摘要:
The transdermal administration device of the present invention includes: a needle support with a plurality of microneedles formed at a tip portion thereof; a holder with the needle support placed therein, allowing the needle support to protrude itself therefrom and retract therein; and a cap for covering the microneedles, and further includes: a spring member placed between the needle support and the holder, for biasing the needle support in a protruding direction; an engaging portion at a base of the needle support; and an engaged portion capable of engaging the engaging portion, formed in the holder, where the engaging portion of the needle support can be locked with the engaged portion of the holder when the needle support is retracted in the holder.
摘要:
The transdermal administration device of the present invention includes: a needle support with a plurality of microneedles formed at a tip portion thereof; a holder with the needle support placed therein, allowing the needle support to protrude itself therefrom and retract therein; and a cap for covering the microneedles, and further includes: a spring member placed between the needle support and the holder, for biasing the needle support in a protruding direction; an engaging portion at a base of the needle support; and an engaged portion capable of engaging the engaging portion, formed in the holder, where the engaging portion of the needle support can be locked with the engaged portion of the holder when the needle support is retracted in the holder.
摘要:
The transdermal administration device of the present invention includes: a device body including a needle form body, which includes a plurality of microneedles formed on a surface thereof and is provided with a fluid passage hole through the front surface to a back surface thereof, and a medical fluid filling section for providing a medical fluid to the back surface of the needle form body; a stratum corneum peeling system; and a connection section for connecting the device body and the stratum corneum peeling system, where the stratum corneum peeling system is connected to the device body by the connection section such that the microneedles of the needle form body of the device body are positioned in an area of a skin surface in which a stratum corneum is peeled by the stratum corneum peeling system.
摘要:
Disclosed is a substance which has a low molecular weight, can be applied in a simpler manner, and has an immunopotentiating activity against cancer and/or a microorganism-mediated infectious disease.An EP4 agonist exhibits an immunopotentiating activity through the activation of a cytotoxic T cell, and is therefore useful for the prevention and/or treatment of cancer or a microorganism-mediated infection disease.
摘要:
An object is to provide a method of cutting a laminate film by a circular cutter having a blade around its peripheral edge portion, including rotating the circular cutter at a blade peripheral speed of Vr by a rotational device in a forward rotational direction relative to the cutting direction, while, at the same time, moving the circular cutter at a moving speed of Vc, thereby cutting the laminate film, wherein the relative cutting speed V calculated by subtracting the blade peripheral speed Vr from the moving speed Vc falls within a range of not less than −50 m/min to not more than 30 m/min.
摘要:
A color apparatus includes an electroexpansive actuator, a unit for supplying a charge to the electroexpansive actuator, and a unit for controlling an amount of charge discharged from the electroexpansive actuator, and a stroke of the electroexpansive actuator is controlled in accordance with the amount of charge discharged therefrom. When such an electroexpansive actuator is applied to a control apparatus for a fuel injection valve, a fuel injection amount per ON/OFF operation of the fuel injection valve or a fuel injection rate can be freely controlled.
摘要:
A concrete breaker, in which in breaking a concrete structure, the inclination of the main chisel is maintained within a desired angle by a limit switch to prevent the chisel receiving bed and the ram from being damaged at least two mini-chisels disposed opposite the main chisel are slidably arranged and driving means for these chisels are encased in a machine frame provided with machine beds so that the machine body may be formed smaller and lighter in weight.
摘要:
A gas/liquid separator device includes a separator, such as a cyclone type separator, provided in a blowby gas passage for introducing a blowby gas from a blowby gas chamber of an internal combustion engine, an oil accumulator in the form of a container for accumulating separated and condensed oil mist, another passage provided separately from the blowby gas passage for returning the oil from the oil accumulator to an oil collection chamber, and a communication blocking element for blocking a communication between the oil accumulator and the oil collection chamber while the engine is running.
摘要:
A fuel injection system in which a fuel injector having a fuel pressure control chamber formed therein to create a pressure which forces a needle valve in the closing direction to open and close the nozzle hole, an accumulator to retain fuel discharged from the nozzle hole, and a fuel injector provided at each of the cylinders of the engine, are connected to the fuel injection pump by a single piping system without utilizing a special distribution mechanism. The volume of the fuel pressure control chamber in the fuel injector can be changed by a piezo-actuator. A check valve is provided at a half way point of the piping which leads the fuel fed under pressure from the fuel injection pump to the fuel injector into the fuel pressure control chamber and the accumulator, so that the fuel is fed through the check valve into the fuel pressure control chamber and the accumulator.