuki Nakazato ,  Yoshinori Yamashita ,  Takeshi Takahashi ,  Shinji Nara ,  Hiroaki Nakamura

IPC分类号： C07D231/56 ,  C07D211/06 ,  C07D413/10 ,  C07D403/10 ,  A61K31/416 ,  A61K31/4439 ,  A61K31/496 ,  A61K31/5355 ,  A61K31/5377

CPC分类号： C07D231/56 ,  C07D401/12 ,  C07D405/12 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D491/10 ,  C07D495/04

摘要： The present invention provides a type I insulin-like growth factor receptor (IGF-1R) inhibitor comprising, as an active ingredient, an indazole derivative represented by Formula (I): {wherein R1 represents —NR4R5 [wherein R4 represents a hydrogen atom or the like, R5 represents substituted or unsubstituted lower alkyl, —C(═O)R6 (wherein R6 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl or the like), or the like], or the like, and R2 and R3 may be the same or different and each represents a hydrogen atom, hydroxy, substituted or unsubstituted lower alkoxy, or the like} or a pharmaceutically acceptable salt thereof, and the like.

摘要翻译： 本发明提供一种I型胰岛素样生长因子受体（IGF-1R）抑制剂，其包含作为活性成分的由式（I）表示的吲唑衍生物：其中R 1表示-NR 4 R 5 [其中R 4表示氢原子或 R 5表示取代或未取代的低级烷基，-C（-O）R 6（其中R 6表示取代或未取代的低级烷基，取代或未取代的芳基等），R 2和R 3可以相同 或不同的，并且各自表示氢原子，羟基，取代或未取代的低级烷氧基等}或其药学上可接受的盐等。

公开(公告)号：US20070117856A1

公开(公告)日：2007-05-24

申请号：US10548475

申请日：2004-07-30

申请人： Yoshihisa Ohta ,  Fumihiko Kanai ,  Shinji Nara ,  Yutaka Kanda ,  Hiroshi Umehara ,  Yukimasa Shiotsu ,  Tomoki Naoe ,  Hitoshi Kiyoi ,  Keiko Kawashima ,  Hiromi Ando ,  Motoki Miyama

发明人： Yoshihisa Ohta ,  Fumihiko Kanai ,  Shinji Nara ,  Yutaka Kanda ,  Hiroshi Umehara ,  Yukimasa Shiotsu ,  Tomoki Naoe ,  Hitoshi Kiyoi ,  Keiko Kawashima ,  Hiromi Ando ,  Motoki Miyama

IPC分类号： A61K31/416 ,  C07D231/56

CPC分类号： C07D231/56

摘要： The present invention provides a compound represented by Formula (I): [wherein R1 represents CONR1aR1b (wherein R1a and R1b may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, substituted or unsubstituted ararkyl or a substituted or unsubstituted heterocyclic group, or R1a and R1b are combined together with the adjacent nitrogen atom thereto to form a substituted or unsubstituted heterocyclic group) or the like, R2 represents a hydrogen atom, CONR2aR2b (wherein R2a and R2b may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, substituted or unsubstituted ararkyl or a substituted or unsubstituted heterocyclic group, or R2a and R2b are combined together with the adjacent nitrogen atom thereto to form a substituted or unsubstituted heterocyclic group), NR2cR2d (wherein R2c and R2d may be the same or different and each represents a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkanoyl, substituted or unsubstituted aroyl, substituted or unsubstituted heteroaroyl, substituted or unsubstituted ararkyl, substituted or unsubstituted lower alkylsulfonyl or substituted or unsubstituted lower arylsulfonyl) or the like].

摘要翻译： 本发明提供由式（I）表示的化合物：[其中R 1表示CONR 1a 1b 1b（其中R 1a） R 1b和R 1b可以相同或不同，各自表示氢原子，取代或未取代的低级烷基，取代或未取代的芳基，取代或未取代的芳烷基或取代或未取代的杂环基， 或R 1a和R 1b与相邻的氮原子一起形成取代或未取代的杂环基）等，R 2 O， >表示氢原子，其中R 2a，R 2b和R 2b可以相同或不同， 各自表示氢原子，取代或未取代的低级烷基，取代或未取代的芳基，取代或未取代的芳烷基或取代或未取代的杂环基，或R 2b和R 2b >与t结合在一起 它与氮原子相邻以形成取代或未取代的杂环基），NR 2c R 2d（其中R 2c和R 2d） 取代或未取代的低级烷酰基，取代或未取代的芳酰基，取代或未取代的杂芳酰基，取代或未取代的芳烷基，取代或未取代的低级烷基磺酰基或 取代或未取代的低级芳基磺酰基等）。

公开(公告)号：US06698202B2

公开(公告)日：2004-03-02

申请号：US10084261

申请日：2002-02-26

申请人： Takato Ogiwara ,  Kenji Sano ,  Naganori Koshimizu ,  Hiromi Ando

发明人： Takato Ogiwara ,  Kenji Sano ,  Naganori Koshimizu ,  Hiromi Ando

IPC分类号： B60T11224

CPC分类号： B60T11/224 ,  B60T11/26

摘要： A master cylinder of the invention supplies a brake fluid from a large diameter pressurizing chamber 56 to a small diameter hydraulic chamber 49 by opening a reverse flow checking opening and closing portion 61 by sliding movement of a stepped piston 16 forwardly, that is, fast fill and when the hydraulic pressure of the large diameter pressurizing chamber 56 rises, a control valve 86 escapes the hydraulic pressure of the large diameter pressurizing chamber 56 to a reservoir 12 to gradually lower in accordance with rise of the hydraulic pressure of the small diameter hydraulic chamber 49, thereby capable of reducing a strange feeling in a pedal feeling caused by sudden pressure release of the large diameter pressuring chamber 56.

摘要翻译： 本发明的主缸通过向前倾斜阶梯式活塞16的滑动打开反向流动检查开闭部61来将制动液从大直径加压室56供给到小直径液压室49，即快速填充 并且当大直径加压室56的液压上升时，控制阀86将大直径加压室56的液压从储存器12排出，以便随着小直径液压室的液压升高逐渐降低 从而能够减小由大直径加压室56的突然的压力释放引起的踏板感觉的奇怪的感觉。

公开(公告)号：US06625981B2

公开(公告)日：2003-09-30

申请号：US10050100

申请日：2002-01-18

申请人： Junichi Ikeda ,  Hiromi Ando ,  Atsuya Koshu

发明人： Junichi Ikeda ,  Hiromi Ando ,  Atsuya Koshu

IPC分类号： F16D3102

CPC分类号： F02M35/10229 ,  B60T13/52 ,  F02M35/10

摘要： There is disclosed a pneumatic booster having a vacuum chamber connected to an intake pipe of an engine. An air outlet of an ejector is connected to the intake pipe through a vacuum control valve, and an air inlet of the ejector is connected to an air cleaner. A vacuum pick-up port of the ejector is connected to the vacuum chamber of a booster body. The vacuum control valve comprises a control chamber and a control piston, and the negative pressure in the booster is introduced into the control chamber and acts on the control piston. When the negative pressure in the booster is insufficient, the control piston acts to open the control valve and a negative pressure is supplied from the ejector to the vacuum chamber. When the negative pressure in the booster is sufficiently high, the control piston acts to close the control valve and stops the operation of the ejector, thus reducing an effect of the ejector with respect to an air/fuel ratio of the engine.