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    Horseshoe crab amebocyte lysate factor G activation inhibitor
    3.
    发明授权
    Horseshoe crab amebocyte lysate factor G activation inhibitor 失效
    HORSESHOE CRAB AMEBOCYTE LYSATE因子G激活抑制剂

    公开(公告)号：US5155032A

    公开(公告)日：1992-10-13

    申请号：US474057

    申请日：1990-05-01

    申请人： Shigenori Tanaka ,  Jun Aketagawa ,  Makoto Ohki ,  Shoji Takahashi ,  Hiroshi Tamura ,  Yuko Shibata

    发明人： Shigenori Tanaka ,  Jun Aketagawa ,  Makoto Ohki ,  Shoji Takahashi ,  Hiroshi Tamura ,  Yuko Shibata

    IPC分类号： C07H3/06 ,  C08B37/00 ,  G01N33/579

    CPC分类号： C08B37/0024 ,  C07H3/06 ,  G01N33/579

    摘要： This invention relates to a horseshoe crab amebocyte lysate factor G activation inhibitor comprising as an active ingredient a polyglycoside containing at least one poly-(1.fwdarw.3)-.beta.-D-glucoside structure portion consisting of 2 to 370 (1.fwdarw.3)-.beta.-D-glucoside structural units of the following formula ##STR1## which are continuously bound to one another. This inhibitor is useful for inhibiting the activation of factor G which may exist in horseshoe crab amebocyte lysate used in the Limulus test.

    摘要翻译： PCT No.PCT / JP89 / 00903 Sec。 371日期1990年5月1日 102（e）日期1990年5月1日PCT提交1989年9月1日PCT公布。 公开号WO90 / 02951 日本3月22日，1990年。本发明涉及一种马蹄形蟹细胞裂解物因子G激活抑制剂，其包含含有至少一种由（2）〜（1→3）-β-D-葡萄糖苷结构部分组成的多糖苷的多糖苷作为活性成分 到具有连续结合的下式（IMAGE）的370（1-> 3）-β-D-葡萄糖苷结构单元。 该抑制剂可用于抑制鲎试验中使用的马蹄蟹血小板裂解物中可能存在的因子G的活化。

    PRO-CLOTTING ENZYME, AND METHOD FOR DETECTION OF ENDOTOXIN OR (1-3)-BETA-D-GLUCAN USING THE SAME
    4.
    发明申请
    PRO-CLOTTING ENZYME, AND METHOD FOR DETECTION OF ENDOTOXIN OR (1-3)-BETA-D-GLUCAN USING THE SAME 审中-公开
    PRO-CLOTTING ENZYME和用于检测内毒素或（1-3）-BETA-D-GLUCAN的方法

    公开(公告)号：US20090208995A1

    公开(公告)日：2009-08-20

    申请号：US12307890

    申请日：2007-07-06

    申请人： Hiroshi Tamura ,  Shoji Takahashi

    发明人： Hiroshi Tamura ,  Shoji Takahashi

    IPC分类号： C12Q1/26 ,  C12P21/06 ,  C12N9/00 ,  C12N7/00 ,  C12N5/06 ,  C07H21/04

    CPC分类号： C12Q1/56 ,  C07K14/43509 ,  C12N9/6402 ,  C12N9/6408 ,  C12N2799/026 ,  G01N33/579 ,  Y02P20/582

    摘要： Objects of the present invention are to provide a DNA fragment encoding a limulus-derived pro-clotting enzyme, a virus harboring the DNA fragment, a cell harboring the virus, a method of producing the pro-clotting enzyme by use of the cell, and means for assaying an endotoxin or (1→3)-β-D-glucan employing the enzyme, wherein these elements are capable of producing an endotoxin or (1→3)-β-D-glucan assay reagent of satisfactory quality, steadily, at low cost, and on a large scale. In the present invention, for example, a DNA fragment encoding a protein having an amino acid sequence defined by SEQ ID NO: 4 is selected as a nucleic acid fragment encoding a limulus-derived pro-clotting enzyme, and the corresponding recombinant pro-clotting enzyme. Use of the enzyme can provide a high-sensitivity method and kit for detecting (1→3)-β-D-glucan and an endotoxin, utilizing a cascade reaction system in a horseshoe crab lysate.

    摘要翻译： 本发明的目的是提供编码鲎来源的凝血酶的DNA片段，携带DNA片段的病毒，携带病毒的细胞，使用该细胞产生促凝酶的方法，以及 用于使用酶测定内毒素或（1-> 3）-β-D-葡聚糖的方法，其中这些元件能够产生令人满意质量的内毒素或（1-> 3）-β-D-葡聚糖测定试剂， 稳定地，以低成本，大规模。 在本发明中，例如，选择编码具有SEQ ID NO：4所定义的氨基酸序列的蛋白质的DNA片段作为编码鲎来源的凝血酶的核酸片段，将相应的重组凝血酶 酶。 使用酶可以提供用于检测（1→3）-β-D-葡聚糖和内毒素的高灵敏度方法和试剂盒，利用马蹄蟹溶解产物中的级联反应系统。

    Cassette for radiographic imaging and cassette loading orientation detection device
    5.
    发明授权
    Cassette for radiographic imaging and cassette loading orientation detection device 有权
    用于放射成像和盒式装载方向检测装置的盒

    公开(公告)号：US08616766B2

    公开(公告)日：2013-12-31

    申请号：US12923507

    申请日：2010-09-24

    申请人： Shoji Takahashi ,  Daisuke Utsunomiya ,  Mitsuaki Uchida

    发明人： Shoji Takahashi ,  Daisuke Utsunomiya ,  Mitsuaki Uchida

    IPC分类号： H01J31/49

    CPC分类号： G03B42/04 ,  A61B6/4283 ,  A61B6/547

    摘要： A cassette for X-ray imaging includes a cassette body storing an X-ray detector. Three reflective optical sensors are arranged on an upper end side of a rear surface, which is opposite to a detection surface, of the cassette body. An X-ray detection device for supine-posture imaging has a table. The X-ray detection device includes a tray to which the cassette is loaded. Markers for identifying a loading orientation of the cassette are attached to the tray. The reflective optical sensors read out the markers and detect the loading orientation of the cassette.

    摘要翻译： 用于X射线成像的盒包括存储X射线检测器的盒体。 三个反射光学传感器布置在盒体的与检测表面相对的后表面的上端侧。 用于仰卧姿态成像的X射线检测装置具有表格。 X射线检测装置包括一个托盘，盒装载到该托盘上。 用于识别盒的装载方向的标记被附接到托盘。 反射光学传感器读出标记并检测盒的装载方向。

    X-ray imaging device, method for detecting deviation of flat panel detector, and program for the same
    6.
    发明授权
    X-ray imaging device, method for detecting deviation of flat panel detector, and program for the same 有权
    X射线成像装置，平板检测器偏差检测方法及程序

    公开(公告)号：US08313238B2

    公开(公告)日：2012-11-20

    申请号：US12805061

    申请日：2010-07-09

    申请人： Shoji Takahashi

    发明人： Shoji Takahashi

    IPC分类号： A61B6/08

    CPC分类号： A61B6/587 ,  A61B6/583 ,  A61B6/588

    摘要： An X-ray imaging device includes an X-ray generator, a filter plate detachably attached to an X-ray outlet of the X-ray generator, and a FPD. The filter plate has a plurality of circular markers of different sizes. The smallest marker is disposed at the center of the filter plate. The other markers are disposed on lines radiating from the smallest marker in increasing order of size and at regular intervals. An X-ray radiation beam passes through the markers and patient's body, and is incident upon an imaging surface of the FPD. The FPD produces a preliminary radiographic image from the incident X-ray radiation beam. A deviation vector detector chooses adjoining two marker images of different sizes from the preliminary radiographic image, and identifies to which markers the marker images correspond based on a size ratio. Then, the deviation vector detector determines the center of an X-ray field.

    摘要翻译： X射线成像装置包括X射线发生器，可拆卸地附接到X射线发生器的X射线出口的滤光板和FPD。 滤板具有不同尺寸的多个圆形标记。 最小的标记设置在过滤板的中心。 其他标记物以规模间隔的增加顺序设置在从最小标记物辐射的线上。 X射线辐射束穿过标记物和患者身体，并入射到FPD的成像表面上。 FPD从入射的X射线辐射束产生初步的放射线照相图像。 偏差矢量检测器从预备放射线照相图像中选择不同尺寸的邻接的两个标记图像，并且基于尺寸比来识别标记图像对应于哪个标记。 然后，偏差矢量检测器确定X射线场的中心。

    Cassette accommodating device, and radiation detection system
    7.
    发明授权
    Cassette accommodating device, and radiation detection system 有权
    盒式收纳装置和放射线检测系统

    公开(公告)号：US08292504B2

    公开(公告)日：2012-10-23

    申请号：US12844845

    申请日：2010-07-28

    申请人： Akihito Bettouyashiki ,  Yoshiki Takeoka ,  Yutaka Yoshida ,  Keiji Tsubota ,  Shoji Takahashi ,  Yasunori Ohta ,  Naoyuki Nishino

    发明人： Akihito Bettouyashiki ,  Yoshiki Takeoka ,  Yutaka Yoshida ,  Keiji Tsubota ,  Shoji Takahashi ,  Yasunori Ohta ,  Naoyuki Nishino

    IPC分类号： H01J31/49

    CPC分类号： G03B42/025 ,  H02J7/0044

    摘要： A cassette accommodating device accommodates casings of a plurality of sizes. Each casing is detachably inserted with a cassette installed with a rechargeable battery and a radiation detection unit that is supplied with power from the rechargeable battery and generates a radiographic image according to an amount of received radiation. Each casing is provided on at least one of two connected side faces with a power receiving unit that receives power for charging the rechargeable battery. The device comprises a groove portion, formed with a sloping face that faces one of the two side faces of an accommodated casing, and a bottom face that faces the other of the two side faces of the accommodated casing. The bottom face is inclined such that the casing moves toward the sloping face when the casing is accommodated. A power supply unit is formed to the sloping face and/or the bottom face so as to supply power to the power receiving unit when the casing has been accommodated.

    摘要翻译： 盒式收纳装置容纳多种尺寸的外壳。 每个壳体可拆卸地插入安装有可再充电电池的盒和从可再充电电池供电的放射线检测单元，并根据接收到的辐射量产生放射线图像。 每个壳体设置在两个连接的侧面中的至少一个上，其具有接收用于为可再充电电池充电的电力的电力接收单元。 该装置包括形成有倾斜面的槽部，该倾斜面朝向容纳壳体的两个侧面中的一个，以及面对面容纳壳体的两个侧面中的另一侧的底面。 底面是倾斜的，使得当容纳壳体时壳体向倾斜面移动。 电源单元形成在倾斜面和/或底面上，以便在容纳壳体时向电力接收单元供电。

    Method of measuring lipoarabinomannan and application thereof
    8.
    发明授权
    Method of measuring lipoarabinomannan and application thereof 有权
    测量脂多巴胺甘露聚糖的方法及其应用

    公开(公告)号：US07851179B2

    公开(公告)日：2010-12-14

    申请号：US10584071

    申请日：2004-12-22

    申请人： Shigenori Tanaka ,  Shoji Takahashi

    发明人： Shigenori Tanaka ,  Shoji Takahashi

    IPC分类号： C12Q1/04

    CPC分类号： G01N33/579 ,  G01N33/56911 ,  G01N2400/50

    摘要： A method for measuring LAM and a method for detecting an acid-fast bacterium, which comprise at least a step of allowing a Limulus reagent to contact with a LAM-containing sample, a method for removing reactivity of LAM with a Limulus reagent, which comprises at least a step of allowing a predetermined substance to coexist with a LAM-containing sample; a method for measuring Et in a LAM-containing sample and a method for detecting an Et-related disease, which each is a method for measuring an endotoxin using a Limulus reagent, which comprises at least a step of removing reactivity of LAM with a Limulus reagent by the above-described removing method; a method for measuring BG in a LAM-containing sample and a method for detecting mycosis, which is a method for measuring BG using a Limulus reagent which comprises at least a step of removing reactivity of LAM with a Limulus reagent by the described-described removing method; and the like.

    摘要翻译： 一种用于测量LAM的方法和一种用于检测耐酸细菌的方法，其包括使鲎试剂与含LAM的样品接触的步骤，用于除去LAM与鲎试剂的反应性的方法，所述方法包括 至少一个允许预定物质与含LAM的样品共存的步骤; 用于测量含LAM的样品中的Et的方法和用于检测Et相关疾病的方法，其各自是使用鲎试剂测量内毒素的方法，该方法至少包括除去LAM与鲎的反应性的步骤 试剂通过上述去除方法; 用于测量含有LAM的样品中的BG的方法和用于检测真菌病的方法，其是使用鲎试剂测量BG的方法，所述方法至少包括通过所述除去的方法除去LAM与鲎试剂的反应性的步骤 方法; 等等。

    Ignition coil and manufacturing method and apparatus thereof
    9.
    发明授权
    Ignition coil and manufacturing method and apparatus thereof 有权
    点火线圈及其制造方法和装置

    公开(公告)号：US07394342B2

    公开(公告)日：2008-07-01

    申请号：US11505891

    申请日：2006-08-18

    申请人： Kazuhide Kawai ,  Shoji Takahashi ,  Chihiro Ikedo

    发明人： Kazuhide Kawai ,  Shoji Takahashi ,  Chihiro Ikedo

    IPC分类号： H01F27/24

    CPC分类号： H01F38/12 ,  H01F27/022 ,  H01F27/324 ,  H01F2038/122

    摘要： An axial end portion of a dielectric sheet, which is wound around a central core of an ignition coil, includes an axially projecting portion, which projects from an axial end surface of the central core positioned radially inward of primary and secondary coils in a case. An inner peripheral side axial end corner and an outer peripheral side axial end corner in the axially projecting portion are respectively formed into a blunt smooth round shape. Dielectric resin is filled in spaces in the case. Alternatively, the axially projecting portion may have a folded end portion, which includes a plurality of generally arcuate segments folded one after another on one circumferential side thereof.

    摘要翻译： 卷绕在点火线圈的中心芯上的电介质片的轴向端部包括从中心芯的轴向端面突出的轴向突出部，该中心芯的轴向端面位于壳体内的初级线圈和次级线圈的径向内侧。 轴向突出部分中的内周侧轴向端角和外周侧轴向端角分别形成钝平的圆形。 介质树脂填充在箱子的空间中。 或者，轴向突出部分可以具有折叠端部，该折叠端部包括在其一个圆周侧上一个接一个地折叠的多个大致弓形的段。